SIROLIMUS Side Effects

6962450-9 | Hepatitis
on Aug 23, 2010 Male patient from FRANCE , 54 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: hepatitis (What is hepatitis?). Sirolimus dosage: . During the same period patient was treated with MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), EPOETIN BETA (View Epoetin Beta Review and Epoetin Beta Label ), IRBESARTAN (View Irbesartan Review and Irbesartan Label ), HYDROCHLOROTHIAZIDE (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ), SULFAMETHOXAZOLE AND TRIMETHOPRIM (View Sulfamethoxazole And Trimethoprim Review and Sulfamethoxazole And Trimethoprim Label ), ATENOLOL (View Atenolol Review and Atenolol Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ). Patient was hospitalized.

6931089-3 | Chronic Sinusitis, Pneumonia Haemophilus
Patient was taking Sirolimus (View Usage). Patient had the following side effects: chronic sinusitis, pneumonia haemophilus on Aug 10, 2010 from NETHERLANDS Additional patient health information: Male patient , 74 years of age, weighting 178.6 lb, was diagnosed with renal transplant, prophylaxis, nephrogenic anaemia, hypocalcaemia, hypercholesterolaemia, cerebrovascular accident prophylaxis and. Sirolimus dosage: . During the same period patient was treated with NEXIUM (View Nexium Review and Nexium Label ), ARANESP (View Aranesp Review and Aranesp Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), CALCICHEW (View Calcichew Review and Calcichew Label ), ETALPHA (View Etalpha Review and Etalpha Label ), LIPITOR (View Lipitor Review and Lipitor Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), ASCAL (View Ascal Review and Ascal Label ). Patient was hospitalized.

6922763-3 | Dyslipidaemia, Escherichia Sepsis, Renal Impairment, Rhabdomyolysis
Adverse event was reported on Aug 02, 2010 by a Female patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with renal transplant, blood cholesterol increased and. Location: CROATIA (local name: Hrvatska) , 66 years of age, After Sirolimus was administered, patient had the following side effects: dyslipidaemia, escherichia sepsis, renal impairment, rhabdomyolysis. During the same period patient was treated with FLUVASTATIN (View Fluvastatin Review and Fluvastatin Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ). Patient was hospitalized.

6847367-2 | Amenorrhoea
on Jul 07, 2010 Female patient from UNITED ARAB EMIRATES , 23 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: amenorrhoea. Sirolimus dosage: .


6844795-6 | Amenorrhoea
on Jul 07, 2010 Female patient from UNITED ARAB EMIRATES , 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus (View Usage). Patient had the following side effects: amenorrhoea. Sirolimus dosage: .

6844784-1 | Amenorrhoea
Patient was taking Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: amenorrhoea on Jul 07, 2010 from UNITED ARAB EMIRATES Additional patient health information: Female patient , 50 years of age, was diagnosed with prophylaxis against transplant rejection and. Sirolimus dosage: .

6819301-2 | Cough
Adverse event was reported on Jun 25, 2010 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with hypertension, proteinuria and. Location: SOUTH AFRICA , weighting 165.3 lb, Patient experienced the following unwanted or unexpected effects: cough. During the same period patient was treated with AMLOR (View Amlor Review and Amlor Label ), PREDNISONE TAB (View Prednisone Tab Review and Prednisone Tab Label ), CELLCEPT (View Cellcept Review and Cellcept Label ).

6790819-4 | Cough
on Jun 13, 2010 Male patient from SOUTH AFRICA , weighting 165.3 lb, was diagnosed with hypertension, proteinuria and was treated with Sirolimus (View Usage). Patient had the following side effects: cough. Sirolimus dosage: . During the same period patient was treated with AMLOR (View Amlor Review and Amlor Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), CELLCEPT (View Cellcept Review and Cellcept Label ).

