SYMMETREL Side Effects

7023094-6 | Renal Impairment, Tremor
on Sep 17, 2010 Male patient from JAPAN , 62 years of age, was diagnosed with parkinson's disease (What is parkinson's disease?) and was treated with Symmetrel (View Usage). Patient experienced the following unwanted or unexpected effects: renal impairment, tremor. Symmetrel dosage: 50 Mg, Tid. During the same period patient was treated with COMTAN (View Comtan Review and Comtan Label ), LEVODOPA (View Levodopa Review and Levodopa Label ). Patient was hospitalized.

6572802-7 | Bundle Branch Block Left, Cardiomyopathy, Catheterisation Cardiac, Chest Discomfort, Decreased Appetite, Depressed Level Of Consciousness, Dry Skin, Muscle Rigidity, Myocardial Ischaemia
Patient was taking Symmetrel (View Usage). Patient had the following side effects: bundle branch block left, cardiomyopathy (What is cardiomyopathy?), catheterisation cardiac, chest discomfort, decreased appetite, depressed level of consciousness, dry skin, muscle rigidity, myocardial ischaemia on Aug 28, 2009 from JAPAN Additional patient health information: Female patient , 62 years of age, was diagnosed with parkinson's disease (What is parkinson's disease?) and. Symmetrel dosage: 300 Mg. During the same period patient was treated with PARLODEL (View Parlodel Review and Parlodel Label ), PRAMIPEXOLE DIHYDROCHLORIDE (1.5 Mg) (View Pramipexole Dihydrochloride Review and Pramipexole Dihydrochloride Label ), CARBIDOPA AND LEVODOPA (500 Mg) (View Carbidopa And Levodopa Review and Carbidopa And Levodopa Label ). Patient was hospitalized.

6343351-6 | Bundle Branch Block Left, Cardiomyopathy, Catheterisation Cardiac, Chest Discomfort, Decreased Appetite, Depressed Level Of Consciousness, Dry Skin, Muscle Rigidity, Myocardial Ischaemia
Adverse event was reported on Aug 28, 2009 by a Female patient taking Symmetrel (View Usage) (Dosage: 300 Mg) was diagnosed with parkinson's disease (What is parkinson's disease?) and. Location: JAPAN , 62 years of age, After Symmetrel was administered, patient had the following side effects: bundle branch block left, cardiomyopathy (What is cardiomyopathy?), catheterisation cardiac, chest discomfort, decreased appetite, depressed level of consciousness, dry skin, muscle rigidity, myocardial ischaemia. During the same period patient was treated with PARLODEL (View Parlodel Review and Parlodel Label ), PRAMIPEXOLE DIHYDROCHLORIDE (1.5 Mg) (View Pramipexole Dihydrochloride Review and Pramipexole Dihydrochloride Label ), CARBIDOPA AND LEVODOPA (500 Mg) (View Carbidopa And Levodopa Review and Carbidopa And Levodopa Label ). Patient was hospitalized.

6330798-7 | Cardiomyopathy, Neuroleptic Malignant Syndrome
on Aug 19, 2009 Female patient from JAPAN , 62 years of age, was diagnosed with parkinson's disease (What is parkinson's disease?) and was treated with Symmetrel (View Usage). Patient experienced the following unwanted or unexpected effects: cardiomyopathy (What is cardiomyopathy?), neuroleptic malignant syndrome. Symmetrel dosage: 300mg. During the same period patient was treated with PARLODEL (View Parlodel Review and Parlodel Label ), PRAMIPEXOLE DIHYDROCHLORIDE (1.5mg) (View Pramipexole Dihydrochloride Review and Pramipexole Dihydrochloride Label ), CARBIDOPA AND LEVODOPA (500mg) (View Carbidopa And Levodopa Review and Carbidopa And Levodopa Label ). Patient was hospitalized.


6188991-2 | Disorientation, Hallucination
on May 12, 2009 Female patient from UNITED STATES , 85 years of age, weighting 105.0 lb, was diagnosed with parkinson's disease (What is parkinson's disease?) and was treated with Symmetrel (View Usage). Patient had the following side effects: disorientation, hallucination. Symmetrel dosage: 200mg B I D Q 12 H Po. During the same period patient was treated with INSULIN (View Insulin Review and Insulin Label ). Patient was hospitalized.

