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Savella Side Effects

PatientsVille

Common Savella Side Effects


The most commonly reported Savella side effects (click to view or check a box to report):

Nausea (248)
Headache (165)
Hyperhidrosis (148)
Dizziness (115)
Blood Pressure Increased (110)
Insomnia (104)
Suicidal Ideation (97)
Vomiting (92)
Heart Rate Increased (85)
Hot Flush (81)
Anxiety (78)
Palpitations (70)
Depression (65)
Fatigue (58)
Constipation (54)
Rash (48)
Decreased Appetite (48)
Pain (48)
Tremor (44)
Diarrhoea (42)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Savella Side Effects Reported to FDA



Savella Side Effect Report#9971631
Headache, Dizziness, Insomnia, Vomiting, Dry Mouth
This is a report of a 52-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: fibromyalgia, who was treated with Savella (dosage: 2-week Titration Pack, start time:
Mar 03, 2014), combined with: NA. and developed a serious reaction and side effect(s): Headache, Dizziness, Insomnia, Vomiting, Dry Mouth after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Savella treatment in female patients, resulting in Headache side effect.
Savella Side Effect Report#9969754
Benign Prostatic Hyperplasia, Urinary Incontinence
This report suggests a potential Savella Benign Prostatic Hyperplasia side effect(s) that can have serious consequences. A 59-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: back pain and used Savella (dosage: 25 Mg Twice Daily Twice Daily Taken By Mouth) starting
Jan 08, 2014. After starting Savella the patient began experiencing various side effects, including: Benign Prostatic Hyperplasia, Urinary IncontinenceAdditional drugs used concurrently: NA. Although Savella demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Benign Prostatic Hyperplasia, may still occur.
Savella Side Effect Report#9912567
Blood Pressure Systolic Increased, Blood Pressure Diastolic Increased, Tachycardia
This Blood Pressure Systolic Increased problem was reported by a pharmacist from US. A 51-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: pain,musculoskeletal pain. On
Feb 04, 2014 this consumer started treatment with Savella (dosage: NA). The following drugs were being taken at the same time: NA. When using Savella, the patient experienced the following unwanted symptoms/side effects: Blood Pressure Systolic Increased, Blood Pressure Diastolic Increased, TachycardiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Blood Pressure Systolic Increased, may become evident only after a product is in use by the general population.
Savella Side Effect Report#9858345
Asthenia, Fall, Soft Tissue Disorder, Muscle Disorder, Gastrooesophageal Reflux Disease, Hiatus Hernia, Acquired Oesophageal Web, Palpitations, Heart Rate Increased
This Asthenia side effect was reported by a consumer or non-health professional from US. A 51-year-old female patient (weight:NA) experienced the following symptoms/conditions: pain.The patient was prescribed Savella (drug dosage: Taken By Mouth, One In Am And Pm), which was initiated on NS. Concurrently used drugs: NA..After starting to take Savella the consumer reported adverse symptoms, such as: Asthenia, Fall, Soft Tissue Disorder, Muscle Disorder, Gastrooesophageal Reflux Disease, Hiatus Hernia, Acquired Oesophageal Web, Palpitations, Heart Rate IncreasedThese side effects may potentially be related to Savella. The patient was hospitalized.
Savella Side Effect Report#9820248
Headache, Dizziness, Pain, Fatigue, Asthenia, Hot Flush, Blood Pressure Increased, Chest Pain, Movement Disorder
This is a report of a 43-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: fibromyalgia, who was treated with Savella (dosage: 1/2 Tab X 7days, 1 Tab X7 Days, 1 Tab In Am, start time:
Nov 21, 2013), combined with:
  • Orphendrine
  • Diclofenac
  • Benazepril
  • Omeprazole
  • Lyrica
  • Metoprolol Succer
  • Voltaren
  • Fluticasone Prop
and developed a serious reaction and side effect(s): Headache, Dizziness, Pain, Fatigue, Asthenia, Hot Flush, Blood Pressure Increased, Chest Pain, Movement Disorder after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Savella treatment in female patients, resulting in Headache side effect.
Savella Side Effect Report#9803119
Loss Of Consciousness, Blood Glucose Decreased, Heart Rate Decreased, Respiratory Rate Decreased, Pancreatic Disorder
This report suggests a potential Savella Loss Of Consciousness side effect(s) that can have serious consequences. A 40-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: fibromyalgia and used Savella (dosage: NA) starting
Sep 01, 2012. After starting Savella the patient began experiencing various side effects, including: Loss Of Consciousness, Blood Glucose Decreased, Heart Rate Decreased, Respiratory Rate Decreased, Pancreatic DisorderAdditional drugs used concurrently: NA.The patient was hospitalized. Although Savella demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Loss Of Consciousness, may still occur.
Savella Side Effect Report#9778442
Erythema
This Erythema problem was reported by a consumer or non-health professional from US. A 81-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: neuropathy peripheral. On NS this consumer started treatment with Savella (dosage: NA). The following drugs were being taken at the same time: NA. When using Savella, the patient experienced the following unwanted symptoms/side effects: ErythemaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Erythema, may become evident only after a product is in use by the general population.
Savella Side Effect Report#9770269
Hypersensitivity
This Hypersensitivity side effect was reported by a consumer or non-health professional from US. A 64-year-old female patient (weight:NA) experienced the following symptoms/conditions: fibromyalgia.The patient was prescribed Savella (drug dosage: 12.5 Mg), which was initiated on
Dec 06, 2013. Concurrently used drugs: NA..After starting to take Savella the consumer reported adverse symptoms, such as: HypersensitivityThese side effects may potentially be related to Savella. The patient was hospitalized.
Savella Side Effect Report#9746279
Insomnia, Aggression, Withdrawal Syndrome, Abnormal Behaviour
This is a report of a 63-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: fibromyalgia, who was treated with Savella (dosage: NA, start time:
Sep 18, 2013), combined with: NA. and developed a serious reaction and side effect(s): Insomnia, Aggression, Withdrawal Syndrome, Abnormal Behaviour after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Savella treatment in male patients, resulting in Insomnia side effect.
Savella Side Effect Report#9710881
Amnesia, Hypothyroidism, Genital Hypoaesthesia, Accommodation Disorder
This report suggests a potential Savella Amnesia side effect(s) that can have serious consequences. A 54-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: fibromyalgia and used Savella (dosage: NA) starting NS. After starting Savella the patient began experiencing various side effects, including: Amnesia, Hypothyroidism, Genital Hypoaesthesia, Accommodation DisorderAdditional drugs used concurrently: NA. Although Savella demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Amnesia, may still occur.
Savella Side Effect Report#9528088
Nausea, Off Label Use
This Nausea problem was reported by a consumer or non-health professional from US. A 53-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On
Apr 03, 2012 this consumer started treatment with Savella (dosage: 6.25 Mg (6.25 Mg,1 In 1 D),oral). The following drugs were being taken at the same time:
  • Levoxyl (levothyroxine Sodium) (levothyroxine Sodium)
When using Savella, the patient experienced the following unwanted symptoms/side effects: Nausea, Off Label UseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Nausea, may become evident only after a product is in use by the general population.
Savella Side Effect Report#9528083
Hypoaesthesia, Chills, Nausea, Diarrhoea, Vomiting
This Hypoaesthesia side effect was reported by a consumer or non-health professional from US. A 46-year-old female patient (weight:NA) experienced the following symptoms/conditions: fibromyalgia.The patient was prescribed Savella (drug dosage: 12.5 Mg (12.5 Mg,1 In 1 D)), which was initiated on 2012. Concurrently used drugs: NA..After starting to take Savella the consumer reported adverse symptoms, such as: Hypoaesthesia, Chills, Nausea, Diarrhoea, VomitingThese side effects may potentially be related to Savella.
Savella Side Effect Report#9528043
Decreased Appetite, Hyperhidrosis
This is a report of a 59-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: fibromyalgia, who was treated with Savella (dosage: 12.5 Mg (12.5 Mg,1 In 1 D),oral, start time:
Mar 09, 2012), combined with:
  • Percocet (oxycodone, Acetaminophen) (oxycodone, Acetaminophen)
  • Levothyroxine (levothyroxine Sodium) (levothyroxine Sodium)
  • Protonix (pantoprazole Sodium Sesquihydrate) (pantoprazole Sodium Sesquihydrate)?
  • Abilify (aripiprazole) (aripiprazole)
  • Lexapro (escitalopram Oxalate) (escitalopram Oxalate)
  • Ativan (lorazepam) (lorazepam)