6781382-2 | Cerebral Infarction
on Jun 16, 2010 Female patient from AUSTRIA , weighting 172.0 lb, was diagnosed with prophylaxis against transplant rejection, prophylaxis against gastrointestinal ulcer, hyperlipidaemia, anaemia and was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: cerebral infarction. Sirolimus dosage: . During the same period patient was treated with LOSARTAN (View Losartan Review and Losartan Label ), CELLCEPT (View Cellcept Review and Cellcept Label ), PARIET (View Pariet Review and Pariet Label ), SORTIS ^PARKE DAVIS^ (View Sortis ^parke-davis^ Review and Sortis ^parke-davis^ Label ), FERRETAB COMP (View Ferretab Comp Review and Ferretab Comp Label ). Patient was hospitalized.

6756025-4 | Kidney Fibrosis, Kidney Transplant Rejection, Renal Tubular Atrophy
Patient was taking Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: kidney fibrosis, kidney transplant rejection, renal tubular atrophy on May 26, 2010 from BRAZIL Additional patient health information: Male patient , weighting 173.1 lb, was diagnosed with prophylaxis against transplant rejection and. Sirolimus dosage: . During the same period patient was treated with MYCOPHENOLIC ACID (View Mycophenolic Acid Review and Mycophenolic Acid Label ), PREDNISONE (View Prednisone Review and Prednisone Label ).

6735516-6 | Cough
Adverse event was reported on May 10, 2010 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with hypertension, proteinuria and. Location: SOUTH AFRICA , weighting 165.3 lb, Patient had the following side effects: cough. During the same period patient was treated with AMLOR (View Amlor Review and Amlor Label ), PREDNISONE TAB (View Prednisone Tab Review and Prednisone Tab Label ), CELLCEPT (View Cellcept Review and Cellcept Label ).

6722645-6 | Cerebral Infarction
on May 03, 2010 Female patient from AUSTRIA , weighting 172.0 lb, was diagnosed with prophylaxis against transplant rejection, prophylaxis against gastrointestinal ulcer, hyperlipidaemia, anaemia and was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: cerebral infarction. Sirolimus dosage: . During the same period patient was treated with LOSARTAN POTASSIUM (View Losartan Potassium Review and Losartan Potassium Label ), CELLCEPT (View Cellcept Review and Cellcept Label ), PARIET (View Pariet Review and Pariet Label ), SORTIS ^PARKE DAVIS^ (View Sortis ^parke-davis^ Review and Sortis ^parke-davis^ Label ), FERRETAB COMP (View Ferretab Comp Review and Ferretab Comp Label ). Patient was hospitalized.

6701012-5 | Accidental Overdose
on Apr 19, 2010 Female patient from UNITED STATES , weighting 122.1 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: accidental overdose. Sirolimus dosage: . During the same period patient was treated with PREDNISONE (5 Mg ^sid^) (View Prednisone Review and Prednisone Label ), OS CAL + D (View Os-cal + D Review and Os-cal + D Label ), TRAZODONE HCL (View Trazodone Hcl Review and Trazodone Hcl Label ), XANAX (View Xanax Review and Xanax Label ), METOPROLOL TARTRATE (View Metoprolol Tartrate Review and Metoprolol Tartrate Label ), PROGRAF (View Prograf Review and Prograf Label ), MAGNESIUM OXIDE (View Magnesium Oxide Review and Magnesium Oxide Label ). Patient was hospitalized.

6681158-0 | Organising Pneumonia, Pulmonary Alveolar Haemorrhage
Patient was taking Sirolimus (View Usage). Patient had the following side effects: organising pneumonia, pulmonary alveolar haemorrhage on Apr 05, 2010 from PORTUGAL Additional patient health information: Male patient , 71 years of age, . Sirolimus dosage: . During the same period patient was treated with PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ). Patient was hospitalized.

6671628-3 | Cough, Pneumonitis
Adverse event was reported on Apr 06, 2010 by a Female patient taking Sirolimus (View Usage) (Dosage: Po) was diagnosed with renal transplant and. Location: UNITED STATES , 66 years of age, After Sirolimus was administered, patient had the following side effects: cough, pneumonitis.

