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Review Permax Safety Reports submitted to FDA

Total Permax reports: 39.
Permax FDA safety alerts: 2003 2004 2007 .
Reported deaths: 4    Reported hospitalizations: 31.
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FDA Reported Permax Side Effects: depressed level of consciousness, loss of consciousness, interstitial lung disease, atrioventricular block complete, acanthoma, depression, condition aggravated, neuroleptic malignant syndrome, pulmonary alveolar haemorrhage, pleurisy, pleural effusion.
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Permax Side Effects Report #5671659-6
Physician from JAPAN reported PERMAX problem on Mar 05, 2008. Female patient, 81 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: basophil percentage decreased, eosinophilic pneumonia acute, interstitial lung disease, lymphocyte percentage decreased, lymphocyte stimulation test positive, monocyte percentage decreased, neutrophil percentage decreased, pleural calcification, pleural effusion. PERMAX dosage: unknown. During the same period patient was treated with SELEGILINE HYDROCHLORIDE, AMANTADINE, CLONAZEPAM, LEVODOPA BENSERAZIDE HYDROCHLO, LEVODOPA BENSERAZIDE HYDROCHLO. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5632030-6
PERMAX problem was reported by a Physician from JAPAN on Feb 04, 2008. Male patient, 74 years of age, weighting 149.9 lb, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, cardiac murmur, cardiomegaly, hepatic congestion, hip swelling, mitral valve incompetence, oedema genital, oedema peripheral. PERMAX dosage: unknown. During the same period patient was treated with CARBIDOPA AND LEVODOPA, ARTANE, DOMIN, PRAMIPEXOLE DIHYDROCHLORIDE, DONEPEZIL. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5636054-4
Consumer or non-health professional from JAPAN reported PERMAX problem on Feb 04, 2008. Female patient, 81 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: eosinophilic pneumonia acute, interstitial lung disease, lymphocyte stimulation test positive, pleural calcification, pleural effusion, pneumocystis jiroveci pneumonia, pneumonia cytomegaloviral, pneumonia primary atypical, pneumonitis. PERMAX dosage: unknown. During the same period patient was treated with SELEGILINE HYDROCHLORIDE, AMANTADINE, CLONAZEPAM, LEVODOPA BENSERAZIDE HYDROCHLO, LEVODOPA BENSERAZIDE HYDROCHLO. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5636815-1
PERMAX problem was reported by a Physician from JAPAN on Jan 24, 2008. Female patient, 77 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: aortic valve disease, hepatic function abnormal, inflammation, osteonecrosis, pericardial effusion. PERMAX dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Permax Side Effects Report #5584484-1
Health Professional from JAPAN reported PERMAX problem on Feb 09, 2007. Female patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: pleural effusion, tuberculosis. PERMAX dosage: unknown. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5584487-7
PERMAX problem was reported by a Physician from JAPAN on Apr 19, 2007. Male patient, 73 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: aphagia, pericardial effusion, pericarditis, pleural effusion. PERMAX dosage: unknown. During the same period patient was treated with MENESIT, PARMIPEXOLE, PROSTAL, HARNAL, MAGNESIUM OXIDE, MUCODYNE, MUCOSAL, AMBROXOL HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5584500-7
Pharmacist from JAPAN reported PERMAX problem on Dec 18, 2007. Female patient, child 1 years of age, weighting 22.05 lb, was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: vomiting. PERMAX dosage: unknown. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5598097-9
PERMAX problem was reported by a Physician from GERMANY on Jan 02, 2008. Male patient, 67 years of age, weighting 172.0 lb, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: congestive cardiomyopathy, dyspnoea, ejection fraction decreased, ventricular extrasystoles. PERMAX dosage: 3 MG; QD; PO. During the same period patient was treated with MADOPAR, TOREM, ALDACTONE, ASPIRIN, ACERBON, NOVODIGAL. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5614883-0
Consumer or non-health professional from JAPAN reported PERMAX problem on Jan 18, 2008. Female patient, 81 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease. PERMAX dosage: unknown. During the same period patient was treated with SELEGILINE HYDROCHLORIDE, AMANTADINE, CLONAZEPAM, LEVODOPA BENSERAZIDE HYDROCHLO. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5614884-2
PERMAX problem was reported by a Consumer or non-health professional from FRANCE on Nov 02, 2007. Male patient, 64 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: aortic valve incompetence, cardiac murmur, left ventricular hypertrophy, mitral valve incompetence, pulmonary valve incompetence, tricuspid valve incompetence. PERMAX dosage: 1.5 MG;TID;PO. During the same period patient was treated with DIFRAREL, MODOPAR, COMTAN. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5614885-4
Pharmacist from JAPAN reported PERMAX problem on Jan 17, 2008. Female patient, child 1 years of age, weighting 22.05 lb, was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: vomiting. PERMAX dosage: unknown. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5564261-8
PERMAX problem was reported by a Physician from JAPAN on Nov 27, 2007. Female patient, 85 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: aortic valve incompetence, blood ph decreased, blood pressure decreased, cardiac failure, haemodialysis, lymphadenopathy, mitral valve incompetence, pleural effusion. PERMAX dosage: unknown. During the same period patient was treated with MADOPAR, SEDIEL, LUVOX, ALOSENN, NAUZELIN. Patient was hospitalized. Patient died on 01/07/2006.

