Temozolomide Side Effects
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Temozolomide Safety Reports reported to FDA
Total Temozolomide reports: 434.Temozolomide FDA safety alerts: No.
Reported deaths: 98 Reported hospitalizations: 307.
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Reported Temozolomide Side Effects: platelet count decreased, asthenia, thrombocytopenia, pyrexia, white blood cell count decreased, dehydration, pulmonary embolism, confusional state, nausea, convulsion, headache.
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Showing 1-50 of 434 Next >
Temozolomide Side Effects Report #5254862-9Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Mar 02, 2007. Female patient, weighting 129.0 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, aspergillosis, febrile neutropenia, pneumonia, septic shock, streptococcal infection. TEMOZOLOMIDE dosage: 1159 MG. During the same period patient was treated with VALPROIC ACID, DEXAMETHASONE. Patient was hospitalized. Patient died on 12/23/2006.
Temozolomide Side Effects Report #5255744-9
TEMOZOLOMIDE problem was reported by a Physician from JAPAN on Feb 22, 2007. Male patient, 58 years of age, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: respiratory failure. TEMOZOLOMIDE dosage: unknown. Patient recovered.
Temozolomide Side Effects Report #5255850-9
Physician from JAPAN reported TEMOZOLOMIDE problem on Feb 22, 2007. Male patient, 58 years of age, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: respiratory failure. TEMOZOLOMIDE dosage: unknown. Patient recovered.
Temozolomide Side Effects Report #5256036-4
TEMOZOLOMIDE problem was reported by a Pharmacist from UNITED STATES on Mar 02, 2007. Female patient, 77 years of age, weighting 200.0 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, mucosal inflammation. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with SUNITINIB, SKELAXIN, CLARINEX, DIOVAN, SEREVENT, PEPCID, QUININE, NEXIUM. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5257049-9
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Feb 26, 2007. Female patient, 74 years of age, weighting 135.1 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: anorexia, aphagia, atelectasis, cognitive disorder, disease progression, haemoglobin decreased, hemiparesis, herpes zoster. TEMOZOLOMIDE dosage: 125 MG;QD;PO. During the same period patient was treated with RADIATION, ZIAC, PROTONIX, AVANDIA, PRANDIN, PHENYTOIN, BACTRIM, XOPENEX. Patient was hospitalized. Patient died on 02/12/2007.
Temozolomide Side Effects Report #5257280-2
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Feb 27, 2007. Male patient, 76 years of age, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: bacteria stool identified, cardiac flutter, confusional state, dehydration, dry skin, epilepsy, fall, grand mal convulsion, malaise. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with ZOPHREN, MEDROL, CIPROFLOXACIN, FLAGYL, DIANTALVIC, NEURONTIN. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5258680-7
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Feb 27, 2007. Female patient was diagnosed with glioblastoma, pneumocystis jiroveci pneumonia, prophylaxis and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood bilirubin increased, hepatic function abnormal, mucosal inflammation, rash, transaminases increased. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with COTRIMOXAZOLE, DEXAMETHASONE, DOMPERIDONE. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5261417-9
TEMOZOLOMIDE problem was reported by a Physician from TURKEY on Feb 28, 2007. Male patient, 44 years of age, weighting 158.7 lb, was diagnosed with malignant glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: haematotoxicity, headache, neutropenia, rash, thrombocytopenia, white blood cell count decreased. TEMOZOLOMIDE dosage: 180 MG;QD;PO. During the same period patient was treated with DEXAMETHASONE, LANSOPRAZOLE. Patient died on 02/24/2007.
Temozolomide Side Effects Report #5262326-1
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Mar 08, 2007. Female patient, weighting 147.7 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: gallbladder disorder, gallbladder pain, nausea, pancytopenia, platelet count decreased, vomiting. TEMOZOLOMIDE dosage: 4750 MG. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5266032-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 13, 2007. Male patient, weighting 163.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: cough, musculoskeletal chest pain, pulmonary embolism. TEMOZOLOMIDE dosage: 290 MG. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5268184-3
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Mar 16, 2007. Female patient, weighting 136.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: leukopenia, neutropenia, thrombocytopenia. TEMOZOLOMIDE dosage: 1650 MG. During the same period patient was treated with DECADRON, KEPPRA, SEPTRA DS. Patient recovered.
Temozolomide Side Effects Report #5268302-7
TEMOZOLOMIDE problem was reported by a Physician from JAPAN on Feb 27, 2007. Male patient, 58 years of age, weighting 180.8 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: cardiac failure, pleural effusion, respiratory failure, upper respiratory tract inflammation, wheezing. TEMOZOLOMIDE dosage: unknown. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5268661-5
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Mar 15, 2007. Female patient, weighting 211.4 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: necrosis, neoplasm progression, nervous system disorder, radiation injury. TEMOZOLOMIDE dosage: 230 MG. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5271361-9
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Mar 05, 2007. Male patient, 54 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: central nervous system necrosis, radiation injury. TEMOZOLOMIDE dosage: unknown. Patient died.
Temozolomide Side Effects Report #5273087-4
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Mar 06, 2007. Male patient, 63 years of age, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood culture positive, convulsion, lower respiratory tract infection, neutropenia, platelet count decreased, pneumonia, staphylococcal infection. TEMOZOLOMIDE dosage: 200 MG;QD;PO. During the same period patient was treated with PROCARBAZINE, VINCRISTINE. Patient was hospitalized. Patient died on 02/01/2007.
Temozolomide Side Effects Report #5273326-X
TEMOZOLOMIDE problem was reported by a Physician from JAPAN on Mar 13, 2007. Male patient, 58 years of age, weighting 180.8 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: cardiac failure, infection, pulmonary embolism, respiratory arrest, respiratory failure, upper respiratory tract inflammation. TEMOZOLOMIDE dosage: unknown. Patient was hospitalized. Patient died on 03/13/2007.
Temozolomide Side Effects Report #5278037-2
Physician from JAPAN reported TEMOZOLOMIDE problem on Mar 15, 2007. Male patient, 58 years of age, weighting 180.8 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: acquired diaphragmatic eventration, blood pressure decreased, cardiac failure, infection, pleural effusion, pulmonary embolism, respiratory arrest, respiratory failure, upper respiratory tract inflammation. TEMOZOLOMIDE dosage: unknown. Patient was hospitalized. Patient died on 03/13/2007.
Temozolomide Side Effects Report #5278361-3
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Mar 15, 2007. Male patient, 76 years of age, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: balance disorder, cardiac flutter, confusional state, dehydration, epilepsy, fall, grand mal convulsion, muscular weakness, neoplasm progression. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with ZOPHREN, MEDROL, SOLUMEDROL, CIFLOX, FLAGYL, DIANTALVIC, NEURONTIN. Patient was hospitalized. Patient died on 03/08/2007.
Temozolomide Side Effects Report #5279894-6
Health Professional from UNITED KINGDOM reported TEMOZOLOMIDE problem on Mar 09, 2007. Male patient, 72 years of age, weighting 115.7 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: activities of daily living impaired, candidiasis, dyspnoea, neutropenic sepsis, pancytopenia. TEMOZOLOMIDE dosage: 320 MG;QD;PO. During the same period patient was treated with ASPIRIN, FERROUS SULPHATE, TEMAZEPAM, SENNA. Patient was hospitalized. Patient died on 09/12/2005.
Temozolomide Side Effects Report #5280008-7
TEMOZOLOMIDE problem was reported by a Health Professional from UNITED STATES on Mar 27, 2007. Male patient, weighting 188.9 lb, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: bowen's disease, squamous cell carcinoma of skin. TEMOZOLOMIDE dosage: 75 MG/ M2 QD PO. During the same period patient was treated with ZONEGRAN, MIRAPEX, BACTRIM DS, COLACE, ZOFRAN. Patient recovered.
Temozolomide Side Effects Report #5287738-1
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 02, 2007. Female patient, weighting 104.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: hypotension, pneumonia, rash, sepsis, sinusitis. TEMOZOLOMIDE dosage: 6295 MG. During the same period patient was treated with PRIMAXIN. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5287838-6
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 03, 2007. Female patient, weighting 136.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: leukopenia, neutropenia, thrombocytopenia. TEMOZOLOMIDE dosage: 1650 MG. During the same period patient was treated with DECADRON, KEPPRA, SEPTRA DS. Patient recovered.
Temozolomide Side Effects Report #5290564-0
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 05, 2007. Male patient, weighting 167.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased. TEMOZOLOMIDE dosage: 2400 MG. During the same period patient was treated with DECADRON, DILANTIN. Patient recovered.
Temozolomide Side Effects Report #5291370-3
TEMOZOLOMIDE problem was reported by a Physician from UNITED KINGDOM on Mar 26, 2007. Male patient, 63 years of age, was diagnosed with malignant glioma, recurrent cancer and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood culture positive, condition aggravated, convulsion, glioblastoma, infection, laboratory test interference, lower respiratory tract infection, neutrophil count decreased. TEMOZOLOMIDE dosage: 200 MG; QD; PO. During the same period patient was treated with PROCARBAZINE, VINCRISTINE. Patient was hospitalized. Patient died on 02/24/2007.
Temozolomide Side Effects Report #5291412-5
Physician from JAPAN reported TEMOZOLOMIDE problem on Mar 16, 2007. Male patient, 58 years of age, weighting 180.8 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, cardiac failure, depressed level of consciousness, infection, pleural effusion, pulmonary embolism, respiratory arrest, respiratory failure, upper respiratory tract inflammation. TEMOZOLOMIDE dosage: unknown. Patient was hospitalized. Patient died on 03/13/2007.
Temozolomide Side Effects Report #5291414-9
TEMOZOLOMIDE problem was reported by a Physician from FRANCE on Mar 22, 2007. Male patient, 57 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: cough, cyanosis, dyspnoea, eosinophil percentage increased, lung disorder, lymphocyte percentage increased, neutrophil percentage decreased. TEMOZOLOMIDE dosage: 250 MG;QD;PO. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5291994-3
Health Professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 06, 2007. Female patient, 72 years of age, weighting 88.18 lb, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: aphasia, asthenia, blood disorder, convulsion, deep vein thrombosis, fatigue, gait disturbance, leukopenia. TEMOZOLOMIDE dosage: 105 MG PO QD. During the same period patient was treated with ATOLENOL, BACTRIM DS, CITALOPRAM HYDROBROMIDE, DECADRON, DEANCIR, DULCOLAX, LACTULOSE. Patient recovered.
Temozolomide Side Effects Report #5292060-3
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 06, 2007. Male patient, weighting 167.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased. TEMOZOLOMIDE dosage: 2400 MG. During the same period patient was treated with DECADRON, DILANTIN. Patient recovered.
Temozolomide Side Effects Report #5292582-5
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Mar 26, 2007. Female patient, 50 years of age, was diagnosed with metastases to central nervous system and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: anaemia, bone marrow failure, haemorrhage, leukopenia, neutropenia, pulmonary fibrosis, pyrexia, thrombocytopenia. TEMOZOLOMIDE dosage: 150 MG/M2;QD;PO. During the same period patient was treated with LOMUSTINE. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5292600-4
TEMOZOLOMIDE problem was reported by a Physician from BELGIUM on Mar 19, 2007. Male patient, 47 years of age, weighting 148.8 lb, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: headache, no therapeutic response, tumour haemorrhage. TEMOZOLOMIDE dosage: 140 MG; QD; PO. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5294464-1
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 09, 2007. Female patient, weighting 104.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: hypotension, hypoxia, lung infection, pneumonia, rash, sepsis, sinusitis. TEMOZOLOMIDE dosage: 6295 MG. During the same period patient was treated with PRIMAXIN. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5294470-7
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 09, 2007. Male patient, weighting 167.3 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased. TEMOZOLOMIDE dosage: 2400 MG. During the same period patient was treated with BENADRYL, DECADRON, KEPPRA. Patient recovered.
Temozolomide Side Effects Report #5295511-3
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Mar 26, 2007. Male patient, 62 years of age, was diagnosed with metastases to central nervous system and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, neutropenia, sepsis, thrombocytopenia. TEMOZOLOMIDE dosage: 150 MG/M2; QD; PO. During the same period patient was treated with LOMUSTINE. Patient died.
Temozolomide Side Effects Report #5296148-2
TEMOZOLOMIDE problem was reported by a Physician from UNITED KINGDOM on Mar 26, 2007. Male patient, 50 years of age, was diagnosed with metastases to central nervous system and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: haemorrhage, thrombocytopenia. TEMOZOLOMIDE dosage: 150 MG/M2; QD; PO. During the same period patient was treated with LOMUSTINE. Patient died.
Temozolomide Side Effects Report #5297343-9
Physician from FRANCE reported TEMOZOLOMIDE problem on Mar 30, 2007. Male patient, 76 years of age, was diagnosed with glioma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: balance disorder, cardiac flutter, confusional state, culture stool positive, culture urine positive, dehydration, epilepsy, fall, glioma. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with ZOPHREN, MEDROL, CIPROFLOXACIN, FLAGYL, DIANTALVIC, NEURONTIN. Patient was hospitalized. Patient died on 03/08/2007.
Temozolomide Side Effects Report #5297837-6
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 13, 2007. Female patient, weighting 137.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: chills, dehydration, epistaxis, neutrophil count decreased, platelet count decreased, syncope, white blood cell count decreased. TEMOZOLOMIDE dosage: 3240 MG. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5298442-8
Physician from UNITED STATES reported TEMOZOLOMIDE problem on Mar 29, 2007. Male patient, 50 years of age, was diagnosed with glioblastoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: hemiparesis, hepatitis b, hepatocellular damage, hepatomegaly, metastases to spine, nervous system disorder. TEMOZOLOMIDE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, TOLTERODINE, LEVETIRACETAM, ATOVAQUONE. Patient recovered.
Temozolomide Side Effects Report #5300228-2
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Mar 30, 2007. Male patient, 49 years of age, weighting 194.0 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood glucose fluctuation, convulsion, headache, loss of consciousness, nausea, oedema, pulmonary embolism, sedation, syncope. TEMOZOLOMIDE dosage: 155 MG; PO. During the same period patient was treated with DECADRON, CRESTOR, DILANTIN, DIOVAN, LASIX, METFORMIN, PEPCID. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5302160-7
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 16, 2007. Male patient, weighting 135.4 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: confusional state, convulsion, pancytopenia. TEMOZOLOMIDE dosage: 1700 MG. During the same period patient was treated with KEPPRA, FLOMAX, KAY CIEL DURA, LAMICTAL, METFORMIN, WARFARIN, ZOCOR. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5302843-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2007. Female patient, weighting 107.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: neutropenia, platelet count decreased. TEMOZOLOMIDE dosage: 2900 MG. During the same period patient was treated with DECADRON. Patient recovered.
Temozolomide Side Effects Report #5302844-0
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 17, 2007. Female patient, weighting 107.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: neutropenia, platelet count decreased, white blood cell count decreased. TEMOZOLOMIDE dosage: 2900 MG. During the same period patient was treated with DECADRON. Patient recovered.
Temozolomide Side Effects Report #5302908-1
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 19, 2007. Female patient, weighting 107.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: neutrophil count decreased, platelet count decreased, white blood cell count decreased. TEMOZOLOMIDE dosage: 2900 MG. During the same period patient was treated with DECADRON. Patient recovered.
Temozolomide Side Effects Report #5302961-5
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 17, 2007. Female patient, weighting 130.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: grand mal convulsion, partial seizures. TEMOZOLOMIDE dosage: 5160 MG. During the same period patient was treated with DECADRON, KEPPRA, NEXIUM, BACTRIM, PAXIL, PROVIGIL, TRICOR, XANAX. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5302963-9
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2007. Male patient, weighting 215.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: ischaemic stroke. TEMOZOLOMIDE dosage: 6720 MG. During the same period patient was treated with DECADRON, KEPPRA, LANTUS, NOVOLOG, ZOCOR, ASPIRIN, BENAZEPRIL HYDROCHLORIDE, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient died on 03/25/2007.
Temozolomide Side Effects Report #5303221-9
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 17, 2007. Male patient, weighting 227.1 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. TEMOZOLOMIDE dosage: 2150 MG. Patient recovered.
Temozolomide Side Effects Report #5303223-2
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2007. Female patient, weighting 107.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: neutrophil count decreased, white blood cell count decreased. TEMOZOLOMIDE dosage: 3000 MG. During the same period patient was treated with DECADRON. Patient recovered.
Temozolomide Side Effects Report #5303224-4
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 17, 2007. Female patient, weighting 107.2 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: neutrophil count decreased, white blood cell count decreased. TEMOZOLOMIDE dosage: 2900 MG. During the same period patient was treated with DECADRON. Patient recovered.
Temozolomide Side Effects Report #5304557-8
TEMOZOLOMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 19, 2007. Male patient, weighting 194.0 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: cellulitis, condition aggravated, depression, diabetes mellitus, gait disturbance, muscular weakness, no therapeutic response, oedema peripheral. TEMOZOLOMIDE dosage: 145 MG. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5304561-X
Consumer or non-health professional from UNITED STATES reported TEMOZOLOMIDE problem on Apr 19, 2007. Male patient, weighting 194.0 lb, was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: asthenia, back pain, cellulitis, condition aggravated, depression, fatigue, mental status changes. TEMOZOLOMIDE dosage: 300 MG. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5304955-2
TEMOZOLOMIDE problem was reported by a Physician from UNITED STATES on Apr 02, 2007. Female patient, 66 years of age, weighting 104.3 lb, was diagnosed with glioblastoma multiforme and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: hypotension, hypoxia, lymphopenia, pneumonia, sepsis, sinusitis. TEMOZOLOMIDE dosage: 75 MG/M2; PO, 65 MG/M2; PO. During the same period patient was treated with PRIMAXIN. Patient was hospitalized. Patient recovered.
Showing 1-50 of 434 Next >
Drug Information: Temozolomide
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601250.html
(te moe zoe' loe mide)About your treatment
Your doctor has ordered the drug temozolomide to help treat your illness. This medication is used to treat brain tumors (astrocytoma). The drug is taken by mouth in capsule form. Your full dose may contain two or more different strengths of temozolomide capsules. Take your dose at bedtime, with a full glass of water, on an empty stomach. Do not chew or open the capsules. If a capsule opens or breaks, be careful not to get the contents on the skin around your eyes, nose, or mouth. Temozolomide is usually given once daily for 5 days. The treatment may be repeated every 28 days.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Temozolomide is in a class of drugs known as imidazotetrazine derivatives. It slows or stops the growth of cancer cells in your body. The length of treatment depends on how well your body responds to the treatment.
Precautions
Before taking temozolomide,
- tell your doctor and pharmacist if you are allergic to temozolomide, dacarbazine, or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including herbal products and vitamins.
- tell your doctor if you have or have ever had kidney or liver disease.
- you should not plan to have children while receiving chemotherapy or for a while after treatments. (Talk to your doctor for further details.) Use a reliable method of birth control to prevent pregnancy. Temozolomide may harm the fetus.
- tell your doctor if you are breast-feeding.
- do not have any vaccinations (e.g., measles or flu shots) without talking to your doctor.
- be aware that temozolomide has been associated with the development of other types of cancer. Talk to your doctor about the potential risk of developing a new cancer.
Side effects
Side effects from temozolomide are common and include:
- nausea
- vomiting
- diarrhea
- stomach pain and cramps
- headache
- numbness
- weakness
- tiredness
- back pain
- dizziness
- difficulty walking or coordinating movement
- vision changes
- loss of appetite
- fever
- swelling of the hands, feet, ankles, or lower legs
- weight gain
- constipation
- discoloration of the skin
- hair loss
- nose bleeds
- fatigue
- confusion
- anxiety
- difficulty falling or staying asleep
- urinary incontinence
- breast pain in women
If you experience any of the following symptoms, call your doctor immediately:
- unusual bleeding or bruising
- rash
- itching
- difficulty breathing or swallowing
- seizures
- infection
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
Storage conditions
Keep temozolomide in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
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