PYRAZINAMIDE Side Effects

6595903-6 | C-reactive Protein Increased, Cytolytic Hepatitis, Eosinophilia, Hepatic Failure, Lymph Node Palpable, Oedema, Pruritus, Pyrexia
on Feb 22, 2010 Female patient from FRANCE , 25 years of age, was diagnosed with tuberculosis (What is tuberculosis?) and was treated with Pyrazinamide (View Usage). Patient experienced the following unwanted or unexpected effects: c-reactive protein increased, cytolytic hepatitis, eosinophilia, hepatic failure, lymph node palpable, oedema, pruritus, pyrexia. Pyrazinamide dosage: Dose Unit: 500 Mg. During the same period patient was treated with RIFAMPICIN (View Rifampicin Review and Rifampicin Label ), RIMIFON (Dose Unit: 225 Mg) (View Rimifon Review and Rimifon Label ). Patient was hospitalized.

6282559-5 | Abdominal Pain, Ammonia Increased, Coagulopathy, Encephalopathy, Hepatotoxicity, International Normalised Ratio Increased, Jaundice, Liver Function Test Abnormal, Liver Injury
Patient was taking Pyrazinamide (View Usage). Patient had the following side effects: abdominal pain (What is abdominal pain?), ammonia increased, coagulopathy, encephalopathy, hepatotoxicity, international normalised ratio increased, jaundice (What is jaundice?), liver function test abnormal, liver injury on Jul 22, 2009 from UNITED STATES Additional patient health information: Female patient , 40 years of age, . Pyrazinamide dosage: . During the same period patient was treated with RIFAMPICIN (View Rifampicin Review and Rifampicin Label ), ISONIAZID (View Isoniazid Review and Isoniazid Label ), ADVIL (View Advil Review and Advil Label ), TYLENOL (CAPLET) (View Tylenol (caplet) Review and Tylenol (caplet) Label ), IV FLUIDS NORMAL SALINE (View Iv Fluids Normal Saline Review and Iv Fluids Normal Saline Label ), ZOFRAN (View Zofran Review and Zofran Label ), MORPHINE (View Morphine Review and Morphine Label ), FRESH FROZEN PLASMA (View Fresh Frozen Plasma Review and Fresh Frozen Plasma Label ).

6282559-5 | Abdominal Pain, Ammonia Increased, Coagulopathy, Encephalopathy, Hepatotoxicity, International Normalised Ratio Increased, Jaundice, Liver Function Test Abnormal, Liver Injury
Adverse event was reported on Jul 22, 2009 by a Female patient taking Pyrazinamide (View Usage) (Dosage: ) . Location: UNITED STATES , 40 years of age, After Pyrazinamide was administered, patient had the following side effects: abdominal pain (What is abdominal pain?), ammonia increased, coagulopathy, encephalopathy, hepatotoxicity, international normalised ratio increased, jaundice (What is jaundice?), liver function test abnormal, liver injury. During the same period patient was treated with RIFAMPICIN (View Rifampicin Review and Rifampicin Label ), ISONIAZID (View Isoniazid Review and Isoniazid Label ), ADVIL (View Advil Review and Advil Label ), TYLENOL (CAPLET) (View Tylenol (caplet) Review and Tylenol (caplet) Label ), IV FLUIDS NORMAL SALINE (View Iv Fluids Normal Saline Review and Iv Fluids Normal Saline Label ), ZOFRAN (View Zofran Review and Zofran Label ), MORPHINE (View Morphine Review and Morphine Label ), FRESH FROZEN PLASMA (View Fresh Frozen Plasma Review and Fresh Frozen Plasma Label ).

6148536-X | Pruritus, Rash Erythematous
on Apr 06, 2009 Female patient from UNITED STATES , 45 years of age, weighting 140.0 lb, was diagnosed with tuberculosis (What is tuberculosis?) and was treated with Pyrazinamide (View Usage). Patient experienced the following unwanted or unexpected effects: pruritus, rash erythematous. Pyrazinamide dosage: 1500 Mg Daily Po 7 Doses. Patient was hospitalized.


5386408-9 | Gout
on Jul 10, 2007 Male patient from UNITED STATES , 35 years of age, weighting 209.0 lb, was diagnosed with tuberculosis (What is tuberculosis?) and was treated with Pyrazinamide (View Usage). Patient had the following side effects: gout (What is gout?). Pyrazinamide dosage: 4000 Mg Daily Po.