and developed a serious reaction and side effect(s): Decreased Appetite, Hyperhidrosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Savella treatment in female patients, resulting in Decreased Appetite side effect.
Savella Side Effect Report#9528037
Off Label Use
This report suggests a potential Savella Off Label Use side effect(s) that can have serious consequences. A 65-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: fibromyalgia,neuropathy peripheral and used Savella (dosage: NA) starting NS. After starting Savella the patient began experiencing various side effects, including: Off Label UseAdditional drugs used concurrently: NA. Although Savella demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Off Label Use, may still occur.
Savella Side Effect Report#9528030
Diarrhoea, Flatulence
This Diarrhoea problem was reported by a consumer or non-health professional from US. A 57-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: fibromyalgia. On
Mar 09, 2012 this consumer started treatment with Savella (dosage: 12.5 Mg (12.5 Mg,1in 1 D),oral). The following drugs were being taken at the same time:
  • Trandolapril (trandolapril) (trandolapril)
  • Prometrium (progesterone) (progesterone)
  • Cyclobenzaprine (cyclobenzaprine) (cyclobenzaprine)
  • Naproxen (naproxen) (naproxen)
When using Savella, the patient experienced the following unwanted symptoms/side effects: Diarrhoea, FlatulenceAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Diarrhoea, may become evident only after a product is in use by the general population.
Savella Side Effect Report#9528027
Vomiting, Diarrhoea, Headache
This Vomiting side effect was reported by a health professional from US. A 30-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Savella (milnacipran Hydrochloride) (12.5 Milligram, Tablets) (drug dosage: 12.5 Mg (12.5 Mg, 1 In 1 D),oral), which was initiated on
Apr 04, 2011. Concurrently used drugs: NA..After starting to take Savella (milnacipran Hydrochloride) (12.5 Milligram, Tablets) the consumer reported adverse symptoms, such as: Vomiting, Diarrhoea, HeadacheThese side effects may potentially be related to Savella (milnacipran Hydrochloride) (12.5 Milligram, Tablets).
Savella Side Effect Report#9527991
Hot Flush, Blood Pressure Increased, Off Label Use
This is a report of a 53-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: hypertonic bladder, who was treated with Savella (dosage: 12.5 Mg (12.5 Mg,1 In 1 D),oral, start time: 201112), combined with: NA. and developed a serious reaction and side effect(s): Hot Flush, Blood Pressure Increased, Off Label Use after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Savella treatment in female patients, resulting in Hot Flush side effect.
Savella Side Effect Report#9527973
Weight Increased, Off Label Use
This report suggests a potential Savella Weight Increased side effect(s) that can have serious consequences. A 37-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: neuralgia and used Savella (dosage: 12.5 Mg (12.5 Mg,1 In 1 D),oral) starting 201108. After starting Savella the patient began experiencing various side effects, including: Weight Increased, Off Label UseAdditional drugs used concurrently:
  • Oxycontin (oxycodone Hydrochloride) (oxycodone Hydrochrloride)
  • Percocet (oxycodone, Acetaminophen) (oxycodone, Acetaminophen)
  • Xanax (alprazolam) (alprazolam)
  • Prozac (fluoxetine Hydrochloride) Fluoxetine Hydrochloride)
  • Vistaril (hydroxyzine) (hydroxyzine)
  • Piroxicam (piroxicam) (piroxicam)
  • Soma (carisoprodol) (carisoprodol)
  • Ambien (zolpidem Tartrate) (zolpidem Tartrate)
Although Savella demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Weight Increased, may still occur.
Savella Side Effect Report#9527963
Rash
This Rash problem was reported by a consumer or non-health professional from US. A 33-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: trigeminal neuralgia. On
Jan 15, 2012 this consumer started treatment with Savella (dosage: 12.5 Mg (12.5 Mg,1 In 1 D), Oral). The following drugs were being taken at the same time: NA. When using Savella, the patient experienced the following unwanted symptoms/side effects: RashAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Rash, may become evident only after a product is in use by the general population.
Savella Side Effect Report#9527958
Vomiting
This Vomiting side effect was reported by a consumer or non-health professional from US. A 69-year-old female patient (weight:NA) experienced the following symptoms/conditions: fibromyalgia.The patient was prescribed Savella (drug dosage: 12.5 Mg (12.5 Mg,1 In 1 D),oral), which was initiated on
