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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
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Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Propylthiouracil Safety Reports submitted to FDA

Total Propylthiouracil reports: 9.
Propylthiouracil FDA safety alerts: No.
Reported deaths: 1    Reported hospitalizations: 8.
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FDA Reported Propylthiouracil Side Effects: goitre, blood thyroid stimulating hormone decreased, rash pruritic, blood albumin decreased, leukocytoclastic vasculitis, diarrhoea, arthralgia, anti-neutrophil cytoplasmic antibody positive vasculitis, abdominal pain lower, anaemia, vasculitis.
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Propylthiouracil Side Effects Report #5656237-7
Physician from JAPAN reported PROPYLTHIOURACIL problem on Feb 25, 2008. Female patient, 16 years of age, was diagnosed with basedow's disease and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, antineutrophil cytoplasmic antibody positive, antiphospholipid syndrome, arthralgia, cardiac murmur, coagulation factor xiii level decreased, deep vein thrombosis, glomerulonephritis, goitre. PROPYLTHIOURACIL dosage: unknown. Patient was hospitalized. Patient recovered.

Propylthiouracil Side Effects Report #5678710-8
PROPYLTHIOURACIL problem was reported by a Consumer or non-health professional from TAIWAN, PROVINCE OF CHINA on Mar 10, 2008. Female patient, 42 years of age, was diagnosed with hyperthyroidism and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: agranulocytosis, bone marrow failure, chills, cough, dysphagia, enterobacter bacteraemia, erythroid series abnormal, headache, hyperthyroidism. PROPYLTHIOURACIL dosage: 100 MG; TID;. Patient was hospitalized. Patient recovered.

Propylthiouracil Side Effects Report #5684475-6
Pharmacist from UNITED STATES reported PROPYLTHIOURACIL problem on Mar 27, 2008. Female patient, 19 years of age, was diagnosed with hyperthyroidism and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: abdominal pain, acute hepatic failure, blood pressure increased, brain herniation, convulsion, decreased appetite, mental status changes, nausea, neurological examination abnormal. PROPYLTHIOURACIL dosage: unknown. Patient died on 12/04/2007.

Propylthiouracil Side Effects Report #5635698-3
PROPYLTHIOURACIL problem was reported by a Consumer or non-health professional from TURKEY on Feb 11, 2008. Female patient, 43 years of age, was diagnosed with basedow's disease and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: blood albumin decreased, blood immunoglobulin e increased, blood ph increased, breath sounds abnormal, eosinophil percentage increased, haemoglobin decreased, neutrophil percentage decreased, no therapeutic response, percussion test abnormal. PROPYLTHIOURACIL dosage: unknown. Patient was hospitalized. Patient recovered.

Propylthiouracil Side Effects Report #5635700-9
Physician from JAPAN reported PROPYLTHIOURACIL problem on Feb 11, 2008. Female patient, 35 years of age, was diagnosed with hyperthyroidism and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: antineutrophil cytoplasmic antibody increased, antineutrophil cytoplasmic antibody positive, arthralgia, computerised tomogram abnormal, cough, dyspnoea, haematuria, heart rate increased. PROPYLTHIOURACIL dosage: 250 MG; PO. During the same period patient was treated with THIAMAZOLE. Patient was hospitalized. Patient recovered.

Propylthiouracil Side Effects Report #5593081-3
PROPYLTHIOURACIL problem was reported by a Consumer or non-health professional from SAUDI ARABIA on Jan 03, 2008. Female patient, child 8 years of age, was diagnosed with basedow's disease and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: acute hepatic failure, hepatic necrosis, hepatitis cholestatic, hepatotoxicity. PROPYLTHIOURACIL dosage: 50 MG; TID;. During the same period patient was treated with PROPRANOLOL. Patient was hospitalized. Patient recovered.

Propylthiouracil Side Effects Report #5593084-9
Physician from CHINA reported PROPYLTHIOURACIL problem on Jan 03, 2008. Female patient, 22 years of age, was diagnosed with hyperthyroidism and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: antineutrophil cytoplasmic antibody positive, body temperature increased, bronchoscopy abnormal, haemoglobin decreased, haemoptysis, vasculitis. PROPYLTHIOURACIL dosage: 100 MG; QD. Patient was hospitalized. Patient recovered.

Propylthiouracil Side Effects Report #5379374-3
PROPYLTHIOURACIL problem was reported by a Consumer or non-health professional from UNITED STATES on June 19, 2007. Female patient, 23 years of age, was diagnosed with basedow's disease and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: aortic valve incompetence, blood ph increased, blood thyroid stimulating hormone decreased, caesarean section, cardiac murmur, cardiomegaly, chest x-ray abnormal, ejection fraction decreased. PROPYLTHIOURACIL dosage: 100 MG;TID;PO. Patient was hospitalized. Patient recovered.

Propylthiouracil Side Effects Report #5379374-3
Consumer or non-health professional from UNITED STATES reported PROPYLTHIOURACIL problem on June 19, 2007. Female patient, 23 years of age, was diagnosed with basedow's disease and was treated with PROPYLTHIOURACIL. After drug was administered, patient experienced the following problems/side effects: aortic valve incompetence, blood ph increased, blood thyroid stimulating hormone decreased, caesarean section, cardiac murmur, cardiomegaly, chest x-ray abnormal, ejection fraction decreased. PROPYLTHIOURACIL dosage: 100 MG;TID;PO. Patient was hospitalized. Patient recovered.


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abdominal pain upper, antineutrophil cytoplasmic antibody positive, antiphospholipid syndrome, arthralgia, cardiac murmur, coagulation factor xiii level decreased, deep vein thrombosis, glomerulonephritis, goitre, , was diagnosed with basedow's disease and was diagnosed with hyperthyroidism and was diagnosed with hyperthyroidism and