SEVOFLURANE Side Effects

6683033-4 | Grand Mal Convulsion
on Apr 07, 2010 Female patient from TUNISIA , child 8 years of age, was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: grand mal convulsion. Sevoflurane dosage: .

6681970-8 | Blood Pressure Increased, Lacrimation Increased, Unwanted Awareness During Anaesthesia
Patient was taking Sevoflurane (View Usage). Patient had the following side effects: blood pressure increased, lacrimation increased, unwanted awareness during anaesthesia on Apr 05, 2010 from PHILIPPINES Additional patient health information: Female patient , 52 years of age, weighting 143.3 lb, . Sevoflurane dosage: . During the same period patient was treated with FENTANYL (View Fentanyl Review and Fentanyl Label ).

6681060-4 | Anaphylactic Shock, Bradycardia, Bronchospasm, Eyelid Oedema, Rash, Ventricular Tachycardia
Adverse event was reported on Apr 06, 2010 by a Female patient taking Sevoflurane (View Usage) (Dosage: Once) was diagnosed with anaesthesia, sedation and. Location: FRANCE , 34 years of age, After Sevoflurane was administered, patient had the following side effects: anaphylactic shock, bradycardia, bronchospasm, eyelid oedema, rash (What is rash?), ventricular tachycardia. During the same period patient was treated with CELOCURINE (View Celocurine Review and Celocurine Label ), ETOMIDATE (View Etomidate Review and Etomidate Label ), RAPIFEN (View Rapifen Review and Rapifen Label ), NEXIUM (View Nexium Review and Nexium Label ), PERFALGAN (View Perfalgan Review and Perfalgan Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), AUGMENTIN '125' (View Augmentin '125' Review and Augmentin '125' Label ), DUPHALAC (View Duphalac Review and Duphalac Label ). Patient was hospitalized.

6673662-6 | Aspiration, Cardiac Failure, Circulatory Collapse, Ejection Fraction Decreased, Respiratory Distress
on Mar 29, 2010 Female patient from FRANCE , 20 years of age, was diagnosed with anaesthesia and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: aspiration, cardiac failure, circulatory collapse, ejection fraction decreased, respiratory distress. Sevoflurane dosage: Once. During the same period patient was treated with CEFALOTINE (View Cefalotine Review and Cefalotine Label ), MIDAZOLAM HCL (View Midazolam Hcl Review and Midazolam Hcl Label ), PROPOFOL (View Propofol Review and Propofol Label ), FENTANYL (View Fentanyl Review and Fentanyl Label ), DOPRAM (View Dopram Review and Dopram Label ), ADRENALIN (View Adrenalin Review and Adrenalin Label ), TROPONINE (Dose Decreased) (View Troponine Review and Troponine Label ). Patient was hospitalized.


6663745-9 | Blood Potassium Increased, Hyperthermia Malignant, Operative Haemorrhage, Oxygen Saturation Decreased
on Mar 24, 2010 Male patient from CHINA , 25 years of age, weighting 103.6 lb, was diagnosed with anaesthesia and was treated with Sevoflurane (View Usage). Patient had the following side effects: blood potassium increased, hyperthermia malignant, operative haemorrhage, oxygen saturation decreased. Sevoflurane dosage: 1%, 1 L/min. During the same period patient was treated with VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ), NITROUS OXIDE (View Nitrous Oxide Review and Nitrous Oxide Label ). Patient was hospitalized.

6662173-X | Hepatic Failure, Hepatitis Acute
Patient was taking Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: hepatic failure, hepatitis acute on Mar 24, 2010 from AUSTRALIA Additional patient health information: Male patient , child 6 years of age, . Sevoflurane dosage: . During the same period patient was treated with NITROUS OXIDE (View Nitrous Oxide Review and Nitrous Oxide Label ), OXYGEN (View Oxygen Review and Oxygen Label ), PARACETAMOL (View Paracetamol Review and Paracetamol Label ), FENTANYL CITRATE (View Fentanyl Citrate Review and Fentanyl Citrate Label ), MIDAZOLAM HCL (View Midazolam Hcl Review and Midazolam Hcl Label ). Patient was hospitalized.

6656818-8 | Electrocardiogram Qt Prolonged, Ventricular Extrasystoles, Ventricular Tachycardia
Adverse event was reported on Mar 18, 2010 by a Female patient taking Sevoflurane (View Usage) (Dosage: 1%x14hrsx6l/min) was diagnosed with endotracheal intubation, anaesthesia, labile hypertension and. Location: JAPAN , weighting 94.80 lb, Patient experienced the following unwanted or unexpected effects: electrocardiogram qt prolonged, ventricular extrasystoles, ventricular tachycardia. During the same period patient was treated with ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), REMIFENTANIL HYDROCHLORIDE (View Remifentanil Hydrochloride Review and Remifentanil Hydrochloride Label ), DOPAMINE HYDROCHLORIDE (12 Microliter/hr) (View Dopamine Hydrochloride Review and Dopamine Hydrochloride Label ).

