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Review Tysabri Safety Reports submitted to FDA

Total Tysabri reports: 1209.
Tysabri FDA safety alerts: 2005 2006 2008 .
Reported deaths: 128    Reported hospitalizations: 807.
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FDA Reported Tysabri Side Effects: multiple sclerosis relapse, condition aggravated, headache, asthenia, infusion related reaction, convulsion, chills, flushing, dyspnoea, fall, urinary tract infection.
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Tysabri Side Effects Report #5628908-X
Physician from UNITED STATES reported TYSABRI problem on Feb 04, 2008. Female patient, 41 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: convulsion, faecal incontinence, flushing, infusion related reaction, panic disorder, unresponsive to stimuli, vein disorder. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5628913-3
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 05, 2008. Male patient, 50 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: choking, dysphagia. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with OIPOIDS. Patient died on 12/31/2007.

Tysabri Side Effects Report #5629019-X
Physician from UNITED STATES reported TYSABRI problem on Feb 06, 2008. Female patient, 47 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: decubitus ulcer, deep vein thrombosis, factor v leiden mutation, protein s deficiency. TYSABRI dosage: 300 MG;QM;IV. During the same period patient was treated with NEXIUM, CYMBALTA, KLONOPIN, BACLOFEN, VITAMIN D, CALCIUM, CRANBERRY SUPPLEMENT, MILK OF MAGNESIA. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5629020-6
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 07, 2008. Female patient, 38 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: localised infection, staphylococcal infection. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.


Tysabri Side Effects Report #5629021-8
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Jan 29, 2008. Female patient, 55 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: hyperplasia, impaired healing, injection site necrosis, open wound, skin necrosis. TYSABRI dosage: 300 MG;QM;IV. During the same period patient was treated with AVONEX, BETASERON. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5629022-X
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 06, 2008. Male patient, 61 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: dyspnoea, infusion related reaction, oxygen saturation decreased. TYSABRI dosage: 300 MG;QM;IV. Patient recovered.

Tysabri Side Effects Report #5629636-7
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Feb 02, 2008. Female patient, 53 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: muscle spasms, oedema peripheral, pain. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5630008-X
TYSABRI problem was reported by a Health Professional from IRELAND on Feb 01, 2008. Female patient, 23 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: mental disorder, mobility decreased, trigeminal neuralgia, vertigo. TYSABRI dosage: unknown. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5630009-1
Physician from GERMANY reported TYSABRI problem on Jan 29, 2008. Female patient, 20 years of age, weighting 132.3 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: fatigue, gliosis, haematoma, headache, malaise, nausea, oral herpes, quadriparesis, skin discolouration. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.


Tysabri Side Effects Report #5630021-2
TYSABRI problem was reported by a Physician from AUSTRIA on Feb 04, 2008. Female patient, 24 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: acute tonsillitis, anaemia, condition aggravated, endocarditis, mitral valve incompetence. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5631501-6
Health Professional from UNITED STATES reported TYSABRI problem on Feb 04, 2008. Male patient, 61 years of age, weighting 162.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: headache, hypotension, syncope. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5631502-8
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 06, 2008. Female patient, 48 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: fall, head injury. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5633088-0
Physician from GERMANY reported TYSABRI problem on Jan 31, 2008. Female patient, 43 years of age, was diagnosed with relapsing-remitting multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: panic attack. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with COPAXONE. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5633089-2
TYSABRI problem was reported by a Physician from GERMANY on Feb 04, 2008. Female patient, 47 years of age, weighting 132.3 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: urinary retention. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with OMEPRAZOLE, METOPROLOL TARTRATE, LACTULOSE. Patient was hospitalized and became disabled. Patient recovered.


Tysabri Side Effects Report #5633090-9
Physician from FRANCE reported TYSABRI problem on Feb 07, 2008. Female patient, 47 years of age, weighting 132.3 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. TYSABRI dosage: 300 MG; QM; IV. Patient died on 01/21/2008.

Tysabri Side Effects Report #5635674-0
TYSABRI problem was reported by a Consumer or non-health professional from GERMANY on Feb 05, 2008. Female patient, 20 years of age, weighting 132.3 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: haematoma, multiple sclerosis relapse, oral herpes. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5635719-8
Physician from GERMANY reported TYSABRI problem on Feb 06, 2008. Female patient, 35 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: toxic epidermal necrolysis. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5635720-4
TYSABRI problem was reported by a Physician from SWITZERLAND on Feb 08, 2008. Female patient, 42 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: ataxia, hydrocephalus. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5635721-6
Health Professional from CANADA reported TYSABRI problem on Feb 12, 2008. Female patient, 53 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: neuralgia. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.


