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Phenergan Side Effects

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Phenergan Safety Reports reported to FDA

Total Phenergan reports: 36.
Phenergan FDA safety alerts: 2005 2006 .
Reported deaths: 7    Reported hospitalizations: 9.
Take Phenergan Side Effects Survey or Share Your Phenergan Story.
Reported Phenergan Side Effects: pain in extremity, thrombophlebitis superficial, oedema peripheral, infusion site pain, erythema, loss of consciousness, intentional overdose, rash macular, gangrene, cellulitis, contusion.
Phenergan Usage.
If you have questions about Phenergan, you can ask a Health Expert or Ask Patient Community about Phenergan.

Phenergan Side Effects Report #5208891-1
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Jan 11, 2007. Male patient, 35 years of age, weighting 155.0 lb, was diagnosed with nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: impaired work ability, injection site irritation, injection site pain, thrombophlebitis superficial. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5211898-1
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 16, 2007. Female patient, 75 years of age, weighting 110.0 lb, was diagnosed with nausea, vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: aphasia, speech disorder. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5214933-X
Pharmacist from UNITED STATES reported PHENERGAN problem on Jan 19, 2007. Female patient, weighting 89.60 lb, was diagnosed with nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: loss of consciousness, respiratory distress. PHENERGAN dosage: 25 MG ONCE IV BOLUS. Patient recovered.

Phenergan Side Effects Report #5243821-8
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 20, 2007. Male patient, 79 years of age, weighting 173.9 lb, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: dystonia. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5294770-0
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Apr 09, 2007. Male patient, 27 years of age, weighting 186.3 lb, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: muscle spasms. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5313793-6
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 27, 2007. Female patient, 35 years of age, was diagnosed with nausea, vomiting, breast cancer and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: chills, dyspnoea, muscle twitching. PHENERGAN dosage: unknown. During the same period patient was treated with GEMZAR, TAXOL, COMPAZINE. Patient recovered.

Phenergan Side Effects Report #5330957-6
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on May 18, 2007. Female patient, 75 years of age, weighting 126.0 lb, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: feeling abnormal, loss of consciousness, speech disorder. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5077777-8
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on July 24, 2006. Female patient, child 7 years of age, was diagnosed with gastroenteritis viral, vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: accidental overdose, coma, convulsion, cyanosis, dyspnoea, loss of consciousness, respiratory arrest, respiratory distress. PHENERGAN dosage: unknown. During the same period patient was treated with CHLOROMYCETIN. Patient was hospitalized. Patient died on 01/01/1962.

Phenergan Side Effects Report #5088765-X
Pharmacist from UNITED STATES reported PHENERGAN problem on Aug 24, 2006. Male patient, 82 years of age, weighting 150.6 lb, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: neuroleptic malignant syndrome. PHENERGAN dosage: 25 MG IV. Patient was hospitalized. Patient recovered.

Phenergan Side Effects Report #5088766-1
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2006. Male patient, weighting 28.66 lb, was diagnosed with viral infection and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: no adverse effect. PHENERGAN dosage: 12.5 MG. ONCE IV. Patient recovered.

Phenergan Side Effects Report #5092253-4
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Aug 28, 2006. Female patient, 24 years of age, weighting 110.0 lb, was diagnosed with nausea, vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: crying, infusion site pain, pain in extremity, phlebitis, screaming, sensation of pressure. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5093794-6
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 29, 2006. Female patient, 55 years of age, weighting 146.0 lb, was diagnosed with nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: contusion, infection, infusion site pain, oedema peripheral, paraesthesia, skin discolouration, thrombophlebitis superficial, vein disorder. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5094231-8
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Aug 30, 2006. Female patient, 55 years of age, weighting 148.0 lb, was diagnosed with nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: contusion, infection, infusion site pain, oedema peripheral, paraesthesia, skin discolouration, thrombophlebitis superficial, vein disorder. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5113838-2
PHENERGAN problem was reported by a Pharmacist from UNITED STATES on Sept 21, 2006. Male patient, 40 years of age, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: restless legs syndrome. PHENERGAN dosage: 20 MG X1 IV. Patient recovered.

