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Ternelin Side Effects

Common Ternelin Side Effects


The most commonly reported Ternelin side effects (click to view or check a box to report):

Alanine Aminotransferase Increased (11)
Aspartate Aminotransferase Increased (11)
Blood Lactate Dehydrogenase Increased (7)
Lymphocyte Stimulation Test Positive (6)
Liver Disorder (6)
Body Temperature Decreased (5)
Blood Pressure Decreased (5)
Blood Pressure Increased (5)
Hypotension (5)
Hepatic Function Abnormal (5)
Diarrhoea (5)
Cardiac Failure (4)
Back Pain (4)
Decreased Appetite (4)
Blood Alkaline Phosphatase Increased (4)
Heart Rate Decreased (4)
Vomiting (4)
Malaise (4)
Gamma-glutamyltransferase Increased (4)
Somnolence (3)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Ternelin Side Effects Reported to FDA

The following Ternelin reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Ternelin on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Meniere's Disease
This is a report of a 57-year-old male patient (weight: NA) from JAPAN, suffering from the following symptoms/conditions: NA, who was treated with Ternelin (ternelin (tizanidine Hydrochloride)) 1 Df (not Specified) (dosage: 2 Df, 1 Df, Bid Oral, start time: NS), combined with:
  • Tegretol (100 Mg Bid Oral)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Meniere's Disease
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Ternelin (ternelin (tizanidine Hydrochloride)) 1 Df (not Specified) treatment in male patients, resulting in meniere's disease side effect.

Pancreatitis Acute
This report suggests a potential Ternelin (ternelin - Tizanidine Hydrochloride) (not Specified) Pancreatitis Acute side effect(s) that can have serious consequences. A 70-year-old male patient (weight: NA) from JAPAN was diagnosed with the following symptoms/conditions: NA and used Ternelin (ternelin - Tizanidine Hydrochloride) (not Specified) (dosage: (df Oral)) starting NS. Soon after starting Ternelin (ternelin - Tizanidine Hydrochloride) (not Specified) the patient began experiencing various side effects, including:
  • Pancreatitis Acute
Drugs used concurrently: NA. Although Ternelin (ternelin - Tizanidine Hydrochloride) (not Specified) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as pancreatitis acute, may still occur.

Urinary Retention, Uterine Operation
This Urinary Retention, Uterine Operation problem was reported by a pharmacist from JAPAN. A 41-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: cervicobrachial syndrome. On May 26, 2010 this consumer started treatment with Ternelin (ternelin) 3 Mg (not Specified) (dosage: 3 Mg Qd Oral). The following drugs were being taken at the same time: NA. When commencing Ternelin (ternelin) 3 Mg (not Specified), the patient experienced the following unwanted symptoms/side effects:
  • Urinary Retention
  • Uterine Operation
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as urinary retention, may become evident only after a product is in use by the general population.

Blood Pressure Increased
This is a report of a 70-year-old female patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: NA and was treated with Ternelin (ternelin - Tizandine Hydrochloride) (not Specified) (dosage: (df Oral)) starting NS. Concurrently used drugs:
  • Luvox ((df Oral))
  • Diovan
  • Doxazosin Mesylate
  • Artist
Soon after that, the consumer experienced the following side effects:
  • Blood Pressure Increased
This opens a possibility that Ternelin (ternelin - Tizandine Hydrochloride) (not Specified) treatment could cause the above reactions, including blood pressure increased, and some female subjects may be more susceptible.


Blood Pressure Increased, Cardiac Failure, Hot Flush, Hypotension, Loss Of Consciousness, Ocular Hyperaemia, Oedema Peripheral
A 46-year-old female patient (weight: NA) from JAPAN with the following symptoms/conditions: cervicobrachial syndrome started Ternelin (ternelin - Tizanidine Hydrochloride) 1 Mg (not Specified) treatment (dosage: (3 Mg Oral)) on May 18, 2009. Soon after starting Ternelin (ternelin - Tizanidine Hydrochloride) 1 Mg (not Specified) treatment, the subject experienced various side effects, including:
  • Blood Pressure Increased
  • Cardiac Failure
  • Hot Flush
  • Hypotension
  • Loss Of Consciousness
  • Ocular Hyperaemia
  • Oedema Peripheral
Concurrently used drugs:
  • Loxoprofen
  • Cefdinir
This finding indicates that some female patients could be more vulnerable to Ternelin (ternelin - Tizanidine Hydrochloride) 1 Mg (not Specified).

