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Tazocin Side Effects

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Common Tazocin Side Effects


The most commonly reported Tazocin side effects (click to view or check a box to report):

Alanine Aminotransferase Increased (24)
Pyrexia (21)
White Blood Cell Count Decreased (18)
Aspartate Aminotransferase Increased (18)
Dyspnoea (15)
Chills (13)
Condition Aggravated (12)
Diarrhoea (12)
Liver Disorder (12)
Rash (11)
Hepatic Function Abnormal (11)
Interstitial Lung Disease (11)
Thrombocytopenia (11)
Septic Shock (10)
Malaise (10)
Blood Lactate Dehydrogenase Increased (10)
Blood Alkaline Phosphatase Increased (10)
Paraesthesia (9)
Nausea (8)
Hypotension (8)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Tazocin Side Effects Reported to FDA



Tazocin Side Effect Report#9496775
Flushing, Chest Discomfort, Respiratory Distress
This is a report of a 86-year-old female patient (weight: NA) from CN, suffering from the following health symptoms/conditions: pneumonia, who was treated with Tazocin (dosage: 4.5 G, 3x/day, start time:
Aug 11, 2012), combined with: NA. and developed a serious reaction and side effect(s): Flushing, Chest Discomfort, Respiratory Distress after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Tazocin treatment in female patients, resulting in Flushing side effect.
Tazocin Side Effect Report#9496768
Bone Marrow Failure, Pyrexia, Chills
This report suggests a potential Tazocin Bone Marrow Failure side effect(s) that can have serious consequences. A 62-year-old male patient (weight: NA) from CN was diagnosed with the following symptoms/conditions: lung abscess and used Tazocin (dosage: 4.5 G, 3x/day) starting
May 03, 2012. After starting Tazocin the patient began experiencing various side effects, including: Bone Marrow Failure, Pyrexia, ChillsAdditional drugs used concurrently: NA. Although Tazocin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Bone Marrow Failure, may still occur.
Tazocin Side Effect Report#9461969
Pyrexia, Condition Aggravated
This Pyrexia problem was reported by a physician from GB. A 9-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: cystic fibrosis. On
Jan 09, 2013 this consumer started treatment with Tazocin (dosage: NA). The following drugs were being taken at the same time:
  • Creon
  • Vitamin A And D
  • Tobi
  • Colomycin
  • Flucloxacillin
  • Azithromycin
  • Ciprofloxacin
  • Augmentin Duo Forte
When using Tazocin, the patient experienced the following unwanted symptoms/side effects: Pyrexia, Condition AggravatedThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pyrexia, may become evident only after a product is in use by the general population.
Tazocin Side Effect Report#9455843
Angioedema, Pulmonary Oedema, Tubulointerstitial Nephritis, Eosinophilia
This Angioedema side effect was reported by a health professional from AU. A 21-year-old male patient (weight:NA) experienced the following symptoms/conditions: sepsis,staphylococcal sepsis.The patient was prescribed Tazocin Ef (drug dosage: 13.5 G, Daily), which was initiated on
May 13, 2000. Concurrently used drugs:
  • Vancomycin Hydrochloride (2 G, 1x/day)
  • Flucloxacillin Sodium (8 G, Daily)
  • Cefazolin
  • Teicoplanin
  • Linezolid
.After starting to take Tazocin Ef the consumer reported adverse symptoms, such as: Angioedema, Pulmonary Oedema, Tubulointerstitial Nephritis, EosinophiliaThese side effects may potentially be related to Tazocin Ef. The patient was hospitalized.
Tazocin Side Effect Report#9455689
Tubulointerstitial Nephritis, Eosinophilia
This is a report of a 41-year-old patient (weight: NA) from AU, suffering from the following health symptoms/conditions: NA, who was treated with Tazocin Ef (dosage: 18 G Daily, start time:
Jun 11, 2012), combined with:
  • Vancomycin Hydrochloride (Unk)
  • Flucloxacillin Sodium (8 G Daily)
  • Naproxen (750 Mg Daily)
and developed a serious reaction and side effect(s): Tubulointerstitial Nephritis, Eosinophilia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Tazocin Ef treatment in patients, resulting in Tubulointerstitial Nephritis side effect.
Tazocin Side Effect Report#9455580
Nephropathy Toxic, Red Man Syndrome
This report suggests a potential Tazocin Ef Nephropathy Toxic side effect(s) that can have serious consequences. A 27-year-old male patient (weight: NA) from AU was diagnosed with the following symptoms/conditions: NA and used Tazocin Ef (dosage: 13.5 G, 1x/day) starting
Jan 24, 2011. After starting Tazocin Ef the patient began experiencing various side effects, including: Nephropathy Toxic, Red Man SyndromeAdditional drugs used concurrently:
  • Vancomycin Hydrochloride (1 Df, 1x/day)
  • Aciclovir
  • Loratadine
  • Pantoprazole
  • Paracetamol
