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Review Temozolomide Safety Reports submitted to FDA

Total Temozolomide reports: 767.
Temozolomide FDA safety alerts: No.
Reported deaths: 151    Reported hospitalizations: 599.
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FDA Reported Temozolomide Side Effects: platelet count decreased, asthenia, thrombocytopenia, pyrexia, white blood cell count decreased, dehydration, pulmonary embolism, confusional state, nausea, convulsion, headache.
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Temozolomide Side Effects Report #5466698-4
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Sept 24, 2007. Female patient, weighting 170.9 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: nervous system disorder, neutrophil count decreased, platelet count decreased, white blood cell count decreased. TEMOZOLOMIDE dosage: 2050 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5466705-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 24, 2007. Female patient, weighting 260.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, dizziness, hypotension, nausea, pyrexia, vomiting. TEMOZOLOMIDE dosage: 2760 MG. During the same period patient was treated with JANUVIA. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5466713-8
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Sept 24, 2007. Female patient, weighting 244.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: abdominal pain. TEMOZOLOMIDE dosage: 7525 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5467664-5
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Sept 18, 2007. Female patient, 26 years of age, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: astrocytoma, coma, confusional state, convulsion, decubitus ulcer, electroencephalogram abnormal, encephalitis, eschar, febrile bone marrow aplasia. TEMOZOLOMIDE dosage: 600 MG/M2; QD; PO. During the same period patient was treated with INEXIUM, MEDROL. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5467689-X
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Sept 13, 2007. Male patient, 59 years of age, weighting 197.1 lb, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: catheter site infection, gastrointestinal infection. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with FELODIPINE, LEVOTHYROXINE, PHENYTOIN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5469450-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 25, 2007. Female patient, weighting 154.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: anorexia, asthenia, balance disorder, deep vein thrombosis, fall, gait disturbance, grip strength decreased, memory impairment, mental disorder. TEMOZOLOMIDE dosage: 2625 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5469742-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Sept 26, 2007. Male patient, weighting 167.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: convulsion, diabetic hyperosmolar coma. TEMOZOLOMIDE dosage: 1260 MG. During the same period patient was treated with DILANTIN, KEPPRA, DECADRON. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5469777-0
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Sept 26, 2007. Female patient, 59 years of age, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: antinuclear antibody positive, aplastic anaemia, bone marrow failure, ecchymosis, malignant neoplasm progression, metastases to liver, metastases to soft tissue, metastases to spleen, skin haemorrhage. TEMOZOLOMIDE dosage: 140 MG DAILY PO. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5470209-7
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Sept 17, 2007. Male patient, 58 years of age, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure. TEMOZOLOMIDE dosage: unknown. Patient died.


Temozolomide Side Effects Report #5470275-9
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Sept 17, 2007. Male patient, 70 years of age, weighting 166.0 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. TEMOZOLOMIDE dosage: PO; 400 MG; QD; PO. During the same period patient was treated with ZOCOR, ASPIRIN, FLOMAX, LISINOPRIL, GLYBURIDE, GLUCOPHAGE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5473200-X
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Sept 19, 2007. Male patient, 59 years of age, weighting 197.1 lb, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: device related infection, gastrointestinal disorder. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with FELODIPINE, LEVOTHYROXINE, PHENYTOIN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5474120-7
TEMOZOLOMIDE problem was reported by a Health Professional from UNITED STATES on Sept 27, 2007. Male patient, weighting 154.3 lb, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, disease progression. TEMOZOLOMIDE dosage: PO 140MG (DAY1). During the same period patient was treated with EFFEXOR, PEPCID, DEXAMETHASONE, POTASSIUM CHLORIDE, KEPPRA, TRAZODONE, PROVIGIL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5474498-4
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Sept 28, 2007. Female patient, weighting 156.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: hallucination, metabolic encephalopathy, oral intake reduced, somnolence, visual disturbance. TEMOZOLOMIDE dosage: 135 MG. During the same period patient was treated with ASPIRIN, COLACE, DECADRON, DIGOXIN, DUONEBS, LASIX, LEVAQUIN, LIPITOR. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5474610-7
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Sept 21, 2007. Female patient, 64 years of age, weighting 260.1 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: anorexia, asthenia, blood albumin decreased, dizziness, haemoglobin abnormal, hypotension, nausea, neutrophil count abnormal, platelet count decreased. TEMOZOLOMIDE dosage: 75 MG/M2;. During the same period patient was treated with JANUVIA. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5474844-1
Physician from ISRAEL reported TEMOZOLOMIDE problem on Sept 19, 2007. Female patient, 68 years of age, weighting 200.6 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: anxiety, asthenia, balance disorder, dizziness, encephalitis viral, fatigue, headache, hypersensitivity, lethargy. TEMOZOLOMIDE dosage: 155 MG; QD; PO. During the same period patient was treated with AMLODIPINE, ATENOLOL, LEVOTHYROXINE, OXAZEPAM, CARBAMAZEPINE, ENOXAPARIN, DEXAMETHASONE, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5407134-3
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 03, 2007. Male patient, weighting 149.9 lb, was treated with TEMOZOLOMIDE. TEMOZOLOMIDE dosage: 700 MG. Patient died on 10/25/2006.