6029940-7 | Accidental Overdose, Agitation, Insomnia, Loss Of Consciousness, Nervousness, Tremor
Patient was taking Symmetrel (View Usage). After Symmetrel was administered, patient had the following side effects: accidental overdose, agitation, insomnia, loss of consciousness, nervousness, tremor on Aug 28, 2008 from ITALY Additional patient health information: Male patient , child 9 years of age, was diagnosed with neuromyopathy, influenza immunisation, autism (What is autism?) and. Symmetrel dosage: Total Daily Dose-250mg/d(125 Mg Po Q12h); Formulation=syrup. During the same period patient was treated with TRAZODONE HCL (View Trazodone Hcl Review and Trazodone Hcl Label ).

5892676-7 | Hyponatraemia, Pyrexia
Adverse event was reported on Sep 16, 2008 by a Male patient taking Symmetrel (View Usage) (Dosage: ) was diagnosed with parkinson's disease (What is parkinson's disease?) and. Location: JAPAN , 60 years of age, Patient experienced the following unwanted or unexpected effects: hyponatraemia, pyrexia. During the same period patient was treated with COMTAN (View Comtan Review and Comtan Label ), CABASER (View Cabaser Review and Cabaser Label ), PRAMIPEXOLE DIHYDROCHLORIDE (View Pramipexole Dihydrochloride Review and Pramipexole Dihydrochloride Label ), PERMAX (View Permax Review and Permax Label ), CARBIDOPA + LEVODOPA (View Carbidopa + Levodopa Review and Carbidopa + Levodopa Label ), FP (View Fp Review and Fp Label ). Patient was hospitalized.

5881534-X | Accidental Overdose, Agitation, Dyskinesia, Loss Of Consciousness, Nervousness, Sleep Disorder
on Aug 28, 2008 Male patient from UNITED STATES , child 9 years of age, was diagnosed with influenza immunisation, neuromyopathy, autism (What is autism?) and was treated with Symmetrel (View Usage). Patient had the following side effects: accidental overdose, agitation, dyskinesia, loss of consciousness, nervousness, sleep disorder (What is sleep disorder?). Symmetrel dosage: 100 Mg, Bid, Per Oral. During the same period patient was treated with TRAZODONE HCL (View Trazodone Hcl Review and Trazodone Hcl Label ).

5718157-9 | Blood Cholesterol Increased, Blood Triglycerides Increased, Cholangitis, Cholecystitis, Cholestasis, Gastroenteritis Staphylococcal, Jaundice, Post Procedural Complication, Post Procedural Infection
on Apr 21, 2008 Female patient from , weighting 121.3 lb, was diagnosed with hypertension, cholangitis, arterial thrombosis and was treated with Symmetrel (View Usage). After Symmetrel was administered, patient had the following side effects: blood cholesterol increased, blood triglycerides increased, cholangitis, cholecystitis, cholestasis, gastroenteritis staphylococcal, jaundice (What is jaundice?), post procedural complication, post procedural infection. Symmetrel dosage: 150 Mg. During the same period patient was treated with PREDNISOLONE (5 Mg) (View Prednisolone Review and Prednisolone Label ), TAGAMET (400 Mg) (View Tagamet Review and Tagamet Label ), SEPAMIT (20 Mg) (View Sepamit Review and Sepamit Label ), BUFFERIN (81 Mg) (View Bufferin Review and Bufferin Label ), SULPERAZON (2 G) (View Sulperazon Review and Sulperazon Label ), CLOPIDOGREL (50 Mg) (View Clopidogrel Review and Clopidogrel Label ).

5676455-1 | Blood Cholesterol Increased, Blood Triglycerides Increased, Gastroenteritis Staphylococcal, Jaundice, Rash, Respiratory Failure
Patient was taking Symmetrel (View Usage). Patient experienced the following unwanted or unexpected effects: blood cholesterol increased, blood triglycerides increased, gastroenteritis staphylococcal, jaundice (What is jaundice?), rash (What is rash?), respiratory failure on Mar 14, 2008 from Additional patient health information: Female patient , weighting 121.3 lb, was diagnosed with hypertension, cholangitis, arterial thrombosis and. Symmetrel dosage: 150 Mg. During the same period patient was treated with PREDNISOLONE (5 Mg) (View Prednisolone Review and Prednisolone Label ), TAGAMET (400 Mg) (View Tagamet Review and Tagamet Label ), SEPAMIT (20 Mg) (View Sepamit Review and Sepamit Label ), BUFFERIN (81 Mg) (View Bufferin Review and Bufferin Label ), SULPERAZON (2 G) (View Sulperazon Review and Sulperazon Label ), CLOPIDOGREL (50 Mg) (View Clopidogrel Review and Clopidogrel Label ).