Jan 29, 2012. Concurrently used drugs: NA..After starting to take Savella the consumer reported adverse symptoms, such as: VomitingThese side effects may potentially be related to Savella.
Savella Side Effect Report#9527956
Galactorrhoea
This is a report of a 38-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: fibromyalgia, who was treated with Savella (dosage: 12.5 Mg (12.5 Mg,1 In 1 D), Oral, start time:
Feb 02, 2012), combined with:
  • Nuvigil (armodafinil) (armodafinil)
  • Protonix (pantoprazole Sodium Sesquithydrate) (pantoprazole Sodium Sesquihydrate)
and developed a serious reaction and side effect(s): Galactorrhoea after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Savella treatment in female patients, resulting in Galactorrhoea side effect.
Savella Side Effect Report#9527953
Blood Pressure Increased
This report suggests a potential Savella Blood Pressure Increased side effect(s) that can have serious consequences. A 44-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: fibromyalgia and used Savella (dosage: NA) starting 2011. After starting Savella the patient began experiencing various side effects, including: Blood Pressure IncreasedAdditional drugs used concurrently:
  • Flonase (fluticasone Propionate)
  • Ranitidine (ranitidine (ranitidine)
Although Savella demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Blood Pressure Increased, may still occur.
Savella Side Effect Report#9527952
Hot Flush
This Hot Flush problem was reported by a consumer or non-health professional from US. A 49-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: fibromyalgia. On NS this consumer started treatment with Savella (dosage: NA). The following drugs were being taken at the same time:
  • Flexeril (cyclobenzaprine) (cyclobenzaprine)
When using Savella, the patient experienced the following unwanted symptoms/side effects: Hot FlushAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hot Flush, may become evident only after a product is in use by the general population.
Savella Side Effect Report#9527941
Nausea
This Nausea side effect was reported by a consumer or non-health professional from US. A 61-year-old female patient (weight:NA) experienced the following symptoms/conditions: fibromyalgia.The patient was prescribed Savella (drug dosage: NA), which was initiated on
Jan 24, 2012. Concurrently used drugs:
  • Synthroid (levothyroxine)
  • Proair Hfa (salbutamol Sulfate) (salbutamol Sulfate)
  • Tramadol (tramadol) (tramadol)
  • Nexium (esomeprazole) (esomeprazole)
  • Lovastatin (lovastatin) (lovastatin)
  • Elmiron
.After starting to take Savella the consumer reported adverse symptoms, such as: NauseaThese side effects may potentially be related to Savella.
Savella Side Effect Report#9527937
Peripheral Coldness, Feeling Cold, Dysuria, Urinary Incontinence
This is a report of a 47-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: fibromyalgia, who was treated with Savella (dosage: NA, start time: 201110), combined with: NA. and developed a serious reaction and side effect(s): Peripheral Coldness, Feeling Cold, Dysuria, Urinary Incontinence after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Savella treatment in male patients, resulting in Peripheral Coldness side effect.


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The appearance of Savella on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Savella Side Effects for Women?

Women Side EffectsReports
Nausea 233
Headache 157
Hyperhidrosis 140
Dizziness 108
Blood Pressure Increased 104
Insomnia 91
Suicidal Ideation 86
Vomiting 82
Hot Flush 77
Anxiety 74

What are common Savella Side Effects for Men?

Men Side EffectsReports
Urinary Retention 18
Dysuria 16
Nausea 13
Insomnia 12
Heart Rate Increased 11
Suicidal Ideation 10
Agitation 8
Headache 8
Hyperhidrosis 8
Vomiting 8

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Savella reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Savella Side Effects

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    How Effective is Savella for You?

    Exceeded Expectations
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    Savella Safety Alerts, Active Ingredients, Usage Information

    NDC0456-1500
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameSavella
    Namemilnacipran hydrochloride
    Dosage FormKIT
    RouteORAL
    On market since20090417
    LabelerForest Laboratories, Inc.
    Active Ingredient(s)
    Strength(s)
    Unit(s)
    Pharma Class

    More About Savella

    Side Effects reported to FDA: 1293

    Savella safety alerts: No

    Reported deaths: 14

    Reported hospitalizations: 164

    Latest Savella clinical trials