Temozolomide Side Effects Report #5407150-1
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 03, 2007. Female patient, weighting 157.6 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, pancytopenia, transfusion reaction. TEMOZOLOMIDE dosage: 1900 MG. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5407157-4
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 03, 2007. Female patient, weighting 163.4 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. TEMOZOLOMIDE dosage: 3420 MG. Patient recovered.

Temozolomide Side Effects Report #5407492-X
Physician from BELGIUM reported TEMOZOLOMIDE problem on July 25, 2007. Male patient, 60 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood chloride decreased, blood lactate dehydrogenase increased, blood potassium increased, blood urea increased, dyspnoea, gamma-glutamyltransferase increased, haematocrit decreased. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with ZANTAC, MEDROL, LASIX, BACTRIM DS. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5407503-1
TEMOZOLOMIDE problem was reported by a Physician from ISRAEL on July 26, 2007. Female patient, 72 years of age, weighting 132.3 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: activities of daily living impaired, asthenia, bedridden, cognitive disorder, confusional state, infection, memory impairment, platelet count decreased, pyrexia. TEMOZOLOMIDE dosage: unknown. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5407933-8
Health Professional from UNITED STATES reported TEMOZOLOMIDE problem on July 27, 2007. Male patient was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: dry skin, rash, skin exfoliation. TEMOZOLOMIDE dosage: PO; 150 MG/M2. Patient recovered.

Temozolomide Side Effects Report #5408228-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 06, 2007. Male patient, weighting 238.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pyrexia. TEMOZOLOMIDE dosage: 4760 MG. During the same period patient was treated with ENOXAPARIN, DEXACORT, ENOLADEX, NORMITEN, RESPRIM, SIMOVIL, TEGRETOL, ZANTAB. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5408290-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 06, 2007. Male patient, weighting 210.5 lb, was treated with TEMOZOLOMIDE. TEMOZOLOMIDE dosage: 2240 MG. Patient was hospitalized. Patient died on 12/04/2006.

Temozolomide Side Effects Report #5408335-0
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 06, 2007. Female patient, weighting 174.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood potassium decreased, blood pressure systolic increased, dehydration, neutrophil count decreased, orthostatic hypotension, thrombocytopenia. TEMOZOLOMIDE dosage: 5805 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5408337-4
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 06, 2007. Female patient, weighting 174.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood potassium decreased, blood pressure systolic increased, neutrophil count decreased, orthostatic hypotension, thrombocytopenia, urinary tract infection. TEMOZOLOMIDE dosage: 5805 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5408339-8
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 06, 2007. Female patient, weighting 107.0 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. TEMOZOLOMIDE dosage: 3300 MG. Patient recovered.