5314197-2 | Hyperuricaemia, Lactic Acidosis, Pancreatitis Acute, Sepsis
Patient was taking Pyrazinamide (View Usage). After Pyrazinamide was administered, patient had the following side effects: hyperuricaemia, lactic acidosis, pancreatitis acute, sepsis (What is sepsis?) on Apr 13, 2007 from SPAIN Additional patient health information: Female patient , 91 years of age, was diagnosed with bone tuberculosis and. Pyrazinamide dosage: See Image. During the same period patient was treated with ISONIAZID (See Image) (View Isoniazid Review and Isoniazid Label ), RIFAMPICIN (600 Mg, Qd) (View Rifampicin Review and Rifampicin Label ), PYRIDOXINE (PYRIDOXINE) (View Pyridoxine (pyridoxine) Review and Pyridoxine (pyridoxine) Label ). Patient was hospitalized.

5305594-X | Hyperuricaemia, Lactic Acidosis, Pancreatitis Acute, Sepsis
Adverse event was reported on Apr 03, 2007 by a Female patient taking Pyrazinamide (View Usage) (Dosage: 1500 Mg) was diagnosed with bone tuberculosis and. Location: SPAIN , 91 years of age, Patient experienced the following unwanted or unexpected effects: hyperuricaemia, lactic acidosis, pancreatitis acute, sepsis (What is sepsis?). During the same period patient was treated with ISONIAZID (250 Mg, Qd) (View Isoniazid Review and Isoniazid Label ), RIFAMPICIN (600 Mg, Qd) (View Rifampicin Review and Rifampicin Label ), PYRIDOXINE (PYRIDOXINE) (View Pyridoxine (pyridoxine) Review and Pyridoxine (pyridoxine) Label ). Patient was hospitalized.

5071416-8 | Abdominal Pain Upper, Alanine Aminotransferase Increased, Arthralgia, Aspartate Aminotransferase Increased, Blood Bilirubin Increased, Fatigue, Hepatic Trauma, Hepatotoxicity
on Aug 03, 2006 Female patient from UNITED STATES , 40 years of age, was treated with Pyrazinamide (View Usage). Patient had the following side effects: abdominal pain upper, alanine aminotransferase increased, arthralgia, aspartate aminotransferase increased, blood bilirubin increased, fatigue, hepatic trauma, hepatotoxicity. Pyrazinamide dosage: . During the same period patient was treated with INH (View Inh Review and Inh Label ), RIFAMPIN (View Rifampin Review and Rifampin Label ), ETHAMBUTOL HYDROCHLORIDE (View Ethambutol Hydrochloride Review and Ethambutol Hydrochloride Label ), AVELOX (View Avelox Review and Avelox Label ), LEVAQUIN (View Levaquin Review and Levaquin Label ), CIPRO (View Cipro Review and Cipro Label ).

5060097-5 | Ascites, Hepatic Atrophy, Hepatic Encephalopathy, Hepatic Necrosis, Hepatitis, Liver Transplant, Renal Failure
on May 10, 2006 Male patient from SPAIN , 39 years of age, was diagnosed with tuberculosis (What is tuberculosis?) and was treated with Pyrazinamide (View Usage). After Pyrazinamide was administered, patient had the following side effects: ascites, hepatic atrophy, hepatic encephalopathy, hepatic necrosis, hepatitis (What is hepatitis?), liver transplant (What is liver transplant?), renal failure. Pyrazinamide dosage: 1800 Mg/day. During the same period patient was treated with ISONIAZID (300mg/day) (View Isoniazid Review and Isoniazid Label ), RIFAMPIN (View Rifampin Review and Rifampin Label ), STREPTOMYCIN (View Streptomycin Review and Streptomycin Label ), CIPROFLOXACIN (View Ciprofloxacin Review and Ciprofloxacin Label ), ETHAMBUTOL HCL (View Ethambutol Hcl Review and Ethambutol Hcl Label ), TRAMADOL HCL (View Tramadol Hcl Review and Tramadol Hcl Label ). Patient was hospitalized.