6656763-8 | Electrocardiogram Qt Prolonged, Torsade De Pointes
on Mar 18, 2010 Female patient from JAPAN , 59 years of age, was diagnosed with anaesthesia, blood pressure management, endotracheal intubation and was treated with Sevoflurane (View Usage). Patient had the following side effects: electrocardiogram qt prolonged, torsade de pointes. Sevoflurane dosage: . During the same period patient was treated with DOPAMINE HCL (View Dopamine Hcl Review and Dopamine Hcl Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), REMIFENTANIL (View Remifentanil Review and Remifentanil Label ).

6646940-4 | Cardiac Arrest, Cardiac Failure, Ventricular Fibrillation
on Mar 11, 2010 Female patient from FRANCE , 28 years of age, was diagnosed with juvenile arthritis and was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: cardiac arrest (What is cardiac arrest?), cardiac failure, ventricular fibrillation. Sevoflurane dosage: . During the same period patient was treated with HYDROXYZINE (View Hydroxyzine Review and Hydroxyzine Label ), DIPRIVAN (View Diprivan Review and Diprivan Label ).

6646939-8 | Cardiac Failure, Pulmonary Oedema
Patient was taking Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: cardiac failure, pulmonary oedema on Mar 11, 2010 from FRANCE Additional patient health information: Female patient , 21 years of age, was diagnosed with juvenile arthritis and. Sevoflurane dosage: . During the same period patient was treated with HYDROXYZINE (View Hydroxyzine Review and Hydroxyzine Label ), DIPRIVAN (View Diprivan Review and Diprivan Label ).

6642687-9 | Anaphylactic Shock, Bradycardia, Bronchospasm, Eyelid Oedema, Rash, Ventricular Tachycardia
Adverse event was reported on Mar 10, 2010 by a Female patient taking Sevoflurane (View Usage) (Dosage: Once) was diagnosed with anaesthesia, sedation and. Location: FRANCE , 34 years of age, Patient had the following side effects: anaphylactic shock, bradycardia, bronchospasm, eyelid oedema, rash (What is rash?), ventricular tachycardia. During the same period patient was treated with CELOCURINE (View Celocurine Review and Celocurine Label ), ETOMIDATE (View Etomidate Review and Etomidate Label ), RAPIFEN (View Rapifen Review and Rapifen Label ), NEXIUM (View Nexium Review and Nexium Label ), PERFALGAN (View Perfalgan Review and Perfalgan Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), AUGMENTIN (View Augmentin Review and Augmentin Label ), DUPHALAC (View Duphalac Review and Duphalac Label ). Patient was hospitalized.

6636735-X | Electrocardiogram Qt Prolonged, Torsade De Pointes
on Mar 10, 2010 Female patient from JAPAN , 59 years of age, was diagnosed with anaesthesia and was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: electrocardiogram qt prolonged, torsade de pointes. Sevoflurane dosage: . During the same period patient was treated with HYDROCHLORIC ACID PAROXETINE (View Hydrochloric Acid Paroxetine Review and Hydrochloric Acid Paroxetine Label ).

6631201-X | Hepatic Failure
on Feb 22, 2010 Female patient from SLOVENIA , 66 years of age, was diagnosed with biopsy lymph gland, mastectomy (What is mastectomy?) and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: hepatic failure. Sevoflurane dosage: 1l/min, Once, Inhalation. During the same period patient was treated with PROPOFOL (View Propofol Review and Propofol Label ), SUFENTANIL (View Sufentanil Review and Sufentanil Label ).

6631116-7 | Anaesthetic Complication, Muscle Rigidity, Pyrexia
Patient was taking Sevoflurane (View Usage). Patient had the following side effects: anaesthetic complication, muscle rigidity, pyrexia on Feb 22, 2010 from UNITED STATES Additional patient health information: Male patient , 30 years of age, weighting 205.0 lb, was diagnosed with fasciotomy, debridement and. Sevoflurane dosage: 2.4% Once, Inhalation. During the same period patient was treated with ISOFLURANE (2%, Once, Inhalation) (View Isoflurane Review and Isoflurane Label ), MIDOZOLAM (View Midozolam Review and Midozolam Label ), FENTANYL (View Fentanyl Review and Fentanyl Label ), LIDOCAINE (View Lidocaine Review and Lidocaine Label ), PROPOFOL (View Propofol Review and Propofol Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), SUCCINYLCHOLINE CHLORIDE (View Succinylcholine Chloride Review and Succinylcholine Chloride Label ). Patient was hospitalized.