Cardiac Failure, Flushing, Hot Flush, Hypotension, Loss Of Consciousness, Ocular Hyperaemia, Oedema Peripheral
A 40-year-old female patient from JAPAN (weight: NA) experienced symptoms, such as: cervicobrachial syndrome and was treated with Ternelin (ternelin - Tizanidine Hydrochloride)(dosage: (3 Mg Oral)). The treatment was initiated on May 18, 2009. After that a consumer reported the following side effect(s):
  • Cardiac Failure
  • Flushing
  • Hot Flush
  • Hypotension
  • Loss Of Consciousness
  • Ocular Hyperaemia
  • Oedema Peripheral
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Ternelin (ternelin - Tizanidine Hydrochloride) efficacy:
  • Loxoprofen
  • Cefdinir


Altered State Of Consciousness, Back Pain, Blood Pressure Decreased, Blood Pressure Increased, Headache, Hypotension, Somnolence, Spinal Compression Fracture
In this report, Ternelin was administered for the following condition: back pain.A female consumer from JAPAN (weight: NA) started Ternelin treatment (dosage: 2 Mg, Qd) on Feb 19, 2009.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Altered State Of Consciousness
  • Back Pain
  • Blood Pressure Decreased
  • Blood Pressure Increased
  • Headache
  • Hypotension
  • Somnolence
  • Spinal Compression Fracture
A possible interaction with other drugs could have contributed to this reaction: NA.The patient was hospitalized.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Ternelin treatment could be related to the listed above side effect(s).

Altered State Of Consciousness, Back Pain, Blood Pressure Decreased, Blood Pressure Increased, Somnolence, Spinal Compression Fracture
This is a report of the following Ternelin side effect(s):
  • Altered State Of Consciousness
  • Back Pain
  • Blood Pressure Decreased
  • Blood Pressure Increased
  • Somnolence
  • Spinal Compression Fracture
A female patient from JAPAN (weight: NA) presented with the following condition: back pain and received a treatment with Ternelin (dosage: 2 Mg, Qd) starting: Feb 19, 2009.The following concurrently used drugs could have generated interactions: NA.The patient was hospitalized.This report suggests that a Ternelin treatment could be associated with the listed above side effect(s).

Glucose Urine Present, Glycosylated Haemoglobin Increased, Proteinuria
This Ternelin report was submitted by a 68-year-old male consumer from JAPAN (weight: NA). The patient was diagnosed with: NA and Ternelin was administered (dosage: Unk) starting: NS. The consumer developed a set of symptoms:
  • Glucose Urine Present
  • Glycosylated Haemoglobin Increased
  • Proteinuria
Other drugs used simultaneously:
  • Voltaren (Unk)
  • Amaryl
Those unexpected symptoms could be linked to a Ternelin treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Electrocardiogram Qt Prolonged
This is a report of a possible correlation between Ternelin use and the following symptoms/side effect(s):
  • Electrocardiogram Qt Prolonged
which could contribute to an assessment of Ternelin risk profile.A 79-year-old male consumer from JAPAN (weight: NA) was suffering from musculoskeletal stiffness,conjunctivitis allergic and was treated with Ternelin (dosage: Unk) starting NS.Other concurrent medications:
  • Zaditen (Unk)
  • Pletal (200 Mg, Qd)
  • Coversyl (4 Mg)
  • Urinorm (50 Mg)
  • Opalmon (15 Mg)


Glucose Urine Present, Glycosylated Haemoglobin Increased, Proteinuria
A 68-year-old male patient from JAPAN (weight: NA) presented with the following symptoms: NA and after a treatment with Ternelin (dosage: Unk) experienced the following side effect(s):
  • Glucose Urine Present
  • Glycosylated Haemoglobin Increased
  • Proteinuria
The treatment was started on NS. Ternelin was used in combination with the following drugs:
  • Voltaren (Unk)
  • Amaryl
This report could alert potential Ternelin consumers.

