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Rasagiline Side Effects

Common Rasagiline Side Effects

The most commonly reported Rasagiline side effects (click to view or check a box to report):

Anaemia (4)
Oedema Peripheral (4)
Asthenia (4)
Serotonin Syndrome (3)
Squamous Cell Carcinoma (2)
Neuroleptic Malignant Syndrome (2)
Confusional State (2)
Aggression (2)
Blood Creatine Phosphokinase Increased (1)
Suicidal Ideation (1)
Blood Pressure Inadequately Controlled (1)
Cognitive Disorder (1)
Tardive Dyskinesia (1)
Laryngeal Cancer (1)
Activities Of Daily Living Impaired (1)
Hallucination, Visual (1)
Convulsion (1)
Death (1)
Delusion (1)
Apathy (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Rasagiline Side Effects Reported to FDA

The following Rasagiline reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Rasagiline on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Serotonin Syndrome
on Sep 05, 2013 Female from ES , 66 years of age, was diagnosed with and was treated with Rasagiline. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: serotonin syndrome. Rasagiline dosage: 1 Mg/day.
Associated medications used:
  • Stalevo (2 X 150 Tablets/day)
  • Stalevo (4 X 200 Tablets/day)
  • Carbidopa + Levodopa (Tablet At Night)
  • Amantadine (2 X 100mg Tablets/day)
  • Duloxetine (90 Mg/day)


Papillary Thyroid Cancer
Patient was taking Rasagiline Mesylate. Patient felt the following Rasagiline side effects: papillary thyroid cancer on Sep 13, 2012 from IL Additional patient health information: Female , 58 years of age, was diagnosed with and. Rasagiline Mesylate dosage: 1 Milligram Daily; Ol Phase. Patient was hospitalized.

Parkinson^s Disease
Adverse event was reported on Nov 07, 2012 by a Male taking Rasagiline Mesilate (Dosage: N/A) was diagnosed with and. Location: CN , 56 years of age, weighting 178.6 lb, After Rasagiline was administered, patient encountered several Rasagiline side effects: parkinson^s disease.
Multiple concurrent drugs taken:
  • Madopar (1st Dose)
  • Sinemet (1st Dose)
  • Sinemet (2nd Dose)
  • Sinemet (3rd Dose)
  • Sinemet (1st Dose)
  • Entacapone (200 Milligram Daily;)
  • Piribedil Sustained Release Tablets (150 Milligram Daily;)
Patient was hospitalized.

Parkinson's Disease
on May 23, 2012 Male from CHINA , weighting 178.6 lb, was diagnosed with and was treated with Rasagiline Mesylate. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: parkinson's disease. Rasagiline Mesylate dosage: N/A.
Associated medications used:
  • Sinemet (1st Dose)
  • Sinemet (3rd Dose)
  • Sinemet (1st Dose)
  • Entacapone (200 Milligram;)
  • Piribedil Sustained Release Tablets (150 Milligram;)
  • Madopar (1st Dose)
  • Sinemet (2nd Dose)
Patient was hospitalized.


Pharyngeal Cancer
on Apr 25, 2013 Male from AR , 62 years of age, weighting 165.3 lb, was diagnosed with and was treated with Rasagiline Mesilate. Patient felt the following Rasagiline side effects: pharyngeal cancer. Rasagiline Mesilate dosage: 1 Milligram Daily; Ol- Adagio Fu, 1mg/day.

Jealous Delusion, Marital Problem
Patient was taking Rasagiline. After Rasagiline was administered, patient encountered several Rasagiline side effects: jealous delusion, marital problem on May 02, 2012 from SPAIN Additional patient health information: Male , 61 years of age, was diagnosed with and. Rasagiline dosage: 1 Mg.
Multiple concurrent drugs taken:
  • Pramipexole Dihydrochloride (2.1 Mg)


Laryngeal Cancer
Adverse event was reported on Feb 13, 2012 by a Male taking Rasagiline Mesylate (Dosage: 1 Milligram; Ol- Adagio Fu, 1mg/day) was diagnosed with and. Location: ARGENTINA , weighting 165.3 lb, Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: laryngeal cancer.
Associated medications used:
  • Carbidopa + Levodopa (100/25 Bid)


Serotonin Syndrome, Neuroleptic Malignant Syndrome
on Feb 07, 2012 Male from DENMARK , 81 years of age, was diagnosed with and was treated with Rasagiline. Patient felt the following Rasagiline side effects: serotonin syndrome, neuroleptic malignant syndrome. Rasagiline dosage: N/A.
Multiple prescriptions taken:
  • Finasteride (finasteride)(finasteride)
  • Omeprazole
  • Stalevo (stalevo) (stalevo)
  • Dalteparin (dalteparin) (dalteparin)
  • Calcium W/colecalciferol(calcium, Colecalciferol)(calcium, Colecalcife
  • Alendronic Acid (alendronic Acid)(alendronic Acid)
  • Citalopram Hydrobromide
  • Midodrine (midodrine) (midodrine)
Patient was hospitalized.

Quality Of Life Decreased, Confusional State, Cognitive Disorder, Activities Of Daily Living Impaired, Apathy
on Jan 31, 2012 Male from BRAZIL , 72 years of age, was treated with Rasagiline. After Rasagiline was administered, patient encountered several Rasagiline side effects: quality of life decreased, confusional state, cognitive disorder, activities of daily living impaired, apathy. Rasagiline dosage: N/A.
Multiple concurrent drugs taken:
  • Domperidone (30 Mg/daily)
  • Benserazide Hydrochloride W/levodopa (100/25 Mg)
  • Entacapone (200 Mg/day)
  • Enablex (7.5 Mg, Unk)
  • Lactulose
  • Rivastigmine (2 Mg, Tid)
  • Amantadine Hcl (300 Mg/day)
  • Tolcapone (300 Mg/day)


Squamous Cell Carcinoma
Patient was taking Rasagiline Mesylate. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: squamous cell carcinoma on Jan 26, 2012 from ARGENTINA Additional patient health information: Male , weighting 165.3 lb, was diagnosed with and. Rasagiline Mesylate dosage: 1 Milligram; Ol- Adagio Fu, 1mg/day.

Squamous Cell Carcinoma
Adverse event was reported on Jan 24, 2012 by a Male taking Rasagiline Mesylate (Dosage: 1 Milligram; Ol- Adagio Fu, 1mg/day) was diagnosed with and. Location: ARGENTINA , weighting 165.3 lb, Patient felt the following Rasagiline side effects: squamous cell carcinoma.
Multiple prescriptions taken:
  • Carbidopa + Levodopa (100/25 Bid)


Hyperpyrexia, Muscle Rigidity, Neuroleptic Malignant Syndrome, Hypertonia, Serotonin Syndrome, Hyperhidrosis, Blood Creatine Phosphokinase Increased
on Sep 13, 2011 Male from , 81 years of age, was diagnosed with and was treated with Rasagiline. After Rasagiline was administered, patient encountered several Rasagiline side effects: hyperpyrexia, muscle rigidity, neuroleptic malignant syndrome, hypertonia, serotonin syndrome, hyperhidrosis, blood creatine phosphokinase increased. Rasagiline dosage: 1 Mg (1 Mg,1 In 1 D),oral.
Multiple concurrent drugs taken:
  • Midodrine Hydrochloride
  • Piperacillin And Tazobactam (pip/tazo)
  • Stalevo 100
  • Alendronate Sodium
  • Finasteride
  • Citalopram Hydrobromide (10 Mg (10 Mg,1 In 1 D),oral)
  • Calcium And Colecalciferol (lekovit Ca)
  • Omeprazole
Patient was hospitalized.

Aggression, Paranoia, Suicidal Ideation, Euphoric Mood, Excessive Exercise, Voyeurism, Panic Attack, Sudden Onset Of Sleep, Delusion
on Jul 12, 2011 Male from , 65 years of age, weighting 189.6 lb, was treated with Rasagiline Mesylate (rasagiline). Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: aggression, paranoia, suicidal ideation, euphoric mood, excessive exercise, voyeurism, panic attack, sudden onset of sleep, delusion. Rasagiline Mesylate (rasagiline) dosage: N/A.
Associated medications used:
  • Ropinirole (750 Micrograms, 3 In 1 D, Oral Use)
  • Requip Xl (36 Milligram, 1 In 1 D, Oral Use)
  • Co-careldopa (carbidopa, Levodopa) (carbidopa, Levodopa)
  • Sinemet (carbidopa, Carbidopa Monohydrate, Levodopa) (carbidopa, Carbi
Patient was hospitalized and became disabled.

Feeling Drunk, Tremor
Patient was taking Rasagiline. Patient felt the following Rasagiline side effects: feeling drunk, tremor on Jul 31, 2011 from UNITED STATES Additional patient health information: Male , weighting 229.3 lb, . Rasagiline dosage: 1 Mg, 1x/day.
Multiple prescriptions taken:
  • Neurontin (300 Mg, 3x/day)
  • Neurontin
  • Dyazide (Unk)
  • Neurontin


Obsessive Thoughts, Aggression, Dementia, Obsessive-compulsive Disorder, Libido Increased, Impulse-control Disorder, Excessive Sexual Fantasies, Personality Change, Withdrawal Syndrome
Adverse event was reported on Jan 07, 2011 by a Male taking Rasagiline Mesylate (Dosage: N/A) . Location: UNITED KINGDOM , 67 years of age, weighting 189.6 lb, After Rasagiline was administered, patient encountered several Rasagiline side effects: obsessive thoughts, aggression, dementia, obsessive-compulsive disorder, libido increased, impulse-control disorder, excessive sexual fantasies, personality change, withdrawal syndrome.
Multiple concurrent drugs taken:
  • Sinemet
  • Ropinirole
  • Requip Xl


Anaemia, Asthenia, Folate Deficiency, Gastritis Atrophic, Macrocytosis, Oedema Peripheral, Vitamin B12 Deficiency
on Oct 29, 2010 Male from ARGENTINA , weighting 172.0 lb, was diagnosed with and was treated with Rasagiline Mesylate. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: anaemia, asthenia, folate deficiency, gastritis atrophic, macrocytosis, oedema peripheral, vitamin b12 deficiency. Rasagiline Mesylate dosage: N/A. Patient was hospitalized.

Anaemia, Asthenia, Oedema Peripheral
on Oct 14, 2010 Male from ARGENTINA , weighting 172.0 lb, was diagnosed with and was treated with Rasagiline Mesylate. Patient felt the following Rasagiline side effects: anaemia, asthenia, oedema peripheral. Rasagiline Mesylate dosage: N/A. Patient was hospitalized.

Anaemia, Asthenia, Oedema Peripheral
Patient was taking Rasagiline Mesylate. After Rasagiline was administered, patient encountered several Rasagiline side effects: anaemia, asthenia, oedema peripheral on Oct 06, 2010 from ARGENTINA Additional patient health information: Male , weighting 172.0 lb, was diagnosed with and. Rasagiline Mesylate dosage: N/A. Patient was hospitalized.

Anaemia, Asthenia, Oedema Peripheral
Adverse event was reported on Sep 29, 2010 by a Male taking Rasagiline Mesylate (Dosage: N/A) was diagnosed with and. Location: ARGENTINA , weighting 172.0 lb, Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: anaemia, asthenia, oedema peripheral. Patient was hospitalized.

Convulsion, Hypersensitivity
on Aug 26, 2010 Female from UNITED STATES , 42 years of age, weighting 178.4 lb, was diagnosed with and was treated with Rasagiline. Patient felt the following Rasagiline side effects: convulsion, hypersensitivity. Rasagiline dosage: 1mg Daily Po. Patient was hospitalized.

Tardive Dyskinesia
on Nov 03, 2009 Male from UNITED STATES , 64 years of age, was treated with Rasagiline. After Rasagiline was administered, patient encountered several Rasagiline side effects: tardive dyskinesia. Rasagiline dosage: Po.

Confusional State, Hallucination, Visual
Patient was taking Rasagiline. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: confusional state, hallucination, visual on Sep 28, 2009 from SPAIN Additional patient health information: Female , 66 years of age, was diagnosed with and. Rasagiline dosage: 1 Mg/day.
Associated medications used:
  • Escitalopram (10 Mg/day)
Patient was hospitalized.

Diarrhoea, Nausea, Vomiting
Adverse event was reported on Jan 06, 2009 by a Male taking Rasagiline (Dosage: 1 Mg Every Day Po) was diagnosed with and. Location: UNITED STATES , 63 years of age, weighting 170.7 lb, Patient felt the following Rasagiline side effects: diarrhoea, nausea, vomiting.
Multiple prescriptions taken:
  • Carbidopa And Levodopa (50/200 Mg Bid Po)


Blood Pressure Inadequately Controlled, Hypertension
on Jan 05, 2009 Male from UNITED STATES , 79 years of age, was diagnosed with and was treated with Rasagiline. After Rasagiline was administered, patient encountered several Rasagiline side effects: blood pressure inadequately controlled, hypertension. Rasagiline dosage: 1 Mg Every Day Po.

Myocardial Infarction
on Dec 08, 2008 Female from SOUTH AFRICA , weighting 152.1 lb, was diagnosed with and was treated with Rasagiline Mesilate. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: myocardial infarction. Rasagiline Mesilate dosage: N/A.
Associated medications used:
  • Sinemet (100/25)
  • Bromocriptine
  • Amantadine Hcl
  • Metformin Hcl
  • Amlodipine
  • Enalapril Maleate


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Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:

     

    Side Effects

    Scale

    Date & Time

    Other Medicine(s) or Treatment(s)

     

     

     

     

    Scale: 1 = very mild to 10 = very bad


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  • You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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    More About Rasagiline

    Side Effects reported to FDA: 26

    Rasagiline safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 6

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