TOPOTECAN Side Effects

7020633-6 | Blood Creatinine Increased
on Sep 21, 2010 Female patient from GERMANY , weighting 185.2 lb, was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: blood creatinine increased. Topotecan dosage: .75mgm2 Cyclic. During the same period patient was treated with CISPLATIN (50mgm2 Cyclic) (View Cisplatin Review and Cisplatin Label ), PARKEMED (500mg Seven Times Per Day) (View Parkemed Review and Parkemed Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ). Patient was hospitalized.

7020630-0 | Gait Disturbance, Muscular Weakness
Patient was taking Topotecan (View Usage). Patient had the following side effects: gait disturbance, muscular weakness on Sep 21, 2010 from GERMANY Additional patient health information: Female patient , 48 years of age, weighting 239.2 lb, . Topotecan dosage: 3.1mg Every 3 Weeks. During the same period patient was treated with METOCLOPRAMIDE (View Metoclopramide Review and Metoclopramide Label ), TRIAMTERENE AND HYDROCHLOROTHIAZIDE (View Triamterene And Hydrochlorothiazide Review and Triamterene And Hydrochlorothiazide Label ), NEURONTIN (View Neurontin Review and Neurontin Label ), IBUPROFEN (View Ibuprofen Review and Ibuprofen Label ), PANTOPRAZOLE SODIUM (40mg Per Day) (View Pantoprazole Sodium Review and Pantoprazole Sodium Label ), SODIUM CHLORIDE 0.9% (View Sodium Chloride 0.9% Review and Sodium Chloride 0.9% Label ), OSMOFUNDIN (View Osmofundin Review and Osmofundin Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ). Patient was hospitalized.

7010295-6 | Anaemia, Epistaxis, International Normalised Ratio Increased, Neutropenia, Pancytopenia, Thrombocytopenia, Vaginal Haemorrhage
Adverse event was reported on Sep 16, 2010 by a Female patient taking Topotecan (View Usage) (Dosage: ) was diagnosed with endometrial cancer, coagulopathy and. Location: UNITED STATES , 45 years of age, After Topotecan was administered, patient had the following side effects: anaemia, epistaxis, international normalised ratio increased, neutropenia, pancytopenia, thrombocytopenia, vaginal haemorrhage. During the same period patient was treated with COUMADIN (View Coumadin Review and Coumadin Label ), COLACE (View Colace Review and Colace Label ), DILAUDID (View Dilaudid Review and Dilaudid Label ), DURAGESIC 100 (View Duragesic-100 Review and Duragesic-100 Label ), LASIX (20mg Per Day) (View Lasix Review and Lasix Label ), MIRALAX (1unit Per Day) (View Miralax Review and Miralax Label ), PHENERGAN (25mg As Required) (View Phenergan Review and Phenergan Label ). Patient was hospitalized.

7005546-8 | Anaemia, Pulmonary Embolism, Pyrexia
on Sep 16, 2010 Female patient from UNITED STATES , 58 years of age, was diagnosed with hypertension and was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: anaemia, pulmonary embolism (What is pulmonary embolism?), pyrexia. Topotecan dosage: 1.2mgm2 Cyclic. During the same period patient was treated with NORVASC (10mg Per Day) (View Norvasc Review and Norvasc Label ), ENALAPRIL (40mg Per Day) (View Enalapril Review and Enalapril Label ), HYDROCHLOROTHIAZIDE (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ), TYLENOL W/ CODEINE (View Tylenol W/ Codeine Review and Tylenol W/ Codeine Label ), ZOFRAN (View Zofran Review and Zofran Label ), EFFEXOR (75mg Per Day) (View Effexor Review and Effexor Label ).


6992871-X | Blood Creatinine Increased
on Sep 10, 2010 Female patient from GERMANY , weighting 185.2 lb, was treated with Topotecan (View Usage). Patient had the following side effects: blood creatinine increased. Topotecan dosage: .75mgm2 Cyclic. During the same period patient was treated with CISPLATIN (50mgm2 Cyclic) (View Cisplatin Review and Cisplatin Label ), PARKEMED (500mg Seven Times Per Day) (View Parkemed Review and Parkemed Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ). Patient was hospitalized.

6988135-0 | Anaemia, Fatigue, Pyrexia
Patient was taking Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: anaemia, fatigue, pyrexia on Sep 13, 2010 from NETHERLANDS Additional patient health information: Female patient , weighting 261.2 lb, was diagnosed with neoplasm and. Topotecan dosage: 10mg Cyclic. During the same period patient was treated with PAZOPANIB (800mg Per Day) (View Pazopanib Review and Pazopanib Label ). Patient was hospitalized.

