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Ramipril Side Effects

Common Ramipril Side Effects


The most commonly reported Ramipril side effects (click to view or check a box to report):

Renal Failure Acute (252)
Dyspnoea (156)
Angioedema (149)
Hypotension (147)
Dizziness (128)
Cough (113)
Dehydration (105)
Hyperkalaemia (104)
Nausea (102)
Hyponatraemia (97)
Diarrhoea (94)
Confusional State (91)
Vomiting (87)
Syncope (87)
Malaise (84)
Fall (82)
Chest Pain (78)
Fatigue (77)
Headache (75)
Asthenia (72)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Ramipril Side Effects Reported to FDA

The following Ramipril reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Ramipril on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Oropharyngeal Swelling
This is a report of a 73-year-old female patient (weight: NA) from IT, suffering from the following symptoms/conditions: hypertension, who was treated with Ramipril (dosage: 1.25 Mg Daily, start time: Aug 01, 2013), combined with:
  • Coumadin
  • Congescor
  • Humalog
  • Torvast
  • Lasix
  • Diamox
and developed a serious reaction and side effect(s). The consumer presented with:
  • Oropharyngeal Swelling
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Ramipril treatment in female patients, resulting in oropharyngeal swelling side effect.

Tooth Abscess, Nausea
This report suggests a potential Ramipril Tooth Abscess, Nausea side effect(s) that can have serious consequences. A 54-year-old female patient (weight: NA) from CA was diagnosed with the following symptoms/conditions: NA and used Ramipril (dosage: 5 Mg, Unk) starting Jan 21, 2014. Soon after starting Ramipril the patient began experiencing various side effects, including:
  • Tooth Abscess
  • Nausea
Drugs used concurrently:
  • Aubagio (14 Mg, Unk)
  • Synthroid (0.125 Mg, Unk)
Although Ramipril demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as tooth abscess, may still occur.

Musculoskeletal Stiffness, Myalgia
This Musculoskeletal Stiffness, Myalgia problem was reported by a consumer or non-health professional from GB. A 66-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension. On NS this consumer started treatment with Ramipril (dosage: NA). The following drugs were being taken at the same time: NA. When commencing Ramipril, the patient experienced the following unwanted symptoms/side effects:
  • Musculoskeletal Stiffness
  • Myalgia
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as musculoskeletal stiffness, may become evident only after a product is in use by the general population.

Gingival Swelling, Tooth Disorder, Gingival Pain
This is a report of a 69-year-old male patient (weight: NA) from GB. The patient developed the following symptoms/conditions: NA and was treated with Ramipril (ramipril) (dosage: NA) starting Oct 29, 2013. Concurrently used drugs:
  • Co-codamol (panadeine Co)
  • Diclofenac Sodium (diclofenac Sodium)
  • Losartan (losartan)
  • Omeprazole (omperazole)
Soon after that, the consumer experienced the following side effects:
  • Gingival Swelling
  • Tooth Disorder
  • Gingival Pain
This opens a possibility that Ramipril (ramipril) treatment could cause the above reactions, including gingival swelling, and some male subjects may be more susceptible.


Cough, Wheezing, Impaired Work Ability
A 53-year-old female patient (weight: NA) from GB with the following symptoms/conditions: hypertension started Ramipril treatment (dosage: NA) on NS. Soon after starting Ramipril treatment, the subject experienced various side effects, including:
  • Cough
  • Wheezing
  • Impaired Work Ability
Concurrently used drugs:
  • Citalopram (citalopram)
This finding indicates that some female patients could be more vulnerable to Ramipril.

Chest Pain
A 41-year-old female patient from GB (weight: NA) experienced symptoms, such as: hypertension and was treated with Ramipril (ramipril)(dosage: NA). The treatment was initiated on Oct 24, 2013. After that a consumer reported the following side effect(s):
  • Chest Pain
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Ramipril (ramipril) efficacy:
  • Sertraline Hydrochloride (sertraline Hydrochloride)


Feeling Abnormal, Urinary Retention, Blood Pressure Increased, Blood Cholesterol Increased, Nervousness, Therapeutic Response Unexpected
In this report, Ramipril was administered for the following condition: hypertension.A 61-year-old male consumer from US (weight: NA) started Ramipril treatment (dosage: NA) on 2006.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Feeling Abnormal
  • Urinary Retention
  • Blood Pressure Increased
  • Blood Cholesterol Increased
  • Nervousness
  • Therapeutic Response Unexpected
A possible interaction with other drugs could have contributed to this reaction:
  • Altace
  • Aspirin
Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Ramipril treatment could be related to the listed above side effect(s).