Tysabri Side Effects Report #5636746-7
TYSABRI problem was reported by a Physician from GERMANY on Feb 05, 2008. Male patient, 30 years of age, weighting 209.4 lb, was diagnosed with relapsing-remitting multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: antibody test positive, malaise. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with FLUOXETINE, TROSPI. Patient recovered.

Tysabri Side Effects Report #5637382-9
Health Professional from UNITED STATES reported TYSABRI problem on Feb 05, 2008. Female patient, 42 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: spinal operation. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637391-X
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 06, 2008. Male patient, 53 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: angioplasty. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637392-1
Physician from UNITED STATES reported TYSABRI problem on Feb 04, 2008. Female patient, 50 years of age, weighting 138.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: autoimmune hepatitis. TYSABRI dosage: unknown. During the same period patient was treated with SYNTHROID, TAMOXIFEN. Patient recovered.

Tysabri Side Effects Report #5637427-6
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 04, 2008. Male patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: dialysis, gait disturbance, intervertebral disc protrusion, post procedural complication, renal failure, spinal cord compression. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637720-7
Health Professional from UNITED STATES reported TYSABRI problem on Feb 07, 2008. Female patient, 39 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: anorexia, condition aggravated, depression, failure to thrive, pneumonia. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient died on 12/07/2007.

Tysabri Side Effects Report #5637722-0
TYSABRI problem was reported by a Physician from UNITED STATES on Feb 07, 2008. Male patient, 76 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: respiratory failure. TYSABRI dosage: unknown. Patient was hospitalized. Patient died on 01/31/2008.

Tysabri Side Effects Report #5637723-2
Health Professional from UNITED STATES reported TYSABRI problem on Feb 07, 2008. Female patient, 52 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident, hypersensitivity, myocardial infarction. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637726-8
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 13, 2008. Female patient, 59 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: diverticulitis, malaise, multiple sclerosis. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637727-X
Physician from UNITED STATES reported TYSABRI problem on Feb 12, 2008. Male patient, 43 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, autoimmune hepatitis, back pain, bilirubin conjugated increased, blood alkaline phosphatase increased, blood bilirubin increased, chills, chromaturia. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with SPIRULINA, VITAMIN CAP, PREDNISONE. Patient recovered.

Tysabri Side Effects Report #5637729-3
TYSABRI problem was reported by a Physician from UNITED STATES on Feb 08, 2008. Female patient, 49 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: headache, leukocytosis, pyrexia, staphylococcal bacteraemia. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637760-8
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Feb 07, 2008. Female patient, 27 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: hip arthroplasty, necrosis. TYSABRI dosage: 300 MG;QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637869-9
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 05, 2008. Female patient, 54 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: hospitalisation. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637871-7
Health Professional from UNITED STATES reported TYSABRI problem on Feb 05, 2008. Female patient, 55 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: catheter related complication, opportunistic infection, sepsis, urinary tract infection, vulvovaginal mycotic infection. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637902-4
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 11, 2008. Female patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: cholecystitis infective. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637903-6
Health Professional from UNITED STATES reported TYSABRI problem on Feb 12, 2008. Female patient, 35 years of age, weighting 140.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: migraine, multiple sclerosis. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637904-8
TYSABRI problem was reported by a Physician from UNITED STATES on Feb 13, 2008. Female patient, 39 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, pulmonary embolism. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637905-X
Health Professional from UNITED STATES reported TYSABRI problem on Feb 11, 2008. Female patient, 61 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: arteriosclerosis coronary artery, bronchopneumonia, encephalitis, gastroenteritis viral, gliosis, herpes zoster, meningioma, mental status changes. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with HYDROCHLOROTHIAZIDE, TOPROL, TARKA, ASPIRIN, TOPAMAX, OMEPRAZOLE, POTASSIUM CHLORIDE, OXYBUTIN. Patient died on 12/01/2007.

