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Review Topotecan Safety Reports submitted to FDA

Total Topotecan reports: 121.
Topotecan FDA safety alerts: No.
Reported deaths: 31    Reported hospitalizations: 102.
Take Topotecan Side Effects Survey, Discuss Topotecan with others
FDA Reported Topotecan Side Effects: dehydration, anaemia, dyspnoea, vomiting, nausea, pyrexia, fatigue, neutropenia, thrombocytopenia, pancytopenia, confusional state.
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Showing 1-100 of 121 Next >

Topotecan Side Effects Report #5390075-8
Physician from UNITED STATES reported TOPOTECAN problem on July 16, 2007. Female patient, 70 years of age, was diagnosed with depression, nausea, pain and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, thrombocytopenia, urinary tract infection. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, CELEXA, CARDIZEM, MS CONTIN, PHENERGAN, DILAUDID. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5392393-6
TOPOTECAN problem was reported by a Physician from KOREA, REPUBLIC OF on Apr 27, 2005. Male patient, 66 years of age, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, hepatic enzyme increased, leukopenia, neutropenia, thrombocytopenia. TOPOTECAN dosage: 1.2MGM2 PER DAY. During the same period patient was treated with ETOPOSIDE, METOCLOPRAMIDE, DEXAMETHASONE, ONDANSETRON, AMINO ACIDS, CODEIN, MEFENAMIC ACID. Patient died.

Topotecan Side Effects Report #5392420-6
Physician from GERMANY reported TOPOTECAN problem on July 13, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: malaise. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5392427-9
TOPOTECAN problem was reported by a Physician from GERMANY on July 17, 2007. Female patient, weighting 178.6 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, pancytopenia, pyrexia, urinary tract infection. TOPOTECAN dosage: 2.43MG PER DAY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5397758-4
Physician from GERMANY reported TOPOTECAN problem on July 19, 2007. Male patient, 62 years of age, weighting 185.4 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: dehydration, gastric haemorrhage, headache, metastases to central nervous system, pancytopenia, renal failure, somnolence, vertigo, vomiting. TOPOTECAN dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, DEXAMETHASONE. Patient was hospitalized. Patient died on 08/05/2005.

Topotecan Side Effects Report #5399272-9
TOPOTECAN problem was reported by a Physician from GERMANY on July 20, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: hospitalisation, malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.

Topotecan Side Effects Report #5400399-3
Physician from GERMANY reported TOPOTECAN problem on July 20, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: hospitalisation, malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.

Topotecan Side Effects Report #5400444-5
TOPOTECAN problem was reported by a Consumer or non-health professional from UNITED KINGDOM on July 20, 2007. Female patient, 67 years of age, weighting 167.1 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: bronchospasm, hypertension, hypoxia. TOPOTECAN dosage: unknown. During the same period patient was treated with ASPIRIN, HUMALOG, METOCLOPRAMIDE. Patient was hospitalized and became disabled. Patient recovered.

Topotecan Side Effects Report #5376096-X
Physician from HUNGARY reported TOPOTECAN problem on June 22, 2007. Female patient, 64 years of age, weighting 174.2 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, fatigue, leukopenia, neutropenia, pancytopenia, pyrexia, syncope, thrombocytopenia. TOPOTECAN dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5380752-7
TOPOTECAN problem was reported by a Physician from HUNGARY on July 04, 2007. Female patient, 64 years of age, weighting 174.2 lb, was diagnosed with metastases to central nervous system and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, bedridden, fatigue, heart rate increased, impaired self-care, leukopenia, neutropenia, pancytopenia. TOPOTECAN dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5381970-4
Physician from UNITED STATES reported TOPOTECAN problem on July 05, 2007. Female patient, 70 years of age, was diagnosed with depression, nausea, pain and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, urinary tract infection, vomiting. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, CELEXA, CARDIZEM, MS CONTIN, PHENERGAN, DILAUDID. Patient recovered.

Topotecan Side Effects Report #5384177-X
TOPOTECAN problem was reported by a Physician from HUNGARY on July 06, 2007. Female patient, 64 years of age, weighting 174.2 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, bedridden, fatigue, impaired self-care, leukopenia, neutropenia, pancytopenia, pyrexia. TOPOTECAN dosage: 4MG PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5386556-3
Physician from UNITED STATES reported TOPOTECAN problem on July 09, 2007. Female patient, 70 years of age, was diagnosed with depression, nausea, pain and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, urinary tract infection, vomiting. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, CELEXA, CARDIZEM, MS CONTIN, PHENERGAN, DILAUDID. Patient recovered.

Topotecan Side Effects Report #5390075-8
TOPOTECAN problem was reported by a Physician from UNITED STATES on July 16, 2007. Female patient, 70 years of age, was diagnosed with depression, nausea, pain and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, thrombocytopenia, urinary tract infection. TOPOTECAN dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, CELEXA, CARDIZEM, MS CONTIN, PHENERGAN, DILAUDID. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5392393-6
Physician from KOREA, REPUBLIC OF reported TOPOTECAN problem on Apr 27, 2005. Male patient, 66 years of age, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: anaemia, hepatic enzyme increased, leukopenia, neutropenia, thrombocytopenia. TOPOTECAN dosage: 1.2MGM2 PER DAY. During the same period patient was treated with ETOPOSIDE, METOCLOPRAMIDE, DEXAMETHASONE, ONDANSETRON, AMINO ACIDS, CODEIN, MEFENAMIC ACID. Patient died.

Topotecan Side Effects Report #5392420-6
TOPOTECAN problem was reported by a Physician from GERMANY on July 13, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: malaise. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5392427-9
Physician from GERMANY reported TOPOTECAN problem on July 17, 2007. Female patient, weighting 178.6 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, pancytopenia, pyrexia, urinary tract infection. TOPOTECAN dosage: 2.43MG PER DAY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5397758-4
TOPOTECAN problem was reported by a Physician from GERMANY on July 19, 2007. Male patient, 62 years of age, weighting 185.4 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: dehydration, gastric haemorrhage, headache, metastases to central nervous system, pancytopenia, renal failure, somnolence, vertigo, vomiting. TOPOTECAN dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, DEXAMETHASONE. Patient was hospitalized. Patient died on 08/05/2005.

Topotecan Side Effects Report #5399272-9
Physician from GERMANY reported TOPOTECAN problem on July 20, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: hospitalisation, malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.

Topotecan Side Effects Report #5400399-3
TOPOTECAN problem was reported by a Physician from GERMANY on July 20, 2007. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: hospitalisation, malaise, multi-organ failure. TOPOTECAN dosage: 7.76MG WEEKLY. Patient was hospitalized. Patient died on 07/08/2007.

Topotecan Side Effects Report #5400444-5
Consumer or non-health professional from UNITED KINGDOM reported TOPOTECAN problem on July 20, 2007. Female patient, 67 years of age, weighting 167.1 lb, was treated with TOPOTECAN. After drug was administered, patient experienced the following problems/side effects: bronchospasm, hypertension, hypoxia. TOPOTECAN dosage: unknown. During the same period patient was treated with ASPIRIN, HUMALOG, METOCLOPRAMIDE. Patient was hospitalized and became disabled. Patient recovered.

Showing 1-100 of 121 Next >


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anaemia, chills, dehydration, eating disorder, febrile neutropenia, nausea, pyrexia, thrombocytopenia, urinary tract infection, , was diagnosed with depression, nausea, pain and was diagnosed with ovarian cancer and was diagnosed with ovarian cancer and