Phenergan Side Effects Report #5117163-5
Pharmacist from UNITED STATES reported PHENERGAN problem on Sept 27, 2006. Male patient, 23 years of age, weighting 146.4 lb, was diagnosed with vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: cellulitis, thrombophlebitis, vomiting. PHENERGAN dosage: 12.5 MG ONCE IVP. Patient recovered.

Phenergan Side Effects Report #5117164-7
PHENERGAN problem was reported by a Pharmacist from UNITED STATES on Sept 27, 2006. Female patient, 64 years of age, was diagnosed with dizziness, nausea, vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: cellulitis, erythema, oedema peripheral. PHENERGAN dosage: 25 MG ONCE IV. Patient recovered.

Phenergan Side Effects Report #5117301-4
Pharmacist from UNITED STATES reported PHENERGAN problem on Sept 27, 2006. Female patient, 39 years of age, weighting 120.2 lb, was diagnosed with migraine and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: thrombophlebitis. PHENERGAN dosage: 12.5 MG ONCE IV. Patient recovered.

Phenergan Side Effects Report #5117302-6
PHENERGAN problem was reported by a Pharmacist from UNITED STATES on Sept 27, 2006. Male patient, weighting 200.0 lb, was diagnosed with nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: oedema peripheral, pain in extremity, thrombophlebitis superficial. PHENERGAN dosage: 12.5 MG Q6H PRN IV X 2 DOSES. Patient was hospitalized. Patient recovered.

Phenergan Side Effects Report #5122164-7
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Sept 20, 2006. Female patient, 79 years of age, weighting 116.1 lb, was diagnosed with vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome. PHENERGAN dosage: unknown. During the same period patient was treated with LASIX, ALBUTEROL. Patient died on 08/08/2006.

Phenergan Side Effects Report #5127423-X
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 13, 2006. Male patient, 42 years of age, weighting 223.0 lb, was diagnosed with nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, injection site erythema, injection site irritation, injection site thrombosis. PHENERGAN dosage: 25 MG ONCE IV PUSH IN WRIST. Patient was hospitalized. Patient recovered.

Phenergan Side Effects Report #5130282-2
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Oct 18, 2006. Female patient, 85 years of age, weighting 125.0 lb, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: amnesia, dementia, hallucination, loss of consciousness, mental disorder. PHENERGAN dosage: unknown. Patient was hospitalized. Patient recovered.

Phenergan Side Effects Report #5143834-0
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 02, 2006. Male patient, weighting 30.00 lb, was diagnosed with cough and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: attention deficit/hyperactivity disorder, breath sounds abnormal, complex partial seizures, convulsion, depressed level of consciousness, dyspnoea, educational problem, eye rolling, febrile convulsion. PHENERGAN dosage: unknown. Patient was hospitalized. Patient recovered.

Phenergan Side Effects Report #5153178-9
Pharmacist from UNITED STATES reported PHENERGAN problem on Nov 14, 2006. Female patient was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: burning sensation, cellulitis, contusion, erythema, hypoaesthesia, oedema peripheral, pain. PHENERGAN dosage: INJECTABLE AMPUL 25MG/ML. Patient recovered.

Phenergan Side Effects Report #5153180-7
PHENERGAN problem was reported by a Pharmacist from UNITED STATES on Nov 14, 2006. Female patient was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: burning sensation, injection site irritation, injection site swelling, pain. PHENERGAN dosage: AMPUL 25 MG/ML INJECTABLE. Patient recovered.

Phenergan Side Effects Report #5153251-5
Pharmacist from UNITED STATES reported PHENERGAN problem on Nov 14, 2006. Female patient, 32 years of age, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: erythema, finger amputation, gangrene, iatrogenic injury, infusion site pain, local swelling, peripheral coldness, rash macular. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5155775-3
PHENERGAN problem was reported by a Physician from UNITED STATES on Nov 01, 2006. Female patient, 19 years of age, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: intentional overdose. PHENERGAN dosage: unknown. During the same period patient was treated with COCAINE, METHADONE. Patient died on 01/01/2005.