Glucose Urine Present, Glycosylated Haemoglobin Increased, Proteinuria
In this report, a 68-year-old male patient from JAPAN (weight: NA) was affected by a possible Ternelin side effect.The patient was diagnosed with NA. After a treatment with Ternelin (dosage: Unk, start date: NS), the patient experienced the following side effect(s):
  • Glucose Urine Present
  • Glycosylated Haemoglobin Increased
  • Proteinuria
The following simultaneously used drugs could have led to this reaction:
  • Voltaren (Unk)
  • Amaryl
The findings here stress that side effects should be taken into consideration when evaluating a Ternelin treatment.

Alanine Aminotransferase Increased, Anorexia, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Hepatic Function Abnormal, Liver Disorder, Lymphocyte Stimulation Test Positive, Malaise
This is a report of a 72-year-old male patient from JAPAN (weight: NA), who used Ternelin (ternelin - Tizanidine Hydrochloride) (dosage: 1 Mg Tid, Oral) for a treatment of myofascial pain syndrome. After starting a treatment on Oct 31, 2007, the patient experienced the following side effect(s):
  • Alanine Aminotransferase Increased
  • Anorexia
  • Aspartate Aminotransferase Increased
  • Blood Alkaline Phosphatase Increased
  • Hepatic Function Abnormal
  • Liver Disorder
  • Lymphocyte Stimulation Test Positive
  • Malaise
The following drugs could possibly have interacted with the Ternelin (ternelin - Tizanidine Hydrochloride) treatment
  • Glysennid
  • Seltouch
The patient was hospitalized.Taken together, these observations suggest that a Ternelin (ternelin - Tizanidine Hydrochloride) treatment could be related to side effect(s), such as Alanine Aminotransferase Increased, Anorexia, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Hepatic Function Abnormal, Liver Disorder, Lymphocyte Stimulation Test Positive, Malaise.

Alanine Aminotransferase Increased, Anorexia, Aspartate Aminotransferase Increased, Bedridden, Blood Lactate Dehydrogenase Increased, Decreased Appetite, Diabetes Mellitus, Diarrhoea
This alanine aminotransferase increased side effect was reported by a physician from JAPAN. A female patient (weight:NA) experienced the following symptoms/conditions: muscle rigidity,pain. The patient was prescribed Ternelin (ternelin - Tizanidine Hydrochloride) 1 Mg (dosage: (df), (1 Mg Tid Oral)), which was started on Dec 05, 2007. Concurrently used drugs: NA. When starting to take Ternelin (ternelin - Tizanidine Hydrochloride) 1 Mg the consumer reported the following symptoms:
  • Alanine Aminotransferase Increased
  • Anorexia
  • Aspartate Aminotransferase Increased
  • Bedridden
  • Blood Lactate Dehydrogenase Increased
  • Decreased Appetite
  • Diabetes Mellitus
  • Diarrhoea
These side effects may potentially be related to Ternelin (ternelin - Tizanidine Hydrochloride) 1 Mg.

Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Decreased Appetite, Diarrhoea, Hepatic Function Abnormal, Nausea, Vomiting
This is a Ternelin side effect report of a 76-year-old female patient (weight:NA) from JAPAN, suffering from the following symptoms/conditions: parkinson's disease, who was treated with Ternelin (dosage:3 Mg/day, start time: Dec 05, 2007), combined with: NA., and developed a serious reaction and a alanine aminotransferase increased side effect. The patient presented with:
  • Alanine Aminotransferase Increased
  • Aspartate Aminotransferase Increased
  • Blood Glucose Increased
  • Blood Lactate Dehydrogenase Increased
  • Decreased Appetite
  • Diarrhoea
  • Hepatic Function Abnormal
  • Nausea
  • Vomiting
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Ternelin treatment in female patients suffering from parkinson's disease, resulting in alanine aminotransferase increased.

Alanine Aminotransferase Increased, Anorexia, Aspartate Aminotransferase Increased, Blood Glucose Increased, Blood Lactate Dehydrogenase Increased, Decreased Appetite, Diarrhoea, Hepatic Function Abnormal, Nausea
This report suggests a potential Ternelin alanine aminotransferase increased side effect(s) that can have serious consequences. A 76-year-old female patient from JAPAN (weight:NA) was diagnosed with the following health condition(s): NA and used Ternelin (dosage: NA) starting Dec 05, 2007. Soon after starting Ternelin the patient began experiencing various side effects, including:
  • Alanine Aminotransferase Increased
  • Anorexia
  • Aspartate Aminotransferase Increased
  • Blood Glucose Increased
  • Blood Lactate Dehydrogenase Increased
  • Decreased Appetite
  • Diarrhoea
  • Hepatic Function Abnormal
  • Nausea
Drugs used concurrently:
  • Voglibose (0.3 Mg, Bid)
  • Ym (9 G, Unk)
  • Choreitou (22.5 Mg, Unk)
  • Forsenid
  • Loxonin
  • Diovan (40 Mg, Qd)
  • Magnesium Oxide (3 G, Unk)
Although Ternelin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as alanine aminotransferase increased, may still occur.

Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Decreased Appetite, Diabetes Mellitus, Hepatic Function Abnormal, Hypertension
This alanine aminotransferase increased problem was reported by a physician from JAPAN. A 76-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Dec 01, 2007 a consumer started treatment with Ternelin (dosage: (df)). The following drugs/medications were being taken at the same time:
  • Voglibose (voglibose) ((0.3 Mg Bid Oral))
  • Diovan (diovan - Valsartan) ( ((df))
  • Ym
  • Choreitou
  • Forsenid /00571901/
When commencing Ternelin, the patient experienced the following unwanted symptoms /side effects:
  • Alanine Aminotransferase Increased
  • Aspartate Aminotransferase Increased
  • Decreased Appetite
  • Diabetes Mellitus
  • Hepatic Function Abnormal
  • Hypertension
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as alanine aminotransferase increased, may become evident only after a product is in use by the general population.

Dysarthria, Spinal Column Stenosis
This is a Ternelin side effect report of a female patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: spinal osteoarthritis and was treated with Ternelin (dosage: (3 Mg Qd Oral)) starting NS. Concurrently used drugs:
  • Lorcam
  • Blopress
  • Trichlormethiazide
  • Natrix
  • Mucosta
  • Meilax
  • Voltaren
Soon after that, the consumer experienced the following of symptoms:
  • Dysarthria
  • Spinal Column Stenosis
The patient was hospitalized. This opens a possibility that Ternelin could cause dysarthria and that some female patients may be more susceptible.

Blood Pressure Systolic Decreased, Depressed Level Of Consciousness, Heart Rate Decreased
A patient (weight: NA) from JAPAN with the following symptoms: accidental exposure started Ternelin (ternelin - Tizanidine Hydrochloride) treatment (dosage: 2 Mg 1x Oral) on Sep 07, 2007. Soon after starting Ternelin (ternelin - Tizanidine Hydrochloride) treatment, the consumer experienced several side effects, including:
  • Blood Pressure Systolic Decreased
  • Depressed Level Of Consciousness
  • Heart Rate Decreased
. Concurrently used drugs:
  • Lasix
  • Aldactone
  • Digoxin
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Ternelin (ternelin - Tizanidine Hydrochloride) side effects, such as blood pressure systolic decreased.

Blood Pressure Systolic Decreased, Heart Rate Decreased
This blood pressure systolic decreased side effect was reported by a physician from JAPAN. A patient (weight:NA) experienced the following symptoms/conditions: accidental exposure.The patient was prescribed Ternelin (ternelin - Tizanidine Hydrochloride) (dosage: 2 Mg 1x Oral), which was started on NS. Concurrently used drugs:
  • Diuretics
.When starting to take Ternelin (ternelin - Tizanidine Hydrochloride) the consumer reported symptoms, such as:
  • Blood Pressure Systolic Decreased
  • Heart Rate Decreased
These side effects may potentially be related to Ternelin (ternelin - Tizanidine Hydrochloride).

Blood Insulin Increased, Diarrhoea, Hyperglycaemia, Hyperhidrosis, Hypoglycaemia, Insulin C-peptide Increased, Pallor, Pneumonia
This is a report of a female patient (weight: NA) from JAPAN, suffering from the following symptoms/conditions: hypertonia, who was treated with Ternelin (ternelin - Tizanidine Hydrochloride) (dosage: 1.5 Mg Qd Oral, start time: Jan 19, 2007), combined with:
  • Dantrium
  • Depakene
  • Lansoprazole
  • Tricloryl
  • Mucodyne
  • Mucosal
  • Klaricid
  • Mya-bm
and developed a serious reaction and side effect(s). The consumer presented with:
  • Blood Insulin Increased
  • Diarrhoea
  • Hyperglycaemia
  • Hyperhidrosis
  • Hypoglycaemia
  • Insulin C-peptide Increased
  • Pallor
  • Pneumonia
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Ternelin (ternelin - Tizanidine Hydrochloride) treatment in female patients, resulting in blood insulin increased side effect. The patient was hospitalized.

Blood Insulin Increased, Diarrhoea, Hyperhidrosis, Hypoglycaemia, Insulin C-peptide Increased, Pallor, Pneumonia
This report suggests a potential Ternelin (ternelin - Tizanidine Hydrochloride) Blood Insulin Increased, Diarrhoea, Hyperhidrosis, Hypoglycaemia, Insulin C-peptide Increased, Pallor, Pneumonia side effect(s) that can have serious consequences. A female patient (weight: NA) from JAPAN was diagnosed with the following symptoms/conditions: hypertonia and used Ternelin (ternelin - Tizanidine Hydrochloride) (dosage: 1.5 Mg Qd Oral) starting Jan 19, 2007. Soon after starting Ternelin (ternelin - Tizanidine Hydrochloride) the patient began experiencing various side effects, including:
  • Blood Insulin Increased
  • Diarrhoea
  • Hyperhidrosis
  • Hypoglycaemia
  • Insulin C-peptide Increased
  • Pallor
  • Pneumonia
Drugs used concurrently:
  • Dantrium
  • Depakene
  • Lansoprazole
  • Tricloryl
  • Mucodyne
  • Mucosal
  • Clarithromycin
  • Miya-bm
The patient was hospitalized. Although Ternelin (ternelin - Tizanidine Hydrochloride) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as blood insulin increased, may still occur.

Cardiac Failure, Cardiac Hypertrophy, Dyspnoea, Malaise, Orthopnoea, Pulmonary Oedema, Weight Increased
This Cardiac Failure, Cardiac Hypertrophy, Dyspnoea, Malaise, Orthopnoea, Pulmonary Oedema, Weight Increased problem was reported by a physician from JAPAN. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: cervicobrachial syndrome. On Apr 04, 2007 this consumer started treatment with Ternelin (ternelin) (acorda Therapeutics) (dosage: (2 Mg Qd Oral)). The following drugs were being taken at the same time: NA. When commencing Ternelin (ternelin) (acorda Therapeutics), the patient experienced the following unwanted symptoms/side effects:
  • Cardiac Failure
  • Cardiac Hypertrophy
  • Dyspnoea
  • Malaise
  • Orthopnoea
  • Pulmonary Oedema
  • Weight Increased
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as cardiac failure, may become evident only after a product is in use by the general population.

Inappropriate Antidiuretic Hormone Secretion
This is a report of a 80-year-old female patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: NA and was treated with Ternelin (ternelin) (dosage: (3 Mg Oral)) starting NS. Concurrently used drugs:
  • Panaldine (panaldine) ((oral))
  • Bayaspirin (bayaspirin) ((oral))
  • Blopress (blopress) (not Specified) ((oral))
  • Amaryl ((oral))
  • Basen (basen) ((oral))
  • Glycoran (glycoran) ((oral))
  • Lendormin (lendormin) (not Specified) ((oral))
  • Dextromethorphan Hydrobromide (medicon) ((oral))
Soon after that, the consumer experienced the following side effects:
  • Inappropriate Antidiuretic Hormone Secretion
This opens a possibility that Ternelin (ternelin) treatment could cause the above reactions, including inappropriate antidiuretic hormone secretion, and some female subjects may be more susceptible.

Cardiac Failure, Cardiac Hypertrophy, Dyspnoea, Haemodialysis, Malaise, Orthopnoea, Weight Increased
A 80-year-old male patient (weight: NA) from JAPAN with the following symptoms/conditions: musculoskeletal stiffness started Ternelin (ternelin) (acorda Therapeutics) treatment (dosage: (3 Mg Qd Oral)) on Mar 29, 2007. Soon after starting Ternelin (ternelin) (acorda Therapeutics) treatment, the subject experienced various side effects, including:
  • Cardiac Failure
  • Cardiac Hypertrophy
  • Dyspnoea
  • Haemodialysis
  • Malaise
  • Orthopnoea
  • Weight Increased
Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some male patients could be more vulnerable to Ternelin (ternelin) (acorda Therapeutics).

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    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
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    Side Effects reported to FDA: 56

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    Reported deaths: 2

    Reported hospitalizations: 20

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