RHEUMATREX Side Effects

5978098-9 | Condition Aggravated, Gastrointestinal Erosion, Humerus Fracture, Incorrect Dose Administered, Pancytopenia, Renal Impairment
on Nov 21, 2008 Female patient from JAPAN , weighting 108.0 lb, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?), hypertension, carotid artery stenosis and was treated with Rheumatrex (View Usage). Patient experienced the following unwanted or unexpected effects: condition aggravated, gastrointestinal erosion, humerus fracture, incorrect dose administered, pancytopenia, renal impairment. Rheumatrex dosage: . During the same period patient was treated with AMLODIPINE (View Amlodipine Review and Amlodipine Label ), CRESTOR (View Crestor Review and Crestor Label ), ACECOL (View Acecol Review and Acecol Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), DIOVAN (View Diovan Review and Diovan Label ), RIMATIL (View Rimatil Review and Rimatil Label ). Patient was hospitalized.

5726734-4 | Abdominal Pain, Cardiovascular Disorder, Fracture, Incorrect Dose Administered, Multi-organ Failure, Pancytopenia, Pyrexia, Renal Impairment, Vomiting
Patient was taking Rheumatrex (View Usage). Patient had the following side effects: abdominal pain (What is abdominal pain?), cardiovascular disorder, fracture (What is fracture?), incorrect dose administered, multi-organ failure, pancytopenia, pyrexia, renal impairment, vomiting on Apr 23, 2008 from JAPAN Additional patient health information: Female patient , 73 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and. Rheumatrex dosage: 6mg Weekly Prescribed But Pt. Non-compliant, Took Varing Doses. During the same period patient was treated with AMLODIPINE (View Amlodipine Review and Amlodipine Label ), RIMATIL (View Rimatil Review and Rimatil Label ), ACECOL (View Acecol Review and Acecol Label ), ACINON (View Acinon Review and Acinon Label ), DIOVAN (View Diovan Review and Diovan Label ), OSTELUC (View Osteluc Review and Osteluc Label ), CRESTOR (View Crestor Review and Crestor Label ). Patient was hospitalized.

5582014-1 | Pyrexia, Tuberculous Pleurisy
Adverse event was reported on Dec 26, 2007 by a Male patient taking Rheumatrex (View Usage) (Dosage: ) was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?), insomnia and. Location: JAPAN , weighting 112.0 lb, After Rheumatrex was administered, patient had the following side effects: pyrexia, tuberculous pleurisy. During the same period patient was treated with REMICADE (3 Mg) (View Remicade Review and Remicade Label ), PROGRAF (1 Mg) (View Prograf Review and Prograf Label ), MYSLEE (10 Mg) (View Myslee Review and Myslee Label ), MOBIC (10 Mg) (View Mobic Review and Mobic Label ), TAKEPRON (30 Mg) (View Takepron Review and Takepron Label ), PREDONINE (15 Mg) (View Predonine Review and Predonine Label ). Patient was hospitalized.

5530815-8 | Interstitial Lung Disease, Pneumonia Chlamydial
on Nov 28, 2007 Female patient from JAPAN , weighting 136.7 lb, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?), gastritis, analgesia and was treated with Rheumatrex (View Usage). Patient experienced the following unwanted or unexpected effects: interstitial lung disease, pneumonia chlamydial. Rheumatrex dosage: . During the same period patient was treated with SOLON (View Solon Review and Solon Label ), VOLTAREN (View Voltaren Review and Voltaren Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), SELTOUCH (View Seltouch Review and Seltouch Label ), OSTELUC (View Osteluc Review and Osteluc Label ). Patient was hospitalized.


5509857-4 | Interstitial Lung Disease, Pneumonia Chlamydial
on Oct 29, 2007 Female patient from JAPAN , weighting 136.7 lb, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?), gastritis, analgesia and was treated with Rheumatrex (View Usage). Patient had the following side effects: interstitial lung disease, pneumonia chlamydial. Rheumatrex dosage: . During the same period patient was treated with SOLON (View Solon Review and Solon Label ), VOLTAREN (View Voltaren Review and Voltaren Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), SELTOUCH (View Seltouch Review and Seltouch Label ), OSTELUC (View Osteluc Review and Osteluc Label ). Patient was hospitalized.

5490759-7 | Interstitial Lung Disease
Patient was taking Rheumatrex (View Usage). After Rheumatrex was administered, patient had the following side effects: interstitial lung disease on Oct 15, 2007 from JAPAN Additional patient health information: Female patient , 58 years of age, . Rheumatrex dosage: . During the same period patient was treated with OSTELUC (View Osteluc Review and Osteluc Label ).

5366958-1 | Interstitial Lung Disease
Adverse event was reported on Jun 11, 2007 by a Female patient taking Rheumatrex (View Usage) (Dosage: ) was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?), prophylaxis and. Location: JAPAN , weighting 66.14 lb, Patient experienced the following unwanted or unexpected effects: interstitial lung disease. During the same period patient was treated with HOCHUUEKKITOU (View Hochuuekkitou Review and Hochuuekkitou Label ), HYPEN (View Hypen Review and Hypen Label ), GASTER (View Gaster Review and Gaster Label ), REMICADE (View Remicade Review and Remicade Label ), FOLIAMIN (View Foliamin Review and Foliamin Label ). Patient was hospitalized.

5349630-3 | Interstitial Lung Disease
on May 29, 2007 Female patient from JAPAN , 78 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and was treated with Rheumatrex (View Usage). Patient had the following side effects: interstitial lung disease. Rheumatrex dosage: . During the same period patient was treated with OSTELUC (View Osteluc Review and Osteluc Label ). Patient was hospitalized.

5311705-2 | Choking, Condition Aggravated, Disseminated Intravascular Coagulation, Haemorrhage Subcutaneous, Listless, Melaena, Mental Status Changes, Multi-organ Failure, Myelodysplastic Syndrome
on Apr 24, 2007 Female patient from JAPAN , weighting 94.80 lb, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and was treated with Rheumatrex (View Usage). After Rheumatrex was administered, patient had the following side effects: choking (What is choking?), condition aggravated, disseminated intravascular coagulation, haemorrhage subcutaneous, listless, melaena, mental status changes, multi-organ failure, myelodysplastic syndrome. Rheumatrex dosage: . During the same period patient was treated with CYTOTEC (View Cytotec Review and Cytotec Label ), ARTANE (View Artane Review and Artane Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), RISPERDAL (View Risperdal Review and Risperdal Label ), LIVALO (View Livalo Review and Livalo Label ), NU LOTAN (View Nu-lotan Review and Nu-lotan Label ). Patient was hospitalized.

5067655-2 | Apparent Life Threatening Event, Pulmonary Embolism, Syncope
Patient was taking Rheumatrex (View Usage). Patient experienced the following unwanted or unexpected effects: apparent life threatening event, pulmonary embolism (What is pulmonary embolism?), syncope on Jul 24, 2006 from UNITED STATES Additional patient health information: Male patient , 59 years of age, was diagnosed with arthritis (What is arthritis?) and. Rheumatrex dosage: 10 Mg -1xw - Oral. During the same period patient was treated with ATENOLOL (View Atenolol Review and Atenolol Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ). Patient was hospitalized.

4911192-X | Antiphospholipid Syndrome, Brain Scan Abnormal, Cerebral Infarction, Delirium, Lupus Encephalitis, Pyrexia, Restlessness, Transient Ischaemic Attack
Adverse event was reported on Jan 26, 2006 by a Female patient taking Rheumatrex (View Usage) (Dosage: ) was diagnosed with sjogren's syndrome (What is sjogren's syndrome?) and. Location: JAPAN , 47 years of age, Patient had the following side effects: antiphospholipid syndrome, brain scan abnormal, cerebral infarction, delirium, lupus encephalitis, pyrexia, restlessness, transient ischaemic attack. During the same period patient was treated with NABOAL SR (DICLOFENAC SODIUM) (View Naboal Sr (diclofenac Sodium) Review and Naboal Sr (diclofenac Sodium) Label ), ACTINON (NIZATIDINE) (View Actinon (nizatidine) Review and Actinon (nizatidine) Label ), SELBEX (TEPRENONE) (View Selbex (teprenone) Review and Selbex (teprenone) Label ), RISEDRONATE SODIUM (View Risedronate Sodium Review and Risedronate Sodium Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), METHYCOBAL (MECOBALAMINE) (View Methycobal (mecobalamine) Review and Methycobal (mecobalamine) Label ), NEUTROPIN (ORGAN LYSATE, STANDARDIZED) (View Neutropin (organ Lysate, Standardized) Review and Neutropin (organ Lysate, Standardized) Label ), EVOXAC (Oral) (View Evoxac Review and Evoxac Label ). Patient was hospitalized.

4818398-9 | Asthma, Bone Marrow Failure, Pneumonia
on Jun 01, 2005 Female patient from JAPAN , 79 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and was treated with Rheumatrex (View Usage). After Rheumatrex was administered, patient had the following side effects: asthma (What is asthma?), bone marrow failure, pneumonia (What is pneumonia?). Rheumatrex dosage: 4 Mg - 1xw - Oral. During the same period patient was treated with DICLOFENAC SODIUM (View Diclofenac Sodium Review and Diclofenac Sodium Label ), ORGAN LYSATE, STANDARDIZED (View Organ Lysate, Standardized Review and Organ Lysate, Standardized Label ), LIMAPROST (View Limaprost Review and Limaprost Label ), LEVOGLUTAMIDE/SODIUM GUALENATE (View Levoglutamide/sodium Gualenate Review and Levoglutamide/sodium Gualenate Label ), DIFENIDOL HYDROCHLORIDE (View Difenidol Hydrochloride Review and Difenidol Hydrochloride Label ), BETAHISTINE HYDROCHLORIDE (View Betahistine Hydrochloride Review and Betahistine Hydrochloride Label ). Patient was hospitalized.

4743962-5 | Bone Marrow Depression, Fungal Infection, Pleural Effusion, Pneumonia, Septic Shock, Staphylococcal Infection, Stomatitis
on Jul 27, 2005 Female patient from JAPAN , 82 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and was treated with Rheumatrex (View Usage). Patient experienced the following unwanted or unexpected effects: bone marrow depression, fungal infection (What is fungal infection?), pleural effusion, pneumonia (What is pneumonia?), septic shock, staphylococcal infection (What is staphylococcal infection?), stomatitis. Rheumatrex dosage: 2 + 4 + 6 + 8 Mg 1x Per 1 Wk Oral - See Image. During the same period patient was treated with MINOCYCLINE HCL (200 Mg 1x Per 1 Day Oral) (View Minocycline Hcl Review and Minocycline Hcl Label ), VOLTAREN (View Voltaren Review and Voltaren Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), STARLIX (View Starlix Review and Starlix Label ), COTRIM (View Cotrim Review and Cotrim Label ), FAMOTIDINE (View Famotidine Review and Famotidine Label ), SIGMART (NICORANDIL) (View Sigmart (nicorandil) Review and Sigmart (nicorandil) Label ). Patient was hospitalized.

4714295-8 | Bone Marrow Depression, Fungal Infection, Pleural Effusion, Pneumonia, Septic Shock, Staphylococcal Infection, Stomatitis
Patient was taking Rheumatrex (View Usage). Patient had the following side effects: bone marrow depression, fungal infection (What is fungal infection?), pleural effusion, pneumonia (What is pneumonia?), septic shock, staphylococcal infection (What is staphylococcal infection?), stomatitis on Jun 30, 2005 from JAPAN Additional patient health information: Female patient , 82 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and. Rheumatrex dosage: See Image. During the same period patient was treated with MINOCYCLINE HCL (200 Mg 1x Per 1 Day Oral) (View Minocycline Hcl Review and Minocycline Hcl Label ), VOLTAREN (View Voltaren Review and Voltaren Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), STARLIX (View Starlix Review and Starlix Label ), COTRIM (View Cotrim Review and Cotrim Label ), FAMOTIDINE (View Famotidine Review and Famotidine Label ). Patient was hospitalized.

4621596-0 | Cholangitis, Escherichia Bacteraemia
Adverse event was reported on Oct 19, 2004 by a Male patient taking Rheumatrex (View Usage) (Dosage: 6 Mg Weekly) was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and. Location: , 65 years of age, After Rheumatrex was administered, patient had the following side effects: cholangitis, escherichia bacteraemia. During the same period patient was treated with INFLIXIMAB (3 Mg/kg) (View Infliximab Review and Infliximab Label ), ISONIAZID (View Isoniazid Review and Isoniazid Label ), PREDONINE (View Predonine Review and Predonine Label ), CLINORIL (View Clinoril Review and Clinoril Label ), FOLIC ACID (View Folic Acid Review and Folic Acid Label ). Patient was hospitalized.

4617697-3 | Blood Urea Increased, Bone Marrow Depression, C-reactive Protein Increased, Cardiac Arrest, Cardiomegaly, Cytomegalovirus Infection, Diarrhoea, Dyspnoea, Gastrointestinal Disorder
on Mar 11, 2005 Female patient from , 75 years of age, was treated with Rheumatrex (View Usage). Patient experienced the following unwanted or unexpected effects: blood urea increased, bone marrow depression, c-reactive protein increased, cardiac arrest (What is cardiac arrest?), cardiomegaly, cytomegalovirus infection (What is cytomegalovirus infection?), diarrhoea, dyspnoea, gastrointestinal disorder. Rheumatrex dosage: 2 Mg Weekly, Po; 2 Mg Weekly, Po; 4 Mg Weekly, Po; 6 Mg Weekly, Po. During the same period patient was treated with METHYLPREDNISOLONE (View Methylprednisolone Review and Methylprednisolone Label ), MISOPROSTOL (View Misoprostol Review and Misoprostol Label ), ROXATIDINE ACETATE HCL (View Roxatidine Acetate Hcl Review and Roxatidine Acetate Hcl Label ), CALCITRIOL (View Calcitriol Review and Calcitriol Label ). Patient was hospitalized.

4617016-2 | Aspartate Aminotransferase Increased, Blood Albumin Decreased, Blood Alkaline Phosphatase Increased, Blood Lactate Dehydrogenase Increased, Cardiac Arrest, Chlamydial Infection, Interstitial Lung Disease, Pneumocystis Jiroveci Pneumonia
on May 25, 2004 Male patient from , 67 years of age, was treated with Rheumatrex (View Usage). Patient had the following side effects: aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, cardiac arrest (What is cardiac arrest?), chlamydial infection, interstitial lung disease, pneumocystis jiroveci pneumonia. Rheumatrex dosage: 4 Mg 1x Per 1 Wk, Oral. During the same period patient was treated with MEDROL (6 Mg 1x Per 1 Day, Intravenous) (View Medrol Review and Medrol Label ), METHOTREXATE (2.5-5.0 Mg Weekly, Oral) (View Methotrexate Review and Methotrexate Label ), REMICADE (3 Mg/kg/day, Intravenous) (View Remicade Review and Remicade Label ). Patient was hospitalized.

4597184-1 | Abasia, Blood Alkaline Phosphatase Increased, Fall, Pancytopenia, Pyrexia, Sepsis, Stomatitis
Patient was taking Rheumatrex (View Usage). After Rheumatrex was administered, patient had the following side effects: abasia, blood alkaline phosphatase increased, fall (What is fall?), pancytopenia, pyrexia, sepsis (What is sepsis?), stomatitis on Feb 15, 2005 from Additional patient health information: Female patient , 77 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and. Rheumatrex dosage: 6 Mg Per Week; Oral. During the same period patient was treated with KEPHTON TWO (MENATETRENONE, ) (Oral) (View Kephton-two (menatetrenone, ) Review and Kephton-two (menatetrenone, ) Label ), LANDEL (EFONIDIPINE HYDROCHLORIDE, ) (Oral) (View Landel (efonidipine Hydrochloride, ) Review and Landel (efonidipine Hydrochloride, ) Label ), MAGNESIUM OXIDE (MAGNESIUM OXIDE, ) (Oral) (View Magnesium Oxide (magnesium Oxide, ) Review and Magnesium Oxide (magnesium Oxide, ) Label ), MOVER (ACTARIT, ) (Oral) (View Mover (actarit, ) Review and Mover (actarit, ) Label ), OSTELUC (ETODOLAC, CAPSULE) (Oral) (View Osteluc (etodolac, Capsule) Review and Osteluc (etodolac, Capsule) Label ), PREDNISOLONE (Oral) (View Prednisolone Review and Prednisolone Label ), RIMATIL (BUCILLAMINE, ) (Oral) (View Rimatil (bucillamine, ) Review and Rimatil (bucillamine, ) Label ), TIEKAPTO (CIMETIDINE, ) (Oral) (View Tiekapto (cimetidine, ) Review and Tiekapto (cimetidine, ) Label ). Patient was hospitalized.

4585943-0 | Blood Beta-d-glucan Decreased, Dyspnoea, Interstitial Lung Disease, Malaise, Nausea, Pulmonary Haemorrhage
Adverse event was reported on Jan 31, 2005 by a Female patient taking Rheumatrex (View Usage) (Dosage: 8 Mg 1x Per 1 Wk Oral) was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?), depression (What is depression?), pollakiuria and. Location: , 31 years of age, Patient experienced the following unwanted or unexpected effects: blood beta-d-glucan decreased, dyspnoea, interstitial lung disease, malaise, nausea (What is nausea?), pulmonary haemorrhage. During the same period patient was treated with ABILIT (SULPIRIDE,) (150 Mg 1x Per 1 Day Oral) (View Abilit (sulpiride,) Review and Abilit (sulpiride,) Label ), BUP 4 (PROPIVERINE HYDROCHLORIDE,) (20 Mg 1x Per 1 Day Oral) (View Bup-4 (propiverine Hydrochloride,) Review and Bup-4 (propiverine Hydrochloride,) Label ), ETODOLAC (See Image) (View Etodolac Review and Etodolac Label ), MEILAX (ETHYL LOFLAZEPATE,) (2 Mg 1x Per 1 Day Oral) (View Meilax (ethyl Loflazepate,) Review and Meilax (ethyl Loflazepate,) Label ), PREDNISONE (See Image) (View Prednisone Review and Prednisone Label ). Patient was hospitalized.

4546770-3 | Alopecia, Dizziness, Epistaxis, Interstitial Lung Disease, Paraesthesia, Respiratory Failure, Stomatitis, White Blood Cell Count Decreased
on Nov 10, 2004 Female patient from , 67 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and was treated with Rheumatrex (View Usage). Patient had the following side effects: alopecia, dizziness (What is dizziness?), epistaxis, interstitial lung disease, paraesthesia, respiratory failure, stomatitis, white blood cell count decreased. Rheumatrex dosage: 6 Mg 1x Per 1 Wk; Oral, 4 Mg 1x Per 1 Wk, 6mg 1x Per 1 Wk. During the same period patient was treated with CALCITROL (CALCIUM CARBONATE/CRGOCALCIFEROL/RETINOL) (View Calcitrol (calcium Carbonate/crgocalciferol/retinol) Review and Calcitrol (calcium Carbonate/crgocalciferol/retinol) Label ), EPINASTINE HYDROCHLORIDE (EPINASTINE HYDROCHLORIDE) (View Epinastine Hydrochloride (epinastine Hydrochloride) Review and Epinastine Hydrochloride (epinastine Hydrochloride) Label ), LOXONIN (LOXOPROFEN SODIUM) (View Loxonin (loxoprofen Sodium) Review and Loxonin (loxoprofen Sodium) Label ), MEFENAMIC ACID (View Mefenamic Acid Review and Mefenamic Acid Label ), NORVASC (View Norvasc Review and Norvasc Label ). Patient was hospitalized.

4545294-7 | Bone Marrow Depression, Fungal Infection, Pleural Effusion, Pneumonia, Septic Shock, Staphylococcal Infection, Stomatitis
on Dec 21, 2004 Female patient from , 82 years of age, was diagnosed with rheumatoid arthritis (What is rheumatoid arthritis?) and was treated with Rheumatrex (View Usage). After Rheumatrex was administered, patient had the following side effects: bone marrow depression, fungal infection (What is fungal infection?), pleural effusion, pneumonia (What is pneumonia?), septic shock, staphylococcal infection (What is staphylococcal infection?), stomatitis. Rheumatrex dosage: See Image. During the same period patient was treated with BONALON (ALENDRONATE SODIUM) (View Bonalon (alendronate Sodium) Review and Bonalon (alendronate Sodium) Label ), MINOCYCLINE HCL (200 Mg 1x Per 1 Day) (View Minocycline Hcl Review and Minocycline Hcl Label ), VOLTAREN (View Voltaren Review and Voltaren Label ). Patient was hospitalized.