6670963-2 | Blood Creatinine Increased, Dyspnoea
on Apr 06, 2010 Male patient from UNITED STATES , weighting 251.3 lb, was diagnosed with immunosuppression, polyuria, vitamin supplementation, mineral supplementation, gastrooesophageal reflux disease, hypertension and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: blood creatinine increased, dyspnoea. Sirolimus dosage: . During the same period patient was treated with BUMEX (View Bumex Review and Bumex Label ), ERGOCALCIFEROL (View Ergocalciferol Review and Ergocalciferol Label ), ROCALTROL (View Rocaltrol Review and Rocaltrol Label ), CALCIUM CARBONATE (View Calcium Carbonate Review and Calcium Carbonate Label ), PEPCID (View Pepcid Review and Pepcid Label ), LABETALOL HCL (View Labetalol Hcl Review and Labetalol Hcl Label ), PREDNISONE TAB (View Prednisone Tab Review and Prednisone Tab Label ), CRESTOR (View Crestor Review and Crestor Label ). Patient was hospitalized.

6668266-5 | Low Density Lipoprotein Increased, Pneumonitis
on Apr 05, 2010 Male patient from UNITED STATES , weighting 54.67 lb, was diagnosed with neurofibromatosis (What is neurofibromatosis?) and was treated with Sirolimus (View Usage). Patient had the following side effects: low density lipoprotein increased, pneumonitis. Sirolimus dosage: 1.0 Mg Bid Oral. During the same period patient was treated with TYLENOL FOR FEVER (View Tylenol For Fever Review and Tylenol For Fever Label ).

6646484-X | Blood Creatinine Increased, Dyspnoea
Patient was taking Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: blood creatinine increased, dyspnoea on Mar 19, 2010 from UNITED STATES Additional patient health information: Male patient , weighting 251.3 lb, was diagnosed with immunosuppression, polyuria, vitamin supplementation, mineral supplementation, gastrooesophageal reflux disease, hypertension and. Sirolimus dosage: . During the same period patient was treated with BUMEX (View Bumex Review and Bumex Label ), ERGOCALCIFEROL (View Ergocalciferol Review and Ergocalciferol Label ), ROCALTROL (View Rocaltrol Review and Rocaltrol Label ), CALCIUM CARBONATE (View Calcium Carbonate Review and Calcium Carbonate Label ), PEPCID (View Pepcid Review and Pepcid Label ), LABETALOL HCL (View Labetalol Hcl Review and Labetalol Hcl Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), CRESTOR (View Crestor Review and Crestor Label ). Patient was hospitalized.

6637868-4 | Kidney Fibrosis, Kidney Transplant Rejection, Renal Tubular Atrophy
Adverse event was reported on Mar 12, 2010 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with prophylaxis against transplant rejection and. Location: BRAZIL , weighting 125.7 lb, Patient experienced the following unwanted or unexpected effects: kidney fibrosis, kidney transplant rejection, renal tubular atrophy. During the same period patient was treated with MYFORTIC (View Myfortic Review and Myfortic Label ), PREDNISONE (View Prednisone Review and Prednisone Label ). Patient was hospitalized.

6637696-X | Cataract, Lenticular Opacities, Visual Acuity Reduced
on Feb 26, 2010 Female patient from UNITED STATES , 32 years of age, was diagnosed with uveitis and was treated with Sirolimus (View Usage). Patient had the following side effects: cataract (What is cataract?), lenticular opacities, visual acuity reduced. Sirolimus dosage: 16 Ul Intravitreal. During the same period patient was treated with PREDNISONE (View Prednisone Review and Prednisone Label ), PROTONIX (View Protonix Review and Protonix Label ).

6596360-6 | Hypertension, Low Density Lipoprotein Increased
on Feb 22, 2010 Female patient from UNITED STATES , child 6 years of age, weighting 47.09 lb, was diagnosed with neurofibromatosis (What is neurofibromatosis?) and was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: hypertension, low density lipoprotein increased. Sirolimus dosage: 2.3 Mg Bid; 1.7 Mg Bid. During the same period patient was treated with NEURONTIN (View Neurontin Review and Neurontin Label ).