6631047-2 | Bundle Branch Block, Sinus Bradycardia
Adverse event was reported on Mar 03, 2010 by a Female patient taking Sevoflurane (View Usage) (Dosage: 2.9-6.2 Insp. 2.8-6.3 Expir.) was diagnosed with hernia repair, induction of anaesthesia, maintenance of anaesthesia and. Location: AUSTRIA , weighting 5.07 lb, After Sevoflurane was administered, patient had the following side effects: bundle branch block, sinus bradycardia. During the same period patient was treated with PROPOFOL (View Propofol Review and Propofol Label ), FENTANYL (View Fentanyl Review and Fentanyl Label ), N2O/O2 (50:50) (View N2o/o2 Review and N2o/o2 Label ), NAROPIN (2 Ml (0.2%) Single Shot) (View Naropin Review and Naropin Label ).

6630861-7 | Electrocardiogram Qt Prolonged, Torsade De Pointes
on Mar 03, 2010 Female patient from JAPAN , 59 years of age, was diagnosed with anaesthesia and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: electrocardiogram qt prolonged, torsade de pointes. Sevoflurane dosage: . During the same period patient was treated with HYDROCHLORIC ACID PAROXETINE (View Hydrochloric Acid Paroxetine Review and Hydrochloric Acid Paroxetine Label ).

6614345-8 | Overdose
on Feb 23, 2010 Female patient from NEW ZEALAND , weighting 166.4 lb, was treated with Sevoflurane (View Usage). Patient had the following side effects: overdose. Sevoflurane dosage: . During the same period patient was treated with NUROFEN (View Nurofen Review and Nurofen Label ), ACETAMINOPHEN AND CODEINE PHOSPHATE (View Acetaminophen And Codeine Phosphate Review and Acetaminophen And Codeine Phosphate Label ), LOSEC (View Losec Review and Losec Label ), FERROUS SULFATE TAB (View Ferrous Sulfate Tab Review and Ferrous Sulfate Tab Label ), PAIN KILLERS (View Pain Killers Review and Pain Killers Label ).

6610202-1 | Cerebral Ischaemia, Delirium, Loss Of Consciousness, Vomiting
Patient was taking Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: cerebral ischaemia, delirium, loss of consciousness, vomiting on Feb 24, 2010 from CHINA Additional patient health information: Male patient , weighting 132.3 lb, . Sevoflurane dosage: 2 % With Gas Speed 2 L/min.

6609155-1 | Blood Pressure Decreased, Tachycardia
Adverse event was reported on Feb 18, 2010 by a Female patient taking Sevoflurane (View Usage) (Dosage: ) . Location: JAPAN , weighting 116.8 lb, Patient experienced the following unwanted or unexpected effects: blood pressure decreased, tachycardia. During the same period patient was treated with NITROUS OXIDE (50% 3l/min @ 14:53) (View Nitrous Oxide Review and Nitrous Oxide Label ), ISOZOL (@ 14:53) (View Isozol Review and Isozol Label ), SUCCINYLCHOLINE CHLORIDE (@ 14:53) (View Succinylcholine Chloride Review and Succinylcholine Chloride Label ), MUSCULAX (@ 14:53) (View Musculax Review and Musculax Label ).

6602745-1 | Hypersensitivity, Hyperthermia Malignant, Hypoxia, Jaundice, Platelet Count Decreased, Renal Failure Acute
on Feb 17, 2010 Female patient from JAPAN , weighting 110.2 lb, was diagnosed with infection prophylaxis and was treated with Sevoflurane (View Usage). Patient had the following side effects: hypersensitivity, hyperthermia malignant, hypoxia, jaundice (What is jaundice?), platelet count decreased, renal failure acute. Sevoflurane dosage: Dose:1-3%, Total Administration:70 Ml.. During the same period patient was treated with FENTANYL CITRATE (View Fentanyl Citrate Review and Fentanyl Citrate Label ), CEFAMEZIN (View Cefamezin Review and Cefamezin Label ), L ASPARTATE POTASSIUM (View L-aspartate Potassium Review and L-aspartate Potassium Label ), ADONA (View Adona Review and Adona Label ), ANCOMA (View Ancoma Review and Ancoma Label ), INOVAN (View Inovan Review and Inovan Label ), CALCICOL (View Calcicol Review and Calcicol Label ), XYLOCAINE (View Xylocaine Review and Xylocaine Label ).

6601489-X | Cerebral Disorder, Convulsion, Dystonia, Extrapyramidal Disorder, Hypersensitivity, No Therapeutic Response, Oculogyric Crisis, Pruritus, Rash Macular
on Feb 15, 2010 Female patient from UNITED KINGDOM , 22 years of age, was diagnosed with postoperative analgesia, anaesthesia, pain management and was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: cerebral disorder, convulsion, dystonia (What is dystonia?), extrapyramidal disorder, hypersensitivity, no therapeutic response, oculogyric crisis, pruritus, rash macular. Sevoflurane dosage: . During the same period patient was treated with ONDANSETRON (View Ondansetron Review and Ondansetron Label ), PROPOFOL (View Propofol Review and Propofol Label ), DIAMORPHINE (View Diamorphine Review and Diamorphine Label ), SULFASALAZINE (View Sulfasalazine Review and Sulfasalazine Label ), KETOROLAC TROMETHAMINE (View Ketorolac Tromethamine Review and Ketorolac Tromethamine Label ). Patient was hospitalized.

