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Topiramate Side Effects

PatientsVille

Common Topiramate Side Effects


The most commonly reported Topiramate side effects (click to view or check a box to report):

Product Substitution Issue (210)
Convulsion (207)
Headache (120)
Angle Closure Glaucoma (96)
Confusional State (87)
Dizziness (79)
Somnolence (78)
Vision Blurred (74)
Migraine (73)
Paraesthesia (72)
Toxicity To Various Agents (71)
Metabolic Acidosis (70)
Myopia (67)
Weight Decreased (65)
Fatigue (65)
Nausea (62)
Condition Aggravated (61)
Depression (59)
Memory Impairment (58)
Completed Suicide (53)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Topiramate Side Effects Reported to FDA



Topiramate Side Effect Report#9999221
Cognitive Disorder, Depression, Suicidal Ideation
This is a report of a 49-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Topiramate (dosage: 2 Pills Twice Daily, start time:
Feb 04, 2014), combined with: NA. and developed a serious reaction and side effect(s): Cognitive Disorder, Depression, Suicidal Ideation after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Topiramate treatment in female patients, resulting in Cognitive Disorder side effect.
Topiramate Side Effect Report#9999170
Priapism, Off Label Use
This report suggests a potential Topiramate Priapism side effect(s) that can have serious consequences. A 22-year-old male patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: autism and used Topiramate (dosage: NA) starting NS. After starting Topiramate the patient began experiencing various side effects, including: Priapism, Off Label UseAdditional drugs used concurrently:
  • Olanzapine
Although Topiramate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Priapism, may still occur.
Topiramate Side Effect Report#9999149
Granuloma Annulare, Skin Hyperpigmentation, Weight Decreased
This Granuloma Annulare problem was reported by a physician from IT. A 50-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: headache,weight increased. On 201001 this consumer started treatment with Topiramate (dosage: NA). The following drugs were being taken at the same time: NA. When using Topiramate, the patient experienced the following unwanted symptoms/side effects: Granuloma Annulare, Skin Hyperpigmentation, Weight DecreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Granuloma Annulare, may become evident only after a product is in use by the general population.
Topiramate Side Effect Report#9999089
Granuloma Annulare, Skin Hyperpigmentation, Weight Decreased
This Granuloma Annulare side effect was reported by a health professional from IT. A 50-year-old female patient (weight:NA) experienced the following symptoms/conditions: headache,weight increased.The patient was prescribed Topiramate (drug dosage: NA), which was initiated on 201001. Concurrently used drugs: NA..After starting to take Topiramate the consumer reported adverse symptoms, such as: Granuloma Annulare, Skin Hyperpigmentation, Weight DecreasedThese side effects may potentially be related to Topiramate.
Topiramate Side Effect Report#9998980
Lethargy, Fatigue, Euphoric Mood, Feeling Abnormal
This is a report of a 15-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: migraine, who was treated with Topiramate (dosage: NA, start time:
Feb 12, 2014), combined with: NA. and developed a serious reaction and side effect(s): Lethargy, Fatigue, Euphoric Mood, Feeling Abnormal after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Topiramate treatment in female patients, resulting in Lethargy side effect.
Topiramate Side Effect Report#9980309
Feeling Abnormal, Glaucoma, Visual Acuity Reduced
This report suggests a potential Topiramate 25mg Glenmark Pharmaceuticals Feeling Abnormal side effect(s) that can have serious consequences. A 34-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: migraine prophylaxis and used Topiramate 25mg Glenmark Pharmaceuticals (dosage: 1 Bid Oral) starting
Feb 17, 2014. After starting Topiramate 25mg Glenmark Pharmaceuticals the patient began experiencing various side effects, including: Feeling Abnormal, Glaucoma, Visual Acuity ReducedAdditional drugs used concurrently:
  • Sumatriptan
Although Topiramate 25mg Glenmark Pharmaceuticals demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Feeling Abnormal, may still occur.
Topiramate Side Effect Report#9936752
Angle Closure Glaucoma
This Angle Closure Glaucoma problem was reported by a physician from IN. A 28-year-old patient (weight: NA) was diagnosed with the following symptoms/conditions: headache. On NS this consumer started treatment with Topiramate (dosage: NA). The following drugs were being taken at the same time: NA. When using Topiramate, the patient experienced the following unwanted symptoms/side effects: Angle Closure GlaucomaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Angle Closure Glaucoma, may become evident only after a product is in use by the general population.
Topiramate Side Effect Report#9936751
Choroidal Detachment, Iridocyclitis
This Choroidal Detachment side effect was reported by a physician from IN. A 38-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Topiramate (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Topiramate the consumer reported adverse symptoms, such as: Choroidal Detachment, IridocyclitisThese side effects may potentially be related to Topiramate.
Topiramate Side Effect Report#9924781
Visual Impairment, Hallucination, Chromatopsia, Vision Blurred, Tinnitus
This is a report of a 33-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: migraine, who was treated with Topiramate (dosage: 3 Pills Once Daily Taken By Mouth, start time:
