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Thyroxine Side Effects

Common Thyroxine Side Effects

The most commonly reported Thyroxine side effects (click to view or check a box to report):

Cerebral Haemorrhage (5)
Idiopathic Thrombocytopenic Purpura (4)
Carotid Arteriosclerosis (2)
Bradycardia (2)
Diarrhoea (2)
Dyspnoea (2)
Erythema Multiforme (2)
Dizziness (2)
Hyperthyroidism (2)
Leukocytoclastic Vasculitis (2)
Urticaria (2)
Supraventricular Extrasystoles (2)
Thrombocytopenia (2)
Rash (2)
Ocular Hyperaemia (2)
Platelet Count Decreased (2)
Muscular Weakness (1)
Musculoskeletal Pain (1)
Pain In Extremity (1)
Operative Haemorrhage (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Thyroxine Side Effects Reported to FDA

The following Thyroxine reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Thyroxine on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Cellulitis Gangrenous, Pyrexia, Diarrhoea, Vomiting, Abdominal Pain, Chest Pain, Musculoskeletal Pain, Haemodynamic Instability, Dyspnoea
on Jan 28, 2014 Male from GR , 50 years of age, was diagnosed with and was treated with Thyroxine. Directly after, patient experienced the unwanted or unexpected Thyroxine side effects: cellulitis gangrenous, pyrexia, diarrhoea, vomiting, abdominal pain, chest pain, musculoskeletal pain, haemodynamic instability, dyspnoea. Thyroxine dosage: N/A. Patient was hospitalized.

Dizziness, Diarrhoea, Hypertension, Hypotension, Dyspnoea
Patient was taking Thyroxine. Patient felt the following Thyroxine side effects: dizziness, diarrhoea, hypertension, hypotension, dyspnoea on Jan 30, 2014 from US Additional patient health information: Patient , 78 years of age, weighting 131.2 lb, . Thyroxine dosage: N/A.

Exfoliative Rash, Muscular Weakness, Hypocalcaemia, Fatigue
Adverse event was reported on Jan 28, 2014 by a Female taking Thyroxine (Dosage: N/A) was diagnosed with and. Location: GR , 61 years of age, After Thyroxine was administered, patient encountered several Thyroxine side effects: exfoliative rash, muscular weakness, hypocalcaemia, fatigue. Patient was hospitalized.

Fibromyalgia, Irritable Bowel Syndrome, Balance Disorder, Thinking Abnormal, Memory Impairment, Weight Increased, Depression, Product Substitution Issue
on Aug 27, 2013 Female from US , weighting 210.0 lb, was diagnosed with and was treated with Thyroxine. Directly after, patient experienced the unwanted or unexpected Thyroxine side effects: fibromyalgia, irritable bowel syndrome, balance disorder, thinking abnormal, memory impairment, weight increased, depression, product substitution issue. Thyroxine dosage: N/A.
Associated medications used:
  • Vitamin D
  • Estradiol
  • Prometrium
  • Cystone



Sensation Of Heaviness, Gait Disturbance, Pain In Extremity
on Mar 18, 2013 Female from GB , 77 years of age, weighting 125.7 lb, was diagnosed with and was treated with Thyroxine. Patient felt the following Thyroxine side effects: sensation of heaviness, gait disturbance, pain in extremity. Thyroxine dosage: N/A.
Multiple prescriptions taken:
  • Aspirin
  • Simvastatin


Hyperthyroidism, Ocular Hyperaemia, Erythema Multiforme, Supraventricular Extrasystoles, Carotid Arteriosclerosis, Bradycardia
Patient was taking Thyroxine. After Thyroxine was administered, patient encountered several Thyroxine side effects: hyperthyroidism, ocular hyperaemia, erythema multiforme, supraventricular extrasystoles, carotid arteriosclerosis, bradycardia on Oct 09, 2012 from COUNTRY NOT SPECIFIED Additional patient health information: Female , 66 years of age, was diagnosed with and. Thyroxine dosage: N/A. Patient was hospitalized.