Permax Side Effects Report #5564262-X
Physician from GERMANY reported PERMAX problem on Nov 27, 2007. Male patient, 67 years of age, weighting 172.0 lb, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: congestive cardiomyopathy, dyspnoea, ejection fraction decreased, ventricular extrasystoles. PERMAX dosage: 3 MG;QD;PO. During the same period patient was treated with MADOPAR, TOREM, ALDACTONE, ACETYLSALICYLIC ACID SRT, ACERBON, NOVODIGAL. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5574236-0
PERMAX problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 11, 2007. Female patient, 42 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: chest pain, left ventricular hypertrophy, mitral valve incompetence, tricuspid valve incompetence. PERMAX dosage: 0.05 MG; QD;. Patient recovered.

Permax Side Effects Report #5510128-0
Physician from JAPAN reported PERMAX problem on Oct 22, 2007. Female patient, 74 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: cardiac aneurysm, cardiac disorder, cardiac failure congestive, cardiac valve disease, dyspnoea, echocardiogram abnormal, mitral valve prolapse, mitral valve sclerosis. PERMAX dosage: unknown. During the same period patient was treated with LEVODOPA BENSERAZIDE HYDROCHLORIDE, SIFROL, SYMMETREL. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5515922-8
PERMAX problem was reported by a Health Professional from GERMANY on Oct 29, 2007. Male patient, 54 years of age, was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: accidental exposure, circulatory collapse, hypotension. PERMAX dosage: unknown. During the same period patient was treated with RAMIPRIL. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5519293-2
Physician from JAPAN reported PERMAX problem on Nov 01, 2007. Female patient, 74 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: cardiac aneurysm, cardiac failure congestive, cardiac valve disease, mitral valve incompetence, myocardial infarction. PERMAX dosage: unknown. During the same period patient was treated with LEVODOPA BENSERAZIDE, HYDROCHLO, SYMMETREL, SIFROL. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5519299-3
PERMAX problem was reported by a Physician from JAPAN on Nov 02, 2007. Female patient, 85 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: aortic valve incompetence, blood pressure decreased, cardiac failure, disease recurrence, fatigue, haemodialysis, mitral valve incompetence, no therapeutic response, oedema peripheral. PERMAX dosage: unknown. During the same period patient was treated with MADOPAR, SEDIEL, LUVOX, ALOSENN, NAUZELIN. Patient was hospitalized. Patient died on 01/07/2006.

Permax Side Effects Report #5519301-9
Physician from JAPAN reported PERMAX problem on Nov 02, 2007. Female patient, 85 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: aortic valve incompetence, blood pressure decreased, cardiac failure, cardiac murmur, haemodialysis, lymphadenopathy, mitral valve incompetence, oedema. PERMAX dosage: unknown. During the same period patient was treated with MADOPAR, SEDIEL, LUVOX, ALOSENN, NAUZELIN. Patient was hospitalized. Patient died on 01/07/2006.

