Topotecan Side Effects
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Topotecan Safety Reports reported to FDA
Total Topotecan reports: 138.Topotecan FDA safety alerts: No.
Reported deaths: 17 Reported hospitalizations: 121.
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Reported Topotecan Side Effects: dehydration, anaemia, dyspnoea, vomiting, nausea, pyrexia, fatigue, neutropenia, thrombocytopenia, pancytopenia, confusional state.
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Topotecan Side Effects Report #5196578-3Health Professional from UNITED STATES reported TOPOTECAN problem on Dec 28, 2006. Female patient, weighting 146.0 lb, was diagnosed with small cell carcinoma, vaginal cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, vomiting. TOPOTECAN dosage: 3MG/M2 D 1,8,15 Q28 IV. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5376096-X
TOPOTECAN problem was reported by a Physician from HUNGARY on June 22, 2007. Female patient, 64 years of age, weighting 174.2 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, fatigue, leukopenia, neutropenia, pancytopenia, pyrexia, syncope, thrombocytopenia. TOPOTECAN dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5380752-7
Physician from HUNGARY reported TOPOTECAN problem on July 04, 2007. Female patient, 64 years of age, weighting 174.2 lb, was diagnosed with metastases to central nervous system and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, bedridden, fatigue, heart rate increased, impaired self-care, leukopenia, neutropenia, pancytopenia. TOPOTECAN dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5381970-4
TOPOTECAN problem was reported by a Physician from UNITED STATES on July 05, 2007. Female patient, 70 years of age, was diagnosed with depression, nausea, pain and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, urinary tract infection, vomiting. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, CELEXA, CARDIZEM, MS CONTIN, PHENERGAN, DILAUDID. Patient recovered.
Topotecan Side Effects Report #5384177-X
Physician from HUNGARY reported TOPOTECAN problem on July 06, 2007. Female patient, 64 years of age, weighting 174.2 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, bedridden, fatigue, impaired self-care, leukopenia, neutropenia, pancytopenia, pyrexia. TOPOTECAN dosage: 4MG PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5386556-3
TOPOTECAN problem was reported by a Physician from UNITED STATES on July 09, 2007. Female patient, 70 years of age, was diagnosed with depression, nausea, pain and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, urinary tract infection, vomiting. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, CELEXA, CARDIZEM, MS CONTIN, PHENERGAN, DILAUDID. Patient recovered.
Topotecan Side Effects Report #5390075-8
Physician from UNITED STATES reported TOPOTECAN problem on July 16, 2007. Female patient, 70 years of age, was diagnosed with depression, nausea, pain and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, thrombocytopenia, urinary tract infection. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, CELEXA, CARDIZEM, MS CONTIN, PHENERGAN, DILAUDID. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5392393-6
TOPOTECAN problem was reported by a Physician from KOREA, REPUBLIC OF on Apr 27, 2005. Male patient, 66 years of age, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, hepatic enzyme increased, leukopenia, neutropenia, thrombocytopenia. TOPOTECAN dosage: 1.2MGM2 PER DAY. During the same period patient was treated with ETOPOSIDE, METOCLOPRAMIDE, DEXAMETHASONE, ONDANSETRON, AMINO ACIDS, CODEIN, MEFENAMIC ACID. Patient died.
Topotecan Side Effects Report #5392420-6
Physician from GERMANY reported TOPOTECAN problem on July 13, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: malaise. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5392427-9
TOPOTECAN problem was reported by a Physician from GERMANY on July 17, 2007. Female patient, weighting 178.6 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, pancytopenia, pyrexia, urinary tract infection. TOPOTECAN dosage: 2.43MG PER DAY. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5397758-4
Physician from GERMANY reported TOPOTECAN problem on July 19, 2007. Male patient, 62 years of age, weighting 185.4 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: dehydration, gastric haemorrhage, headache, metastases to central nervous system, pancytopenia, renal failure, somnolence, vertigo, vomiting. TOPOTECAN dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, DEXAMETHASONE. Patient was hospitalized. Patient died on 08/05/2005.