Hyperthyroidism, Ocular Hyperaemia, Erythema Multiforme, Supraventricular Extrasystoles, Carotid Arteriosclerosis, Bradycardia
Adverse event was reported on Oct 15, 2012 by a Female taking Thyroxine (Dosage: N/A) was diagnosed with and. Location: COUNTRY NOT SPECIFIED , 66 years of age, Directly after, patient experienced the unwanted or unexpected Thyroxine side effects: hyperthyroidism, ocular hyperaemia, erythema multiforme, supraventricular extrasystoles, carotid arteriosclerosis, bradycardia.
Associated medications used:
  • Clonazepam(clonazepam)
  • Rosuvastatin(rosuvastatin)
  • Cinnarizine(cinnarizine)
  • Telmisartan/amlodipine(tablet) (telmisartan, Amlodipine)
  • Pantoprazole(pantoprazole)
Patient was hospitalized.

Medulloblastoma Recurrent
on Dec 20, 2011 Male from UNITED KINGDOM , child 11 years of age, was treated with Thyroxine (levothyroxine Sodium0. Patient felt the following Thyroxine side effects: medulloblastoma recurrent. Thyroxine (levothyroxine Sodium0 dosage: N/A.
Multiple prescriptions taken:
  • Zomacton (somatropin) Powder And Solvent For Solution For Injection (1 Mg)


Operative Haemorrhage, Serotonin Syndrome, Platelet Count Decreased
on Apr 11, 2011 Female from UNITED KINGDOM , 60 years of age, was treated with Thyroxine. After Thyroxine was administered, patient encountered several Thyroxine side effects: operative haemorrhage, serotonin syndrome, platelet count decreased. Thyroxine dosage: N/A.
Multiple concurrent drugs taken:
  • Fentanyl (2545 Mcg;x1;)
  • Propofol
  • Paroxetine (no Pref. Name)
  • Isoflurane In Oxygen And Air


Cerebral Haemorrhage, Idiopathic Thrombocytopenic Purpura
Patient was taking Thyroxine. Directly after, patient experienced the unwanted or unexpected Thyroxine side effects: cerebral haemorrhage, idiopathic thrombocytopenic purpura on Mar 30, 2011 from Additional patient health information: Male , 64 years of age, weighting 154.3 lb, . Thyroxine dosage: N/A.
Associated medications used:
  • Simvastatin (40mg - Daily - Oral)


Rash, Acne, Urticaria, Pruritus
Adverse event was reported on Apr 15, 2011 by a Female taking Thyroxine (Dosage: N/A) was diagnosed with and. Location: UNITED STATES , weighting 103.6 lb, Patient felt the following Thyroxine side effects: rash, acne, urticaria, pruritus.
Multiple prescriptions taken:
  • Simvastatin
  • Fish Oil
  • Amlodipine Besylate (10 Mg, 1x/day)
  • Calcium


Cerebral Haemorrhage, Idiopathic Thrombocytopenic Purpura, Thrombocytopenia
on Mar 30, 2011 Male from UNITED KINGDOM , 64 years of age, weighting 154.3 lb, was diagnosed with and was treated with Thyroxine. After Thyroxine was administered, patient encountered several Thyroxine side effects: cerebral haemorrhage, idiopathic thrombocytopenic purpura, thrombocytopenia. Thyroxine dosage: 50 Ug, Unk.
Multiple concurrent drugs taken:
  • Simvastatin (40 Mg, Qd)


Blood Bilirubin Increased, Rash, Febrile Neutropenia
on Apr 04, 2011 Female from CANADA , 50 years of age, weighting 116.8 lb, was diagnosed with and was treated with Thyroxine. Directly after, patient experienced the unwanted or unexpected Thyroxine side effects: blood bilirubin increased, rash, febrile neutropenia. Thyroxine dosage: N/A. Patient was hospitalized.

Platelet Count Decreased, Cerebral Haemorrhage
Patient was taking Thyroxine. Patient felt the following Thyroxine side effects: platelet count decreased, cerebral haemorrhage on Feb 24, 2011 from UNITED KINGDOM Additional patient health information: Male , 64 years of age, weighting 154.3 lb, . Thyroxine dosage: N/A.
Multiple prescriptions taken:
  • Simvastatin (40 Mg, Daily, Oral)


Lymphocytosis
Adverse event was reported on Mar 08, 2011 by a Female taking Thyroxine (Dosage: 100 Ug, 1x/day) was diagnosed with and. Location: UNITED KINGDOM , 68 years of age, weighting 121.3 lb, After Thyroxine was administered, patient encountered several Thyroxine side effects: lymphocytosis.
Multiple concurrent drugs taken:
  • Meloxicam (7.5 Mg, 1x/day)
  • Enbrel (50 Mg, Weekly)
  • Prednisolone (7.5 Mg, 1x/day)


Cerebral Haemorrhage, Idiopathic Thrombocytopenic Purpura, Thrombocytopenia
on Feb 24, 2011 Male from UNITED KINGDOM , 64 years of age, weighting 154.3 lb, was diagnosed with and was treated with Thyroxine. Directly after, patient experienced the unwanted or unexpected Thyroxine side effects: cerebral haemorrhage, idiopathic thrombocytopenic purpura, thrombocytopenia. Thyroxine dosage: N/A.
Associated medications used:
  • Simvastatin (40 Mg, Daily)


Cerebral Haemorrhage, Idiopathic Thrombocytopenic Purpura
on Feb 01, 2011 Male from , 64 years of age, weighting 154.3 lb, was treated with Thyroxine. Patient felt the following Thyroxine side effects: cerebral haemorrhage, idiopathic thrombocytopenic purpura. Thyroxine dosage: N/A.
Multiple prescriptions taken:
  • Simvastatin (40mg - Daily - Oral)


Swelling Face, Urticaria
Patient was taking Thyroxine. After Thyroxine was administered, patient encountered several Thyroxine side effects: swelling face, urticaria on Jan 03, 2006 from UNITED KINGDOM Additional patient health information: Patient , 69 years of age, . Thyroxine dosage: N/A.
Multiple concurrent drugs taken:
  • Aspirin
  • Lisinopril
  • Bendrofluazide
  • Ferrous Sulfate Tab
  • Diclofenac (75mg Daily)


Leukocytoclastic Vasculitis
Adverse event was reported on Oct 05, 2005 by a Female taking Thyroxine (Dosage: Daily Dose: 100 Microgram(s)) was diagnosed with and. Location: AUSTRALIA , weighting 154.3 lb, Directly after, patient experienced the unwanted or unexpected Thyroxine side effects: leukocytoclastic vasculitis.
Associated medications used:
  • Luvox (Daily Dose: 50 Milligram(s))


Leukocytoclastic Vasculitis
on Oct 05, 2005 Female from AUSTRALIA , weighting 154.3 lb, was diagnosed with and was treated with Thyroxine. Patient felt the following Thyroxine side effects: leukocytoclastic vasculitis. Thyroxine dosage: N/A.
Multiple prescriptions taken:
  • Luvox (Daily Dose: 50 Milligram(s))




Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:

     

    Side Effects

    Scale

    Date & Time

    Other Medicine(s) or Treatment(s)

     

     

     

     

    Scale: 1 = very mild to 10 = very bad


    Track Online

  • User Sign In
  • Register to track your side effects

  • You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Discuss Thyroxine Side Effects



    Did You Have a Thyroxine Side Effect?

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    Yes, Moderate
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    How Effective is Thyroxine for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
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    Safety Alerts, Active Ingredients, Usage Information

    Alternative THYROXINE Names:LEVOTHYRO

    Active Ingredient: LEVOTHYRO

    More About Thyroxine

    Side Effects reported to FDA: 20

    Thyroxine safety alerts: 2004

    Reported deaths: 5

    Reported hospitalizations: 5

    Levoxyl (levothyroxine sodium)

    Audience: Endocrinologists and other healthcare professionals

    FDA and King Pharmaceuticals notified healthcare professionals of revisions to the PRECAUTIONS, ADVERSE REACTIONS and DOSAGE AND ADMINISTRATION sections of labeling, describing reports of choking, gagging, tablets stuck in throat and dysphagia while taking Levoxyl. These reports have predominately occurred when Levoxyl tablets were not taken with water. It is recommended that Levoxyl tablets be taken with a full glass of water.

    [September 17, 2004 - Letter - King Pharmaceuticals]

    Latest Thyroxine clinical trials