6601122-7 | Cardiac Arrest, Long Qt Syndrome
Patient was taking Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: cardiac arrest (What is cardiac arrest?), long qt syndrome on Feb 15, 2010 from UNITED KINGDOM Additional patient health information: Female patient , 35 years of age, was diagnosed with maintenance of anaesthesia, hypotension, induction of anaesthesia and. Sevoflurane dosage: 2-3%. During the same period patient was treated with LIDOCAINE (2%) (View Lidocaine Review and Lidocaine Label ), EPINEPHRINE (View Epinephrine Review and Epinephrine Label ), ONDANSETRON (View Ondansetron Review and Ondansetron Label ), COCAINE (View Cocaine Review and Cocaine Label ), AMIODARONE HCL (View Amiodarone Hcl Review and Amiodarone Hcl Label ), SODIUM BICARBONATE (View Sodium Bicarbonate Review and Sodium Bicarbonate Label ), DICLOFENAC (View Diclofenac Review and Diclofenac Label ), PROPOFOL (View Propofol Review and Propofol Label ). Patient was hospitalized.

6600060-3 | Anaphylactic Shock, Blood Pressure Decreased, Epiglottic Oedema, Laryngeal Oedema, Obstructive Airways Disorder
Adverse event was reported on Feb 15, 2010 by a Male patient taking Sevoflurane (View Usage) (Dosage: 4-2% For 60minuits) was diagnosed with surgery (What is surgery?), induction of anaesthesia and. Location: JAPAN , weighting 136.7 lb, Patient had the following side effects: anaphylactic shock, blood pressure decreased, epiglottic oedema, laryngeal oedema, obstructive airways disorder. During the same period patient was treated with MUSCULAX (View Musculax Review and Musculax Label ), LIDOCAINE (View Lidocaine Review and Lidocaine Label ), PROPOFOL (View Propofol Review and Propofol Label ), ATROPINE SULFATE (View Atropine Sulfate Review and Atropine Sulfate Label ), ATARAX (View Atarax Review and Atarax Label ), CEFAMEZIN (View Cefamezin Review and Cefamezin Label ), NITROUS OXIDE (4 L/minuits) (View Nitrous Oxide Review and Nitrous Oxide Label ). Patient was hospitalized.

6558305-4 | Cerebral Ischaemia, Delirium, Loss Of Consciousness
on Jan 27, 2010 Male patient from CHINA , 80 years of age, was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: cerebral ischaemia, delirium, loss of consciousness. Sevoflurane dosage: .

6557806-2 | Hypersensitivity, Hyperthermia Malignant, Hypoxia, Jaundice, Platelet Count Decreased, Renal Failure Acute
on Jan 25, 2010 Female patient from JAPAN , weighting 110.2 lb, was diagnosed with infection prophylaxis and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: hypersensitivity, hyperthermia malignant, hypoxia, jaundice (What is jaundice?), platelet count decreased, renal failure acute. Sevoflurane dosage: Dose:1-3%, Total Administration:70 Ml.. During the same period patient was treated with FENTANYL CITRATE (View Fentanyl Citrate Review and Fentanyl Citrate Label ), CEFAMEZIN (View Cefamezin Review and Cefamezin Label ), L ASPARTATE POTASSIUM (View L-aspartate Potassium Review and L-aspartate Potassium Label ), ADONA (View Adona Review and Adona Label ), ANCOMA (View Ancoma Review and Ancoma Label ), INOVAN (View Inovan Review and Inovan Label ), CALCICOL (View Calcicol Review and Calcicol Label ), XYLOCAINE (View Xylocaine Review and Xylocaine Label ).

6544836-X | Bronchospasm, Pulmonary Oedema, Rhabdomyolysis, Wheezing
Patient was taking Sevoflurane (View Usage). Patient had the following side effects: bronchospasm, pulmonary oedema, rhabdomyolysis, wheezing on Jan 12, 2010 from UNITED STATES Additional patient health information: Female patient , 52 years of age, weighting 280.0 lb, was diagnosed with induction of anaesthesia and. Sevoflurane dosage: . During the same period patient was treated with ATENOLOL (View Atenolol Review and Atenolol Label ), HYDROCHLOROTHIAZIDE (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ), FERROUS SULFATE TAB (View Ferrous Sulfate Tab Review and Ferrous Sulfate Tab Label ), POTASSIUM CHLORIDE (View Potassium Chloride Review and Potassium Chloride Label ), MELOXICAM (View Meloxicam Review and Meloxicam Label ), ASPIRIN (View Aspirin Review and Aspirin Label ). Patient was hospitalized.