Topotecan Side Effects Report #5399272-9
TOPOTECAN problem was reported by a Physician from GERMANY on July 20, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: hospitalisation, malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.
Topotecan Side Effects Report #5400399-3
Physician from GERMANY reported TOPOTECAN problem on July 20, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: hospitalisation, malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.
Topotecan Side Effects Report #5400444-5
TOPOTECAN problem was reported by a Consumer or non-health professional from UNITED KINGDOM on July 20, 2007. Female patient, 67 years of age, weighting 167.1 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: bronchospasm, hypertension, hypoxia. TOPOTECAN dosage: unknown. During the same period patient was treated with ASPIRIN, HUMALOG, METOCLOPRAMIDE. Patient was hospitalized and became disabled. Patient recovered.
Topotecan Side Effects Report #5402709-X
Physician from JAPAN reported TOPOTECAN problem on July 23, 2007. Female patient, 64 years of age, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: leukaemia. TOPOTECAN dosage: 1.2MGM2 PER DAY. During the same period patient was treated with DOXORUBICIN, DOCETAXEL, CARBOPLATIN, PACLITAXEL. Patient recovered.
Topotecan Side Effects Report #5406698-3
TOPOTECAN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 03, 2007. Female patient, weighting 134.1 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, chills, constipation, hydronephrosis, nausea, pyelonephritis, pyrexia, vomiting. TOPOTECAN dosage: 15.9 MG. During the same period patient was treated with COUMADIN, FENTANYL, MS CONTIN, PERCOCET. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5408211-3
Consumer or non-health professional from UNITED STATES reported TOPOTECAN problem on Aug 06, 2007. Female patient, weighting 134.1 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: flank pain, implant site pain. TOPOTECAN dosage: 15.9 MG. During the same period patient was treated with CIPRO, FENTANYL, LOVENOX, NICODERM, PERCOCET. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5408736-0
TOPOTECAN problem was reported by a Physician from GERMANY on July 31, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.
Topotecan Side Effects Report #5409431-4
Consumer or non-health professional from UNITED STATES reported TOPOTECAN problem on Aug 07, 2007. Female patient, weighting 134.1 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain lower, culture urine positive, diarrhoea, flank pain, ill-defined disorder, trichosporon infection. TOPOTECAN dosage: 15.9 MG. During the same period patient was treated with CIPRO, FENTANYL, LOVENOX, NICODERM, PERCOCET, PHENERGAN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5409691-X
TOPOTECAN problem was reported by a Health Professional from UNITED STATES on Aug 08, 2007. Female patient, weighting 134.1 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: bacteria urine identified, diarrhoea, flank pain, frequent bowel movements, trichosporon infection. TOPOTECAN dosage: unknown. During the same period patient was treated with LOVENOX, CIPRO, FENTANYL, FLAGYL, NICODERM, PERCOCET, PHENERGAN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5409729-X
Physician from GERMANY reported TOPOTECAN problem on Aug 01, 2007. Female patient, 59 years of age, weighting 130.1 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: subileus. TOPOTECAN dosage: 4MG WEEKLY. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5412525-0
TOPOTECAN problem was reported by a Physician from GERMANY on Aug 03, 2007. Female patient, weighting 174.2 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: ileus. TOPOTECAN dosage: 7.5MG WEEKLY. Patient died on 04/19/2006.
Topotecan Side Effects Report #5415548-0
Physician from GERMANY reported TOPOTECAN problem on Aug 10, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.
Topotecan Side Effects Report #5416732-2
TOPOTECAN problem was reported by a Physician from JAPAN on Aug 10, 2007. Female patient, 64 years of age, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia. TOPOTECAN dosage: 1.2MGM2 PER DAY. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, DOXIL, DOCETAXEL, FLUCONAZOLE, NEUPOGEN. Patient recovered.
Topotecan Side Effects Report #5417768-8
Pharmacist from UNITED STATES reported TOPOTECAN problem on Aug 15, 2007. Female patient, weighting 147.0 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: pancytopenia, pyrexia. TOPOTECAN dosage: unknown. During the same period patient was treated with NEUPOGEN, COUMADIN, LACTULOSE, TOPROL, NYSTATIN, LASIX, PROTONIX. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5419504-8
TOPOTECAN problem was reported by a Health Professional from UNITED STATES on Aug 17, 2007. Female patient was diagnosed with small cell carcinoma and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased. TOPOTECAN dosage: 3 MG/M2 D1,8,15 Q 28 DAYS IV. During the same period patient was treated with VELCADE. Patient died on 06/28/2007.
Topotecan Side Effects Report #5421056-3
Physician from UNITED STATES reported TOPOTECAN problem on Aug 16, 2007. Female patient, 78 years of age, weighting 140.2 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, arthralgia, dyspnoea, fall, gastrointestinal haemorrhage, haematuria, muscular weakness, platelet count decreased. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, NEULASTA. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5422395-2
TOPOTECAN problem was reported by a Physician from UNITED STATES on Aug 20, 2007. Male patient, 83 years of age, weighting 188.5 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: accidental poisoning, dehydration, dysuria, fatigue, nausea, renal failure acute, vomiting. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5427580-1
Consumer or non-health professional from UNITED STATES reported TOPOTECAN problem on Aug 20, 2007. Female patient was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: caecitis, febrile neutropenia. TOPOTECAN dosage: 1.5MGM2 CYCLIC. During the same period patient was treated with PACLITAXEL, ETOPOSIDE, FILGRASTIM. Patient died.
Topotecan Side Effects Report #5444895-1
TOPOTECAN problem was reported by a Physician from UNITED STATES on Sept 04, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, asthenia, dyspnoea, tachycardia. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5453813-1
Physician from UNITED STATES reported TOPOTECAN problem on Sept 12, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, asthenia, cardio-respiratory arrest, dyspnoea, tachycardia. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 09/05/2007.
Topotecan Side Effects Report #5453892-1
TOPOTECAN problem was reported by a Physician from GERMANY on Sept 12, 2007. Female patient, weighting 271.2 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: agitation, dyspnoea, erythema, hypersensitivity. TOPOTECAN dosage: 1.5MG PER DAY. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5456547-2
Physician from GERMANY reported TOPOTECAN problem on Sept 12, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.
Topotecan Side Effects Report #5463220-3
TOPOTECAN problem was reported by a Physician from GERMANY on Sept 17, 2007. Female patient, weighting 271.2 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: agitation, dyspnoea, erythema, flushing, hypersensitivity. TOPOTECAN dosage: 1.5MG PER DAY. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5465782-9
Physician from GERMANY reported TOPOTECAN problem on Sept 17, 2007. Female patient, 67 years of age, weighting 167.6 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: haematuria, pancytopenia, pyrexia. TOPOTECAN dosage: .75MGM2 SEE TEXT. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5468320-X
TOPOTECAN problem was reported by a Physician from UNITED STATES on Sept 25, 2007. Male patient, 83 years of age, weighting 188.5 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: accidental poisoning, dehydration, disease progression, dysuria, fatigue, nausea, pneumonia, renal failure acute, vomiting. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 08/25/2007.
Topotecan Side Effects Report #5468357-0
Physician from GERMANY reported TOPOTECAN problem on Sept 20, 2007. Female patient, weighting 271.2 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: agitation, dyspnoea, erythema, flushing, hypersensitivity. TOPOTECAN dosage: 1.5MG PER DAY. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.
Topotecan Side Effects Report #5469740-X
TOPOTECAN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 26, 2007. Female patient, weighting 136.7 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, escherichia infection, kidney infection, urinary tract infection. TOPOTECAN dosage: 18 MG. Patient was hospitalized. Patient recovered.
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