Rituximab Safety Questions, Rituximab Answers
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Rituximab Safety Reports
Total Rituximab reports: 398.Rituximab FDA safety alerts: 2004 2006 .
Reported deaths: 76 Reported hospitalizations: 240.
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Reported Rituximab Side Effects: febrile neutropenia, neutropenia, infusion related reaction, pneumonia cytomegaloviral, pyrexia, gastric cancer, deep vein thrombosis, respiratory failure, chills, pulmonary embolism, pneumocystis jiroveci pneumonia.
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Showing 1-50 of 398 Next >
Rituximab Side Effects Report #5311438-2Physician from UNITED KINGDOM reported RITUXIMAB problem on Apr 26, 2007. Male patient, weighting 220.5 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: brain abscess. RITUXIMAB dosage: 1050 MG, UNK. During the same period patient was treated with FLUDARABINE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5311706-4
RITUXIMAB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 20, 2007. Male patient, weighting 183.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: tuberculosis. RITUXIMAB dosage: 975 MG, UNK. During the same period patient was treated with FLUDARABINE, CYCLOPHOSPHAMIDE, OMEPRAZOLE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5311718-0
Physician from UNITED STATES reported RITUXIMAB problem on Apr 18, 2007. Female patient, weighting 125.7 lb, was diagnosed with systemic lupus erythematosus and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: histoplasmosis. RITUXIMAB dosage: 1000 MG, X4. During the same period patient was treated with BIAXIN, CELLCEPT, PREDNISONE, DILTIAZEM, HYDROCHLOROTHIAZIDE, QUINAPRIL, NEXIUM, CALCIUM SUPPLEMENT. Patient recovered.
Rituximab Side Effects Report #5314671-9
RITUXIMAB problem was reported by a Consumer or non-health professional from on Apr 19, 2007. Male patient, 79 years of age, was diagnosed with lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: haemopneumothorax, histiocytosis haematophagic, hypotension, hypoxia, interstitial lung disease, tachycardia. RITUXIMAB dosage: 375 MG/M2, UNK. During the same period patient was treated with BETAMETHASONE, DIPHENHYDRAMINE, PARACETAMOL. Patient died.
Rituximab Side Effects Report #5315061-5
Consumer or non-health professional from GERMANY reported RITUXIMAB problem on Apr 23, 2007. Female patient, weighting 158.7 lb, was diagnosed with rheumatoid arthritis, osteoporosis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: multi-organ failure, staphylococcal sepsis. RITUXIMAB dosage: 1000 MG, SINGLE. During the same period patient was treated with INFLIXIMAB, METHOTREXATE, MELYSDON, TERIPARATIDE, CALCIUM D, MOBLOC, RAMIPRIL. Patient was hospitalized. Patient died on 04/21/2007.
Rituximab Side Effects Report #5315651-X
RITUXIMAB problem was reported by a Physician from UNITED KINGDOM on Apr 23, 2007. Male patient, 72 years of age, was diagnosed with b-cell small lymphocytic lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: diffuse large b-cell lymphoma. RITUXIMAB dosage: unknown. Patient recovered.
Rituximab Side Effects Report #5317200-9
Consumer or non-health professional from UNITED KINGDOM reported RITUXIMAB problem on Apr 23, 2007. Male patient, 58 years of age, was diagnosed with liver transplant, immunosuppression and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, cytomegalovirus infection, pneumocystis jiroveci infection, sepsis. RITUXIMAB dosage: 375 MG/M2, 1/WEEK. During the same period patient was treated with PLASMA EXCHANGE, TACROLIMUS, STEROIDS, MYCOPHENOLATE MOFETIL, PROSTAGLANDIN E, METHYLPREDNISOLONE, PROTEASE INHIBITOR. Patient died.