6594941-7 | Impaired Healing
Patient was taking Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: impaired healing on Feb 18, 2010 from AUSTRALIA Additional patient health information: Male patient , weighting 199.5 lb, was diagnosed with prophylaxis against transplant rejection, proteinuria, diabetes mellitus, hypertension, colitis ulcerative and. Sirolimus dosage: . During the same period patient was treated with LOSARTAN POTASSIUM (View Losartan Potassium Review and Losartan Potassium Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), METFORMIN (View Metformin Review and Metformin Label ), GLICLAZIDE (View Gliclazide Review and Gliclazide Label ), METOPROLOL TARTRATE (View Metoprolol Tartrate Review and Metoprolol Tartrate Label ), SULFASALAZINE (View Sulfasalazine Review and Sulfasalazine Label ). Patient was hospitalized.

6585245-7 | Impaired Healing
Adverse event was reported on Feb 05, 2010 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with prophylaxis against transplant rejection, proteinuria, diabetes mellitus, hypertension, colitis ulcerative and. Location: AUSTRALIA , weighting 199.5 lb, Patient had the following side effects: impaired healing. During the same period patient was treated with LOSARTAN POTASSIUM (View Losartan Potassium Review and Losartan Potassium Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), METFORMIN (View Metformin Review and Metformin Label ), GLICLAZIDE (View Gliclazide Review and Gliclazide Label ), METOPROLOL TARTRATE (View Metoprolol Tartrate Review and Metoprolol Tartrate Label ), SULFASALAZINE (View Sulfasalazine Review and Sulfasalazine Label ). Patient was hospitalized.

6583870-0 | Low Density Lipoprotein Increased
on Feb 13, 2010 Male patient from UNITED STATES , weighting 53.79 lb, was diagnosed with neurofibromatosis (What is neurofibromatosis?) and was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: low density lipoprotein increased. Sirolimus dosage: 2.0 Mg Bid Po. During the same period patient was treated with CHOLESTYRAMINE POWDER (View Cholestyramine Powder Review and Cholestyramine Powder Label ), CIPRO (View Cipro Review and Cipro Label ), BACTRIM PREVACID (View Bactrim Prevacid Review and Bactrim Prevacid Label ).

6583818-9 | Low Density Lipoprotein Increased, Pneumonitis
on Feb 13, 2010 Male patient from UNITED STATES , weighting 54.67 lb, was diagnosed with neurofibromatosis (What is neurofibromatosis?) and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: low density lipoprotein increased, pneumonitis. Sirolimus dosage: 1.0 Mg Bid Po. During the same period patient was treated with TYLENOL 500 (View Tylenol-500 Review and Tylenol-500 Label ).

6571944-X | Pancreatic Carcinoma
Patient was taking Sirolimus (View Usage). Patient had the following side effects: pancreatic carcinoma on Jan 26, 2010 from CANADA Additional patient health information: Male patient , 67 years of age, weighting 200.6 lb, was diagnosed with prophylaxis against transplant rejection, immunosuppression, dyslipidaemia, hypertension, hypercalcaemia, type 2 diabetes mellitus and. Sirolimus dosage: . During the same period patient was treated with MYCOPHENOLATE MOFETIL (2 G Every) (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), PREDNISONE (7.5 Mg Every) (View Prednisone Review and Prednisone Label ), ATORVASTATIN (10 Mg Every) (View Atorvastatin Review and Atorvastatin Label ), AMLODIPINE (10 Mg Every) (View Amlodipine Review and Amlodipine Label ), CANDESARTAN CILEXETIL (8 Mg Every) (View Candesartan Cilexetil Review and Candesartan Cilexetil Label ), CALCIUM CARBONATE/CALCIUM GLUCONATE/CALCIUM LACTATE/ERGOCALCIFEROL (30 Mg Every) (View Calcium Carbonate/calcium Gluconate/calcium Lactate/ergocalciferol Review and Calcium Carbonate/calcium Gluconate/calcium Lactate/ergocalciferol Label ), INSULIN HUMAN (42 Unit Every) (View Insulin Human Review and Insulin Human Label ), ISOPHANE INSULIN (22 Unit Every) (View Isophane Insulin Review and Isophane Insulin Label ). Patient was hospitalized.