6544789-4 | Blood Pressure Decreased, Epiglottic Oedema, Laryngeal Oedema, Obstructive Airways Disorder
Adverse event was reported on Jan 12, 2010 by a Male patient taking Sevoflurane (View Usage) (Dosage: 4-2% For 60 Minuits) was diagnosed with surgery (What is surgery?) and. Location: JAPAN , weighting 136.7 lb, After Sevoflurane was administered, patient had the following side effects: blood pressure decreased, epiglottic oedema, laryngeal oedema, obstructive airways disorder. During the same period patient was treated with VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ), XYLOCAINE E INJ (View Xylocaine E Inj Review and Xylocaine E Inj Label ), DIPRIVAN (View Diprivan Review and Diprivan Label ), ATROPINE SULFATE (View Atropine Sulfate Review and Atropine Sulfate Label ), ATARAX (View Atarax Review and Atarax Label ).

6527612-3 | Blood Pressure Decreased, Epiglottic Oedema, Laryngeal Oedema, Obstructive Airways Disorder
on Dec 24, 2009 Male patient from JAPAN , weighting 136.7 lb, was diagnosed with surgery (What is surgery?) and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: blood pressure decreased, epiglottic oedema, laryngeal oedema, obstructive airways disorder. Sevoflurane dosage: 4-2% For 60 Minuits. During the same period patient was treated with VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ), XYLOCAINE E INJ (View Xylocaine E Inj Review and Xylocaine E Inj Label ), DIPRIVAN (View Diprivan Review and Diprivan Label ), ATROPINE SULFATE (View Atropine Sulfate Review and Atropine Sulfate Label ), ATARAX (View Atarax Review and Atarax Label ).

6521012-8 | Torsade De Pointes, Ventricular Extrasystoles
on Dec 22, 2009 Female patient from JAPAN , 13 years of age, was diagnosed with maintenance of anaesthesia, induction of anaesthesia and was treated with Sevoflurane (View Usage). Patient had the following side effects: torsade de pointes, ventricular extrasystoles. Sevoflurane dosage: . During the same period patient was treated with THIOPENTAL SODIUM (View Thiopental Sodium Review and Thiopental Sodium Label ), VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ), NITROUS OXIDE (View Nitrous Oxide Review and Nitrous Oxide Label ).

6520108-4 | Blood Pressure Decreased, Epiglottic Oedema, Laryngeal Oedema, Obstructive Airways Disorder
Patient was taking Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: blood pressure decreased, epiglottic oedema, laryngeal oedema, obstructive airways disorder on Dec 28, 2009 from JAPAN Additional patient health information: Male patient , weighting 136.7 lb, was diagnosed with surgery (What is surgery?) and. Sevoflurane dosage: 4-2% For 60 Minuits. During the same period patient was treated with VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ), XYLOCAINE E INJ (View Xylocaine E Inj Review and Xylocaine E Inj Label ), DIPRIVAN (View Diprivan Review and Diprivan Label ), ATROPINE SULFATE (View Atropine Sulfate Review and Atropine Sulfate Label ), ATARAX (View Atarax Review and Atarax Label ).

6516078-5 | Blood Pressure Decreased, Epiglottic Oedema, Laryngeal Oedema, Obstructive Airways Disorder
Adverse event was reported on Dec 16, 2009 by a Male patient taking Sevoflurane (View Usage) (Dosage: 4-2% For 60 Minuits) was diagnosed with surgery (What is surgery?) and. Location: JAPAN , weighting 136.7 lb, Patient experienced the following unwanted or unexpected effects: blood pressure decreased, epiglottic oedema, laryngeal oedema, obstructive airways disorder. During the same period patient was treated with VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ), XYLOCAINE E INJ (View Xylocaine E Inj Review and Xylocaine E Inj Label ), DIPRIVAN (View Diprivan Review and Diprivan Label ), ATROPINE SULFATE (View Atropine Sulfate Review and Atropine Sulfate Label ), ATARAX (View Atarax Review and Atarax Label ).

6515750-0 | Blood Pressure Decreased, Electrocardiogram St Segment Elevation, Ventricular Tachycardia
on Dec 16, 2009 Male patient from JAPAN , weighting 143.3 lb, was diagnosed with induction and maintenance of anaesthesia, induction of anaesthesia, local anaesthesia and was treated with Sevoflurane (View Usage). Patient had the following side effects: blood pressure decreased, electrocardiogram st segment elevation, ventricular tachycardia. Sevoflurane dosage: 5 %/ 1.0 - 1.5 %. During the same period patient was treated with FENTANYL 100 (View Fentanyl-100 Review and Fentanyl-100 Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), PROPOFOL (View Propofol Review and Propofol Label ), FLURBIPROFEN (View Flurbiprofen Review and Flurbiprofen Label ), XYLOCAINE W/ EPINEPHRINE (View Xylocaine W/ Epinephrine Review and Xylocaine W/ Epinephrine Label ), OXYGEN (View Oxygen Review and Oxygen Label ), HEPARIN (View Heparin Review and Heparin Label ).