6985475-6 | Bacterial Test Positive, Blood Creatinine Increased, Oedema Peripheral, Pain In Extremity, Paraneoplastic Syndrome, Venous Thrombosis Limb, White Blood Cells Urine Positive
Adverse event was reported on Sep 07, 2010 by a Female patient taking Topotecan (View Usage) (Dosage: ) . Location: GERMANY , weighting 125.7 lb, Patient experienced the following unwanted or unexpected effects: bacterial test positive, blood creatinine increased, oedema peripheral, pain in extremity, paraneoplastic syndrome, venous thrombosis limb, white blood cells urine positive. During the same period patient was treated with CISPLATIN (View Cisplatin Review and Cisplatin Label ), ARANESP (150mcg Per Day) (View Aranesp Review and Aranesp Label ), NEULASTA (6mg Per Day) (View Neulasta Review and Neulasta Label ). Patient was hospitalized.

6976830-9 | Dyspnoea
on Sep 02, 2010 Male patient from POLAND , weighting 130.1 lb, was treated with Topotecan (View Usage). Patient had the following side effects: dyspnoea. Topotecan dosage: 1.75mg Per Day. Patient was hospitalized.

6974654-X | Cough, Dyspnoea, Pyrexia, Thrombocytopenia, Wheezing
on Sep 09, 2010 Male patient from UNITED STATES , 54 years of age, was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: cough, dyspnoea, pyrexia, thrombocytopenia, wheezing. Topotecan dosage: 2.7 Mg Other Iv. Patient was hospitalized.

6971912-X | Blood Culture Positive, Febrile Neutropenia, Hypotension, Mental Status Changes, Pancytopenia, Pseudomonal Bacteraemia
Patient was taking Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: blood culture positive, febrile neutropenia, hypotension, mental status changes, pancytopenia, pseudomonal bacteraemia on Sep 08, 2010 from UNITED STATES Additional patient health information: Male patient , 63 years of age, weighting 208.6 lb, was diagnosed with metastases to liver, neuroendocrine tumour and. Topotecan dosage: . Patient was hospitalized.

6965480-6 | Hyperglycaemia, Leukopenia, Neutropenia, Pancytopenia, Thrombocytopenia, Type 2 Diabetes Mellitus
Adverse event was reported on Aug 26, 2010 by a Female patient taking Topotecan (View Usage) (Dosage: 1.49mg Cyclic) . Location: GERMANY , weighting 209.4 lb, Patient had the following side effects: hyperglycaemia, leukopenia, neutropenia, pancytopenia, thrombocytopenia, type 2 diabetes mellitus. During the same period patient was treated with CISPLATIN (99.5mg Cyclic) (View Cisplatin Review and Cisplatin Label ). Patient was hospitalized.

6961371-5 | Hyperglycaemia
on Aug 25, 2010 Female patient from GERMANY , weighting 209.4 lb, was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: hyperglycaemia. Topotecan dosage: 1.49mg Cyclic. During the same period patient was treated with CISPLATIN (99.5mg Cyclic) (View Cisplatin Review and Cisplatin Label ). Patient was hospitalized.

6961352-1 | Leukopenia, Neutropenia, Pain, Pyrexia
on Aug 25, 2010 Female patient from GERMANY , weighting 191.6 lb, was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: leukopenia, neutropenia, pain (What is pain?), pyrexia. Topotecan dosage: 134.4mg Cyclic. During the same period patient was treated with PACLITAXEL (3.36mg Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6945769-7 | Neutropenic Sepsis, Pneumonia
Patient was taking Topotecan (View Usage). Patient had the following side effects: neutropenic sepsis, pneumonia (What is pneumonia?) on Aug 19, 2010 from UNITED KINGDOM Additional patient health information: Female patient , 52 years of age, weighting 147.7 lb, was diagnosed with small cell carcinoma and. Topotecan dosage: 9.5mgm2 Per Day.