Phenergan Side Effects Report #5155948-X
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Nov 01, 2006. Female patient, 19 years of age, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: intentional overdose. PHENERGAN dosage: unknown. During the same period patient was treated with COCAINE, METHADONE. Patient died on 01/01/2005.

Phenergan Side Effects Report #5155949-1
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 01, 2006. Female patient, 28 years of age, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: intentional overdose. PHENERGAN dosage: unknown. During the same period patient was treated with COCAINE, METHADONE. Patient died on 01/01/2005.

Phenergan Side Effects Report #5163803-4
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Nov 29, 2006. Female patient, 83 years of age, weighting 89.00 lb, was diagnosed with nausea, vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: arm amputation, arterial spasm, gangrene, poor peripheral circulation. PHENERGAN dosage: 12.5 MG INTRA-ARTER. Patient was hospitalized. Patient recovered.

Phenergan Side Effects Report #5162922-6
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 27, 2006. Female patient, 58 years of age, weighting 110.0 lb, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: blood albumin decreased, blood alkaline phosphatase increased. PHENERGAN dosage: 25 MG PRN Q6H. During the same period patient was treated with ZOFRAN, NEULASTA, LEXAPRO, POTASSIUM CHLORIDE, LASIX, TOPROL, LORTAB. Patient died on 11/13/2006.

Phenergan Side Effects Report #5168633-5
Consumer or non-health professional from UNITED STATES reported PHENERGAN problem on Dec 06, 2006. Male patient, 48 years of age, weighting 194.7 lb, was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: rash. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5378095-0
PHENERGAN problem was reported by a Pharmacist from UNITED STATES on July 02, 2007. Female patient, 72 years of age, weighting 174.2 lb, was diagnosed with nausea, vomiting and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: asthenia, body temperature increased, cough, dehydration, depressed level of consciousness, extrapyramidal disorder, lethargy, pain, restlessness. PHENERGAN dosage: 12.5MG IV SLOW PUSH X1. During the same period patient was treated with ENALAPRIL, ARICEPT, ASPIRIN, VIT B, PLAVIX, METFORMIN, TRAMADOL. Patient was hospitalized. Patient recovered.

Phenergan Side Effects Report #5396732-1
Health Professional from UNITED STATES reported PHENERGAN problem on July 13, 2007. Female patient was diagnosed with nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: foetal growth retardation. PHENERGAN dosage: unknown. Patient died on 07/01/2007.

Phenergan Side Effects Report #5403204-4
PHENERGAN problem was reported by a Consumer or non-health professional from UNITED STATES on July 23, 2007. Female patient, 29 years of age, weighting 130.1 lb, was diagnosed with nausea, pain and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: arterial injury, gangrene, hypoaesthesia, infusion site pain, pain in extremity, postoperative wound infection. PHENERGAN dosage: unknown. During the same period patient was treated with DILAUDID, CHLORIDE. Patient was hospitalized and became disabled. Patient recovered.

Phenergan Side Effects Report #5451243-X
Health Professional from UNITED STATES reported PHENERGAN problem on Sept 11, 2007. Male patient, 31 years of age, weighting 187.5 lb, was diagnosed with abdominal pain and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: rash, urticaria. PHENERGAN dosage: unknown. Patient recovered.

Phenergan Side Effects Report #5463001-0
PHENERGAN problem was reported by a Physician from UNITED STATES on Sept 18, 2007. Female patient, weighting 145.0 lb, was diagnosed with migraine, nausea and was treated with PHENERGAN. After drug was administered, patient experienced the following problems/side effects: erythema, fasciitis, injection site discolouration, injection site reaction, injection site swelling, injection site warmth, myositis, pain in extremity, pyrexia. PHENERGAN dosage: unknown. During the same period patient was treated with TORADOL, BENADRYL, TOPAMAX, STADOL, PHRENALIN. Patient recovered.