6558555-7 | Impaired Healing
Adverse event was reported on Jan 18, 2010 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with prophylaxis against transplant rejection, proteinuria, diabetes mellitus, hypertension, colitis ulcerative and. Location: AUSTRALIA , weighting 199.5 lb, After Sirolimus was administered, patient had the following side effects: impaired healing. During the same period patient was treated with LOSARTAN POTASSIUM (View Losartan Potassium Review and Losartan Potassium Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), METFORMIN (View Metformin Review and Metformin Label ), GLICLAZIDE (View Gliclazide Review and Gliclazide Label ), METOPROLOL (View Metoprolol Review and Metoprolol Label ), SULFASALAZINE (View Sulfasalazine Review and Sulfasalazine Label ). Patient was hospitalized.

6532378-7 | Chest Pain, Dyspnoea Exertional
on Jan 06, 2010 Female patient from UNITED STATES , weighting 211.9 lb, was diagnosed with prophylaxis against transplant rejection, diabetes mellitus, sinus congestion, hypersensitivity, constipation (What is constipation?), mineral supplementation, hypertension, dermatitis allergic and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: chest pain (What is chest pain?), dyspnoea exertional. Sirolimus dosage: . During the same period patient was treated with ACTOS (View Actos Review and Actos Label ), ALLEGRA D 24 HOUR (180 Mg Every 1 Prn) (View Allegra D 24 Hour Review and Allegra D 24 Hour Label ), AMARYL (View Amaryl Review and Amaryl Label ), AMITIZA (24 Mg Every 1 Prn) (View Amitiza Review and Amitiza Label ), CALCIUM WITH VITAMIN D (View Calcium With Vitamin D Review and Calcium With Vitamin D Label ), CARVEDILOL (View Carvedilol Review and Carvedilol Label ), CORTIZONE 10 (1% Twice Daily, As Needed) (View Cortizone 10 Review and Cortizone 10 Label ). Patient was hospitalized.

6518167-8 | Viral Infection
on Dec 23, 2009 Female patient from UNITED STATES , weighting 17.60 lb, was treated with Sirolimus (View Usage). Patient had the following side effects: viral infection (What is viral infection?). Sirolimus dosage: 1 Mg Bid Po. During the same period patient was treated with TYLENOL (CAPLET) (View Tylenol (caplet) Review and Tylenol (caplet) Label ), MOTRIN (View Motrin Review and Motrin Label ). Patient was hospitalized.

6504901-X | Chest Pain, Dyspnoea Exertional
Patient was taking Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: chest pain (What is chest pain?), dyspnoea exertional on Dec 09, 2009 from UNITED STATES Additional patient health information: Female patient , weighting 211.9 lb, was diagnosed with prophylaxis against transplant rejection, diabetes mellitus, sinus congestion, hypersensitivity, constipation (What is constipation?), mineral supplementation, hypertension, dermatitis allergic and. Sirolimus dosage: . During the same period patient was treated with ACTOS (View Actos Review and Actos Label ), ALLEGRA D 24 HOUR (180 Mg Every 1 Prn) (View Allegra D 24 Hour Review and Allegra D 24 Hour Label ), AMARYL (View Amaryl Review and Amaryl Label ), AMITIZA (24 Mg Every 1 Prn) (View Amitiza Review and Amitiza Label ), CALCIUM WITH VITAMIN D (View Calcium With Vitamin D Review and Calcium With Vitamin D Label ), CARVEDILOL (View Carvedilol Review and Carvedilol Label ), CORTIZONE 10 (1% Twice Daily, As Needed) (View Cortizone 10 Review and Cortizone 10 Label ). Patient was hospitalized.