Jan 01, 2014), combined with: NA. and developed a serious reaction and side effect(s): Visual Impairment, Hallucination, Chromatopsia, Vision Blurred, Tinnitus after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Topiramate treatment in female patients, resulting in Visual Impairment side effect.
Topiramate Side Effect Report#9924345
Mania, Suicidal Ideation, Homicidal Ideation
This report suggests a potential Topiramate Mania side effect(s) that can have serious consequences. A 57-year-old female patient (weight: NA) from DE was diagnosed with the following symptoms/conditions: epilepsy and used Topiramate (dosage: 200 Mg/day) starting NS. After starting Topiramate the patient began experiencing various side effects, including: Mania, Suicidal Ideation, Homicidal IdeationAdditional drugs used concurrently:
  • Tiagabine (40 Mg/day)
The patient was hospitalized. Although Topiramate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Mania, may still occur.
Topiramate Side Effect Report#9915663
Sudden Visual Loss, Eye Pain, Vomiting, Corneal Oedema
This Sudden Visual Loss problem was reported by a consumer or non-health professional from US. A 59-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: weight control. On
Nov 11, 2013 this consumer started treatment with Topiramate (dosage: 2mg 1 Pill Qam Oral). The following drugs were being taken at the same time:
  • Losartan
  • Advair
  • Zyrtec
  • Synthroid
  • Omeprazole
When using Topiramate, the patient experienced the following unwanted symptoms/side effects: Sudden Visual Loss, Eye Pain, Vomiting, Corneal OedemaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Sudden Visual Loss, may become evident only after a product is in use by the general population.
Topiramate Side Effect Report#9914956
Granuloma Annulare, Skin Mass, Skin Lesion, Post Inflammatory Pigmentation Change, Weight Decreased
This Granuloma Annulare side effect was reported by a health professional from IT. A 50-year-old female patient (weight:NA) experienced the following symptoms/conditions: headache.The patient was prescribed Topiramate (drug dosage: 50 Mg, Unk), which was initiated on 201001. Concurrently used drugs: NA..After starting to take Topiramate the consumer reported adverse symptoms, such as: Granuloma Annulare, Skin Mass, Skin Lesion, Post Inflammatory Pigmentation Change, Weight DecreasedThese side effects may potentially be related to Topiramate.
Topiramate Side Effect Report#9914221
Completed Suicide, Exposure Via Ingestion, Toxicity To Various Agents
This is a report of a 51-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Topiramate (dosage: NA, start time: NS), combined with:
  • Gabapentin (gabapentin)
  • Diltiazem
  • Metoprolol (metoprolol)
  • Bupropion (bupropion)
  • Tramadol (tramadol)
  • Oxcarbazepine (oxcarbazepine)
  • Trazodone (trazodone)
  • Diphenhydramine (diphenhydramine)
and developed a serious reaction and side effect(s): Completed Suicide, Exposure Via Ingestion, Toxicity To Various Agents after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Topiramate treatment in female patients, resulting in Completed Suicide side effect.
Topiramate Side Effect Report#9914167
Toxicity To Various Agents
This report suggests a potential Topiramate (topiramate) Toxicity To Various Agents side effect(s) that can have serious consequences. A 51-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Topiramate (topiramate) (dosage: NA) starting NS. After starting Topiramate (topiramate) the patient began experiencing various side effects, including: Toxicity To Various AgentsAdditional drugs used concurrently:
  • Oxycodone (oxycodone)
  • Morphine
  • Amitriptyline (amitriptyline)
  • Tramadol (tramadol)
  • Diphenhydramine (diphenhydramine)
Although Topiramate (topiramate) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Toxicity To Various Agents, may still occur.
Topiramate Side Effect Report#9913991
Paraesthesia, Abdominal Distension, Thirst, Gingival Bleeding, Tooth Socket Haemorrhage, Dry Eye, Vomiting, Throat Irritation, Lacrimation Increased
This Paraesthesia problem was reported by a consumer or non-health professional from US. A 18-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Topiramate 100mg Zydus (dosage: 2 Pills Twice Daily Taken By Mouth). The following drugs were being taken at the same time: NA. When using Topiramate 100mg Zydus, the patient experienced the following unwanted symptoms/side effects: Paraesthesia, Abdominal Distension, Thirst, Gingival Bleeding, Tooth Socket Haemorrhage, Dry Eye, Vomiting, Throat Irritation, Lacrimation IncreasedThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Paraesthesia, may become evident only after a product is in use by the general population.
Topiramate Side Effect Report#9913890
Toxicity To Various Agents
This Toxicity To Various Agents side effect was reported by a pharmacist from US. A 34-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Topiramate (topiramate) (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Mirtazapine (mirtazapine)
  • Methadone (methadone)
  • Heroin (diamorphine) (diamorphine)
  • Promethazine (promethazine)
  • Diphenhydramine (diphenhydramine)
.After starting to take Topiramate (topiramate) the consumer reported adverse symptoms, such as: Toxicity To Various AgentsThese side effects may potentially be related to Topiramate (topiramate).
Topiramate Side Effect Report#9913884
Exposure Via Ingestion, Toxicity To Various Agents, Cardiac Arrest, Respiratory Arrest
This is a report of a 34-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Topiramate (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Exposure Via Ingestion, Toxicity To Various Agents, Cardiac Arrest, Respiratory Arrest after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Topiramate treatment in female patients, resulting in Exposure Via Ingestion side effect.
Topiramate Side Effect Report#9911760
Conjunctival Hyperaemia, Conjunctival Oedema, Myopia
This report suggests a potential Topiramate Conjunctival Hyperaemia side effect(s) that can have serious consequences. A 34-year-old female patient (weight: NA) from PT was diagnosed with the following symptoms/conditions: prophylaxis and used Topiramate (dosage: 75 Mg, Unk) starting
Aug 10, 2010. After starting Topiramate the patient began experiencing various side effects, including: Conjunctival Hyperaemia, Conjunctival Oedema, MyopiaAdditional drugs used concurrently: NA. Although Topiramate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Conjunctival Hyperaemia, may still occur.
Topiramate Side Effect Report#9910068
Myopia, Retinal Tear, Angle Closure Glaucoma
This Myopia problem was reported by a consumer or non-health professional from US. A 29-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: migraine. On
Jan 22, 2014 this consumer started treatment with Topiramate (dosage: NA). The following drugs were being taken at the same time: NA. When using Topiramate, the patient experienced the following unwanted symptoms/side effects: Myopia, Retinal Tear, Angle Closure GlaucomaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Myopia, may become evident only after a product is in use by the general population.
Topiramate Side Effect Report#9909639
Cardio-respiratory Arrest, Completed Suicide, Exposure Via Ingestion
This Cardio-respiratory Arrest side effect was reported by a pharmacist from US. A 30-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Topiramate (topiramate) (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Lacosamide
  • Pregabalin (pregabalin)
  • Phenytoin (phenytoin)
  • Folic Acid (folic Acid)
  • Azithromycin (azithromycin)
.After starting to take Topiramate (topiramate) the consumer reported adverse symptoms, such as: Cardio-respiratory Arrest, Completed Suicide, Exposure Via IngestionThese side effects may potentially be related to Topiramate (topiramate).
Topiramate Side Effect Report#9908695
Toxicity To Various Agents
This is a report of a 41-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Topiramate (topiramate) (dosage: NA, start time: NS), combined with:
  • Heroin (diamorphine) (diamorphine)
  • Cocaine (cocaine)
  • Diltiazem (diltiazem) (diltiazem)
  • Quinine
and developed a serious reaction and side effect(s): Toxicity To Various Agents after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Topiramate (topiramate) treatment in male patients, resulting in Toxicity To Various Agents side effect.
Topiramate Side Effect Report#9908423
Respiratory Arrest, Cardiac Arrest, Exposure Via Ingestion, Toxicity To Various Agents
This report suggests a potential Topiramate (topiramate) Respiratory Arrest side effect(s) that can have serious consequences. A 40-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Topiramate (topiramate) (dosage: NA) starting NS. After starting Topiramate (topiramate) the patient began experiencing various side effects, including: Respiratory Arrest, Cardiac Arrest, Exposure Via Ingestion, Toxicity To Various AgentsAdditional drugs used concurrently: NA. Although Topiramate (topiramate) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Respiratory Arrest, may still occur.
Topiramate Side Effect Report#9905868
Toxicity To Various Agents, Exposure Via Ingestion
This Toxicity To Various Agents problem was reported by a pharmacist from US. A 44-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Topiramate (topiramate) (dosage: NA). The following drugs were being taken at the same time:
  • Olanzapine (olanzapine)
  • Heroin (diamorphine) (diamorphine) (Parenteral)
  • Methadone (methadone)
  • Cocaine (cocaine)
  • Dextromethorphan (dextromethorphan)
  • Diltiazem
  • Codeine (codeine)
When using Topiramate (topiramate), the patient experienced the following unwanted symptoms/side effects: Toxicity To Various Agents, Exposure Via IngestionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Toxicity To Various Agents, may become evident only after a product is in use by the general population.
Topiramate Side Effect Report#9904827
Paraesthesia, Product Substitution Issue
This Paraesthesia side effect was reported by a consumer or non-health professional from US. A 46-year-old female patient (weight:NA) experienced the following symptoms/conditions: migraine.The patient was prescribed Topiramate (drug dosage: One Tablet Twice Daily Taken By Mouth), which was initiated on
Apr 30, 2012. Concurrently used drugs: NA..After starting to take Topiramate the consumer reported adverse symptoms, such as: Paraesthesia, Product Substitution IssueThese side effects may potentially be related to Topiramate.
Topiramate Side Effect Report#9897465
Status Epilepticus, Off Label Use
This is a report of a 79-year-old male patient (weight: NA) from DE, suffering from the following health symptoms/conditions: status epilepticus, who was treated with Topiramate (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Status Epilepticus, Off Label Use after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Topiramate treatment in male patients, resulting in Status Epilepticus side effect.


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The appearance of Topiramate on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Topiramate Side Effects for Women?

Women Side EffectsReports
Product Substitution Issue 171
Convulsion 137
Headache 89
Angle Closure Glaucoma 71
Migraine 63
Confusional State 62
Paraesthesia 61
Vision Blurred 55
Dizziness 54
Depression 53

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Topiramate reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Topiramate Side Effects

    Did You Have a Topiramate Side Effect?

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    How Effective is Topiramate for You?

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    Topiramate Safety Alerts, Active Ingredients, Usage Information

    NDC0093-0155
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameTopiramate
    NameTopiramate
    Dosage FormTABLET
    RouteORAL
    On market since20090331
    LabelerTeva Pharmaceuticals USA Inc
    Active Ingredient(s)TOPIRAMATE
    Strength(s)25
    Unit(s)mg/1
    Pharma ClassAnti-epileptic Agent [EPC],Decreased Central Nervous System Disorganized Electrical Activity [PE]

    Topiramate Dosage, Warnings, Usage.

    Side Effects reported to FDA: 2115

    Topiramate safety alerts: 2011 2005 2003 2001

    Reported deaths: 191

    Reported hospitalizations: 589

    Topamax (topiramate): Recall - Musty Odor

    [Posted 04/15/2011]

    AUDIENCE: Risk Manager, Pharmacy, Patients

    ISSUE: Ortho-McNeil Neurologics Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., is recalling two lots of Topamax (topiramate) 100mg Tablets. The recall stems from four consumer reports of an uncharacteristic odor thought to be caused by trace amounts of TBA (2,4,6 tribromoanisole). While not considered to be toxic, TBA can generate an offensive odor and a small number of patients have reported temporary gastrointestinal symptoms. There have been no reported serious adverse events caused by the presence of TBA in Topamax.

    BACKGROUND: Topamax is indicated as initial monotherapy in patients 10 years of age and older with partial onset or primary generalized tonic-clonic seizures; as adjunctive therapy for adults and pediatric patients ages 2 − 16 years with partial onset seizures, or primary generalized tonic-clonic seizures, and in patients 2 years of age and older with seizures associated with Lennox-Gastaut syndrome; and for adults for the prophylaxis of migraine headache.

    RECOMMENDATION: Patients taking Topamax 100mg Tablets who experience an uncharacteristic odor associated with their medication should return the tablets to their pharmacist, and contact their healthcare professional if they have questions.

    Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:

    • Complete and submit the report Online: www.fda.gov/MedWatch/report.htm
    • Download form or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178

     

    [04/14/2011 - Press Release - Ortho-McNeil]

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