The patient was hospitalized. Although Tazocin Ef demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nephropathy Toxic, may still occur.
Tazocin Side Effect Report#9454375
Mental Disorder, Pneumonia Streptococcal, Malaise, Leukopenia, Neutropenia
This Mental Disorder problem was reported by a physician from GB. A 50-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: pneumonia streptococcal,schizophrenia. On
May 06, 2010 this consumer started treatment with Tazocin (dosage: Unk). The following drugs were being taken at the same time:
  • Clozaril (Unk)
  • Clozaril (450 Mg, Daily)
  • Clozaril (Unk)
When using Tazocin, the patient experienced the following unwanted symptoms/side effects: Mental Disorder, Pneumonia Streptococcal, Malaise, Leukopenia, NeutropeniaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Mental Disorder, may become evident only after a product is in use by the general population.
Tazocin Side Effect Report#9452889
Renal Failure Acute, Ischaemic Hepatitis
This Renal Failure Acute side effect was reported by a pharmacist from AU. A 64-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Tazocin Ef (drug dosage: Unk), which was initiated on
Jun 15, 2009. Concurrently used drugs:
  • Vancomycin (1 G, 2 Times)
.After starting to take Tazocin Ef the consumer reported adverse symptoms, such as: Renal Failure Acute, Ischaemic HepatitisThese side effects may potentially be related to Tazocin Ef.
Tazocin Side Effect Report#9434774
Hepatitis Cholestatic, Liver Function Test Abnormal, Nausea, Vomiting, Jaundice, Encephalopathy, Cholecystitis
This is a report of a 25-year-old male patient (weight: NA) from GB, suffering from the following health symptoms/conditions: infection, who was treated with Tazocin (dosage: 4.5 G, 3x/day, start time:
Apr 29, 2013), combined with: NA. and developed a serious reaction and side effect(s): Hepatitis Cholestatic, Liver Function Test Abnormal, Nausea, Vomiting, Jaundice, Encephalopathy, Cholecystitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Tazocin treatment in male patients, resulting in Hepatitis Cholestatic side effect. The patient was hospitalized.
Tazocin Side Effect Report#9434767
Clostridium Test Positive, Diarrhoea, Nausea, Malaise
This report suggests a potential Tazocin Clostridium Test Positive side effect(s) that can have serious consequences. A 35-year-old patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: pyrexia and used Tazocin (dosage: 4g/500mg, Unk) starting
Aug 24, 2011. After starting Tazocin the patient began experiencing various side effects, including: Clostridium Test Positive, Diarrhoea, Nausea, MalaiseAdditional drugs used concurrently: NA.The patient was hospitalized. Although Tazocin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Clostridium Test Positive, may still occur.
Tazocin Side Effect Report#9425019
Bronchostenosis, Oxygen Saturation Decreased, Urticaria
This Bronchostenosis problem was reported by a physician from IT. A 58-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: pneumonitis. On
Jul 02, 2013 this consumer started treatment with Tazocin (dosage: 4.5 Mg, Total). The following drugs were being taken at the same time:
  • Paracetamol
When using Tazocin, the patient experienced the following unwanted symptoms/side effects: Bronchostenosis, Oxygen Saturation Decreased, UrticariaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Bronchostenosis, may become evident only after a product is in use by the general population.
Tazocin Side Effect Report#9416709
Pneumonia Klebsiella
This Pneumonia Klebsiella side effect was reported by a pharmacist from GB. A 49-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Tazocin (drug dosage: Unk), which was initiated on NS. Concurrently used drugs: NA..After starting to take Tazocin the consumer reported adverse symptoms, such as: Pneumonia KlebsiellaThese side effects may potentially be related to Tazocin.
Tazocin Side Effect Report#9408703
Clostridium Difficile Infection, Pyrexia, C-reactive Protein Increased, White Blood Cell Count Increased, Diarrhoea, Abnormal Faeces, Faeces Discoloured, Lung Consolidation, Pseudomonas Infection
This is a report of a 77-year-old patient (weight: NA) from GB, suffering from the following health symptoms/conditions: pneumonia aspiration, who was treated with Tazocin (dosage: Unk, start time:
Apr 22, 2011), combined with:
  • Co-amoxiclav (1.2g Stat 1000mg/200mg Powder For Solution For Injection Vials)
  • Clarithromycin (500 Mg, Single)
  • Clarithromycin (500 Mg, 2x/day)
  • Levofloxacin (500 Mg, Single)
  • Piperacillin/tazobactam (4.5 G, 3x/day)
  • Piperacillin/tazobactam (4.5 G, 3x/day)
  • Ciprofloxacin (500 Mg, 2x/day)
  • Amoxicillin (500 Mg, 3x/day)
and developed a serious reaction and side effect(s): Clostridium Difficile Infection, Pyrexia, C-reactive Protein Increased, White Blood Cell Count Increased, Diarrhoea, Abnormal Faeces, Faeces Discoloured, Lung Consolidation, Pseudomonas Infection after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Tazocin treatment in patients, resulting in Clostridium Difficile Infection side effect. The patient was hospitalized.
Tazocin Side Effect Report#9374616
Abdominal Pain, Diverticulitis
This report suggests a potential Tazocin Abdominal Pain side effect(s) that can have serious consequences. A 34-year-old female patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: NA and used Tazocin (dosage: 1 Df, Daily) starting
May 23, 2013. After starting Tazocin the patient began experiencing various side effects, including: Abdominal Pain, DiverticulitisAdditional drugs used concurrently: NA.The patient was hospitalized. Although Tazocin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Abdominal Pain, may still occur.
Tazocin Side Effect Report#9371922
Toxic Epidermal Necrolysis, Rhabdomyolysis, Septic Shock, Multi-organ Failure, Acute Respiratory Distress Syndrome
This Toxic Epidermal Necrolysis problem was reported by a health professional from JP. A 77-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: pneumonia aspiration. On
Sep 06, 2006 this consumer started treatment with Tazocin (dosage: 10.0 G, Daily). The following drugs were being taken at the same time: NA. When using Tazocin, the patient experienced the following unwanted symptoms/side effects: Toxic Epidermal Necrolysis, Rhabdomyolysis, Septic Shock, Multi-organ Failure, Acute Respiratory Distress SyndromeAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Toxic Epidermal Necrolysis, may become evident only after a product is in use by the general population.
Tazocin Side Effect Report#9305348
Haematochezia
This Haematochezia side effect was reported by a physician from IT. A 30-year-old female patient (weight:NA) experienced the following symptoms/conditions: crohn^s disease.The patient was prescribed Tazocin (drug dosage: 8 G, 1x/day), which was initiated on
Apr 25, 2012. Concurrently used drugs:
  • Urbason Solubile
  • Asacol
  • Flagyl
  • Esopral
.After starting to take Tazocin the consumer reported adverse symptoms, such as: HaematocheziaThese side effects may potentially be related to Tazocin. The patient was hospitalized.
Tazocin Side Effect Report#9285754
Acute Hepatic Failure, Transaminases Increased
This is a report of a 84-year-old female patient (weight: NA) from IT, suffering from the following health symptoms/conditions: bronchopneumonia, who was treated with Tazocin (dosage: 13.5 G Daily, start time:
Mar 08, 2013), combined with:
  • Lasix
  • K-flebo
  • Coumadin
  • Deponit
  • Dilatrend
and developed a serious reaction and side effect(s): Acute Hepatic Failure, Transaminases Increased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Tazocin treatment in female patients, resulting in Acute Hepatic Failure side effect. The patient was hospitalized.
Tazocin Side Effect Report#9275144
Dermatitis Bullous, Hypersensitivity, Necrosis
This report suggests a potential Tazocin Dermatitis Bullous side effect(s) that can have serious consequences. A 61-year-old female patient (weight: NA) from CN was diagnosed with the following symptoms/conditions: prophylaxis and used Tazocin (dosage: Unk) starting 201303. After starting Tazocin the patient began experiencing various side effects, including: Dermatitis Bullous, Hypersensitivity, NecrosisAdditional drugs used concurrently: NA.The patient was hospitalized. Although Tazocin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dermatitis Bullous, may still occur.
Tazocin Side Effect Report#9216882
Heart Rate Increased, Swelling
This Heart Rate Increased problem was reported by a health professional from SG. A 53-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Tazocin (dosage: NA). The following drugs were being taken at the same time:
  • Ketorolac
When using Tazocin, the patient experienced the following unwanted symptoms/side effects: Heart Rate Increased, SwellingAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Heart Rate Increased, may become evident only after a product is in use by the general population.
Tazocin Side Effect Report#9204199
Anaphylactic Reaction, Pulseless Electrical Activity
This Anaphylactic Reaction side effect was reported by a physician from GB. A 65-year-old female patient (weight:NA) experienced the following symptoms/conditions: infection,renal transplant,cytomegalovirus gastroenteritis.The patient was prescribed Tazocin (drug dosage: Unk), which was initiated on
Apr 17, 2012. Concurrently used drugs:
  • Tacrolimus
  • Valganciclovir
.After starting to take Tazocin the consumer reported adverse symptoms, such as: Anaphylactic Reaction, Pulseless Electrical ActivityThese side effects may potentially be related to Tazocin.
Tazocin Side Effect Report#9157162
Dermatitis Bullous, Dermatitis Exfoliative, Hypotension, Sepsis, Respiratory Failure, Anaemia
This is a report of a 85-year-old female patient (weight: NA) from IT, suffering from the following health symptoms/conditions: urinary tract infection,hyperuricaemia, who was treated with Tazocin (dosage: 2.25 G, 3x/day, start time: 201302), combined with:
  • Zyloric (300 Mg, 1x/day)
  • Omeprazole (20 Mg, Daily)
  • Metronidazole (750 Mg, Daily)
  • Aldactone (25 Mg, Daily)
  • Pariet (20 Mg, Daily)
  • Potassion (Unk)
  • Kcl-retard (600 Mg, Daily)
  • Lasix For Injection (40 Mg, Daily)
and developed a serious reaction and side effect(s): Dermatitis Bullous, Dermatitis Exfoliative, Hypotension, Sepsis, Respiratory Failure, Anaemia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Tazocin treatment in female patients, resulting in Dermatitis Bullous side effect. The patient was hospitalized.
Tazocin Side Effect Report#9100989
Lip Swelling, Tongue Oedema
This report suggests a potential Tazocin Lip Swelling side effect(s) that can have serious consequences. A 34-year-old female patient (weight: NA) from SE was diagnosed with the following symptoms/conditions: sepsis and used Tazocin (dosage: Unk) starting
May 11, 2012. After starting Tazocin the patient began experiencing various side effects, including: Lip Swelling, Tongue OedemaAdditional drugs used concurrently:
  • Oxynorm (Unk)
  • Oxycontin (Unk)
  • Panodil (Unk)
The patient was hospitalized. Although Tazocin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Lip Swelling, may still occur.
Tazocin Side Effect Report#9100988
Lip Swelling, Tongue Oedema
This Lip Swelling problem was reported by a physician from SE. A 34-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: sepsis. On
May 11, 2012 this consumer started treatment with Tazocin (dosage: Unk). The following drugs were being taken at the same time:
  • Oxynorm (Unk)
  • Oxycontin (Unk)
  • Panodil (Unk)
When using Tazocin, the patient experienced the following unwanted symptoms/side effects: Lip Swelling, Tongue OedemaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Lip Swelling, may become evident only after a product is in use by the general population.
Tazocin Side Effect Report#9031484
Neurotoxicity, Encephalopathy
This Neurotoxicity side effect was reported by a physician from TW. A 87-year-old male patient (weight:NA) experienced the following symptoms/conditions: escherichia infection,escherichia urinary tract infection.The patient was prescribed Tazocin (drug dosage: 2.25 G,1x/12 Hr), which was initiated on NS. Concurrently used drugs: NA..After starting to take Tazocin the consumer reported adverse symptoms, such as: Neurotoxicity, EncephalopathyThese side effects may potentially be related to Tazocin. The patient was hospitalized.
Tazocin Side Effect Report#9030315
Acute Hepatic Failure, Cholestasis
This is a report of a 62-year-old male patient (weight: NA) from GB, suffering from the following health symptoms/conditions: pneumonia, who was treated with Tazocin (dosage: 4.5 G, 2x/day, start time:
Nov 07, 2012), combined with:
  • Vancomycin (1 G, Unk)
  • Novorapid (10 Iu, Unk)
  • Gabapentin (100 Mg, Unk)
  • Codeine Phosphate (15-30mg, 4 Times A Day)
  • Lanthanum Carbonate (750 Mg, 3x/day Morning, Midday, Evening)
  • Insulin
  • Epaderm (1 Df, 3x/day Morning, Midday And Evening)
  • Aspirin (75 Mg, 1x/day Morning)
and developed a serious reaction and side effect(s): Acute Hepatic Failure, Cholestasis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Tazocin treatment in male patients, resulting in Acute Hepatic Failure side effect. The patient was hospitalized.


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The appearance of Tazocin on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Tazocin reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Tazocin Safety Alerts, Active Ingredients, Usage Information

    NDC0591-0395
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NamePentazocine and naloxone
    NamePentazocine hydrochloride and naloxone hydrochloride
    Dosage FormTABLET
    RouteORAL
    On market since19970121
    LabelerWatson Laboratories, Inc.
    Active Ingredient(s)NALOXONE HYDROCHLORIDE; PENTAZOCINE HYDROCHLORIDE
    Strength(s).5; 50
    Unit(s)mg/1; mg/1
    Pharma ClassCompetitive Opioid Antagonists [MoA],Partial Opioid Agonist/Antagonist [EPC],Partial Opioid Agonists

    More About Tazocin

    Side Effects reported to FDA: 280

    Tazocin safety alerts: No

    Reported deaths: 35

    Reported hospitalizations: 114

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