Drug Information: Promethazine

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682284.html

(proe meth' a zeen)

IMPORTANT WARNING:

Promethazine may cause breathing to slow or stop, and may cause death in children. Promethazine should not be given to babies or children who are younger than 2 years old and should be given with caution to children who are 2 years of age or older. Combination products containing promethazine and codeine should not be given to children younger than 16 years old. Promethazine should not routinely be used to treat vomiting in children; it should only be used in specific cases when a doctor decides that it is needed. Tell your child's doctor if your child has any condition that affects his/her breathing such as lung disease, asthma, or sleep apnea (stops breathing for short periods of time during sleep). Tell your doctor or pharmacist about all the medications your child is taking, especially barbiturates such as phenobarbital (Luminal), medications for anxiety, narcotic medications for pain, sedatives, sleeping pills, and tranquilizers. Call your child's doctor immediately and get emergency medical treatment if your child has difficulty breathing, wheezes, slows or pauses in breathing, or stops breathing. Talk to your doctor about the risks of giving promethazine to your child.

Why is this medication prescribed?

Promethazine is used to relieve the symptoms of allergic reactions such as allergic rhinitis (runny nose and watery eyes caused by allergy to pollen, mold or dust), allergic conjunctivitis (red, watery eyes caused by allergies), allergic skin reactions, and allergic reactions to blood or plasma products. Promethazine is used with other medications to treat anaphylaxis (sudden, severe allergic reactions) and the symptoms of the common cold such as sneezing, cough, and runny nose. Promethazine is also used to relax and sedate patients before and after surgery, during labor, and at other times. Promethazine is also used to prevent and control nausea and vomiting that may occur after surgery, and with other medications to help relieve pain after surgery. Promethazine is also used to prevent and treat motion sickness. Promethazine helps control symptoms, but will not treat the cause of the symptoms or speed recovery. Promethazine is in a class of medications called phenothiazines. It works by blocking the action of a certain natural substance in the body.

How should this medicine be used?

Promethazine comes as a tablet and syrup (liquid) to take by mouth and as a suppository to use rectally.When promethazine is used to treat allergies, it is usually taken one to four times daily, before meals and/or at bedtime. When promethazine is used to relieve cold symptoms, it is usually taken every 4-6 hours as needed. When promethazine is used to treat motion sickness, it is taken 30-60 minutes before travel and again after 8-12 hours if needed. On longer trips, promethazine is usually taken in the morning and before the evening meal on each day of travel. When promethazine is used to treat or prevent nausea and vomiting it is usually taken every 4-6 hours as needed. Promethazine may also be taken at bedtime the night before surgery to relieve anxiety and produce quiet sleep. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take promethazine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Promethazine suppositories are for rectal use only. Do not try to swallow the suppositories or insert in any other part of your body.

If you are taking promethazine liquid, do not use a household spoon to measure your dose. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.

To insert a promethazine suppository, follow these steps:

  • If the suppository feels soft, hold it under cold, running water for 1 minute. Remove the wrapper.
  • Dip the tip of the suppository in water.
  • Lie down on your left side and raise your right knee to your chest. (A left-handed person should lie on the right side and raise the left knee.)
  • Using your finger, insert the suppository into the rectum, about ½ to 1 inch in children who are 2 years of age older and 1 inch in adults. Hold it in place for a few moments.
  • Stand up after about 15 minutes. Wash your hands thoroughly and resume your normal activities.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking promethazine,