6509064-2 | Subacute Hepatic Failure
on Dec 17, 2009 Female patient from SLOVENIA , 66 years of age, was diagnosed with induction of anaesthesia, endotracheal intubation, maintenance of anaesthesia and was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: subacute hepatic failure. Sevoflurane dosage: . During the same period patient was treated with PROPOFOL (View Propofol Review and Propofol Label ), SUFENTANIL CITRATE (View Sufentanil Citrate Review and Sufentanil Citrate Label ), PANCURONIUM BROMIDE (View Pancuronium Bromide Review and Pancuronium Bromide Label ), OXYGEN (View Oxygen Review and Oxygen Label ). Patient was hospitalized.

6503081-4 | Deep Vein Thrombosis, Grand Mal Convulsion, Hypothermia, Metabolic Acidosis, Status Epilepticus, Unresponsive To Stimuli
Patient was taking Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: deep vein thrombosis (What is deep vein thrombosis?), grand mal convulsion, hypothermia (What is hypothermia?), metabolic acidosis, status epilepticus, unresponsive to stimuli on Dec 09, 2009 from GERMANY Additional patient health information: Male patient , weighting 8.82 lb, was diagnosed with stupor, cleft lip repair, hypotonia, antibiotic prophylaxis and. Sevoflurane dosage: . During the same period patient was treated with ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), SUFENTANIL CITRATE (View Sufentanil Citrate Review and Sufentanil Citrate Label ), CEFUROXIME (View Cefuroxime Review and Cefuroxime Label ), ZYMAFLUOR CALCIUM (View Zymafluor Calcium Review and Zymafluor Calcium Label ). Patient was hospitalized.

6499122-3 | Pulmonary Oedema
Adverse event was reported on Dec 07, 2009 by a Female patient taking Sevoflurane (View Usage) (Dosage: 4.0-1.0 Percent) was diagnosed with hypertension, hypokalaemia, hyperglycaemia, diabetes mellitus, anaesthesia, hypotonia and. Location: JAPAN , weighting 88.18 lb, Patient had the following side effects: pulmonary oedema. During the same period patient was treated with ALDOMET (View Aldomet Review and Aldomet Label ), SLOW K (View Slow-k Review and Slow-k Label ), INSULIN ASPART (View Insulin Aspart Review and Insulin Aspart Label ), ULTIVA (View Ultiva Review and Ultiva Label ), THIOPENTAL SODIUM (View Thiopental Sodium Review and Thiopental Sodium Label ), MUSCURATE (View Muscurate Review and Muscurate Label ), ANAPEINE (View Anapeine Review and Anapeine Label ). Patient was hospitalized.

6498869-2 | Laryngeal Oedema
on Dec 15, 2009 Female patient from POLAND , weighting 36.82 lb, was diagnosed with anaesthesia, nuclear magnetic resonance imaging, tuberous sclerosis (What is tuberous sclerosis?) and was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: laryngeal oedema. Sevoflurane dosage: . During the same period patient was treated with ISOFLURANE (View Isoflurane Review and Isoflurane Label ), NITROUS OXIDE (View Nitrous Oxide Review and Nitrous Oxide Label ).

6491441-X | Bundle Branch Block
on Dec 03, 2009 Female patient from JAPAN , 17 years of age, was diagnosed with maintenance of anaesthesia, induction of anaesthesia and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: bundle branch block. Sevoflurane dosage: . During the same period patient was treated with REMIFENTANIL (View Remifentanil Review and Remifentanil Label ), PROPOFOL (View Propofol Review and Propofol Label ), VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ).

6490365-1 | Dystonia, Myotonia, Sinus Tachycardia
Patient was taking Sevoflurane (View Usage). Patient had the following side effects: dystonia (What is dystonia?), myotonia, sinus tachycardia on Dec 03, 2009 from UNITED KINGDOM Additional patient health information: Female patient , 55 years of age, weighting 132.3 lb, was diagnosed with maintenance of anaesthesia, musculoskeletal pain, neuralgia and. Sevoflurane dosage: Not Reported. During the same period patient was treated with ISOFLURANE (0.9-1.4%) (View Isoflurane Review and Isoflurane Label ), DEXAMETHASONE TAB (View Dexamethasone Tab Review and Dexamethasone Tab Label ), GABAPENTIN (View Gabapentin Review and Gabapentin Label ). Patient was hospitalized.