Permax Side Effects Report #5519302-0
PERMAX problem was reported by a Physician from JAPAN on Nov 02, 2007. Male patient, 79 years of age, weighting 115.1 lb, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: altered state of consciousness, dehydration, hallucination, visual, neuroleptic malignant syndrome, somnolence, white blood cell count increased. PERMAX dosage: unknown. During the same period patient was treated with NEODOPASOL, RISPERIDINE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5526190-5
Physician from GERMANY reported PERMAX problem on Nov 02, 2007. Male patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: amyloidosis, anaemia, atelectasis, depression, gamma-glutamyltransferase increased, pericarditis constrictive, pleural effusion, pleural fibrosis, pneumonia. PERMAX dosage: 1 MG;QID;PO. During the same period patient was treated with LEVODOPA, CLOZAPINE, DIOVAN HCT, CARBIDOPA, COMTESS, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5527933-7
PERMAX problem was reported by a Physician from JAPAN on Nov 12, 2007. Male patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, blood pressure abnormal, cardiac failure, cardiac murmur, carotid artery disease, chest pain, dyspnoea exertional, fatigue. PERMAX dosage: unknown. During the same period patient was treated with CABERGOLINE, SELEGILINE, HYDROCHLORIDE, RIVOTRIL, BLOPRESS. Patient was hospitalized. Patient died on 05/09/2005.

Permax Side Effects Report #5532158-5
Physician from JAPAN reported PERMAX problem on Nov 16, 2007. Female patient, 74 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: cardiac aneurysm, cardiac disorder, cardiac failure congestive, cardiac valve disease, hydrothorax, mitral valve incompetence, mitral valve sclerosis, myocardial infarction. PERMAX dosage: unknown. During the same period patient was treated with LEVODOPA BENSERAZIDE, HYDROCHLO, SIFROL, SYMMETREL. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5477474-0
PERMAX problem was reported by a Pharmacist from JAPAN on Sept 13, 2007. Male patient, 75 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: blepharospasm, condition aggravated, parkinson's disease, visual acuity reduced. PERMAX dosage: unknown. During the same period patient was treated with CABERGOLINE, SIFROL. Patient recovered.

Permax Side Effects Report #5483160-3
Consumer or non-health professional from ITALY reported PERMAX problem on Oct 03, 2007. Male patient, 54 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: retroperitoneal fibrosis. PERMAX dosage: 4 MG;QD;PO. During the same period patient was treated with LEVODOPA. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5451968-6
PERMAX problem was reported by a Health Professional from JAPAN on Aug 29, 2007. Male patient, 75 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: blepharospasm, condition aggravated, parkinson's disease, visual acuity reduced. PERMAX dosage: unknown. During the same period patient was treated with CABERGOLINE, SIFROL. Patient recovered.

Permax Side Effects Report #5473234-5
Consumer or non-health professional from ITALY reported PERMAX problem on Sept 18, 2007. Male patient, 54 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: retroperitoneal fibrosis, urethral stenosis. PERMAX dosage: 4 MG; QD; PO. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5404725-0
PERMAX problem was reported by a Health Professional from JAPAN on July 26, 2007. Male patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, interstitial lung disease, lupus-like syndrome, platelet count decreased, pleural effusion, pleurisy, pulmonary alveolar haemorrhage. PERMAX dosage: unknown. During the same period patient was treated with SYMMETREL, MADOPAR. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5416523-2
Physician from JAPAN reported PERMAX problem on Aug 02, 2007. Male patient, 73 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: ascites, colon operation. PERMAX dosage: unknown. During the same period patient was treated with BROMOCRIPTINE MESYLATE, NEO DOPASTON, SELEGILINE HYDROCHLORIDE, DEPAS, PURSENNID, LAXOBERON, MAGNESIUM OXIDE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5385246-0
PERMAX problem was reported by a Consumer or non-health professional from UNITED STATES on June 15, 2007. Female patient, 45 years of age, was diagnosed with restless legs syndrome and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: acanthoma, antinuclear antibody positive, arthropathy, atrioventricular block complete, blood iron increased, bursitis, cardiac murmur, carotid bruit, cervical cyst. PERMAX dosage: unknown. During the same period patient was treated with NARBALEK, ULTRAM, PRAMIPEXOLE DIHYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5386011-0
Health Professional from JAPAN reported PERMAX problem on July 03, 2007. Male patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, interstitial lung disease, platelet count decreased, pleural effusion, pleurisy, pulmonary alveolar haemorrhage, systemic lupus erythematosus. PERMAX dosage: unknown. Patient recovered.