5005674-2 | Ascites, Bone Tuberculosis, Coagulopathy, Cytolytic Hepatitis, Fistula, Hepatic Atrophy, Hepatic Encephalopathy, Hepatic Failure, Hepatic Necrosis
Patient was taking Pyrazinamide (View Usage). Patient experienced the following unwanted or unexpected effects: ascites, bone tuberculosis, coagulopathy, cytolytic hepatitis, fistula (What is fistula?), hepatic atrophy, hepatic encephalopathy, hepatic failure, hepatic necrosis on May 10, 2006 from Additional patient health information: Male patient , 39 years of age, was diagnosed with tuberculosis (What is tuberculosis?) and. Pyrazinamide dosage: 1800mg/day. During the same period patient was treated with ISONIAZID (300mg/day) (View Isoniazid Review and Isoniazid Label ), RIFAMPIN (View Rifampin Review and Rifampin Label ), STREPTOMYCIN (View Streptomycin Review and Streptomycin Label ), CIPROFLOXACIN (View Ciprofloxacin Review and Ciprofloxacin Label ), ETHAMBUTOL (View Ethambutol Review and Ethambutol Label ), TRAMADOL HCL (View Tramadol Hcl Review and Tramadol Hcl Label ). Patient was hospitalized.

4823229-7 | Anorexia, Autoimmune Hepatitis, Eosinophil Percentage Increased, International Normalised Ratio Increased, Palpitations, Thyroiditis
Adverse event was reported on Oct 24, 2005 by a Male patient taking Pyrazinamide (View Usage) (Dosage: ) was diagnosed with prophylaxis and. Location: UNITED STATES , 25 years of age, Patient had the following side effects: anorexia, autoimmune hepatitis, eosinophil percentage increased, international normalised ratio increased, palpitations, thyroiditis. During the same period patient was treated with RIFAMPICIN (View Rifampicin Review and Rifampicin Label ).

4698454-9 | Abdominal Pain Upper, Alanine Aminotransferase Increased, Anorexia, Antinuclear Antibody Positive, Aspartate Aminotransferase Increased, Eosinophil Percentage Increased, Fatigue, Flank Pain, Increased Appetite
on May 11, 2005 Male patient from , 25 years of age, was diagnosed with tuberculosis prophylaxis and was treated with Pyrazinamide (View Usage). After Pyrazinamide was administered, patient had the following side effects: abdominal pain upper, alanine aminotransferase increased, anorexia, antinuclear antibody positive, aspartate aminotransferase increased, eosinophil percentage increased, fatigue, flank pain, increased appetite. Pyrazinamide dosage: . During the same period patient was treated with RIFAMPIN (View Rifampin Review and Rifampin Label ). Patient was hospitalized.

4695655-0 | Cholestasis, Cytolytic Hepatitis, Dermatitis Allergic, Eosinophilia, Hepatic Failure, Liver Disorder, Pyrexia, Skin Exfoliation
on Jun 08, 2005 Female patient from , 75 years of age, was diagnosed with bone tuberculosis and was treated with Pyrazinamide (View Usage). Patient experienced the following unwanted or unexpected effects: cholestasis, cytolytic hepatitis, dermatitis allergic, eosinophilia, hepatic failure, liver disorder, pyrexia, skin exfoliation. Pyrazinamide dosage: . During the same period patient was treated with RIFADIN (View Rifadin Review and Rifadin Label ), RIMIFON (View Rimifon Review and Rimifon Label ), AUGMENTIN '125' (View Augmentin '125' Review and Augmentin '125' Label ), OFLOCET (View Oflocet Review and Oflocet Label ), ROCEPHIN (View Rocephin Review and Rocephin Label ), RULID (View Rulid Review and Rulid Label ), ORELOX (View Orelox Review and Orelox Label ), TAVANIC (View Tavanic Review and Tavanic Label ). Patient was hospitalized.

4671128-6 | Ascites, Dizziness, Encephalopathy, Eosinophilia, Hepatic Necrosis, Hepatomegaly, Hyperpyrexia, Hypoacusis
Patient was taking Pyrazinamide (View Usage). Patient had the following side effects: ascites, dizziness (What is dizziness?), encephalopathy, eosinophilia, hepatic necrosis, hepatomegaly, hyperpyrexia, hypoacusis on May 11, 2005 from Additional patient health information: Female patient , 28 years of age, weighting 110.2 lb, was diagnosed with tuberculosis (What is tuberculosis?) and. Pyrazinamide dosage: 1500 Mg Daily. During the same period patient was treated with CIPROFLOXACIN HCL (500 Mg Twice Daily) (View Ciprofloxacin Hcl Review and Ciprofloxacin Hcl Label ), ISONIOZID (View Isoniozid Review and Isoniozid Label ), RIFAMPIN (View Rifampin Review and Rifampin Label ), ETHAMBUTOL HCL (View Ethambutol Hcl Review and Ethambutol Hcl Label ). Patient was hospitalized.