Temozolomide Side Effects Report #5408374-X
Physician from FRANCE reported TEMOZOLOMIDE problem on July 31, 2007. Male patient, 64 years of age, weighting 231.5 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, renal failure. TEMOZOLOMIDE dosage: 320 MG; QD;. During the same period patient was treated with COVERSYL, ENALAPRIL MALEATE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5409548-4
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 07, 2007. Female patient, weighting 200.6 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: balance disorder, dizziness, fatigue, headache, malaise, pyrexia. TEMOZOLOMIDE dosage: 2945 MG. During the same period patient was treated with AMLODIPINE, ATENOLOL, LEVOTHYROXINE, OXAZAPAM. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5409549-6
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 07, 2007. Male patient, weighting 162.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, small intestinal obstruction. TEMOZOLOMIDE dosage: 2380 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5409551-4
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 07, 2007. Female patient, weighting 110.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, fluid intake reduced, hyperglycaemia, hyponatraemia, vomiting. TEMOZOLOMIDE dosage: 2200 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5409553-8
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 07, 2007. Female patient, weighting 265.0 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. TEMOZOLOMIDE dosage: 4785 MG. Patient recovered.

Temozolomide Side Effects Report #5409658-1
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 08, 2007. Male patient, weighting 210.5 lb, was treated with TEMOZOLOMIDE. TEMOZOLOMIDE dosage: unknown. Patient was hospitalized. Patient died on 12/04/2006.

Temozolomide Side Effects Report #5409693-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 08, 2007. Female patient, weighting 157.6 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, pancytopenia, transfusion reaction. TEMOZOLOMIDE dosage: unknown. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5410964-5
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 09, 2007. Female patient, weighting 127.4 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: body temperature increased, contusion, haemoglobin decreased, red blood cell count decreased, thrombocytopenia. TEMOZOLOMIDE dosage: unknown. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5411145-1
Physician from BELGIUM reported TEMOZOLOMIDE problem on July 30, 2007. Male patient, 60 years of age, weighting 191.8 lb, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood chloride decreased, blood lactate dehydrogenase increased, blood potassium increased, blood urea increased, dyspnoea, embolism, gamma-glutamyltransferase increased. TEMOZOLOMIDE dosage: 175 MG; QD; PO. During the same period patient was treated with ZANTAC, MEDROL, LASIX, BACTRIM DS, ALDACTONE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5411940-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 10, 2007. Male patient, weighting 192.4 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: brain oedema, confusional state, convulsion, disease progression, postictal state, radiation injury, somnolence, tremor. TEMOZOLOMIDE dosage: 150 MG. During the same period patient was treated with HERBAL AGENTS. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5411941-0
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 10, 2007. Male patient, weighting 192.4 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: brain oedema, confusional state, convulsion, disease progression, postictal state, radiation injury, somnolence, tremor. TEMOZOLOMIDE dosage: 150 MG. During the same period patient was treated with HERBAL AGENTS. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5411956-2
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 10, 2007. Male patient, weighting 249.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: confusional state. TEMOZOLOMIDE dosage: 1360 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5413331-3
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Aug 07, 2007. Male patient, 75 years of age, weighting 162.3 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: ileus. TEMOZOLOMIDE dosage: 75 MG/M2; PO. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5414762-8
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Aug 06, 2007. Female patient, 65 years of age, weighting 174.2 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood potassium decreased, dehydration, hypotension, neutrophil count decreased, orthostatic hypotension, thrombocytopenia, urinary tract infection. TEMOZOLOMIDE dosage: 135 MG;QD;PO. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5414798-7
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Aug 03, 2007. Female patient, 79 years of age, weighting 157.6 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, pancytopenia, sick sinus syndrome. TEMOZOLOMIDE dosage: 75 MG/M2; QD; PO; 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5416455-X
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 13, 2007. Male patient, weighting 162.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: small intestinal obstruction. TEMOZOLOMIDE dosage: 2380 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5416467-6
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 13, 2007. Female patient, weighting 157.6 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, disease progression, transfusion reaction. TEMOZOLOMIDE dosage: 1900 MG. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5417929-8
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Aug 09, 2007. Male patient, 64 years of age, weighting 149.9 lb, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pancytopenia, septic shock. TEMOZOLOMIDE dosage: 140 MG; QD; PO. During the same period patient was treated with BACTRIM DS, ZOFRAN, KEPPRA. Patient died on 06/07/2007.

Temozolomide Side Effects Report #5419189-0
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 15, 2007. Female patient, weighting 188.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: chest pain, computerised tomogram abnormal, cough, sputum culture positive, sputum discoloured, staphylococcal infection. TEMOZOLOMIDE dosage: 200 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5419244-5
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Aug 08, 2007. Male patient, 75 years of age, weighting 162.3 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, ileus. TEMOZOLOMIDE dosage: 75 MG/M2; ; PO. During the same period patient was treated with COLACE, TOBRADEX, KEPPRA, GLYBURIDE, DICLUCAN, MYCOSTATIN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5419256-1
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Aug 06, 2007. Male patient, 88 years of age, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: hypoxia, lung infiltration, pneumonitis, pulmonary toxicity. TEMOZOLOMIDE dosage: 75 MG/M2; QD;, 200 MG/M2; QD;. Patient recovered.

Temozolomide Side Effects Report #5420943-X
TEMOZOLOMIDE problem was reported by a Health Professional from UNITED STATES on Aug 17, 2007. Female patient, weighting 130.1 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, diverticulitis. TEMOZOLOMIDE dosage: 160MG, QD X 7, QO WEEK. During the same period patient was treated with SUNITINIB MALATE, LOTREL, ONDANSETRON, METAMUCIL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5421253-7
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Aug 13, 2007. Female patient, 65 years of age, weighting 174.2 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: dehydration, hypotension, neutrophil count decreased, orthostatic hypotension, thrombocytopenia, urinary tract infection. TEMOZOLOMIDE dosage: 135 MG; QD; PO. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5421881-9
TEMOZOLOMIDE problem was reported by a Physician from UNITED KINGDOM on Aug 09, 2007. Male patient, 40 years of age, weighting 181.7 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: anaemia, blood lactate dehydrogenase increased, hyperbilirubinaemia, nausea, vomiting. TEMOZOLOMIDE dosage: 320 MG;. During the same period patient was treated with DOMPERIDONE, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5421908-4
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 21, 2007. Female patient, weighting 136.7 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: haemoglobin decreased, leukopenia, thrombocytopenia. TEMOZOLOMIDE dosage: 2760 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5421909-6
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2007. Male patient, weighting 249.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: confusional state. TEMOZOLOMIDE dosage: 1360 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5422083-2
Pharmacist from UNITED STATES reported TEMOZOLOMIDE problem on Aug 21, 2007. Male patient, 62 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: leukopenia, thrombocytopenia. TEMOZOLOMIDE dosage: 200MG EVERY DAY PO. Patient recovered.

Temozolomide Side Effects Report #5422410-6
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Aug 13, 2007. Female patient, 56 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pneumonia. TEMOZOLOMIDE dosage: 120 MG; QD; PO, 225 MG; QD; PO. During the same period patient was treated with METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5422609-9
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Aug 10, 2007. Female patient, 79 years of age, weighting 157.6 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, bone marrow failure, disease progression, pancytopenia, sick sinus syndrome. TEMOZOLOMIDE dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5422933-X
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Aug 13, 2007. Female patient, 26 years of age, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: astrocytoma, coma, confusional state, convulsion, encephalitis, febrile bone marrow aplasia, fungal infection, hemiplegia, immunosuppression. TEMOZOLOMIDE dosage: 600 MG/M2; QD; PO. During the same period patient was treated with NEXIUM, MEDROL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5422975-4
Health Professional from ISRAEL reported TEMOZOLOMIDE problem on Aug 14, 2007. Female patient, 69 years of age, weighting 112.4 lb, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, cardiac failure congestive, diabetes mellitus inadequate control, meningitis bacterial, respiratory disorder, upper respiratory tract infection. TEMOZOLOMIDE dosage: 115 MG;QD;. During the same period patient was treated with CILAZAPRIL, DILTIAZEM, EZETIMIBE, FAMOTIDINE, GLYBURIDE, METFORMIN, DEXAMETHASONE, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5423537-5
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Aug 21, 2007. Female patient, weighting 134.0 lb, was diagnosed with malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pneumonia, white blood cell count decreased. TEMOZOLOMIDE dosage: 170MG, QD X 7, QO WEEK. During the same period patient was treated with SUNITIB MALATE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5426056-5
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 24, 2007. Female patient, weighting 136.7 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, leukopenia, thrombocytopenia. TEMOZOLOMIDE dosage: 2760 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5426061-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Female patient, weighting 110.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, anxiety, asthenia, blood bilirubin increased, dehydration, fluid intake reduced, hyperglycaemia, hyponatraemia, nausea. TEMOZOLOMIDE dosage: 2200 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5428877-1
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Aug 16, 2007. Male patient, 40 years of age, weighting 181.7 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: anaemia, blood bilirubin increased, blood lactate dehydrogenase increased, dizziness, nausea, vomiting. TEMOZOLOMIDE dosage: 320 MG;. During the same period patient was treated with DOMPERIDONE, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5429297-6
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 27, 2007. Female patient, weighting 165.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: body temperature increased, neutrophil count decreased, pharyngolaryngeal pain. TEMOZOLOMIDE dosage: 5670 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5434724-4
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 28, 2007. Female patient, weighting 136.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: leukopenia, neutropenia, thrombocytopenia. TEMOZOLOMIDE dosage: 1650 MG. During the same period patient was treated with DECADRON, KEPPRA, SEPTRA DS. Patient recovered.

Temozolomide Side Effects Report #5435766-5
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 28, 2007. Male patient, weighting 166.0 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. TEMOZOLOMIDE dosage: 1600 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5441513-3
Pharmacist from FRANCE reported TEMOZOLOMIDE problem on Aug 24, 2007. Female patient, 70 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: aplasia, haemorrhage, thrombocytopenic purpura. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with FUNGIZONE, PARACETAMOL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5441565-0
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Aug 20, 2007. Male patient, 64 years of age, weighting 231.5 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: renal failure. TEMOZOLOMIDE dosage: 320 MG; QD; PO. During the same period patient was treated with COVERSYL, ENALAPRIL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5441826-5
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Aug 22, 2007. Male patient, 70 years of age, weighting 166.0 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. TEMOZOLOMIDE dosage: PO, 1600 MG, PO. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5443086-8
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Aug 27, 2007. Male patient, 70 years of age, weighting 166.0 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. TEMOZOLOMIDE dosage: PO; ,400 MG; PO. During the same period patient was treated with ZOCOR, ASPIRIN, FLOMAX, LISINOPRIL, GLYBURIDE, GLUCOPHAGE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5443325-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Aug 31, 2007. Female patient, weighting 136.7 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, leukopenia, thrombocytopenia. TEMOZOLOMIDE dosage: 2760 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5443339-3
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 31, 2007. Male patient, weighting 167.6 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: erythema, eye swelling, herpes zoster ophthalmic. TEMOZOLOMIDE dosage: 7100 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5444125-0
Physician from ISRAEL reported TEMOZOLOMIDE problem on Aug 23, 2007. Female patient, 75 years of age, weighting 110.2 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, blood bilirubin increased, dehydration, hyperglycaemia, hyponatraemia, transaminases increased, vomiting. TEMOZOLOMIDE dosage: 110 MG; QD. During the same period patient was treated with RISPERDAL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5378393-0
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on July 02, 2007. Female patient, weighting 336.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: fatigue, hypokalaemia, weight decreased. TEMOZOLOMIDE dosage: 1800 MG. During the same period patient was treated with COMPAZINE, KEPPRA. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5378515-1
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on June 25, 2007. Female patient was diagnosed with metastases to central nervous system and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, dyspnoea, headache, leukopenia, neutropenia, pneumonia, sepsis, thrombocytopenia. TEMOZOLOMIDE dosage: 150 MG/M2; PO. During the same period patient was treated with LOMUSTINE. Patient died.

Temozolomide Side Effects Report #5378542-4
TEMOZOLOMIDE problem was reported by a Physician from UNITED KINGDOM on June 25, 2007. Female patient was diagnosed with metastases to central nervous system and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, cerebral haemorrhage. TEMOZOLOMIDE dosage: 150 MG/M2. During the same period patient was treated with LOMUSTINE. Patient died.

Temozolomide Side Effects Report #5378593-X
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on June 25, 2007. Female patient was diagnosed with metastases to central nervous system and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, headache. TEMOZOLOMIDE dosage: 150 MG/M2;. During the same period patient was treated with LOMUSTINE. Patient died.

Temozolomide Side Effects Report #5379845-X
TEMOZOLOMIDE problem was reported by a Health Professional from JAPAN on June 25, 2007. Male patient, 65 years of age, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: convulsion, glioblastoma multiforme, malignant neoplasm progression, necrosis, radiation injury. TEMOZOLOMIDE dosage: unknown. Patient died on 06/08/2007.

Temozolomide Side Effects Report #5382914-1
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 05, 2007. Female patient, weighting 132.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, bedridden, confusional state, platelet count decreased, pyrexia, white blood cell count decreased. TEMOZOLOMIDE dosage: 1150 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5383069-X
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on June 25, 2007. Male patient was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pancytopenia. TEMOZOLOMIDE dosage: 75 MG/M2; QD; PO. Patient died.

Temozolomide Side Effects Report #5383070-6
Physician from FRANCE reported TEMOZOLOMIDE problem on June 29, 2007. Female patient, 65 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: aphasia, thrombocytopenia. TEMOZOLOMIDE dosage: 75 MG/M2; QD;PO. Patient recovered.

Temozolomide Side Effects Report #5383641-7
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on June 28, 2007. Female patient, 66 years of age, weighting 149.9 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: pleural effusion, pneumonitis. TEMOZOLOMIDE dosage: 4725 MG; PO. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5385156-9
Physician from GERMANY reported TEMOZOLOMIDE problem on July 02, 2007. Female patient, 59 years of age, weighting 119.0 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: gastrointestinal disorder, pancreatitis. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with PANTOZOL, NORMOFUNDIN, FRAXIPARIN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5385245-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on July 09, 2007. Female patient, weighting 147.7 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, chills, hypokalaemia, intracranial tumour haemorrhage, leukopenia, neutropenia, pseudomonal bacteraemia, pyrexia, thrombocytopenia. TEMOZOLOMIDE dosage: 3120 MG. During the same period patient was treated with NEWCASTLE VIRUSECTION, RESPRIM. Patient was hospitalized. Patient died on 05/24/2007.

Temozolomide Side Effects Report #5385247-2
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 09, 2007. Male patient, weighting 238.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: hypersensitivity, pyrexia. TEMOZOLOMIDE dosage: 4760 MG. During the same period patient was treated with CLEXANE, DEXACORT, ENOLADEX, NORMITEN, RESPRIM, SIMOVIL, TEGRETOL, ZENTAC. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5385252-6
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on July 09, 2007. Female patient, weighting 102.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: headache, nausea, subdural effusion, vomiting. TEMOZOLOMIDE dosage: 770 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5385256-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 09, 2007. Male patient, weighting 198.4 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: neutrophil count decreased. TEMOZOLOMIDE dosage: 320 MG. During the same period patient was treated with LEUCOVORIN CALCIUM, METHOTREXATE, ATENOLOL, ATIVAN, BACTRIM DS, COLACE, DULCOLAX, KEPPRA. Patient recovered.

Temozolomide Side Effects Report #5387185-8
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on July 03, 2007. Male patient, 68 years of age, was diagnosed with mixed oligo-astrocytoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: abasia, agitation, confusional state, delirium, hallucination, visual, poor quality sleep, restlessness. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with DILANTIN KAPSEAL, DILANTIN KAPSEAL, PROTONIX, TERAZOSIN, COLACE, VITAMIN CAP, ZOFRAN. Patient recovered.