6478512-9 | Venoocclusive Disease
Adverse event was reported on Dec 02, 2009 by a Male patient taking Sirolimus (View Usage) (Dosage: 2.5mg/m2, Max 4mg Daily, Target Level 3-12ng/ml Then Dose Tapered At Six Months) was diagnosed with prophylaxis against graft versus host disease, stem cell transplant, acute lymphocytic leukaemia and. Location: UNITED STATES , child 9 years of age, Patient experienced the following unwanted or unexpected effects: venoocclusive disease. During the same period patient was treated with CYCLOPHOSPHAMIDE (60mg/kg/d (total Dose 120mg/kg)) (View Cyclophosphamide Review and Cyclophosphamide Label ), THIOTEPA (5mg/kg/d (total Dose 10mg/kg)) (View Thiotepa Review and Thiotepa Label ), TACROLIMUS (Starting On Day -2 (starting Dose 0.03mg/kg D) Target Level 5-10 Ng/ml; Then Dose Tapered) (View Tacrolimus Review and Tacrolimus Label ), METHOTREXATE (5mg/m2 On Days +1, +3 And +6 After Transplant) (View Methotrexate Review and Methotrexate Label ).

6478510-5 | Venoocclusive Disease
on Dec 02, 2009 Female patient from UNITED STATES , 20 years of age, was diagnosed with prophylaxis against graft versus host disease, stem cell transplant, acute lymphocytic leukaemia and was treated with Sirolimus (View Usage). Patient had the following side effects: venoocclusive disease. Sirolimus dosage: 2.5mg/m2, Max 4mg Daily, Target Level 3-12ng/ml Then Tapered At 6 Months. During the same period patient was treated with CYCLOPHOSPHAMIDE (60mg/kg/d (total Dose 120mg/kg)) (View Cyclophosphamide Review and Cyclophosphamide Label ), THIOTEPA (5mg/kg/d (total Dose 10mg/kg)) (View Thiotepa Review and Thiotepa Label ), TACROLIMUS (Starting On Day -2 (starting Dose 0.03mg/kg D) Target Level 5-10 Ng/ml; Then Dose Tapered) (View Tacrolimus Review and Tacrolimus Label ), METHOTREXATE (5mg/m2 On Days +1, +3 And +6 After Transplant) (View Methotrexate Review and Methotrexate Label ).

6478509-9 | Venoocclusive Disease
on Dec 02, 2009 Male patient from UNITED STATES , child 6 years of age, was diagnosed with prophylaxis against graft versus host disease, stem cell transplant, acute lymphocytic leukaemia and was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: venoocclusive disease. Sirolimus dosage: 2.5mg/m2, Max 4mg Daily, Target Level 3-12ng/ml Then Dose Tapered At Six Months. During the same period patient was treated with CYCLOPHOSPHAMIDE (60mg/kg/d (total Dose 120 Mg/kg)) (View Cyclophosphamide Review and Cyclophosphamide Label ), THIOTEPA (5mg/kg/d (total Dose 10mg/kg)) (View Thiotepa Review and Thiotepa Label ), TACROLIMUS (2.5mg/m2, Max 4mg Daily, Target Level 3-12ng/ml Then Tapered At 6 Months) (View Tacrolimus Review and Tacrolimus Label ), METHOTREXATE (5mg/m2 On Days +1, +3 And +6 After Transplant) (View Methotrexate Review and Methotrexate Label ).

6467507-7 | Blood Creatinine Increased, Dyspnoea
Patient was taking Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: blood creatinine increased, dyspnoea on Nov 20, 2009 from UNITED STATES Additional patient health information: Male patient , weighting 265.0 lb, was diagnosed with immunosuppression, hypercholesterolaemia, vitamin supplementation, mineral supplementation, gastrooesophageal reflux disease, hypertension and. Sirolimus dosage: . During the same period patient was treated with LIPITOR (View Lipitor Review and Lipitor Label ), ERGOCALCIFEROL (View Ergocalciferol Review and Ergocalciferol Label ), ROCALTROL (View Rocaltrol Review and Rocaltrol Label ), CALCIUM CARBONATE (View Calcium Carbonate Review and Calcium Carbonate Label ), PEPCID (View Pepcid Review and Pepcid Label ), LABETALOL HCL (View Labetalol Hcl Review and Labetalol Hcl Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), CRESTOR (View Crestor Review and Crestor Label ). Patient was hospitalized.