  • tell your doctor and pharmacist if you are allergic to promethazine, other phenothiazines (certain medications used to treat mental illness, nausea, vomiting, severe hiccups, and other conditions) or any other medications. Also tell your doctor and pharmacist if you have ever had an unusual or unexpected reaction when you took promethazine, another phenothiazine, or any other medication. Ask your doctor or pharmacist if you do not know if a medication you are allergic to is a phenothiazine.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants ('mood elevators') such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines; azathioprine (Imuran);barbiturates such as phenobarbital (Luminal); cancer chemotherapy; epinephrine (Epipen); ipratropium (Atrovent)medications for anxiety, irritable bowel disease, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems; monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and selegiline (Eldepryl, Emsam, Zelapar); narcotics and other pain medication; sedatives; sleeping pills;and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had an enlarged prostate (a male reproductive gland); glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision); seizures; ulcers; blockage in the passage between the stomach and intestine; blockage in the bladder; asthma or other lung disease; sleep apnea; cancer;any condition that affects the production of blood cells in your bone marrow; or heart or liver disease. If you will be giving promethazine to a child, also tell the child's doctor if the child has any of the following symptoms before he or she receives the medication: vomiting, listlessness, drowsiness, confusion, aggression, seizures, yellowing of the skin or eyes, weakness, or flu-like symptoms. Also tell the child's doctor if the child has not been drinking normally, has had excessive vomiting or diarrhea, or appears dehydrated.
  • tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking promethazine, call your doctor. Do not breastfeed while you are taking promethazine.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking promethazine.
  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. If you are giving promethazine to a child, watch the child to be sure he or she does not get hurt while riding a bike or participating in other activities that could be dangerous.
  • remember that alcohol can add to the drowsiness caused by this medication.
  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Promethazine may make your skin sensitive to sunlight.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Promethazine can cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dry mouth
  • drowsiness
  • listlessness
  • difficulty falling asleep or staying asleep
  • nightmares
  • dizziness
  • ringing in ears
  • blurred or double vision
  • loss of coordination
  • upset stomach
  • vomiting
  • nervousness
  • restlessness
  • hyperactivity
  • abnormally happy mood
  • stuffy nose
  • itching

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

  • wheezing
  • slowed breathing
  • breathing stops for a short time
  • fever
  • sweating
  • stiff muscles
  • decreased alertness
  • fast or irregular pulse or heartbeat
  • faintness
  • abnormal or uncontrollable movements
  • hallucinations (seeing things or hearing voices that do not exist)
  • confusion
  • overwhelming or unmanageable fear or emotion
  • seizures
  • uncontrollable shaking of a part of the body
  • unusual bruising or bleeding
  • sore throat, fever, chills, and other signs of infection
  • uncontrolled eye movements
  • tongue sticking out
  • abnormal neck position
  • inability to respond to people around you
  • yellowing of the skin or eyes
  • rash
  • hives
  • swelling of the face, eyes, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

Promethazine may cause other side effects. Call your doctor if you experience any unusual problems while you are taking this medication.

What storage conditions are needed for this medicine?

Keep this medication in the carton or container it came in, tightly closed, and out of reach of children. Store promethazine tablets and liquid at room temperature and away from excess heat and moisture (not in the bathroom). Store promethazine suppositories in the refrigerator. Protect the medication from light. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • difficulty breathing
  • slowed or stopped breathing
  • dizziness
  • lightheadedness
  • fainting
  • loss of consciousness
  • fast heartbeat
  • tight muscles that are difficult to move
  • loss of coordination
  • continuous twisting movements of the hands and feet
  • dry mouth
  • wide pupils (black circles in the middle of the eyes)
  • flushing
  • upset stomach
  • constipation
  • abnormal excitement or agitation
  • nightmares

What other information should I know?

Keep all appointments with your doctor.

Promethazine can interfere with the results of home pregnancy tests. Talk to your doctor if you think you might be pregnant while you are taking promethazine. Do not try to test for pregnancy at home.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking promethazine.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

  • Phenergan®
  • Promacot®
  • Promethegan®

Brand name(s) of combination products:

  • Prometh® VC Syrup (containing Promethazine Hydrochloride and Phenylephrine Hydrochloride)

Ask Our Patient Community about Phenergan

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Thank you for visiting Patientsville.com. We hope you found our information about prescription drug side effects helpful. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Thank you for visiting Patientsville.net. Hope you enjoyed finding Phenergan safety information and found answers to Your Questions about Phenergan side effects