Temozolomide Side Effects Report #5387407-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 11, 2007. Female patient, weighting 160.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, platelet count decreased. TEMOZOLOMIDE dosage: 4160 MG. During the same period patient was treated with ALTACE, DECADRON, INSULIN, KYTRIL, SYNTHROID. Patient recovered.

Temozolomide Side Effects Report #5387632-1
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on July 12, 2007. Male patient, 75 years of age, weighting 165.3 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis. TEMOZOLOMIDE dosage: 150 MG/DAY, PO. During the same period patient was treated with FRAGMIN, ALLOPURINOL, BISACODYL, COLACE, DEXAMETHASONE, FOLIC ACID. Patient recovered.

Temozolomide Side Effects Report #5387691-6
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 12, 2007. Female patient, weighting 173.9 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: dehydration, gait disturbance, hemiparesis, nausea, vomiting. TEMOZOLOMIDE dosage: unknown. Patient recovered.

Temozolomide Side Effects Report #5389294-6
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on July 03, 2007. Female patient, 66 years of age, weighting 149.9 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pleural effusion, pneumonia, pneumonitis. TEMOZOLOMIDE dosage: 725 MG; PO; PO. During the same period patient was treated with BACTRIM. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5389346-0
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 13, 2007. Male patient, weighting 188.5 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: multi-organ failure, neutropenia, pneumonia pneumococcal, renal failure acute, respiratory failure, septic shock. TEMOZOLOMIDE dosage: 1320 MG. During the same period patient was treated with ASPIRIN, AVELOX, DEXAMETHASONE, KEPPRA, LISINOPRIL, LOPRESSOR, NEXIUM, ZOFRAN. Patient recovered.

Temozolomide Side Effects Report #5389570-7
TEMOZOLOMIDE problem was reported by a Physician from UNITED KINGDOM on July 04, 2007. Male patient, 34 years of age, was diagnosed with malignant glioma, neoplasm recurrence and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: coordination abnormal, dysphasia, hypoaesthesia, neuropathy, speech disorder. TEMOZOLOMIDE dosage: 440 MG; QD;. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5390184-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 16, 2007. Female patient, weighting 102.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: headache, nausea, subdural effusion, vomiting. TEMOZOLOMIDE dosage: 770 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5390186-7
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on July 16, 2007. Female patient, weighting 143.0 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, feeling abnormal, headache, malaise, urinary tract infection. TEMOZOLOMIDE dosage: 3770 MG. During the same period patient was treated with CIPROFLOXACIN, COLACE, DECADRON, ISOTONIX, KEPPRA, PRILOSEC, TYLENOL. Patient recovered.

Temozolomide Side Effects Report #5390187-9
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 16, 2007. Female patient, weighting 150.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pyrexia. TEMOZOLOMIDE dosage: 4725 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5392150-0
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on July 18, 2007. Male patient, weighting 195.7 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. TEMOZOLOMIDE dosage: 3255 MG. Patient was hospitalized. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5392152-4
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on July 18, 2007. Female patient, weighting 150.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pyrexia. TEMOZOLOMIDE dosage: 4725 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5392175-5
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on July 17, 2007. Male patient, 75 years of age, weighting 165.3 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis. TEMOZOLOMIDE dosage: 150 MG/DAY, PO. During the same period patient was treated with FRAGMIN, ALLOPURINOL, BISACODYL, COLACE, DEXAMETHASONE, FOLIC ACID. Patient recovered.

Temozolomide Side Effects Report #5392799-5
Physician from GERMANY reported TEMOZOLOMIDE problem on July 13, 2007. Male patient, 67 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: apparent life threatening event, partial seizures, status epilepticus. TEMOZOLOMIDE dosage: 200 MG/M2. Patient was hospitalized. Patient died on 05/07/2007.

Temozolomide Side Effects Report #5392812-5
TEMOZOLOMIDE problem was reported by a Pharmacist from FRANCE on July 11, 2007. Female patient, 70 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: aplasia, haemorrhage, purpura, thrombocytopenia. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with FUNGIZONE, PARACETAMOL. Patient recovered.

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