Lactic Acidosis, Renal Failure Acute
This is a report of the following Ramipril side effect(s):
  • Lactic Acidosis
  • Renal Failure Acute
A 71-year-old female patient from FR (weight: NA) presented with the following condition: NA and received a treatment with Ramipril (dosage: 1.25 Mg, Daily) starting: NS.The following concurrently used drugs could have generated interactions:
  • Lasilix (1.5 Df, Daily)
  • Lodoz (1 Df, Daily)
  • Glucophage (1 Df, 3x/day)
  • Januvia
  • Cordarone
  • Levothyrox (Unk)
  • Spiriva
  • Cysteine/methionine
This report suggests that a Ramipril treatment could be associated with the listed above side effect(s).

Treatment Failure, Hypertension
This Ramipril report was submitted by a 44-year-old male consumer from IT (weight: NA). The patient was diagnosed with: hypertension and Ramipril was administered (dosage: 1 D) starting: Nov 01, 2013. The consumer developed a set of symptoms:
  • Treatment Failure
  • Hypertension
Other drugs used simultaneously:
  • Norvasc (1 D)
Those unexpected symptoms could be linked to a Ramipril treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Wheezing, Cough
This is a report of a possible correlation between Ramipril use and the following symptoms/side effect(s):
  • Wheezing
  • Cough
which could contribute to an assessment of Ramipril risk profile.A 53-year-old female consumer from GB (weight: NA) was suffering from hypertension and was treated with Ramipril (dosage: 5 Mg) starting NS.Other concurrent medications:
  • Citalopram


Swelling Face, Swollen Tongue, Local Swelling, C-reactive Protein Increased
A 83-year-old female patient from IT (weight: NA) presented with the following symptoms: hypertension and after a treatment with Ramipril (dosage: 5 Mg (5 Mg, 1 In 1d), Oral) experienced the following side effect(s):
  • Swelling Face
  • Swollen Tongue
  • Local Swelling
  • C-reactive Protein Increased
The treatment was started on NS. Ramipril was used in combination with the following drugs:
  • Lobidiur (nebicard-h)
  • Cardioaspirin (acetylsalicylic Acid)
  • Microser (betahistine Hydrochloride)
This report could alert potential Ramipril consumers.

Nausea, Tooth Abscess
In this report, a 54-year-old female patient from CA (weight: NA) was affected by a possible Ramipril side effect.The patient was diagnosed with NA. After a treatment with Ramipril (dosage: NA, start date: Jan 21, 2014), the patient experienced the following side effect(s):
  • Nausea
  • Tooth Abscess
The following simultaneously used drugs could have led to this reaction:
  • Aubagio
  • Synthroid
The findings here stress that side effects should be taken into consideration when evaluating a Ramipril treatment.

Gingival Swelling, Tooth Disorder, Gingival Pain
This is a report of a 69-year-old male patient from GB (weight: NA), who used Ramipril (dosage: Unk) for a treatment of NA. After starting a treatment on Feb 18, 2014, the patient experienced the following side effect(s):
  • Gingival Swelling
  • Tooth Disorder
  • Gingival Pain
The following drugs could possibly have interacted with the Ramipril treatment
  • Co-codamol (Unk)
  • Diclofenac Sodium (Unk)
  • Omeprazole (Unk)
  • Losartan (Unk)
Taken together, these observations suggest that a Ramipril treatment could be related to side effect(s), such as Gingival Swelling, Tooth Disorder, Gingival Pain.