6467279-6 | Kidney Fibrosis, Kidney Transplant Rejection, Renal Tubular Atrophy
Adverse event was reported on Nov 26, 2009 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with prophylaxis against transplant rejection and. Location: BRAZIL , weighting 125.7 lb, Patient had the following side effects: kidney fibrosis, kidney transplant rejection, renal tubular atrophy. During the same period patient was treated with MYFORTIC (View Myfortic Review and Myfortic Label ), PREDNISONE (View Prednisone Review and Prednisone Label ). Patient was hospitalized.

6414791-1 | Blister, Rash, Skin Exfoliation
on Oct 26, 2009 Male patient from UNITED STATES , weighting 275.6 lb, was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: blister, rash (What is rash?), skin exfoliation. Sirolimus dosage: .

6414789-3 | Stomatitis
on Oct 26, 2009 Male patient from UNITED STATES , weighting 130.3 lb, was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: stomatitis. Sirolimus dosage: .

6387118-1 | Prostate Cancer
Patient was taking Sirolimus (View Usage). Patient had the following side effects: prostate cancer (What is prostate cancer?) on Sep 24, 2009 from UNITED STATES Additional patient health information: Male patient , weighting 188.3 lb, was diagnosed with renal transplant and. Sirolimus dosage: .

6387117-X | Kaposi's Sarcoma
Adverse event was reported on Sep 23, 2009 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with prophylaxis against transplant rejection and. Location: ITALY , 74 years of age, After Sirolimus was administered, patient had the following side effects: kaposi's sarcoma (What is kaposi's sarcoma?). During the same period patient was treated with MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ).

6382290-1 | Fatigue, Interstitial Lung Disease, Weight Decreased
on Sep 24, 2009 Male patient from UNITED KINGDOM , 53 years of age, weighting 165.3 lb, was diagnosed with immunosuppression, prophylaxis against gastrointestinal ulcer and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: fatigue, interstitial lung disease, weight decreased. Sirolimus dosage: . During the same period patient was treated with AZATHIOPRINE (View Azathioprine Review and Azathioprine Label ), RANITIDINE (View Ranitidine Review and Ranitidine Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ), PRAVASTATIN (View Pravastatin Review and Pravastatin Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), ARANESP (View Aranesp Review and Aranesp Label ). Patient was hospitalized.

6346465-X | Prostate Cancer
on Sep 04, 2009 Male patient from UNITED STATES , weighting 188.3 lb, was diagnosed with renal transplant and was treated with Sirolimus (View Usage). Patient had the following side effects: prostate cancer (What is prostate cancer?). Sirolimus dosage: .

6343064-0 | Prostate Cancer
Patient was taking Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: prostate cancer (What is prostate cancer?) on Sep 02, 2009 from UNITED STATES Additional patient health information: Male patient , weighting 188.3 lb, was diagnosed with renal transplant and. Sirolimus dosage: .

6343062-7 | Atrioventricular Block, Cellulitis, Interstitial Lung Disease, Necrosis, Skin Ulcer
Adverse event was reported on Sep 03, 2009 by a Male patient taking Sirolimus (View Usage) (Dosage: ) . Location: UNITED KINGDOM , weighting 212.7 lb, Patient experienced the following unwanted or unexpected effects: atrioventricular block, cellulitis (What is cellulitis?), interstitial lung disease, necrosis, skin ulcer. During the same period patient was treated with BECONASE (View Beconase Review and Beconase Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), WARFARIN SODIUM (View Warfarin Sodium Review and Warfarin Sodium Label ), DOXAZOSIN (View Doxazosin Review and Doxazosin Label ), PROBENECID (View Probenecid Review and Probenecid Label ), DILTIAZEM (View Diltiazem Review and Diltiazem Label ). Patient was hospitalized.

6314003-3 | Obstructive Airways Disorder, Oedema Peripheral, Pleural Effusion, Proteinuria
on Aug 14, 2009 Female patient from NETHERLANDS , 47 years of age, was diagnosed with immunosuppression and was treated with Sirolimus (View Usage). Patient had the following side effects: obstructive airways disorder, oedema peripheral, pleural effusion, proteinuria. Sirolimus dosage: Titrated Dose To Maintain Initial Trough Levels Of 10-15 Ug/l. During the same period patient was treated with PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ). Patient was hospitalized.