5533583-9 | Jaundice
Adverse event was reported on Nov 29, 2007 by a Female patient taking Symmetrel (View Usage) (Dosage: 150 Mg) was diagnosed with hypertension, arterial thrombosis and. Location: , weighting 121.3 lb, Patient had the following side effects: jaundice (What is jaundice?). During the same period patient was treated with PREDNISOLONE (5 Mg) (View Prednisolone Review and Prednisolone Label ), TAGAMET (400 Mg) (View Tagamet Review and Tagamet Label ), SEPAMIT (20 Mg) (View Sepamit Review and Sepamit Label ), BUFFERIN (81 Mg) (View Bufferin Review and Bufferin Label ), CLOPIDOGREL (50 Mg) (View Clopidogrel Review and Clopidogrel Label ).

5481200-9 | Decreased Appetite, Hallucination, Visual, Posture Abnormal, Stomach Discomfort, Torticollis
on Oct 01, 2007 Female patient from JAPAN , 77 years of age, was diagnosed with parkinson's disease (What is parkinson's disease?), constipation (What is constipation?), depression (What is depression?) and was treated with Symmetrel (View Usage). After Symmetrel was administered, patient had the following side effects: decreased appetite, hallucination, visual, posture abnormal, stomach discomfort, torticollis. Symmetrel dosage: 1 Tablet/day. During the same period patient was treated with TRIHEXYPHENIDYL HYDROCHLORIDE (1 Tablet/day) (View Trihexyphenidyl Hydrochloride Review and Trihexyphenidyl Hydrochloride Label ), CABERGOLINE (1 Tablet/day) (View Cabergoline Review and Cabergoline Label ), ALOSENN (0.5 G, Unk) (View Alosenn Review and Alosenn Label ), DEPAS (1 G, Unk) (View Depas Review and Depas Label ), PARLODEL (3 Df, Unk) (View Parlodel Review and Parlodel Label ).

5245209-2 | Autonomic Nervous System Imbalance, Blood Cholesterol Increased, Blood Pressure Decreased, Cardiomegaly, Cerebellar Atrophy, Constipation, Contusion, Dysstasia
on Feb 13, 2007 Female patient from JAPAN , 67 years of age, weighting 112.4 lb, was diagnosed with parkinsonism and was treated with Symmetrel (View Usage). Patient experienced the following unwanted or unexpected effects: autonomic nervous system imbalance, blood cholesterol increased, blood pressure decreased, cardiomegaly, cerebellar atrophy, constipation (What is constipation?), contusion, dysstasia. Symmetrel dosage: 50 Mg, Bid. During the same period patient was treated with TRIHEXYPHENIDYL HYDROCHLORIDE (2 Mg, Qd) (View Trihexyphenidyl Hydrochloride Review and Trihexyphenidyl Hydrochloride Label ), LEVODOPA W/BENSERAZIDE/ (200 Mg/day) (View Levodopa W/benserazide/ Review and Levodopa W/benserazide/ Label ), PARLODEL (2.5 Mg, Qd) (View Parlodel Review and Parlodel Label ), TALIPEXOLE (2.0 Mg/day) (View Talipexole Review and Talipexole Label ), CARBIDOPA (View Carbidopa Review and Carbidopa Label ). Patient was hospitalized.

5244069-3 | Apnoea, Autonomic Nervous System Imbalance, Blood Creatine Phosphokinase Increased, Blood Culture Positive, Bradycardia, Constipation, Depressed Level Of Consciousness, Hyperkinesia, Hyperthermia
Patient was taking Symmetrel (View Usage). Patient had the following side effects: apnoea, autonomic nervous system imbalance, blood creatine phosphokinase increased, blood culture positive, bradycardia, constipation (What is constipation?), depressed level of consciousness, hyperkinesia, hyperthermia on Feb 19, 2007 from NETHERLANDS Additional patient health information: Male patient , 78 years of age, weighting 154.3 lb, was diagnosed with parkinson's disease (What is parkinson's disease?) and. Symmetrel dosage: 100 Mg, Qd. During the same period patient was treated with OXAZEPAMUM (10 Mg, Bid) (View Oxazepamum Review and Oxazepamum Label ), PANTOZOL (40 Mg) (View Pantozol Review and Pantozol Label ), MAALOX PLUS /NET/ (1 Df, Bid) (View Maalox Plus /net/ Review and Maalox Plus /net/ Label ), SELEGILINE HYDROCHLORIDE (5 Mg, Bid) (View Selegiline Hydrochloride Review and Selegiline Hydrochloride Label ), FLUDROCORTISONE (View Fludrocortisone Review and Fludrocortisone Label ), ASCAL (100 Mg, Qd) (View Ascal Review and Ascal Label ), PERMAX (5 Mg/day) (View Permax Review and Permax Label ), COMTAN (200 Mg, 6qd) (View Comtan Review and Comtan Label ).