Oligohydramnios, Diabetes Mellitus, Premature Rupture Of Membranes, Vomiting
This oligohydramnios side effect was reported by a physician from DE. A 32-year-old female patient (weight:NA) experienced the following symptoms/conditions: hypertension. The patient was prescribed Ramipril (dosage: 5 Mg, 1x/day), which was started on Jun 07, 2012. Concurrently used drugs:
  • Edarbi (20 Mg, 1x/day)
  • Edarbi (20 Mg, 1x/day)
  • Methyldopa (250 Mg, 3x/day)
  • Influsplit Ssw (Unk)
  • Folio Forte (0.8 Mg, 1x/day)
When starting to take Ramipril the consumer reported the following symptoms:
  • Oligohydramnios
  • Diabetes Mellitus
  • Premature Rupture Of Membranes
  • Vomiting
These side effects may potentially be related to Ramipril.

Angioedema, Hypersensitivity
This is a Ramipril side effect report of a 71-year-old male patient (weight:NA) from US, suffering from the following symptoms/conditions: hypertension, who was treated with Ramipril (dosage:1x Daily, start time: Mar 01, 2004), combined with: NA., and developed a serious reaction and a angioedema side effect. The patient presented with:
  • Angioedema
  • Hypersensitivity
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Ramipril treatment in male patients suffering from hypertension, resulting in angioedema.

Wheezing, Cough
This report suggests a potential Ramipril wheezing side effect(s) that can have serious consequences. A 53-year-old female patient from GB (weight:NA) was diagnosed with the following health condition(s): hypertension and used Ramipril (dosage: 5 Mg, Unk) starting NS. Soon after starting Ramipril the patient began experiencing various side effects, including:
  • Wheezing
  • Cough
Drugs used concurrently:
  • Citalopram (Unk)
Although Ramipril demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as wheezing, may still occur.

Confusional State, Hyponatraemia
This confusional state problem was reported by a health professional from FR. A 81-year-old male patient (weight: NA) was diagnosed with the following medical condition(s): arrhythmia.On NS a consumer started treatment with Ramipril (dosage: NA). The following drugs/medications were being taken at the same time:
  • Atacand (candesartan Cilexetil)
  • Amiodarone (amiodarone)
  • Temerit (nebeviolol Hydrochloride)
When commencing Ramipril, the patient experienced the following unwanted symptoms /side effects:
  • Confusional State
  • Hyponatraemia
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as confusional state, may become evident only after a product is in use by the general population.

Loss Of Consciousness, Paraesthesia, Presyncope, Dizziness
This is a Ramipril side effect report of a 48-year-old male patient (weight: NA) from IT. The patient developed the following symptoms/conditions: hypertension,dyslipidaemia,diabetes mellitus and was treated with Ramipril (dosage: NA) starting Jan 01, 2013. Concurrently used drugs:
  • Crestor
  • Gliclazide
Soon after that, the consumer experienced the following of symptoms:
  • Loss Of Consciousness
  • Paraesthesia
  • Presyncope
  • Dizziness
This opens a possibility that Ramipril could cause loss of consciousness and that some male patients may be more susceptible.

Bronchospasm, Urticaria
A 57-year-old female patient (weight: NA) from IT with the following symptoms: hypertension,asthma started Ramipril treatment (dosage: NA) on Jan 01, 1994. Soon after starting Ramipril treatment, the consumer experienced several side effects, including:
  • Bronchospasm
  • Urticaria
. Concurrently used drugs:
  • Aliflus Diskus
  • Barnidipine Hydrochloride
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Ramipril side effects, such as bronchospasm.

Angioedema, Respiratory Failure, Anaemia, Urinary Tract Infection
This angioedema side effect was reported by a physician from IT. A 70-year-old female patient (weight:NA) experienced the following symptoms/conditions: hypertension.The patient was prescribed Ramipril (dosage: NA), which was started on Dec 14, 2013. Concurrently used drugs: NA..When starting to take Ramipril the consumer reported symptoms, such as:
  • Angioedema
  • Respiratory Failure
  • Anaemia
  • Urinary Tract Infection
These side effects may potentially be related to Ramipril. The patient was hospitalized.