6310256-6 | Atrioventricular Block, Cellulitis, Interstitial Lung Disease, Necrosis, Skin Ulcer
on Aug 13, 2009 Male patient from UNITED KINGDOM , weighting 212.7 lb, was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: atrioventricular block, cellulitis (What is cellulitis?), interstitial lung disease, necrosis, skin ulcer. Sirolimus dosage: . During the same period patient was treated with BECONASE (View Beconase Review and Beconase Label ), PROBENECID (View Probenecid Review and Probenecid Label ), SOTALOL HYDROCHLORIDE (View Sotalol Hydrochloride Review and Sotalol Hydrochloride Label ), WARFARIN (View Warfarin Review and Warfarin Label ), DOXAZOSIN (View Doxazosin Review and Doxazosin Label ), DILTIAZEM (View Diltiazem Review and Diltiazem Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ). Patient was hospitalized.

6294806-4 | Necrosis, Skin Ulcer
Patient was taking Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: necrosis, skin ulcer on Jul 29, 2009 from UNITED KINGDOM Additional patient health information: Male patient , weighting 212.7 lb, . Sirolimus dosage: . During the same period patient was treated with BECONASE (View Beconase Review and Beconase Label ), PROBENECID (View Probenecid Review and Probenecid Label ), SOTALOL HCL (View Sotalol Hcl Review and Sotalol Hcl Label ), WARFARIN SODIUM (View Warfarin Sodium Review and Warfarin Sodium Label ), DOXAZOSIN MESYLATE (View Doxazosin Mesylate Review and Doxazosin Mesylate Label ), DILTIAZEM (View Diltiazem Review and Diltiazem Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ). Patient was hospitalized.

6254475-6 | Pancreatitis Acute
Adverse event was reported on Jun 25, 2009 by a Male patient taking Sirolimus (View Usage) (Dosage: ) was diagnosed with prophylaxis against transplant rejection, diabetes mellitus and. Location: KOREA, REPUBLIC OF , weighting 147.7 lb, Patient had the following side effects: pancreatitis acute. During the same period patient was treated with AMARYL (View Amaryl Review and Amaryl Label ). Patient was hospitalized.

6250619-0 | Pancreatitis Acute
on Jun 22, 2009 Male patient from CZECH REPUBLIC , 49 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus (View Usage). After Sirolimus was administered, patient had the following side effects: pancreatitis acute. Sirolimus dosage: . During the same period patient was treated with MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), AMPHOTERICIN B (View Amphotericin B Review and Amphotericin B Label ), METOPROLOL SUCCINATE (View Metoprolol Succinate Review and Metoprolol Succinate Label ), AMBROXOL (View Ambroxol Review and Ambroxol Label ), DACLIZUMAB (165 Mg, Single Dose) (View Daclizumab Review and Daclizumab Label ), METHYLPREDNISOLONE (250 Mg Single Dose) (View Methylprednisolone Review and Methylprednisolone Label ). Patient was hospitalized.

6244232-9 | Pneumonia Aspiration
on Jun 16, 2009 Male patient from EGYPT , 51 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus (View Usage). Patient experienced the following unwanted or unexpected effects: pneumonia aspiration. Sirolimus dosage: 3 Mg/day Initial Dose. During the same period patient was treated with MYCOPHENOLATE MOFETIL (Not Provided) (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), CYCLOSPORINE (Not Provided) (View Cyclosporine Review and Cyclosporine Label ). Patient was hospitalized.

6237971-7 | Cytomegalovirus Infection, Hyperlipidaemia, Transplant Rejection
Patient was taking Sirolimus (View Usage). Patient had the following side effects: cytomegalovirus infection (What is cytomegalovirus infection?), hyperlipidaemia, transplant rejection on Jun 10, 2009 from UNITED STATES Additional patient health information: Female patient , 48 years of age, was diagnosed with prophylaxis against transplant rejection and. Sirolimus dosage: . During the same period patient was treated with MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ).