Tikosyn Side Effects
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Tikosyn Safety Reports reported to FDA
Total Tikosyn reports: 121.Tikosyn FDA safety alerts: No.
Reported deaths: 2 Reported hospitalizations: 26.
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Reported Tikosyn Side Effects: atrial fibrillation, dizziness, fatigue, heart rate increased, asthenia, chest pain, condition aggravated, vision blurred, arrhythmia, nausea, dyspnoea.
Tikosyn Usage.
If you have questions about Tikosyn, you can ask a Health Expert or Ask Patient Community about Tikosyn.
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Tikosyn Side Effects Report #5403206-8Health Professional from UNITED STATES reported TIKOSYN problem on July 20, 2007. Male patient, weighting 274.9 lb, was diagnosed with arrhythmia, back pain and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: vision blurred. TIKOSYN dosage: unknown. During the same period patient was treated with IMDUR, TOPROL, COUMADIN, ZETIA, ULTRAM, LIPITOR, DIOVAN, ASPIRIN. Patient recovered.
Tikosyn Side Effects Report #5404347-1
TIKOSYN problem was reported by a Physician from UNITED STATES on July 21, 2007. Female patient, weighting 200.0 lb, was diagnosed with arrhythmia, pneumonia and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: arrhythmia. TIKOSYN dosage: unknown. During the same period patient was treated with AVELOX, ALLOPURINOL, NEORAL, NEXIUM, LASIX, POTASSIUM CHLORIDE, PREDNISONE, CUMADIN. Patient recovered.
Tikosyn Side Effects Report #5406599-0
Consumer or non-health professional from UNITED STATES reported TIKOSYN problem on July 25, 2007. Female patient, weighting 238.5 lb, was diagnosed with atrial fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: dyspnoea, fracture, heart rate decreased, type 2 diabetes mellitus, upper limb fracture. TIKOSYN dosage: unknown. During the same period patient was treated with ADVAIR DISKUS, ACTOS, AVAPRO, FERROUS SULPHATE, ICAPS, MELOXICAM, PREDNISONE, PREVACID. Patient recovered.
Tikosyn Side Effects Report #5407581-X
TIKOSYN problem was reported by a Consumer or non-health professional from UNITED STATES on July 26, 2007. Female patient, weighting 168.0 lb, was diagnosed with atrial fibrillation, hypertension and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: back pain, blood calcium decreased, blood pressure fluctuation, heart rate increased, herpes zoster, infection, nerve compression. TIKOSYN dosage: unknown. During the same period patient was treated with HYDROCHLOROTHIAZIDE, ATENOLOL, WARFARIN, PREVACID, ZESTRIL, PRAVACHOL, MIACALCIN. Patient recovered.
Tikosyn Side Effects Report #5408634-2
Pharmacist from UNITED STATES reported TIKOSYN problem on July 27, 2007. Male patient, weighting 163.1 lb, was diagnosed with atrial fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, liver function test abnormal, lymphadenopathy mediastinal. TIKOSYN dosage: unknown. During the same period patient was treated with COLACE, TEMAZEPAM, TYLENOL, VALSARTAN, ASCORBIC ACID, VITAMINS WITH MINERALS. Patient recovered.
Tikosyn Side Effects Report #5411548-5
TIKOSYN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 01, 2007. Male patient, weighting 225.5 lb, was diagnosed with atrial fibrillation, hypertension, cardiac failure congestive and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, erectile dysfunction. TIKOSYN dosage: unknown. During the same period patient was treated with COREG, TERAZOSIN, ENALAPRIL MALEATE, CARDIZEM, FUROSEMIDE, MONTELUKAST, CUMADIN. Patient recovered.
Tikosyn Side Effects Report #5411575-8
Physician from UNITED STATES reported TIKOSYN problem on July 31, 2007. Male patient, weighting 274.9 lb, was diagnosed with arrhythmia, back pain and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: vision blurred. TIKOSYN dosage: unknown. During the same period patient was treated with IMDUR, TOPROL, COUMADIN, ZETIA, ULTRAM, LIPITOR, DIOVAN, ASPIRIN. Patient recovered.
Tikosyn Side Effects Report #5412986-7
TIKOSYN problem was reported by a Physician from UNITED STATES on Aug 03, 2007. Female patient, 72 years of age, weighting 190.0 lb, was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: fluid retention. TIKOSYN dosage: unknown. During the same period patient was treated with NITROGLYCERIN, TYLENOL, ASCORBIC ACID, ACETYLSALICYLIC ACID SRT, ATENOLOL, CALCIUM CARBONATE, CHOLESTYRAMINE, VITAMIN B. Patient recovered.
Tikosyn Side Effects Report #5419887-9
Physician from UNITED STATES reported TIKOSYN problem on Aug 08, 2007. Female patient, weighting 200.0 lb, was diagnosed with arrhythmia, pneumonia and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: arrhythmia. TIKOSYN dosage: unknown. During the same period patient was treated with AVELOX, ALLOPURINOL, NEORAL, NEXIUM, LASIX, POTASSIUM CHLORIDE, PREDNISONE, CUMADIN. Patient recovered.
Tikosyn Side Effects Report #5421635-3
TIKOSYN problem was reported by a Health Professional from UNITED STATES on Aug 09, 2007. Male patient, weighting 162.0 lb, was diagnosed with atrial fibrillation, type 2 diabetes mellitus and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal pain, depression, diabetes mellitus, dizziness, fatigue, hot flush, left ventricular failure. TIKOSYN dosage: unknown. During the same period patient was treated with JANUVIA, ZETIA, COUMADIN, ASPIRIN, OMEPRAZOLE, POTASSIUM CHLORIDE, ISOSORBIDE MONONITRATE, BUMEX. Patient recovered.
Tikosyn Side Effects Report #5422287-9
Consumer or non-health professional from UNITED STATES reported TIKOSYN problem on Aug 20, 2007. Female patient, 43 years of age, weighting 201.5 lb, was diagnosed with atrial fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: hypokalaemia, renal impairment, ventricular fibrillation. TIKOSYN dosage: unknown. Patient was hospitalized. Patient recovered.
Tikosyn Side Effects Report #5425436-1
TIKOSYN problem was reported by a Physician from UNITED STATES on Aug 15, 2007. Male patient, weighting 165.3 lb, was diagnosed with atrial fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: fall, renal failure acute. TIKOSYN dosage: unknown. During the same period patient was treated with COREG, LASIX, TYLENOL, NEXIUM, GLUCOTROL, PRINIVIL, VENTOLIN, VICODIN. Patient was hospitalized. Patient recovered.
Tikosyn Side Effects Report #5429852-3
Consumer or non-health professional from UNITED STATES reported TIKOSYN problem on Aug 20, 2007. Female patient, weighting 145.3 lb, was diagnosed with arrhythmia, cardiac fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: staphylococcal infection. TIKOSYN dosage: unknown. Patient recovered.
Tikosyn Side Effects Report #5430062-4
TIKOSYN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 20, 2007. Female patient, weighting 145.3 lb, was diagnosed with arrhythmia, cardiac fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: breast cancer. TIKOSYN dosage: unknown. Patient recovered.
Tikosyn Side Effects Report #5444161-4
Health Professional from UNITED STATES reported TIKOSYN problem on Sept 04, 2007. Male patient, weighting 196.0 lb, was diagnosed with atrial fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: disease recurrence, pneumonia. TIKOSYN dosage: unknown. Patient recovered.
Tikosyn Side Effects Report #5453088-3
TIKOSYN problem was reported by a Consumer or non-health professional from CANADA on Sept 05, 2007. Male patient, 40 years of age, weighting 178.6 lb, was diagnosed with ventricular tachycardia, ventricular dysfunction, blood cholesterol abnormal and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood lactate dehydrogenase increased, blood pressure decreased, hepatic enzyme increased. TIKOSYN dosage: unknown. During the same period patient was treated with AMIODARONE, MONOCOR, CELLCEPT, CRESTOR, ZESTRIL, LASIX, LOSEC I, COUMADIN. Patient recovered.
Tikosyn Side Effects Report #5454487-6
Physician from UNITED STATES reported TIKOSYN problem on Sept 05, 2007. Female patient, 50 years of age, was diagnosed with atrial fibrillation and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: headache, hyponatraemia, nausea. TIKOSYN dosage: unknown. Patient was hospitalized. Patient recovered.
Tikosyn Side Effects Report #5460591-9
TIKOSYN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 09, 2007. Female patient, weighting 125.0 lb, was diagnosed with tachycardia and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: cardiac ablation, dizziness, nausea. TIKOSYN dosage: unknown. During the same period patient was treated with COUMADIN, DIGITEK, FLOLAN. Patient recovered.
Tikosyn Side Effects Report #5464678-6
Physician from UNITED STATES reported TIKOSYN problem on Sept 12, 2007. Female patient, weighting 200.0 lb, was diagnosed with arrhythmia, pneumonia and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: arrhythmia. TIKOSYN dosage: unknown. During the same period patient was treated with AVELOX, ALLOPURINOL, NEORAL, NEXIUM, LASIX, POTASSIUM CHLORIDE, PREDNISONE, CUMADIN. Patient recovered.
Tikosyn Side Effects Report #5464741-X
TIKOSYN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 10, 2007. Male patient, weighting 210.4 lb, was diagnosed with atrial fibrillation, hypertension and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: chest pain, diarrhoea, flushing, liver scan abnormal, renal impairment. TIKOSYN dosage: unknown. During the same period patient was treated with WELCHOL, PRILOSEC, ATACAND, PLAVIX, ATIVAN, ATENOLOL, POTASSIUM CHLORIDE. Patient recovered.
Tikosyn Side Effects Report #5470079-7
Consumer or non-health professional from UNITED STATES reported TIKOSYN problem on Sept 18, 2007. Male patient, weighting 210.4 lb, was diagnosed with atrial fibrillation, hypertension and was treated with TIKOSYN. After drug was administered, patient experienced the following problems/side effects: chest pain, diarrhoea, flushing, liver scan abnormal, renal impairment. TIKOSYN dosage: unknown. During the same period patient was treated with WELCHOL, PRILOSEC, ATACAND, PLAVIX, ATIVAN, ATENOLOL, POTASSIUM CHLORIDE. Patient recovered.
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Drug Information: Dofetilide
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601235.html
(doe fet' il ide)IMPORTANT WARNING:
| Tikosyn can cause your heart to beat irregularly. You will need to be in a hospital or another place where you can be monitored closely by your doctor for at least 3 days when you are started or restarted on dofetilide. It is important to read the patient information provided to you every time you begin therapy with dofetilide. |
Why is this medication prescribed?
Dofetilide is used to treat irregular heartbeats. It improves your heart rhythm by relaxing an overactive heart.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?
Dofetilide comes as a capsule to take by mouth. It is usually taken twice a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dofetilide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Do not take a double dose.
Dofetilide controls abnormal heart rhythms but does not cure them. Continue to take dofetilide even if you feel well. Do not stop taking dofetilide without talking to your doctor.
What special precautions should I follow?
Before taking dofetilide,
- tell your doctor and pharmacist if you are allergic to dofetilide or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antipsychotics, bepridil (Vascor), cimetidine (Tagamet), cisapride (Propulsid), clarithromycin (Biaxin), diltiazem (Cardizem), diuretics ('water pills'), erythromycin (E.E.S., E-Mycin, others), HIV protease inhibitors such as ritonavir (Norvir), itraconazole (Sporanox), ketoconazole (Nizoral), medications for dizziness or nausea, medications for depression such as amitriptyline (Elavil) or fluoxetine (Prozac), megestrol (Megace), metformin (Glucophage), other medications for irregular heart beats such as amiodarone (Cordarone), norfloxacin (Noroxin), prochlorperazine (Compazine), quinine (Formula Q), trimethoprim (Proloprim, Trimpex), trimethoprim and sulfamethoxazole (Bactrim, Septra), verapamil (Calan, Covera, Verelan), zafirlukast (Accolate), and vitamins.
- tell your doctor if you have or have ever had long QT syndrome (a type of heart problem), or kidney or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking dofetilide, call your doctor.
What special dietary instructions should I follow?
Talk to your doctor before drinking grapefruit juice. It may be best to drink other fruit juices while taking dofetilide.
What should I do if I forget a dose?
Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Dofetilide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache
- chest pain
- dizziness
- respiratory infection
- flu-like symptoms
- stomach pain
- back pain
- diarrhea
- difficulty sleeping
If you experience any of the following symptoms, call your doctor immediately:
- irregular heartbeat
- rash
- sweating
- upset stomach
- vomiting
- loss of appetite or thirst
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your heart rhythm should be checked regularly to determine your response to dofetilide. Your doctor will also want to follow your kidney function and blood level of potassium closely while you are taking dofetilide.
If you are ill for more than 24 hours with diarrhea, vomiting, or sweating and have not been able to take in much fluid or nutrition you should call your doctor before taking your next dose of dofetilide.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Brand name(s):
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