Rituximab Side Effects Report #5317350-7
RITUXIMAB problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 25, 2007. Male patient, weighting 183.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: tuberculosis. RITUXIMAB dosage: 975 MG, UNK. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, OMEPRAZOLE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5318223-6
Physician from UNITED KINGDOM reported RITUXIMAB problem on Apr 25, 2007. Female patient was diagnosed with chronic lymphocytic leukaemia, haemolysis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: haemolysis. RITUXIMAB dosage: 500 MG, Q28D. During the same period patient was treated with FLUDARABINE, CYCLOPHOSPHAMIDE, PARACETAMOL, STEROID NOS, ERYTHROCYTE TRANSFUSIONS, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5318400-4
RITUXIMAB problem was reported by a Physician from UNITED STATES on Apr 25, 2007. Female patient, weighting 160.3 lb, was diagnosed with rheumatoid arthritis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: chest discomfort. RITUXIMAB dosage: 1000 MG, UNK. During the same period patient was treated with PREDNISONE, PLAVIX, CRESTOR, SINGULAIR, ASPIRIN, SEREVENT, COMBIVENT. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5318890-7
Physician from SWITZERLAND reported RITUXIMAB problem on Apr 30, 2007. Female patient, 62 years of age, was diagnosed with b-cell lymphoma, prophylaxis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: reversible posterior leukoencephalopathy syndrome. RITUXIMAB dosage: 375 MG/M2, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, NEUPOGEN. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5320092-5
RITUXIMAB problem was reported by a Consumer or non-health professional from FRANCE on May 02, 2007. Male patient, weighting 121.3 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: gastric cancer. RITUXIMAB dosage: 596.25 MG, Q3W. During the same period patient was treated with CYCLOPHOSPHAMIDE, ADRIAMYCIN PFS, VINCRISTINE, PREDNISOLONE. Patient recovered.
Rituximab Side Effects Report #5320108-6
Physician from UNITED KINGDOM reported RITUXIMAB problem on May 03, 2007. Female patient, weighting 145.5 lb, was diagnosed with chronic lymphocytic leukaemia, prophylaxis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, cardiac failure, embolism, haemolysis, tumour lysis syndrome. RITUXIMAB dosage: 700 MG, Q28D. During the same period patient was treated with FLUDARABINE, CYCLOPHOSPHAMIDE, SUMETROLIM, QUAMATEL, ONDANSETRON, ACICLOVIRUM, METHYLPREDNISOLONE. Patient died on 04/17/2006.
Rituximab Side Effects Report #5320729-0
RITUXIMAB problem was reported by a Physician from FRANCE on May 02, 2007. Male patient, weighting 143.3 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis. RITUXIMAB dosage: 650 MG, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, VINCRISTINE. Patient recovered.
Rituximab Side Effects Report #5322231-9
Physician from FRANCE reported RITUXIMAB problem on May 02, 2007. Male patient, weighting 160.9 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: lung adenocarcinoma. RITUXIMAB dosage: 375 MG/M2, Q3W. During the same period patient was treated with CORTANCYL, ONCOVIN, ADRIAMYCIN PFS, ENDOXAN. Patient recovered.
Rituximab Side Effects Report #5322265-4
RITUXIMAB problem was reported by a Consumer or non-health professional from FRANCE on Oct 10, 2006. Female patient, weighting 264.6 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cholecystitis. RITUXIMAB dosage: 375 MG/M2, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, PREDNISONE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5322314-3
Physician from UNITED KINGDOM reported RITUXIMAB problem on May 03, 2007. Female patient, weighting 97.00 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: respiratory failure. RITUXIMAB dosage: 900 MG, Q4W. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, DIHYDROCODEINE BITARTRATE, SULFAMETHOXAZOLE, TRIMETHOPRIM. Patient died on 09/27/2006.
Rituximab Side Effects Report #5322507-5
RITUXIMAB problem was reported by a Physician from AUSTRALIA on May 04, 2007. Female patient, weighting 154.3 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia. RITUXIMAB dosage: 668 MG, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, DOXORUBICIN, PREDNISOLONE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5322774-8
Consumer or non-health professional from CANADA reported RITUXIMAB problem on May 01, 2007. Male patient, weighting 154.8 lb, was diagnosed with multiple sclerosis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: pneumonia. RITUXIMAB dosage: 1000 MG, DAYS 1+15. Patient was hospitalized. Patient died on 12/05/2005.