6489616-9 | Laryngeal Oedema
Adverse event was reported on Dec 04, 2009 by a Female patient taking Sevoflurane (View Usage) (Dosage: ) was diagnosed with anaesthesia, tuberous sclerosis (What is tuberous sclerosis?) and. Location: POLAND , weighting 36.82 lb, After Sevoflurane was administered, patient had the following side effects: laryngeal oedema. During the same period patient was treated with ISOFLURANE (View Isoflurane Review and Isoflurane Label ), NITROUS OXIDE (View Nitrous Oxide Review and Nitrous Oxide Label ).

6486916-3 | Cardiac Arrest, Long Qt Syndrome
on Dec 02, 2009 Female patient from UNITED KINGDOM , 35 years of age, was diagnosed with maintenance of anaesthesia, hypotension and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: cardiac arrest (What is cardiac arrest?), long qt syndrome. Sevoflurane dosage: 2-3%. During the same period patient was treated with LIDOCAINE (2%) (View Lidocaine Review and Lidocaine Label ), EPINEPHRINE (View Epinephrine Review and Epinephrine Label ), ONDANSETRON (View Ondansetron Review and Ondansetron Label ), COCAINE (View Cocaine Review and Cocaine Label ), AMIODARONE HCL (View Amiodarone Hcl Review and Amiodarone Hcl Label ), OXYGEN (Not Reported) (View Oxygen Review and Oxygen Label ), SODIUM BICARBONATE IN PLASTIC CONTAINER (View Sodium Bicarbonate In Plastic Container Review and Sodium Bicarbonate In Plastic Container Label ), DICLOFENAC (View Diclofenac Review and Diclofenac Label ). Patient was hospitalized.

6486915-1 | Angina Pectoris, Arteriosclerosis Coronary Artery, Arteriospasm Coronary, Blood Pressure Decreased, Electrocardiogram St Segment Elevation, Ventricular Tachycardia
on Nov 30, 2009 Male patient from JAPAN , weighting 143.3 lb, was diagnosed with induction and maintenance of anaesthesia, induction of anaesthesia, local anaesthesia and was treated with Sevoflurane (View Usage). Patient had the following side effects: angina pectoris, arteriosclerosis coronary artery, arteriospasm coronary, blood pressure decreased, electrocardiogram st segment elevation, ventricular tachycardia. Sevoflurane dosage: 5 %/ 1.0 - 1.5 %. During the same period patient was treated with FENTANYL (View Fentanyl Review and Fentanyl Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), PROPOFOL (View Propofol Review and Propofol Label ), FLURBIPROFEN (View Flurbiprofen Review and Flurbiprofen Label ), XYLOCAINE W/ EPINEPHRINE (View Xylocaine W/ Epinephrine Review and Xylocaine W/ Epinephrine Label ), OXYGEN (View Oxygen Review and Oxygen Label ), HEPARIN (View Heparin Review and Heparin Label ).

6484309-6 | Intracranial Pressure Increased
Patient was taking Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: intracranial pressure increased on Dec 03, 2009 from JAPAN Additional patient health information: Female patient , weighting 15.21 lb, was diagnosed with maintenance of anaesthesia, induction of anaesthesia, hypotonia and. Sevoflurane dosage: 2%-5%. During the same period patient was treated with THIAMYLAL SODIUM (View Thiamylal Sodium Review and Thiamylal Sodium Label ), PROPOFOL (View Propofol Review and Propofol Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), MIDAZOLAM HCL (View Midazolam Hcl Review and Midazolam Hcl Label ), ATROPINE SULFATE (View Atropine Sulfate Review and Atropine Sulfate Label ).

6480497-6 | Status Epilepticus
Adverse event was reported on Nov 30, 2009 by a Female patient taking Sevoflurane (View Usage) (Dosage: 1.2 - 1.5%) was diagnosed with maintenance of anaesthesia, epilepsy (What is epilepsy?), induction of anaesthesia, endotracheal intubation and. Location: JAPAN , weighting 105.8 lb, Patient experienced the following unwanted or unexpected effects: status epilepticus. During the same period patient was treated with PHENYTOIN (View Phenytoin Review and Phenytoin Label ), BEPOTASTINE BESILATE (View Bepotastine Besilate Review and Bepotastine Besilate Label ), PROPOFOL (View Propofol Review and Propofol Label ), FENTANYL (View Fentanyl Review and Fentanyl Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), OXYGEN (View Oxygen Review and Oxygen Label ), REMIFENTANIL (0.1 - 0.2 Mcg/kg/min) (View Remifentanil Review and Remifentanil Label ).

6474045-4 | Intracranial Pressure Increased
on Nov 24, 2009 Female patient from JAPAN , weighting 15.21 lb, was diagnosed with induction of anaesthesia, hypotonia, maintenance of anaesthesia and was treated with Sevoflurane (View Usage). Patient had the following side effects: intracranial pressure increased. Sevoflurane dosage: 2%. During the same period patient was treated with THIAMYLAL SODIUM (View Thiamylal Sodium Review and Thiamylal Sodium Label ), PROPOFOL (View Propofol Review and Propofol Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), MIDAZOLAM HCL (View Midazolam Hcl Review and Midazolam Hcl Label ), ATROPINE SULFATE (View Atropine Sulfate Review and Atropine Sulfate Label ).