4670297-1 | Abdominal Pain Upper, Abdominal Tenderness, Anorexia, Anti-thyroid Antibody Positive, Antinuclear Antibody Positive, Autoimmune Hepatitis, Blood Thyroid Stimulating Hormone Decreased, Eosinophil Count Increased, Fatigue
Adverse event was reported on May 11, 2005 by a Male patient taking Pyrazinamide (View Usage) (Dosage: ) was diagnosed with tuberculosis prophylaxis and. Location: , 25 years of age, After Pyrazinamide was administered, patient had the following side effects: abdominal pain upper, abdominal tenderness, anorexia, anti-thyroid antibody positive, antinuclear antibody positive, autoimmune hepatitis, blood thyroid stimulating hormone decreased, eosinophil count increased, fatigue. During the same period patient was treated with RIFAMPIN (View Rifampin Review and Rifampin Label ). Patient was hospitalized.

4597025-2 | Abdominal Pain Upper, Autoimmune Hepatitis, Blood Thyroid Stimulating Hormone Decreased, Flank Pain, International Normalised Ratio Increased, Thyroiditis, Thyroxine Decreased
on Feb 17, 2005 Male patient from , 25 years of age, was diagnosed with prophylaxis and was treated with Pyrazinamide (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain upper, autoimmune hepatitis, blood thyroid stimulating hormone decreased, flank pain, international normalised ratio increased, thyroiditis, thyroxine decreased. Pyrazinamide dosage: . During the same period patient was treated with RIFAMPICIN (View Rifampicin Review and Rifampicin Label ).

4593938-6 | Antinuclear Antibody Positive, Autoimmune Hepatitis, Flank Pain, International Normalised Ratio Increased, Pyrexia, Smooth Muscle Antibody Positive, Thyroiditis
on Feb 17, 2005 Male patient from , 25 years of age, was diagnosed with prophylaxis and was treated with Pyrazinamide (View Usage). Patient had the following side effects: antinuclear antibody positive, autoimmune hepatitis, flank pain, international normalised ratio increased, pyrexia, smooth muscle antibody positive, thyroiditis. Pyrazinamide dosage: . During the same period patient was treated with RIFAMPICIN (View Rifampicin Review and Rifampicin Label ).

4590983-1 | Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Hepatic Failure, Hyperbilirubinaemia
Patient was taking Pyrazinamide (View Usage). After Pyrazinamide was administered, patient had the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic failure, hyperbilirubinaemia on Feb 22, 2005 from Additional patient health information: Female patient , 81 years of age, was diagnosed with tuberculosis (What is tuberculosis?) and. Pyrazinamide dosage: 1500 Mg Daily Oral. During the same period patient was treated with RIFAMPIN (600 Mg Daily Oral) (View Rifampin Review and Rifampin Label ), SPIRONOLACTONE (View Spironolactone Review and Spironolactone Label ), VIT B6 (View Vit B6 Review and Vit B6 Label ), VIT K (View Vit K Review and Vit K Label ), FLAGYL (View Flagyl Review and Flagyl Label ), LEVQUIN (View Levquin Review and Levquin Label ). Patient was hospitalized.

4590973-9 | Alpha Haemolytic Streptococcal Infection, Bacterial Culture Positive, Beta Haemolytic Streptococcal Infection, Chest Pain, Lung Neoplasm, Moraxella Infection, Pneumonitis
Adverse event was reported on Feb 22, 2005 by a Male patient taking Pyrazinamide (View Usage) (Dosage: 21 Mg/m2 /hr X 6 Hrs) was diagnosed with neuroblastoma (What is neuroblastoma?) and. Location: , weighting 44.75 lb, Patient experienced the following unwanted or unexpected effects: alpha haemolytic streptococcal infection, bacterial culture positive, beta haemolytic streptococcal infection, chest pain (What is chest pain?), lung neoplasm, moraxella infection, pneumonitis.