Tysabri Side Effects Report #5637906-1
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 12, 2008. Female patient, weighting 220.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: meningioma, multiple sclerosis, nuclear magnetic resonance imaging abnormal, optic neuritis. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5637908-5
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Feb 08, 2008. Male patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: abdominal pain, bladder spasm, choroid melanoma, constipation, cystitis, dehydration, depression, hemiparesis, muscle spasticity. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with WELLBUTRIN, VALIUM, SERZONE, LISINOPRIL, RAZADYNE, AMANTADINE, BACLOFEN, FIORINAL. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5638199-1
TYSABRI problem was reported by a Physician from UNITED STATES on Feb 05, 2008. Male patient, 49 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: basal cell carcinoma. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5638201-7
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Feb 08, 2008. Female patient, 44 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: intracranial aneurysm. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5638203-0
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 12, 2008. Male patient, 51 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: chronic lymphocytic leukaemia. TYSABRI dosage: unknown. Patient recovered.

Tysabri Side Effects Report #5638210-8
Health Professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Female patient, 47 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: endometrial cancer stage i, ovarian epithelial cancer stage iii. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5638212-1
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 13, 2008. Female patient, 67 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: dyspepsia. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with AVONEX. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5638215-7
Health Professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Female patient, 26 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: convulsion. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5638217-0
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 12, 2008. Female patient, 39 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, ear pain, headache, heart rate increased, nasopharyngitis, urinary tract infection. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5638221-2
Health Professional from UNITED STATES reported TYSABRI problem on Feb 11, 2008. Male patient, 59 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: convulsion. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5638224-8
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 08, 2008. Female patient, 58 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: convulsion. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5638381-3
Physician from GERMANY reported TYSABRI problem on Feb 06, 2008. Male patient, 37 years of age, weighting 271.2 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: coronary artery disease, coronary artery occlusion, dilatation ventricular, disturbance in attention, mitral valve incompetence, myocardial infarction. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with DOXEPIN. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5639751-X
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 12, 2008. Female patient, 56 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient died on 02/08/2008.

Tysabri Side Effects Report #5639752-1
Health Professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Female patient, 41 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: abortion spontaneous, pregnancy. TYSABRI dosage: 300 MG;QM;IV. During the same period patient was treated with AVONEX. Patient recovered.

Tysabri Side Effects Report #5639955-6
TYSABRI problem was reported by a Consumer or non-health professional from GERMANY on Feb 12, 2008. Female patient, 30 years of age, was diagnosed with relapsing-remitting multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: blood fibrinogen increased, immune system disorder, opportunistic infection, pneumonia, staphylococcal sepsis, urge incontinence. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5639957-X
Physician from GERMANY reported TYSABRI problem on Feb 25, 2008. Male patient, 45 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: peritonsillar abscess, tonsillitis. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5639959-3
TYSABRI problem was reported by a Physician from BELGIUM on Feb 07, 2008. Male patient, 54 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, fatigue, gamma-glutamyltransferase increased, hepatic enzyme increased, urticaria. TYSABRI dosage: unknown. During the same period patient was treated with CARBAMAZEPINE. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5639960-X
Consumer or non-health professional from GREECE reported TYSABRI problem on Feb 11, 2008. Female patient, 50 years of age, weighting 149.9 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, autoimmune thyroiditis, blood bilirubin increased, dysphagia, gamma-glutamyltransferase increased, goitre, headache, muscle tightness. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with ACETAMINOPHEN, AMOXICILLIN. Patient recovered.

Tysabri Side Effects Report #5642250-2
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 19, 2008. Male patient, 45 years of age, weighting 189.6 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: central nervous system lymphoma, diffuse large b-cell lymphoma, enterococcal bacteraemia, urinary tract infection pseudomonal. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with ZOLOFT, PROTONIX, BACLOFEN, TYLENOL. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5642262-9
Health Professional from UNITED STATES reported TYSABRI problem on Feb 11, 2008. Female patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: asthenia, device failure, muscle spasticity, pain. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5642263-0
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 23, 2008. Female patient, 39 years of age, was diagnosed with muscle disorder and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: caesarean section, multiple sclerosis, pregnancy, premature labour. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with LEXAPRO. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5642264-2
Physician from UNITED STATES reported TYSABRI problem on Feb 11, 2008. Male patient, 52 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: no adverse event. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5642265-4
TYSABRI problem was reported by a Physician from UNITED STATES on Feb 11, 2008. Female patient, 48 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: brain operation. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5643144-9
Health Professional from SWITZERLAND reported TYSABRI problem on Feb 11, 2008. Female patient, 42 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: glossitis. TYSABRI dosage: unknown. Patient recovered.