5236937-3 | Autonomic Nervous System Imbalance, Cerebellar Atrophy, Cerebral Atrophy, Constipation, Dysstasia, Fall, Head Injury, Micturition Disorder
Adverse event was reported on Jan 31, 2007 by a Female patient taking Symmetrel (View Usage) (Dosage: 50 Mg, Bid) was diagnosed with parkinsonism and. Location: JAPAN , 67 years of age, weighting 112.4 lb, After Symmetrel was administered, patient had the following side effects: autonomic nervous system imbalance, cerebellar atrophy, cerebral atrophy, constipation (What is constipation?), dysstasia, fall (What is fall?), head injury, micturition disorder. During the same period patient was treated with TRIHEXYPHENIDYL HYDROCHLORIDE (2 Mg, Qd) (View Trihexyphenidyl Hydrochloride Review and Trihexyphenidyl Hydrochloride Label ), LEVODOPA W/BENSERAZIDE/ (View Levodopa W/benserazide/ Review and Levodopa W/benserazide/ Label ), PARLODEL (2.5 Mg, Qd) (View Parlodel Review and Parlodel Label ), TALIPEXOLE (View Talipexole Review and Talipexole Label ), CARBIDOPA (View Carbidopa Review and Carbidopa Label ), NEODOPASOL (100 Mg, Bid) (View Neodopasol Review and Neodopasol Label ). Patient was hospitalized.

5234297-5 | Apnoea, Bradycardia, Hyperkinesia, Hyperthermia
on Feb 05, 2007 Male patient from NETHERLANDS , 78 years of age, weighting 154.3 lb, was diagnosed with parkinson's disease (What is parkinson's disease?) and was treated with Symmetrel (View Usage). Patient experienced the following unwanted or unexpected effects: apnoea, bradycardia, hyperkinesia, hyperthermia. Symmetrel dosage: 100 Mg, Qd. During the same period patient was treated with OXAZEPAMUM (10 Mg, Bid) (View Oxazepamum Review and Oxazepamum Label ), PANTOZOL (40 Mg) (View Pantozol Review and Pantozol Label ), MAALOX PLUS /NET/ (1 Df, Bid) (View Maalox Plus /net/ Review and Maalox Plus /net/ Label ), SELEGILINE HYDROCHLORIDE (5 Mg, Bid) (View Selegiline Hydrochloride Review and Selegiline Hydrochloride Label ), FLUDROCORTISONE (View Fludrocortisone Review and Fludrocortisone Label ), ASCAL (100 Mg, Qd) (View Ascal Review and Ascal Label ), PERMAX (5 Mg/day) (View Permax Review and Permax Label ), COMTAN (200 Mg, 6qd) (View Comtan Review and Comtan Label ).

5200205-6 | Asthenia, Fall, Muscular Weakness, Urinary Incontinence
on Dec 18, 2006 Male patient from NETHERLANDS , 80 years of age, was diagnosed with parkinson's disease (What is parkinson's disease?) and was treated with Symmetrel (View Usage). Patient had the following side effects: asthenia, fall (What is fall?), muscular weakness, urinary incontinence (What is urinary incontinence?). Symmetrel dosage: 100 Mg, Bid. During the same period patient was treated with METOPROLOL SUCCINATE (100 Mg, Qd) (View Metoprolol Succinate Review and Metoprolol Succinate Label ), FUROSEMIDE (20 Mg, Qd) (View Furosemide Review and Furosemide Label ), ASCAL CARDIO (100 Mg, Qd) (View Ascal Cardio Review and Ascal Cardio Label ).

5194854-1 | Prescribed Overdose
Patient was taking Symmetrel (View Usage). After Symmetrel was administered, patient had the following side effects: prescribed overdose on Dec 15, 2006 from UNITED STATES Additional patient health information: Male patient , child 9 years of age, was diagnosed with autism (What is autism?) and. Symmetrel dosage: 125 Mg Q12h Po.

5122575-X | Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Gamma-glutamyltransferase Increased, Hepatic Function Abnormal, Liver Disorder
Adverse event was reported on May 18, 2006 by a Male patient taking Symmetrel (View Usage) (Dosage: 150 Mg/d) was diagnosed with cerebral infarction, gastritis, hypertension, diabetes mellitus and. Location: JAPAN , 68 years of age, weighting 127.9 lb, Patient experienced the following unwanted or unexpected effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood glucose increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, liver disorder. During the same period patient was treated with COAX (3 Df/d) (View Coax Review and Coax Label ), FAMOTIDINE (20 Df/d) (View Famotidine Review and Famotidine Label ), NORVASC (5 Mg/d) (View Norvasc Review and Norvasc Label ), DIOVAN (80 Mg/d) (View Diovan Review and Diovan Label ), BASSAMIN 81 MG (81 Mg/d) (View Bassamin 81 Mg Review and Bassamin 81 Mg Label ), BASEN (0.6 Df/d) (View Basen Review and Basen Label ), NOVOLIN N (View Novolin N Review and Novolin N Label ). Patient was hospitalized.

5107235-3 | Overdose
on Sep 01, 2006 Male patient from UNITED STATES , child 9 years of age, was diagnosed with autism (What is autism?) and was treated with Symmetrel (View Usage). Patient had the following side effects: overdose. Symmetrel dosage: 125 Mg Q12h Po.

5093199-8 | Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Gamma-glutamyltransferase Increased, Hepatic Function Abnormal, Liver Disorder
on May 18, 2006 Male patient from JAPAN , 68 years of age, was diagnosed with cerebral infarction, gastritis, hypertension, diabetes mellitus and was treated with Symmetrel (View Usage). After Symmetrel was administered, patient had the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood glucose increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, liver disorder. Symmetrel dosage: 150 Mg/d. During the same period patient was treated with COAX (3 Df/d) (View Coax Review and Coax Label ), FAMOTIDINE (20 Df/d) (View Famotidine Review and Famotidine Label ), NORVASC (5 Mg/d) (View Norvasc Review and Norvasc Label ), DIOVAN (80 Mg/d) (View Diovan Review and Diovan Label ), BASSAMIN 81 MG (81 Mg/d) (View Bassamin 81 Mg Review and Bassamin 81 Mg Label ), BASEN (0.6 Df/d) (View Basen Review and Basen Label ), NOVOLIN N (View Novolin N Review and Novolin N Label ). Patient was hospitalized.

4890868-7 | Confusional State, Renal Failure
Patient was taking Symmetrel (View Usage). Patient experienced the following unwanted or unexpected effects: confusional state, renal failure on Dec 12, 2005 from JAPAN Additional patient health information: Male patient , 53 years of age, was diagnosed with cerebral infarction and. Symmetrel dosage: 50 Mg/day. During the same period patient was treated with DIOVAN (80 Mg/d) (View Diovan Review and Diovan Label ), LASIX (40 Mg/d) (View Lasix Review and Lasix Label ), CARDENALIN (2 Mg/d) (View Cardenalin Review and Cardenalin Label ), LUVOX (50 Mg/d) (View Luvox Review and Luvox Label ), SELBEX (150 Mg/d) (View Selbex Review and Selbex Label ), TAGAMET (400 Mg/d) (View Tagamet Review and Tagamet Label ), BUP 4 (20 Mg/d) (View Bup-4 Review and Bup-4 Label ). Patient was hospitalized.

4619885-9 | Anaemia, Blood Creatinine Decreased, Blood Urea Decreased, Hyponatraemia, Treatment Noncompliance
Adverse event was reported on Feb 04, 2005 by a Male patient taking Symmetrel (View Usage) (Dosage: Daily Dose: 50 Milligram(s)) was diagnosed with ill-defined disorder, depression (What is depression?), hypothyroidism and. Location: , weighting 101.4 lb, Patient had the following side effects: anaemia, blood creatinine decreased, blood urea decreased, hyponatraemia, treatment noncompliance. During the same period patient was treated with DEPROMEL 25 (Daily Dose: 25 Milligram(s)) (View Depromel 25 Review and Depromel 25 Label ), DOGMATYL (Daily Dose: 1 Dosage Form) (View Dogmatyl Review and Dogmatyl Label ), LULLAN (Daily Dose: 12 Milligram(s)) (View Lullan Review and Lullan Label ), THYRADIN (Daily Dose: 125 Microgram(s)) (View Thyradin Review and Thyradin Label ).

4596042-6 | Thinking Abnormal
on Feb 24, 2005 Female patient from , weighting 146.0 lb, was diagnosed with parkinsonism, hypertension and was treated with Symmetrel (View Usage). After Symmetrel was administered, patient had the following side effects: thinking abnormal. Symmetrel dosage: 1 Daily. During the same period patient was treated with MAXZIDE 25 (1 Daily) (View Maxzide-25 Review and Maxzide-25 Label ).