Rituximab Side Effects Report #5322836-5
RITUXIMAB problem was reported by a Physician from UNITED KINGDOM on May 09, 2007. Female patient, weighting 125.2 lb, was diagnosed with vasculitis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: pneumonia, pulmonary embolism. RITUXIMAB dosage: 562 MG, 1/WEEK. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, ADCAL, AMPHOTERICIN B LOZENGES, DIGOXIN, FUROSEMIDE, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5323926-3
Consumer or non-health professional from UNITED STATES reported RITUXIMAB problem on May 04, 2007. Female patient, 20 years of age, was diagnosed with lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage. RITUXIMAB dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5323938-X
RITUXIMAB problem was reported by a Physician from UNITED KINGDOM on May 08, 2007. Female patient, weighting 125.2 lb, was diagnosed with vasculitis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cytomegalovirus infection. RITUXIMAB dosage: 562 MG, 1/WEEK. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, ADCAL, AMPHOTERICIN B LOZENGES, DIGOXIN, FUROSEMIDE, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5324280-3
Physician from JAPAN reported RITUXIMAB problem on May 08, 2007. Male patient, 65 years of age, weighting 122.4 lb, was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: gastric cancer. RITUXIMAB dosage: 375 MG/M2, 1X/DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, FLUDARABINE PHOSPHATE, FLUDARABINE PHOSPHATE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5325101-5
RITUXIMAB problem was reported by a Physician from UNITED KINGDOM on May 07, 2007. Male patient was diagnosed with non-hodgkin's lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia. RITUXIMAB dosage: 730 MG, UNK. During the same period patient was treated with CISPLATIN, DEXAMETHASONE, NEUPOGEN. Patient was hospitalized. Patient died on 05/04/2007.
Rituximab Side Effects Report #5325249-5
Physician from UNITED STATES reported RITUXIMAB problem on May 07, 2007. Female patient, weighting 125.7 lb, was diagnosed with systemic lupus erythematosus and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: histoplasmosis. RITUXIMAB dosage: 1000 MG, X4. During the same period patient was treated with BIAXIN, CELLCEPT, PREDNISONE, DILTIAZEM, HYDROCHLOROTHIAZIDE, QUINAPRIL, NEXIUM, CALCIUM SUPPLEMENT. Patient recovered.
Rituximab Side Effects Report #5326239-9
RITUXIMAB problem was reported by a Physician from UNITED KINGDOM on May 10, 2007. Female patient, weighting 98.77 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: septic shock. RITUXIMAB dosage: 600 MG, Q28D. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, INSULIN RETARD LEO, FLUKONAZOL. Patient died on 05/01/2007.
Rituximab Side Effects Report #5326246-6
Physician from UNITED KINGDOM reported RITUXIMAB problem on May 10, 2007. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: oesophageal candidiasis. RITUXIMAB dosage: 600 MG, Q28D. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, INSULIN RETARD LEO, SEPTRA, PAROXETINE, FORTASEC. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5326281-8
RITUXIMAB problem was reported by a Physician from ITALY on May 04, 2007. Female patient, weighting 127.9 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: overdose. RITUXIMAB dosage: 375 MG, UNK. Patient recovered.
Rituximab Side Effects Report #5326832-3
Physician from GERMANY reported RITUXIMAB problem on May 08, 2007. Female patient, weighting 165.3 lb, was diagnosed with rheumatoid arthritis, osteoporosis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: anaemia, multi-organ failure, pleural effusion, pneumonia, staphylococcal sepsis. RITUXIMAB dosage: 1000 MG, SINGLE. During the same period patient was treated with INFLIXIMAB, METHOTREXATE, MELYSDON, TERIPARATIDE, CALCIUM D, MOBLOC, RAMIPRIL. Patient was hospitalized. Patient died on 04/21/2007.
Rituximab Side Effects Report #5328765-5
RITUXIMAB problem was reported by a Health Professional from FRANCE on May 11, 2007. Male patient was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cerebral haematoma, paranoia, status epilepticus. RITUXIMAB dosage: 575 MG/M2, UNK. During the same period patient was treated with CORTANCYL, ENDOXAN, FARMARUBICINE, ELDISINE, METHOTREXATE, RIMIFON. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5328857-0
Physician from UNITED KINGDOM reported RITUXIMAB problem on May 11, 2007. Female patient, weighting 149.9 lb, was diagnosed with rheumatoid arthritis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cough, cryptogenic organising pneumonia. RITUXIMAB dosage: 1000 MG, QD. During the same period patient was treated with FOSAMAX, CORTANCYL, METHOTREXATE, SPECIAFOLDINE. Patient recovered.
Rituximab Side Effects Report #5330081-2
RITUXIMAB problem was reported by a Physician from GERMANY on May 11, 2007. Female patient, weighting 143.3 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: condition aggravated. RITUXIMAB dosage: 660 MG, SINGLE. During the same period patient was treated with BENDAMUSTINE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5330458-5
Physician from UNITED STATES reported RITUXIMAB problem on May 10, 2007. Male patient, 29 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: leukoencephalopathy. RITUXIMAB dosage: 10 MG, 1/WEEK, WK 1. During the same period patient was treated with GLUCOCORTICOIDS, ACETAMINOPHEN, DIPHENHYDRAMINE. Patient recovered.
Rituximab Side Effects Report #5332797-0
RITUXIMAB problem was reported by a Consumer or non-health professional from UNITED STATES on May 23, 2007. Female patient was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident. RITUXIMAB dosage: unknown. During the same period patient was treated with CISPLATIN, CYTARABINE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5333184-1
Pharmacist from UNITED STATES reported RITUXIMAB problem on May 21, 2007. Male patient, weighting 218.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: back pain, hypotension, pruritus, syncope, tachycardia. RITUXIMAB dosage: 935 MG ONCE IV. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5333601-7
RITUXIMAB problem was reported by a Physician from JAPAN on May 17, 2007. Female patient, weighting 99.21 lb, was diagnosed with systemic lupus erythematosus, gastritis, osteoporosis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: myelitis transverse. RITUXIMAB dosage: 1000 MG, 1/WEEK. During the same period patient was treated with ACETAMINOPHEN, POLARAMINE, SAXIZON, NIZATIDINE, CALCIUM CHLORIDE. Patient recovered.
Rituximab Side Effects Report #5334416-6
Consumer or non-health professional from UNITED STATES reported RITUXIMAB problem on May 23, 2007. Female patient, weighting 114.2 lb, was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: asthenia, atelectasis, breath sounds abnormal, confusional state, delirium, pyrexia, respiratory distress, wheezing. RITUXIMAB dosage: 1156 MG. Patient recovered.
Rituximab Side Effects Report #5334864-4
RITUXIMAB problem was reported by a Physician from UNITED STATES on May 18, 2007. Female patient, weighting 160.3 lb, was diagnosed with rheumatoid arthritis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: chest discomfort. RITUXIMAB dosage: 1000 MG, UNK. During the same period patient was treated with PREDNISONE, PLAVIX, CRESTOR, SINGULAIR, ASPIRIN, SEREVENT, COMBIVENT. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5335058-9
Consumer or non-health professional from UNITED STATES reported RITUXIMAB problem on May 15, 2007. Female patient, 20 years of age, was diagnosed with lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage. RITUXIMAB dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5335060-7
RITUXIMAB problem was reported by a Physician from JAPAN on May 17, 2007. Female patient was diagnosed with systemic lupus erythematosus and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. RITUXIMAB dosage: 1000 MG/BODY 2 TIMES. Patient died on 03/24/2007.
Rituximab Side Effects Report #5335097-8
Health Professional from UNITED STATES reported RITUXIMAB problem on Jan 08, 2007. Female patient, weighting 205.0 lb, was diagnosed with rheumatoid arthritis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: refusal of treatment by patient, rheumatoid arthritis. RITUXIMAB dosage: 1000 MG, X2. During the same period patient was treated with ACETAMINOPHEN, IBUPROFEN, FOLIC ACID, METHOTREXATE, ALESSE, SLOW FE, NAPROXEN. Patient recovered.
Rituximab Side Effects Report #5337324-X
RITUXIMAB problem was reported by a Physician from JAPAN on May 17, 2007. Female patient was diagnosed with systemic lupus erythematosus and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: systemic lupus erythematosus. RITUXIMAB dosage: 1000 MG/BODY. During the same period patient was treated with IMMUNOSUPPRESSANT NOS. Patient recovered.
Rituximab Side Effects Report #5338577-4
Physician from UNITED KINGDOM reported RITUXIMAB problem on May 24, 2007. Male patient was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, coronary artery disease, pneumonia cytomegaloviral. RITUXIMAB dosage: 375 MG/M2, X4. During the same period patient was treated with CYCLOPHOSPHAMIDE, PREDNISOLONE, DILTIAZEM, ISOSORBIDE MONONITRATE, PERINDOPRIL ERBUMINE. Patient was hospitalized. Patient died on 12/26/2006.
Rituximab Side Effects Report #5338912-7
RITUXIMAB problem was reported by a Physician from JAPAN on May 17, 2007. Female patient, weighting 99.21 lb, was diagnosed with systemic lupus erythematosus, gastritis, osteoporosis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: myelitis transverse. RITUXIMAB dosage: 1000 MG, 1/WEEK. During the same period patient was treated with ACETAMINOPHEN, POLARAMINE, SAXIZON, NIZATIDINE, CALCIUM CHLORIDE. Patient recovered.
Rituximab Side Effects Report #5340205-9
Consumer or non-health professional from UNITED KINGDOM reported RITUXIMAB problem on May 23, 2007. Female patient, weighting 154.3 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: neuropathy. RITUXIMAB dosage: 375 MG/M2, UNK. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, COTRIMOXAZOLE, VALACYCLOVIR. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5340495-2
RITUXIMAB problem was reported by a Physician from UNITED KINGDOM on May 22, 2007. Female patient, weighting 198.4 lb, was diagnosed with non-hodgkin's lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, septic shock. RITUXIMAB dosage: unknown. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5341874-X
Consumer or non-health professional from UNITED STATES reported RITUXIMAB problem on May 29, 2007. Female patient, 69 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, intestinal perforation, white blood cell count decreased. RITUXIMAB dosage: 825MG. During the same period patient was treated with CYCLOPHOSPHAMIDE, PREDNISONE, VINCRISTINE, ASPIRIN, GLUCOSAMINE, CALCIUM CHLORIDE, TOLTERODINE, ENALAPRIL MALEATE. Patient recovered.
Rituximab Side Effects Report #5341936-7
RITUXIMAB problem was reported by a Physician from JAPAN on May 25, 2007. Male patient, weighting 152.1 lb, was diagnosed with non-hodgkin's lymphoma, anaemia, hepatic cirrhosis, prophylaxis and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, tumour lysis syndrome. RITUXIMAB dosage: 375 MG, QD. During the same period patient was treated with FERROMIA, LASIX, ALDACTONE, URSO, OCTOTIAMINE, ASPARA, CHINESE MEDICINE, MOSAPRIDE CITRATE. Patient recovered.
Rituximab Side Effects Report #5341963-X
Consumer or non-health professional from FRANCE reported RITUXIMAB problem on May 29, 2007. Male patient, weighting 140.0 lb, was diagnosed with b-cell lymphoma and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, leukopenia, sinusitis. RITUXIMAB dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, PARACETAMOL, CETIRIZINE, VINCRISTINE. Patient was hospitalized. Patient recovered.
Rituximab Side Effects Report #5342397-4
RITUXIMAB problem was reported by a Physician from JAPAN on May 24, 2007. Male patient was diagnosed with systemic lupus erythematosus and was treated with RITUXIMAB. After drug was administered, patient experienced the following problems/side effects: hypogammaglobulinaemia. RITUXIMAB dosage: 200 MG, QD. During the same period patient was treated with CELLCEPT, AZATHIOPRINE, ENDOXAN, DIAMOX, PREDNISOLONE, BAKTAR. Patient was hospitalized. Patient recovered.
Showing 1-50 of 398 Next >
Drug Information: Rituximab Injection
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607038.html
ri tux' i mabIMPORTANT WARNING:
| Some people who received rituximab experienced severe reactions to the medication. Some of these people died within 24 hours after they received a dose of rituximab. Most of these deaths happened after the first dose of rituximab. Tell your doctor if you have or have ever had chronic lymphocytic leukemia (CLL; a type of cancer that begins in the white blood cells), mantle cell lymphoma (a fast-growing cancer that begins in the cells of the immune system), an irregular heartbeat, or heart or lung disease. If you have any of these conditions, or if you are female, there is a greater chance that you will experience a serious reaction to rituximab. If you experience any of the following symptoms, tell your doctor or other health care provider immediately: hives; swelling of the lips, tongue, or throat; difficulty breathing or swallowing; dizziness; fainting; shortness of breath, wheezing; blurred vision; headache; pounding or irregular heartbeat; fast or weak pulse; loss of consciousness, fast breathing; pale or bluish skin; pain in the chest that may spread to other parts of the upper body; weakness; excessive tiredness; sweating; or anxiety.When rituximab is used to treat non-Hodgkin's lymphoma (NHL; a type of cancer that begins in a type of white blood cells that normally fight infection) it may cause a condition called tumor lysis syndrome (TLS; a group of symptoms caused by the fast breakdown of cancer cells). TLS may cause kidney failure and the need for dialysis treatment. Tell your doctor if you are also receiving cisplatin (Platinol). If you notice that you need to urinate less often than usual or that you produce less urine than usual, tell your doctor immediately.Rituximab has caused severe skin reactions. These reactions have caused death. If you experience any of the following symptoms, tell your doctor immediately: painful sores, ulcers, blisters, rash, or peeling skin.Some people who received rituximab developed progressive multifocal leukoencephalopathy (PML; a rare infection of the brain that cannot be treated, prevented, or cured and that usually causes death or severe disability) during or after their treatment. If you experience any of the following symptoms, call your doctor immediately: difficulty thinking clearly or walking, loss of strength, vision problems, or any other unusual symptoms that develop suddenly.Talk to your doctor about the risks of using rituximab. |
Why is this medication prescribed?
Rituximab is used alone or with other medications to treat certain types of non-Hodgkin's lymphoma (NHL; a type of cancer that begins in a type of white blood cells that normally fights infection). Rituximab is also used with another medication to treat the symptoms of rheumatoid arthritis (RA; a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) in people who have already been treated with a certain type of medication called a tumor necrosis factor (TNF) inhibitor. Rituximab is in a class of medications called biologic antineoplastic agents.It treats NHL by causing the death of blood cells that have multiplied abnormally. It treats rheumatoid arthritis by causing the death of certain blood cells that may cause the immune system to attack the joints.
How should this medicine be used?
Rituximab comes as a solution (liquid) to be injected into a vein. Rituximab is administered by a doctor or nurse in a medical office or infusion center. When rituximab is used to treat rheumatoid arthritis, it is usually given as 2 doses spaced 2 weeks apart. When rituximab is used to treat NHL it is either given once a week for 4-8 weeks or on the first day of each chemotherapy cycle. Your dosing schedule will depend on the condition that you have, the other medications you are using, and how well your body responds to treatment.
Rituximab must be given slowly. It may take several hours or longer to receive your first dose of rituximab, so you should plan to spend most of the day at the medical office or infusion center. After the first dose, you may receive your medication more quickly, depending on how you respond to treatment.
You may experience symptoms such as fever, shaking chills, tiredness, headache, or nausea while you are receiving a dose of rituximab, especially the first dose. Tell your doctor or other healthcare provider if you experience these symptoms while you are receiving your medication. Your doctor may prescribe other medications to help prevent or relieve these symptoms. Your doctor may tell you to take these medications before you receive each dose of rituximab.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before using rituximab,
- tell your doctor and pharmacist if you are allergic to rituximab or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medication in the IMPORTANT WARNING section and either of the following: medications for high blood pressure and other medications for rheumatoid arthritis. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have any of the conditions mentioned in the IMPORTANT WARNING section and if you have or have ever had hepatitis B or other viruses such as chicken pox, herpes (a virus that may cause cold sores or outbreaks of blisters in the genital area), West Nile virus (a virus that is spread through mosquito bites and may cause serious symptoms), or cytomegalovirus (a common virus that usually only causes serious symptoms in people who have weakend immune systems or who are infected at birth). Also tell your doctor if you have any type of infection now or if you have or have ever had an infection that would not go away or an infection that comes and goes.
- tell your doctor if you are pregnant or plan to become pregnant. Rituximab may harm the fetus. You should use birth control to prevent pregnancy during your treatment with rituximab and for up to 12 months after your treatment. Talk to your doctor about types of birth control that will work for you. If you become pregnant while using rituximab, call your doctor.
- tell your doctor if you are breast-feeding.You should not breast-feed during your treatment with rituximab or for some time after your treatment
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using rituximab.
- you should know that you may be drowsy or dizzy after you receive a dose of rituximab. Do not drive a car or operate machinery until you know how this medication affects you. Plan to have someone else drive you home from the medical office or infusion center after you receive your treatment.
- ask your doctor whether you should receive any vaccinations before you begin your treatment with rituximab. Do not have any vaccinations during your treatment without talking to your doctor.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
If you miss an appointment to receive rituximab, call your doctor right away.
What side effects can this medication cause?
Rituximab may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea
- vomiting
- diarrhea
- heartburn
- weight gain
- muscle or back pain
- flushing
- night sweats
- tiredness
- weakness
- numbness, burning or tingling in the hands or feet
- runny nose
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
- stomach area pain
- unusual bruising or bleeding
- sore throat, fever, chills, or other signs of infection
- chest tightness
- joint pain or soreness
Rituximab may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to rituximab.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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