6930510-4 | Febrile Neutropenia, Lymphopenia, Pain In Extremity, Thrombocytopenia
Adverse event was reported on Aug 11, 2010 by a Male patient taking Topotecan (View Usage) (Dosage: ) was diagnosed with neoplasm and. Location: UNITED STATES , child 6 years of age, weighting 85.10 lb, After Topotecan was administered, patient had the following side effects: febrile neutropenia, lymphopenia, pain in extremity, thrombocytopenia. During the same period patient was treated with CYCLOPHOSPHAMIDE (View Cyclophosphamide Review and Cyclophosphamide Label ), BACTRIM (View Bactrim Review and Bactrim Label ), MORPHINE (View Morphine Review and Morphine Label ), RADIATION (View Radiation Review and Radiation Label ), NEUPOGEN (View Neupogen Review and Neupogen Label ), CEFEPIME (View Cefepime Review and Cefepime Label ). Patient was hospitalized.

6923661-1 | Abdominal Pain, Anxiety, Faecaloma, Ileus, Subileus, Vomiting
on Aug 05, 2010 Female patient from GERMANY , weighting 114.6 lb, was diagnosed with ovarian cancer recurrent, back pain (What is back pain?), constipation (What is constipation?) and was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), anxiety (What is anxiety?), faecaloma, ileus, subileus, vomiting. Topotecan dosage: 1.55mg Cyclic. During the same period patient was treated with DURAGESIC 100 (25mcg Per Day) (View Duragesic-100 Review and Duragesic-100 Label ), METHYLNALTREXONE BROMIDE (12mg Per Day) (View Methylnaltrexone Bromide Review and Methylnaltrexone Bromide Label ). Patient was hospitalized.

6921283-X | Ascites, Constipation, Ileus, Nausea, Pancytopenia, Subileus
on Aug 06, 2010 Female patient from GERMANY , 55 years of age, weighting 147.7 lb, was treated with Topotecan (View Usage). Patient had the following side effects: ascites, constipation (What is constipation?), ileus, nausea (What is nausea?), pancytopenia, subileus. Topotecan dosage: 1.36mg Per Day. During the same period patient was treated with CARBOPLATIN (701mg Cyclic) (View Carboplatin Review and Carboplatin Label ). Patient was hospitalized.

6921280-4 | Atrial Flutter, Leukopenia, Neutropenia, Respiratory Tract Infection, Thrombocytopenia
Patient was taking Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: atrial flutter, leukopenia, neutropenia, respiratory tract infection, thrombocytopenia on Aug 05, 2010 from SPAIN Additional patient health information: Male patient , weighting 151.5 lb, was diagnosed with chronic obstructive pulmonary disease, prophylaxis and. Topotecan dosage: . During the same period patient was treated with AVANDAMET (View Avandamet Review and Avandamet Label ), DIAMICRON (View Diamicron Review and Diamicron Label ), TIOTROPIUM BROMIDE (View Tiotropium Bromide Review and Tiotropium Bromide Label ), ANASMA (View Anasma Review and Anasma Label ), BISOPROLOL (View Bisoprolol Review and Bisoprolol Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), TORSEMIDE (View Torsemide Review and Torsemide Label ). Patient was hospitalized.

6914255-2 | Disease Progression, Hyperbilirubinaemia, Hyponatraemia
Adverse event was reported on Aug 03, 2010 by a Male patient taking Topotecan (View Usage) (Dosage: 1.2mgm2 Variable Dose) . Location: UNITED STATES , 40 years of age, weighting 313.1 lb, Patient experienced the following unwanted or unexpected effects: disease progression, hyperbilirubinaemia, hyponatraemia. During the same period patient was treated with VELIPARIB (160mg Cumulative Dose) (View Veliparib Review and Veliparib Label ), CARBOPLATIN (2050mg Cumulative Dose) (View Carboplatin Review and Carboplatin Label ), CYTARABINE (View Cytarabine Review and Cytarabine Label ), CLOFARABINE (View Clofarabine Review and Clofarabine Label ). Patient was hospitalized.

6862828-8 | Acute Respiratory Distress Syndrome, Cerebrovascular Accident, Convulsion, Encephalopathy, Pneumonia Aspiration, Pneumothorax Traumatic, Septic Shock
on Jul 13, 2010 Female patient from UNITED STATES , 58 years of age, weighting 112.2 lb, was diagnosed with glioblastoma and was treated with Topotecan (View Usage). Patient had the following side effects: acute respiratory distress syndrome, cerebrovascular accident, convulsion, encephalopathy, pneumonia aspiration, pneumothorax traumatic, septic shock. Topotecan dosage: . During the same period patient was treated with AVASTIN (509mg Every Two Weeks) (View Avastin Review and Avastin Label ), TEMODAR (300mg Per Day) (View Temodar Review and Temodar Label ), RADIATION (View Radiation Review and Radiation Label ), ZOFRAN (View Zofran Review and Zofran Label ), PROTONIX (40mg Per Day) (View Protonix Review and Protonix Label ), MIRALAX (View Miralax Review and Miralax Label ), MULTI VITAMIN (View Multi-vitamin Review and Multi-vitamin Label ), MEDROL (View Medrol Review and Medrol Label ). Patient was hospitalized.

6860576-1 | Pain
on Jul 14, 2010 Female patient from GERMANY , weighting 191.6 lb, was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: pain (What is pain?). Topotecan dosage: 134.4mg Cyclic. During the same period patient was treated with PACLITAXEL (3.36mg Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6860489-5 | Acute Respiratory Distress Syndrome, Convulsion, Encephalopathy, Pneumonia Aspiration, Pneumothorax Traumatic, Septic Shock
Patient was taking Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: acute respiratory distress syndrome, convulsion, encephalopathy, pneumonia aspiration, pneumothorax traumatic, septic shock on Jul 12, 2010 from UNITED STATES Additional patient health information: Female patient , 58 years of age, weighting 112.2 lb, was diagnosed with glioblastoma and. Topotecan dosage: . During the same period patient was treated with AVASTIN (509mg Every Two Weeks) (View Avastin Review and Avastin Label ), TEMODAR (300mg Per Day) (View Temodar Review and Temodar Label ), RADIATION (View Radiation Review and Radiation Label ), ZOFRAN (View Zofran Review and Zofran Label ), PROTONIX (40mg Per Day) (View Protonix Review and Protonix Label ), MIRALAX (View Miralax Review and Miralax Label ), MULTI VITAMIN (View Multi-vitamin Review and Multi-vitamin Label ), MEDROL (View Medrol Review and Medrol Label ). Patient was hospitalized.

6836196-1 | Agitation, Anaemia, Asthenia, Culture Urine Positive, Escherichia Infection, Hyperchloraemia, Hypernatraemia, Hypotension, Mental Status Changes
Adverse event was reported on Jul 12, 2010 by a Female patient taking Topotecan (View Usage) (Dosage: 13.4 Mg) . Location: UNITED STATES , weighting 137.6 lb, Patient had the following side effects: agitation, anaemia, asthenia, culture urine positive, escherichia infection, hyperchloraemia, hypernatraemia, hypotension, mental status changes. Patient was hospitalized.

6836026-8 | Anaemia, Thrombocytopenia
on Jul 07, 2010 Male patient from SPAIN , weighting 151.5 lb, was diagnosed with chronic obstructive pulmonary disease, prophylaxis and was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: anaemia, thrombocytopenia. Topotecan dosage: 1.25mgm2 Cyclic. During the same period patient was treated with AVANDAMET (4000mg Per Day) (View Avandamet Review and Avandamet Label ), DIAMICRON (80mg Per Day) (View Diamicron Review and Diamicron Label ), TIOTROPIUM BROMIDE (View Tiotropium Bromide Review and Tiotropium Bromide Label ), ANASMA (View Anasma Review and Anasma Label ), BISOPROLOL (2.5mg Per Day) (View Bisoprolol Review and Bisoprolol Label ), OMEPRAZOLE (20mg Per Day) (View Omeprazole Review and Omeprazole Label ), TORSEMIDE (5mg Per Day) (View Torsemide Review and Torsemide Label ). Patient was hospitalized.

6823032-2 | Anaemia, Asthenia, Fatigue, Platelet Count Decreased, White Blood Cell Count Decreased
on Jul 05, 2010 Female patient from DENMARK , weighting 139.8 lb, was diagnosed with atrial fibrillation (What is atrial fibrillation?) and was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: anaemia, asthenia, fatigue, platelet count decreased, white blood cell count decreased. Topotecan dosage: . During the same period patient was treated with OXYCONTIN (120mg Three Times Per Day) (View Oxycontin Review and Oxycontin Label ), METHADONE (90mg Three Times Per Day) (View Methadone Review and Methadone Label ), DURAGESIC 100 (6600ug Per Day) (View Duragesic-100 Review and Duragesic-100 Label ), GABAPENTIN (View Gabapentin Review and Gabapentin Label ), SELOZOK (100mg Twice Per Day) (View Selozok Review and Selozok Label ), NEXIUM (80mg Twice Per Day) (View Nexium Review and Nexium Label ), ZOPICLONE (7.5mg Per Day) (View Zopiclone Review and Zopiclone Label ), PINEX (1g As Required) (View Pinex Review and Pinex Label ). Patient was hospitalized.

6801430-0 | Acute Respiratory Failure, Bronchitis, Pneumonia
Patient was taking Topotecan (View Usage). Patient had the following side effects: acute respiratory failure, bronchitis (What is bronchitis?), pneumonia (What is pneumonia?) on Jun 21, 2010 from UNITED STATES Additional patient health information: Male patient , 68 years of age, weighting 249.8 lb, . Topotecan dosage: 2.3mgm2 Cyclic. During the same period patient was treated with BEVACIZUMAB (15mgk Cyclic) (View Bevacizumab Review and Bevacizumab Label ). Patient was hospitalized.

6779659-X | Acute Respiratory Failure, Bronchitis, Pneumonia
Adverse event was reported on Jun 15, 2010 by a Male patient taking Topotecan (View Usage) (Dosage: 2.3mgm2 Cyclic) . Location: UNITED STATES , 68 years of age, weighting 249.8 lb, After Topotecan was administered, patient had the following side effects: acute respiratory failure, bronchitis (What is bronchitis?), pneumonia (What is pneumonia?). During the same period patient was treated with BEVACIZUMAB (15mgk Cyclic) (View Bevacizumab Review and Bevacizumab Label ). Patient was hospitalized.

6779577-7 | Pancytopenia, Pneumonitis, Respiratory Failure
on Jun 16, 2010 Female patient from UNITED STATES , 58 years of age, weighting 112.2 lb, was diagnosed with glioblastoma and was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: pancytopenia, pneumonitis, respiratory failure. Topotecan dosage: . During the same period patient was treated with AVASTIN (509mg Every Two Weeks) (View Avastin Review and Avastin Label ), TEMODAR (View Temodar Review and Temodar Label ), RADIATION (View Radiation Review and Radiation Label ), HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label ). Patient was hospitalized.

6779572-8 | Anaemia, Nausea
on Jun 12, 2010 Male patient from POLAND , weighting 114.6 lb, was treated with Topotecan (View Usage). Patient had the following side effects: anaemia, nausea (What is nausea?). Topotecan dosage: 2.3mgm2 Per Day. During the same period patient was treated with RADIATION (3gy Per Day) (View Radiation Review and Radiation Label ). Patient was hospitalized.

6768001-6 | Pancytopenia, Pneumonia Cytomegaloviral, Respiratory Failure
Patient was taking Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: pancytopenia, pneumonia cytomegaloviral, respiratory failure on Jun 08, 2010 from UNITED STATES Additional patient health information: Female patient , 58 years of age, weighting 112.2 lb, was diagnosed with glioblastoma and. Topotecan dosage: . During the same period patient was treated with AVASTIN (509mg Every Two Weeks) (View Avastin Review and Avastin Label ), TEMODAR (View Temodar Review and Temodar Label ), RADIATION (View Radiation Review and Radiation Label ), HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label ). Patient was hospitalized.

6766009-8 | Dyspnoea Exertional, Nausea
Adverse event was reported on Jun 03, 2010 by a Male patient taking Topotecan (View Usage) (Dosage: 2.3mgm2 Per Day) . Location: POLAND , weighting 114.6 lb, Patient experienced the following unwanted or unexpected effects: dyspnoea exertional, nausea (What is nausea?). During the same period patient was treated with RADIATION (3gy Per Day) (View Radiation Review and Radiation Label ). Patient was hospitalized.

6762670-2 | Cerebral Haemorrhage, Coma, Thrombocytopenia
on Jun 04, 2010 Male patient from UNITED KINGDOM , weighting 199.3 lb, was diagnosed with ewing's sarcoma, pain (What is pain?), asthma (What is asthma?) and was treated with Topotecan (View Usage). Patient had the following side effects: cerebral haemorrhage, coma, thrombocytopenia. Topotecan dosage: 1.6mg Cyclic. During the same period patient was treated with CYCLOPHOSPHAMIDE (510mg Per Day) (View Cyclophosphamide Review and Cyclophosphamide Label ), RAPAMUNE (8mg Per Day) (View Rapamune Review and Rapamune Label ), MORPHINE (View Morphine Review and Morphine Label ), ORAMORPH SR (View Oramorph Sr Review and Oramorph Sr Label ), SYMBICORT (View Symbicort Review and Symbicort Label ), GABAPENTIN (View Gabapentin Review and Gabapentin Label ). Patient was hospitalized.

6753958-X | Deep Vein Thrombosis, Pancytopenia, Pulmonary Embolism, Thrombocytopenia
on May 21, 2010 Female patient from UNITED STATES , 61 years of age, weighting 239.2 lb, was diagnosed with glioblastoma multiforme and was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: deep vein thrombosis (What is deep vein thrombosis?), pancytopenia, pulmonary embolism (What is pulmonary embolism?), thrombocytopenia. Topotecan dosage: 5mgm2 Cyclic. During the same period patient was treated with TEMOZOLOMIDE (200mgm2 Cyclic) (View Temozolomide Review and Temozolomide Label ), BEVACIZUMAB (10mgk Every Two Weeks) (View Bevacizumab Review and Bevacizumab Label ), KEPPRA (View Keppra Review and Keppra Label ), PEPCID (View Pepcid Review and Pepcid Label ), HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label ), AMBIEN (View Ambien Review and Ambien Label ), FLONASE (View Flonase Review and Flonase Label ). Patient was hospitalized.

6728170-0 | Blood Creatinine Increased, Blood Phosphorus Increased, Blood Uric Acid Increased, Confusional State, Dermatitis Exfoliative, Exfoliative Rash, Hyperbilirubinaemia, Hypocalcaemia
Patient was taking Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: blood creatinine increased, blood phosphorus increased, blood uric acid increased, confusional state, dermatitis exfoliative, exfoliative rash, hyperbilirubinaemia, hypocalcaemia on May 13, 2010 from UNITED STATES Additional patient health information: Male patient , 65 years of age, weighting 225.5 lb, was diagnosed with neoplasm and. Topotecan dosage: 1.2mgm2 Continuous. During the same period patient was treated with VELIPARIB (20mg Twice Per Day) (View Veliparib Review and Veliparib Label ), CARBOPLATIN (120mgm2 Continuous) (View Carboplatin Review and Carboplatin Label ), BEXAROTENE (View Bexarotene Review and Bexarotene Label ), VANCOMYCIN (View Vancomycin Review and Vancomycin Label ), ZOSYN (View Zosyn Review and Zosyn Label ), MEROPENEM (View Meropenem Review and Meropenem Label ), LINEZOLID (View Linezolid Review and Linezolid Label ), CLINDAMYCIN (View Clindamycin Review and Clindamycin Label ).

6726363-X | Chronic Obstructive Pulmonary Disease
Adverse event was reported on May 11, 2010 by a Male patient taking Topotecan (View Usage) (Dosage: 2.3mgm2 Cyclic) . Location: POLAND , weighting 114.6 lb, Patient had the following side effects: chronic obstructive pulmonary disease. During the same period patient was treated with RADIATION (3gy Per Day) (View Radiation Review and Radiation Label ). Patient was hospitalized.

6719782-9 | Neutropenic Sepsis, Pneumonia
on May 05, 2010 Female patient from UNITED KINGDOM , 52 years of age, weighting 147.7 lb, was diagnosed with small cell carcinoma and was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: neutropenic sepsis, pneumonia (What is pneumonia?). Topotecan dosage: 9.5mgm2 Per Day.

6716062-2 | Confusional State, Dyspnoea, Febrile Neutropenia, Pneumonia, Sepsis, Thrombocytopenia
on May 03, 2010 Male patient from CANADA , weighting 150.4 lb, was diagnosed with non-small cell lung cancer and was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: confusional state, dyspnoea, febrile neutropenia, pneumonia (What is pneumonia?), sepsis (What is sepsis?), thrombocytopenia. Topotecan dosage: 1.1mgm2 Per Day. During the same period patient was treated with RADIATION (3gy Per Day) (View Radiation Review and Radiation Label ). Patient was hospitalized.

6696618-6 | Febrile Neutropenia, Lymphopenia, Pain In Extremity, Thrombocytopenia
Patient was taking Topotecan (View Usage). Patient had the following side effects: febrile neutropenia, lymphopenia, pain in extremity, thrombocytopenia on Apr 19, 2010 from UNITED STATES Additional patient health information: Male patient , child 6 years of age, weighting 85.10 lb, was diagnosed with neoplasm and. Topotecan dosage: . During the same period patient was treated with CYCLOPHOSPHAMIDE (View Cyclophosphamide Review and Cyclophosphamide Label ), BACTRIM (View Bactrim Review and Bactrim Label ), MORPHINE (View Morphine Review and Morphine Label ), RADIATION (View Radiation Review and Radiation Label ). Patient was hospitalized.

6690568-7 | Abdominal Pain, Dehydration, Nausea, Small Intestinal Obstruction
Adverse event was reported on Jan 19, 2010 by a Female patient taking Topotecan (View Usage) (Dosage: 12mg Cyclic) was diagnosed with hypertension and. Location: UNITED STATES , 74 years of age, weighting 132.3 lb, After Topotecan was administered, patient had the following side effects: abdominal pain (What is abdominal pain?), dehydration, nausea (What is nausea?), small intestinal obstruction. During the same period patient was treated with ASPIRIN (View Aspirin Review and Aspirin Label ), MULTI VITAMIN (View Multi-vitamin Review and Multi-vitamin Label ), ACCURETIC (View Accuretic Review and Accuretic Label ), METOPROLOL TARTRATE (View Metoprolol Tartrate Review and Metoprolol Tartrate Label ), COMPAZINE (View Compazine Review and Compazine Label ), MAGNESIUM GLUCONATE (1g Twice Per Day) (View Magnesium Gluconate Review and Magnesium Gluconate Label ), LEVOTHYROXINE (88mg Per Day) (View Levothyroxine Review and Levothyroxine Label ). Patient was hospitalized.

6685089-1 | Intestinal Perforation
on Apr 12, 2010 Male patient from UNITED KINGDOM , 73 years of age, was diagnosed with pain (What is pain?) and was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: intestinal perforation. Topotecan dosage: 4.5mg Per Day. During the same period patient was treated with CLONAZEPAM (2.5mg Per Day) (View Clonazepam Review and Clonazepam Label ), GABAPENTIN (1800mg Per Day) (View Gabapentin Review and Gabapentin Label ), MORPHINE (60mg Per Day) (View Morphine Review and Morphine Label ), FUROSEMIDE (View Furosemide Review and Furosemide Label ), ZOPICLONE (View Zopiclone Review and Zopiclone Label ), MOVICOL (View Movicol Review and Movicol Label ), PARACETAMOL (View Paracetamol Review and Paracetamol Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ).

6682926-1 | Pneumonia, Respiratory Failure
on Apr 13, 2010 Female patient from UNITED STATES , 62 years of age, weighting 157.0 lb, was treated with Topotecan (View Usage). Patient had the following side effects: pneumonia (What is pneumonia?), respiratory failure. Topotecan dosage: 2.3mgm2 Cyclic. During the same period patient was treated with BEVACIZUMAB (15mgk Cyclic) (View Bevacizumab Review and Bevacizumab Label ). Patient was hospitalized.

6681405-5 | Neutropenic Sepsis
Patient was taking Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: neutropenic sepsis on Apr 08, 2010 from UNITED KINGDOM Additional patient health information: Male patient , 64 years of age, . Topotecan dosage: 3mg Per Day.

6666055-9 | Abdominal Pain, Cholecystitis, Leukopenia, Nausea, Neutropenia
Adverse event was reported on Mar 26, 2010 by a Female patient taking Topotecan (View Usage) (Dosage: 1.89mg Cyclic) was diagnosed with ovarian cancer recurrent, pain (What is pain?), breast cancer (What is breast cancer?) and. Location: GERMANY , weighting 108.0 lb, Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), cholecystitis, leukopenia, nausea (What is nausea?), neutropenia. During the same period patient was treated with TILIDIN (50mg Per Day) (View Tilidin Review and Tilidin Label ), FEMARA (2.5mg Per Day) (View Femara Review and Femara Label ), CALCIUM D3 (View Calcium D3 Review and Calcium D3 Label ). Patient was hospitalized.

6658172-4 | Dyspnoea, Leukopenia, Pleural Effusion
on Mar 23, 2010 Female patient from GERMANY , weighting 160.9 lb, was diagnosed with ovarian cancer, hypertension, hypothyroidism, diabetes mellitus and was treated with Topotecan (View Usage). Patient had the following side effects: dyspnoea, leukopenia, pleural effusion. Topotecan dosage: . During the same period patient was treated with NIFEHEXAL (30mg Per Day) (View Nifehexal Review and Nifehexal Label ), RAMIPRIL (2.5mg Per Day) (View Ramipril Review and Ramipril Label ), LEVOTHYROXINE SODIUM (100ug Per Day) (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), GLIBENHEXAL (7mg Per Day) (View Glibenhexal Review and Glibenhexal Label ), INNOHEP (1000unit Per Day) (View Innohep Review and Innohep Label ). Patient was hospitalized.

6649171-7 | Thrombosis
on Mar 16, 2010 Female patient from GERMANY , weighting 147.7 lb, was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: thrombosis. Topotecan dosage: 1.31mg Three Times Per Day. During the same period patient was treated with CARBOPLATIN (383mg Three Times Per Day) (View Carboplatin Review and Carboplatin Label ). Patient was hospitalized.

6647299-9 | Anaemia, Chest Pain, Fatigue
Patient was taking Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: anaemia, chest pain (What is chest pain?), fatigue on Mar 18, 2010 from DENMARK Additional patient health information: Female patient , weighting 138.9 lb, was diagnosed with atrial fibrillation (What is atrial fibrillation?), constipation (What is constipation?) and. Topotecan dosage: 2.6mg Cyclic. During the same period patient was treated with METADON (90mg Three Times Per Day) (View Metadon Review and Metadon Label ), SELOZOK (100mg Twice Per Day) (View Selozok Review and Selozok Label ), NEXIUM (80mg Twice Per Day) (View Nexium Review and Nexium Label ), OXYCODONE HCL (View Oxycodone Hcl Review and Oxycodone Hcl Label ), GABAPENTIN (2700mg Three Times Per Day) (View Gabapentin Review and Gabapentin Label ), ZOPICLONE (7.5mg As Required) (View Zopiclone Review and Zopiclone Label ), ACETAMINOPHEN AND CODEINE PHOSPHATE (1g As Required) (View Acetaminophen And Codeine Phosphate Review and Acetaminophen And Codeine Phosphate Label ), TOILAX (5mg Per Day) (View Toilax Review and Toilax Label ). Patient was hospitalized.

6643034-9 | Cholecystitis, Leukopenia, Neutropenia
Adverse event was reported on Mar 11, 2010 by a Female patient taking Topotecan (View Usage) (Dosage: 1.89mg Cyclic) was diagnosed with ovarian cancer recurrent, pain (What is pain?), breast cancer (What is breast cancer?) and. Location: GERMANY , weighting 108.0 lb, Patient had the following side effects: cholecystitis, leukopenia, neutropenia. During the same period patient was treated with TILIDIN (50mg Per Day) (View Tilidin Review and Tilidin Label ), FEMARA (2.5mg Per Day) (View Femara Review and Femara Label ), CALCIUM D3 (View Calcium D3 Review and Calcium D3 Label ). Patient was hospitalized.

6636690-2 | Thrombosis
on Mar 08, 2010 Female patient from GERMANY , weighting 147.7 lb, was diagnosed with neoplasm malignant and was treated with Topotecan (View Usage). After Topotecan was administered, patient had the following side effects: thrombosis. Topotecan dosage: 1.31mg Three Times Per Day. During the same period patient was treated with CARBOPLATIN (383mg Three Times Per Day) (View Carboplatin Review and Carboplatin Label ). Patient was hospitalized.

6630207-4 | Accidental Overdose, Blood Urea Increased, Confusional State, Decreased Appetite, Dehydration, Haemoglobin Decreased, Hypotension, Somnolence
on Mar 01, 2010 Female patient from UNITED STATES , 66 years of age, weighting 139.1 lb, was diagnosed with metastases to central nervous system and was treated with Topotecan (View Usage). Patient experienced the following unwanted or unexpected effects: accidental overdose, blood urea increased, confusional state, decreased appetite, dehydration, haemoglobin decreased, hypotension, somnolence. Topotecan dosage: 1.1mgm2 Per Day. Patient was hospitalized.

6611963-8 | Abdominal Pain, Constipation, Fistula, Hydronephrosis, Hydroureter, Intestinal Obstruction, Medical Device Complication, Necrosis, Uterine Mass
Patient was taking Topotecan (View Usage). Patient had the following side effects: abdominal pain (What is abdominal pain?), constipation (What is constipation?), fistula (What is fistula?), hydronephrosis, hydroureter, intestinal obstruction, medical device complication, necrosis, uterine mass on Mar 02, 2010 from UNITED STATES Additional patient health information: Female patient , weighting 90.17 lb, . Topotecan dosage: 3.06 Mg. During the same period patient was treated with TAXOL (238 Mg) (View Taxol Review and Taxol Label ). Patient was hospitalized.