Permax Side Effects Report #5387178-0
PERMAX problem was reported by a Consumer or non-health professional from UNITED STATES on July 02, 2007. Female patient, 45 years of age, was diagnosed with restless legs syndrome and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: acanthoma, alanine aminotransferase increased, aspartate aminotransferase increased, atrioventricular block complete, blood alkaline phosphatase increased, blood bilirubin increased, blood iron increased, carotid bruit, cervical cyst. PERMAX dosage: unknown. During the same period patient was treated with NARBALEK, ULTRAM, PRAMIPEXOLE DIHYDROCHLORIDE, PREDNISONE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5394924-9
Physician from JAPAN reported PERMAX problem on July 10, 2007. Male patient, 73 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: ascites. PERMAX dosage: unknown. During the same period patient was treated with BROMOCRIPTINE MESYLATE. Patient recovered.

Permax Side Effects Report #5397254-4
PERMAX problem was reported by a Health Professional from JAPAN on July 16, 2007. Male patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, interstitial lung disease, pleural effusion, pleurisy, pulmonary alveolar haemorrhage, systemic lupus erythematosus. PERMAX dosage: unknown. Patient recovered.

Permax Side Effects Report #5385246-0
Consumer or non-health professional from UNITED STATES reported PERMAX problem on June 15, 2007. Female patient, 45 years of age, was diagnosed with restless legs syndrome and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: acanthoma, antinuclear antibody positive, arthropathy, atrioventricular block complete, blood iron increased, bursitis, cardiac murmur, carotid bruit, cervical cyst. PERMAX dosage: unknown. During the same period patient was treated with NARBALEK, ULTRAM, PRAMIPEXOLE DIHYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5386011-0
PERMAX problem was reported by a Health Professional from JAPAN on July 03, 2007. Male patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, interstitial lung disease, platelet count decreased, pleural effusion, pleurisy, pulmonary alveolar haemorrhage, systemic lupus erythematosus. PERMAX dosage: unknown. Patient recovered.

Permax Side Effects Report #5387178-0
Consumer or non-health professional from UNITED STATES reported PERMAX problem on July 02, 2007. Female patient, 45 years of age, was diagnosed with restless legs syndrome and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: acanthoma, alanine aminotransferase increased, aspartate aminotransferase increased, atrioventricular block complete, blood alkaline phosphatase increased, blood bilirubin increased, blood iron increased, carotid bruit, cervical cyst. PERMAX dosage: unknown. During the same period patient was treated with NARBALEK, ULTRAM, PRAMIPEXOLE DIHYDROCHLORIDE, PREDNISONE. Patient was hospitalized. Patient recovered.

Permax Side Effects Report #5394924-9
PERMAX problem was reported by a Physician from JAPAN on July 10, 2007. Male patient, 73 years of age, was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: ascites. PERMAX dosage: unknown. During the same period patient was treated with BROMOCRIPTINE MESYLATE. Patient recovered.

Permax Side Effects Report #5397254-4
Health Professional from JAPAN reported PERMAX problem on July 16, 2007. Male patient was diagnosed with parkinson's disease and was treated with PERMAX. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, interstitial lung disease, pleural effusion, pleurisy, pulmonary alveolar haemorrhage, systemic lupus erythematosus. PERMAX dosage: unknown. Patient recovered.


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basophil percentage decreased, eosinophilic pneumonia acute, interstitial lung disease, lymphocyte percentage decreased, lymphocyte stimulation test positive, monocyte percentage decreased, neutrophil percentage decreased, pleural calcification, pleural effusion, , was diagnosed with parkinson's disease and was diagnosed with parkinson's disease and was diagnosed with parkinson's disease and