Lactic Acidosis, Renal Failure Acute
This is a report of a 71-year-old female patient (weight: NA) from FR, suffering from the following symptoms/conditions: NA, who was treated with Ramipril (dosage: NA, start time: NS), combined with:
  • Lasilix (Scored Tablet)
  • Lodoz (Strength:10mg/6.25 Mg)
  • Glucophage (Strength: 850 Mg)
  • Januvia
  • Cordarone
  • Levothyrox
  • Spiriva
  • Cysteine/methionine
and developed a serious reaction and side effect(s). The consumer presented with:
  • Lactic Acidosis
  • Renal Failure Acute
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Ramipril treatment in female patients, resulting in lactic acidosis side effect.

Syncope, Dizziness, Loss Of Consciousness
This report suggests a potential Ramipril Syncope, Dizziness, Loss Of Consciousness side effect(s) that can have serious consequences. A 77-year-old female patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: hypertension and used Ramipril (dosage: 2.5 Milligram Daily;) starting Feb 03, 2014. Soon after starting Ramipril the patient began experiencing various side effects, including:
  • Syncope
  • Dizziness
  • Loss Of Consciousness
Drugs used concurrently:
  • Alverine Citrate
  • Bendroflumethiazide
  • Fultium (Fultium-d3)
Although Ramipril demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as syncope, may still occur.

Oligohydramnios, Vomiting, Diabetes Mellitus, Premature Rupture Of Membranes, Obstructed Labour, Caesarean Section, Exposure During Pregnancy
This Oligohydramnios, Vomiting, Diabetes Mellitus, Premature Rupture Of Membranes, Obstructed Labour, Caesarean Section, Exposure During Pregnancy problem was reported by a physician from DE. A 32-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension. On Jun 07, 2012 this consumer started treatment with Ramipril (dosage: NA). The following drugs were being taken at the same time:
  • Edarbi
  • Edarbi
  • Methyldopa
  • Influsplit Ssw
  • Folio Forte
When commencing Ramipril, the patient experienced the following unwanted symptoms/side effects:
  • Oligohydramnios
  • Vomiting
  • Diabetes Mellitus
  • Premature Rupture Of Membranes
  • Obstructed Labour
  • Caesarean Section
  • Exposure During Pregnancy
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as oligohydramnios, may become evident only after a product is in use by the general population.

Foetal Heart Rate Deceleration Abnormality, Foetal Exposure During Pregnancy
This is a report of a female patient (weight: NA) from DE. The patient developed the following symptoms/conditions: NA and was treated with Ramipril (dosage: NA) starting Jun 07, 2012. Concurrently used drugs:
  • Edarbi
  • Edarbi
  • Methyldopa
  • Influsplit Ssw
  • Folio Forte
Soon after that, the consumer experienced the following side effects:
  • Foetal Heart Rate Deceleration Abnormality
  • Foetal Exposure During Pregnancy
This opens a possibility that Ramipril treatment could cause the above reactions, including foetal heart rate deceleration abnormality, and some female subjects may be more susceptible.

Back Pain, Neck Pain, Pain In Extremity, Hypoaesthesia
A 78-year-old male patient (weight: NA) from GB with the following symptoms/conditions: hypertension started Ramipril treatment (dosage: 1.25mg Qd) on Jan 29, 2014. Soon after starting Ramipril treatment, the subject experienced various side effects, including:
  • Back Pain
  • Neck Pain
  • Pain In Extremity
  • Hypoaesthesia
Concurrently used drugs:
  • Amlodipine
  • Aspirin
  • Atorvastatin
  • Lansoprazole
  • Seretide
  • Sildenafil (50mg)
This finding indicates that some male patients could be more vulnerable to Ramipril.

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Top 10 Ramipril Side Effects for Women

Women Side EffectsReports
Renal Failure Acute 118
Nausea 71
Dyspnoea 68
Dizziness 66
Hyponatraemia 61
Angioedema 60
Cough 59
Hypotension 57
Vomiting 56
Headache 50

Top 10 Ramipril Side Effects for Men

Men Side EffectsReports
Renal Failure Acute 134
Dyspnoea 88
Hypotension 88
Angioedema 87
Dehydration 69
Dizziness 62
Hyperkalaemia 58
Confusional State 55
Cough 54
Diarrhoea 50

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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