6472164-X | Epilepsy
on Nov 27, 2009 Female patient from JAPAN , weighting 105.8 lb, was diagnosed with epilepsy (What is epilepsy?), induction of anaesthesia, endotracheal intubation, maintenance of anaesthesia and was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: epilepsy (What is epilepsy?). Sevoflurane dosage: 1.2 - 1.5%. During the same period patient was treated with PHENYTOIN (View Phenytoin Review and Phenytoin Label ), BEPOTASTINE BESILATE (View Bepotastine Besilate Review and Bepotastine Besilate Label ), PROPOFOL (View Propofol Review and Propofol Label ), FENTANYL (View Fentanyl Review and Fentanyl Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), OXYGEN (View Oxygen Review and Oxygen Label ), REMIFENTANIL (0.1 - 0.2 Mcg/kg/min) (View Remifentanil Review and Remifentanil Label ).

6470447-0 | Torsade De Pointes, Ventricular Extrasystoles
Patient was taking Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: torsade de pointes, ventricular extrasystoles on Nov 25, 2009 from JAPAN Additional patient health information: Female patient , 13 years of age, was diagnosed with maintenance of anaesthesia, induction of anaesthesia and. Sevoflurane dosage: . During the same period patient was treated with THIOPENTAL SODIUM (View Thiopental Sodium Review and Thiopental Sodium Label ), VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ), NITROUS OXIDE (View Nitrous Oxide Review and Nitrous Oxide Label ).

6466689-0 | Bundle Branch Block
Adverse event was reported on Nov 25, 2009 by a Female patient taking Sevoflurane (View Usage) (Dosage: ) was diagnosed with maintenance of anaesthesia, induction of anaesthesia and. Location: JAPAN , 17 years of age, Patient had the following side effects: bundle branch block. During the same period patient was treated with REMIFENTANIL (View Remifentanil Review and Remifentanil Label ), PROPOFOL (View Propofol Review and Propofol Label ), VECURONIUM BROMIDE (View Vecuronium Bromide Review and Vecuronium Bromide Label ).

6458136-X | Adrenal Adenoma, Hyperglycaemia, Hypokalaemia, Pulmonary Oedema
on Nov 19, 2009 Female patient from JAPAN , weighting 88.18 lb, was diagnosed with hypertension, hypokalaemia, hyperglycaemia, anaesthesia, hypotonia and was treated with Sevoflurane (View Usage). After Sevoflurane was administered, patient had the following side effects: adrenal adenoma, hyperglycaemia, hypokalaemia, pulmonary oedema. Sevoflurane dosage: 4.0-1.0 Percent. During the same period patient was treated with ALDOMET (View Aldomet Review and Aldomet Label ), SLOW K (View Slow-k Review and Slow-k Label ), INSULIN ASPART (View Insulin Aspart Review and Insulin Aspart Label ), ULTIVA (View Ultiva Review and Ultiva Label ), THIOPENTAL SODIUM (View Thiopental Sodium Review and Thiopental Sodium Label ), MUSCURATE (View Muscurate Review and Muscurate Label ), ANAPEINE (View Anapeine Review and Anapeine Label ). Patient was hospitalized.

6453147-2 | Pulmonary Oedema
on Nov 18, 2009 Female patient from JAPAN , weighting 88.18 lb, was diagnosed with hypertension, hypokalaemia, hyperglycaemia, anaesthesia, hypotonia and was treated with Sevoflurane (View Usage). Patient experienced the following unwanted or unexpected effects: pulmonary oedema. Sevoflurane dosage: 4.0-1.0 Percent. During the same period patient was treated with ALDOMET (View Aldomet Review and Aldomet Label ), SLOW K (View Slow-k Review and Slow-k Label ), INSULIN ASPART (View Insulin Aspart Review and Insulin Aspart Label ), ULTIVA (View Ultiva Review and Ultiva Label ), THIOPENTAL SODIUM (View Thiopental Sodium Review and Thiopental Sodium Label ), MUSCURATE (View Muscurate Review and Muscurate Label ), ANAPEINE (View Anapeine Review and Anapeine Label ). Patient was hospitalized.

6450808-6 | Salivary Gland Enlargement
Patient was taking Sevoflurane (View Usage). Patient had the following side effects: salivary gland enlargement on Nov 18, 2009 from JAPAN Additional patient health information: Female patient , 67 years of age, was diagnosed with maintenance of anaesthesia, induction of anaesthesia and. Sevoflurane dosage: . During the same period patient was treated with PROPOFOL (View Propofol Review and Propofol Label ), REMIFENTANIL (View Remifentanil Review and Remifentanil Label ), ROCURONIUM BROMIDE (View Rocuronium Bromide Review and Rocuronium Bromide Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ).