Renagel Side Effects
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Renagel Safety Reports reported to FDA
Total Renagel reports: 161.Renagel FDA safety alerts: No.
Reported deaths: 41 Reported hospitalizations: 96.
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Reported Renagel Side Effects: constipation, haemodialysis, large intestine perforation, gastrointestinal haemorrhage, diarrhoea, intestinal obstruction, peritonitis, abdominal distension, blood pressure decreased, diverticulitis, intestinal perforation.
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Renagel Side Effects Report #5445719-9Physician from UNITED STATES reported RENAGEL problem on Aug 21, 2007. Male patient, 91 years of age, weighting 183.0 lb, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: colitis ischaemic, convulsion, hypotension, sepsis, tachycardia. RENAGEL dosage: unknown. During the same period patient was treated with TOPROL, CARDIZEM, CELEBREX, NEPHROCAPS, FOSRENOL, VENOFER, COZAAR. Patient died on 07/21/2007.
Renagel Side Effects Report #5448201-8
RENAGEL problem was reported by a Physician from GREECE on Aug 23, 2007. Female patient, 81 years of age, weighting 137.8 lb, was diagnosed with hyperphosphataemia, pruritus and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: condition aggravated, hypersensitivity, pruritus, purpura. RENAGEL dosage: unknown. During the same period patient was treated with LOPRESSOR, SALOSPIR, PENRAZOL, ARANESP. Patient recovered.
Renagel Side Effects Report #5448439-X
Health Professional from UNITED STATES reported RENAGEL problem on Aug 22, 2007. Male patient, weighting 156.0 lb, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, refusal of treatment by patient. RENAGEL dosage: unknown. Patient died on 11/30/2006.
Renagel Side Effects Report #5449358-5
RENAGEL problem was reported by a Health Professional from AUSTRALIA on Aug 06, 2007. Male patient, 51 years of age, was diagnosed with renal failure chronic and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: anaemia, asthenia, constipation, dyspnoea, feeling abnormal, hypertension. RENAGEL dosage: unknown. During the same period patient was treated with NORVASC, CALTRATE, LIPITOR, FRUSEMIDE, SPIROLACTONE. Patient recovered.
Renagel Side Effects Report #5452123-6
Pharmacist from UNITED STATES reported RENAGEL problem on Aug 30, 2007. Female patient, 50 years of age, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: ammonia increased. RENAGEL dosage: unknown. Patient was hospitalized. Patient recovered.
Renagel Side Effects Report #5455364-7
RENAGEL problem was reported by a Physician from ICELAND on Aug 31, 2007. Female patient, 62 years of age, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: arteriovenous fistula site complication, hypothyroidism. RENAGEL dosage: unknown. During the same period patient was treated with LEVOTHYROXINE, AMLODIPINE, ENALAPRIL MALEATE, ESOMEPRAZOLE MAGNESIUM, PARACETAMOL, VITAMIN B CAP. Patient was hospitalized. Patient recovered.
Renagel Side Effects Report #5463944-8
Health Professional from UNITED STATES reported RENAGEL problem on Sept 04, 2007. Male patient, 66 years of age, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. RENAGEL dosage: unknown. During the same period patient was treated with INSULIN, IMDUR, NORVASC, ATENOLOL, ASPIRIN. Patient died on 07/11/2007.
Renagel Side Effects Report #5466091-4
RENAGEL problem was reported by a Physician from JAPAN on Sept 06, 2007. Male patient, 62 years of age, weighting 147.0 lb, was diagnosed with hyperphosphataemia, constipation and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: ascites, constipation, diverticular perforation, diverticulitis, haemodialysis, peritonitis. RENAGEL dosage: unknown. During the same period patient was treated with LAXAID, TELEMINSOFT, SELBEX, CALTAN, STOGAR, FUROSEMIDE, CLONAZEPAM. Patient was hospitalized. Patient recovered.
Renagel Side Effects Report #5466092-6
Physician from JAPAN reported RENAGEL problem on Sept 05, 2007. Female patient, 42 years of age, weighting 114.0 lb, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal pain, decreased appetite, diarrhoea, erosive duodenitis, gastritis erosive, gastrointestinal haemorrhage, melaena, palpitations. RENAGEL dosage: unknown. During the same period patient was treated with ALFAROL, HARNAL, NORVASC, LASIX, CALTAN. Patient was hospitalized. Patient recovered.
Renagel Side Effects Report #5470308-X
RENAGEL problem was reported by a Physician from UNITED STATES on Sept 13, 2007. Male patient, 47 years of age, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. RENAGEL dosage: unknown. Patient died on 08/10/2007.
Renagel Side Effects Report #5472145-9
Pharmacist from UNITED STATES reported RENAGEL problem on Sept 12, 2007. Female patient, 50 years of age, was diagnosed with hyperphosphataemia and was treated with RENAGEL. After drug was administered, patient experienced the following problems/side effects: ammonia increased. RENAGEL dosage: unknown. During the same period patient was treated with NIFEDIPINE, DIOVAN, SENSIPAR, GABAPENTIN, CLONIDINE, MINOXIDIL, LOMOTIL, OMEPRAZOLE. Patient was hospitalized. Patient recovered.
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Drug Information: Sevelamer
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601248.html
(se vel' a mer)Why is this medication prescribed?
Sevelamer is used to treat high blood levels of phosphorous in patients with kidney disease who are on dialysis. It binds phosphorous that you get from foods in your diet and prevents it from being absorbed into your blood stream.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?
Sevelamer comes as a capsule to take by mouth. It is usually taken three times a day with meals. Swallow the capsules whole. Do not chew or take the capsule apart before you swallow it. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sevelamer exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Sevelamer controls high blood levels of phosphorous which is a common problem in patients with kidney disease, but it does not cure the disease. Continue to take sevelamer even if you feel well. Do not stop taking sevelamer without talking to your doctor.
What special precautions should I follow?
Before taking sevelamer,
- tell your doctor and pharmacist if you are allergic to sevelamer or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including medications for seizures such as carbamazepine (Carbatrol, Epitol, Tegretol), ethosuximide (Zarontin), phenobarbital (Solfoton), and phenytoin (Dilantin); medications for irregular heartbeats such as amiodarone (Cordarone, Pacerone), digoxin (Lanoxin), diltiazem (Cardizem, Dilacor, Tiazac, others), disopyramide (Norpace), dolfetilide (Tikosyn), flecainide (Tambocor), ibutilide (Corvert), mexiletine (Mexitil), moricizine (Ethmozine), procainamide (Procanbid, Pronestyl, Rhythmin), propafenone (Rythmol), propanolol (Betachron ER, Inderal), quinidine, sotalol (Betapace), tocainide (Tonocard), and verapamil (Calan, Isoptin, Verelan, others); cyclosporine (Neoral, Sandimmune, Gengraf); lithium (Eskalith, Lithobid, others); theophylline (Slobid, Theo-Dur, others); warfarin (Coumadin); and herbal products and vitamins.
- If you are taking other medications, you should take them at least 1 hour before you take sevelamer or 3 hours after you have taken sevelamer, to prevent binding of your other medications.
- tell your doctor if you have or have ever had difficulty swallowing, a stomach or bowel problem such as blockage of your stomach or intestines, or surgery on your stomach or intestines.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking sevelamer, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking sevelamer.
What special dietary instructions should I follow?
Talk to your doctor about foods that contain high amounts of phosphorous. If your doctor prescribes a low-phosphorous diet, follow these directions carefully.
What should I do if I forget a dose?
Sevelamer should be taken with meals. If you remember that you forgot to take a dose within 1 hour of a meal, take the missed dose. Otherwise, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Sevelamer may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- upset stomach
- diarrhea
- vomiting
- gas (flatulence)
- constipation
- headache
- cough
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to determine your response to sevelamer.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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