Tysabri Side Effects Report #5643149-8
TYSABRI problem was reported by a Physician from AUSTRIA on Feb 14, 2008. Female patient, 24 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: acute tonsillitis, endocarditis, iron deficiency anaemia, mitral valve incompetence, pulmonary hypertension, pyrexia. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5643841-5
Health Professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Female patient, 59 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: breakthrough pain. TYSABRI dosage: 300 MG, QM, IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5643843-9
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 13, 2008. Female patient, 60 years of age, weighting 150.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: bone neoplasm malignant, costochondritis, road traffic accident, upper respiratory tract infection. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5643844-0
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Female patient, 59 years of age, weighting 150.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: diverticulitis, malaise, multiple sclerosis. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5643846-4
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 11, 2008. Female patient, 32 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: abortion spontaneous. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with BYETTA, METFORMIN, SYNTHROID, LISINOPRIL, BACLOFEN, HUMALOG REGULAR. Patient recovered.

Tysabri Side Effects Report #5643847-6
Health Professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Female patient, 59 years of age, weighting 130.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: progressive multiple sclerosis. TYSABRI dosage: 300 MG; Q; IV. Patient was hospitalized. Patient died on 02/01/2008.

Tysabri Side Effects Report #5644271-2
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 12, 2008. Female patient, 33 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: limb injury, road traffic accident. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5644272-4
Physician from UNITED STATES reported TYSABRI problem on Feb 14, 2008. Male patient, 54 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, platelet count decreased, white blood cell count increased. TYSABRI dosage: 300 MG;QM;IV. Patient recovered.

Tysabri Side Effects Report #5644273-6
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 19, 2008. Female patient, 59 years of age, weighting 175.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: colitis ischaemic, enterocolitis infectious. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5644274-8
Physician from UNITED STATES reported TYSABRI problem on Feb 15, 2008. Female patient, 29 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: cognitive disorder, multiple sclerosis relapse, pulmonary embolism, quadriplegia. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5644276-1
TYSABRI problem was reported by a Physician from UNITED STATES on Feb 15, 2008. Female patient, 46 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: eye irritation, headache, hypoaesthesia facial, paraesthesia oral, pruritus, rash macular. TYSABRI dosage: 63 ML;IV. Patient recovered.

Tysabri Side Effects Report #5644364-X
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Feb 15, 2008. Female patient, 45 years of age, weighting 143.3 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, cerebrovascular accident. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5644368-7
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 11, 2008. Male patient, 46 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: anaemia, angina pectoris, anxiety, atelectasis, atrial fibrillation, coronary artery disease, delirium, depression, electrocardiogram qt prolonged. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with BACLOFEN, TOPROL, PLAVIX, PREVACID, LISINOPRIL, OXYCODONE, ZOCOR, LASIX. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5644375-4
Health Professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Male patient, 44 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: fall, hip fracture, infusion site reaction, postoperative wound infection, staphylococcal infection, urticaria. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5644386-9
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 11, 2008. Female patient, 60 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: mental disorder. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5646315-0
Health Professional from FRANCE reported TYSABRI problem on Feb 14, 2008. Male patient, 37 years of age, was diagnosed with relapsing-remitting multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: blood bilirubin increased, diarrhoea, nausea, pancreatic disorder, renal colic, ulcer, vomiting. TYSABRI dosage: 300 MG; QM;. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5646734-2
TYSABRI problem was reported by a Physician from GERMANY on Feb 18, 2008. Female patient, 33 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: convulsion. TYSABRI dosage: 300 MG;QM;IV. During the same period patient was treated with PHENPROCOUMON, MIRTAZAPINE. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5647753-2
Health Professional from UNITED STATES reported TYSABRI problem on Feb 20, 2008. Female patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: osteonecrosis. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5647754-4
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 20, 2008. Male patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: convulsion, laceration. TYSABRI dosage: unknown. Patient recovered.

Tysabri Side Effects Report #5647759-3
Physician from UNITED STATES reported TYSABRI problem on Feb 20, 2008. Female patient, 43 years of age, weighting 151.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: fibromyalgia, idiopathic thrombocytopenic purpura, raynaud's phenomenon. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5647760-X
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 21, 2008. Female patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: cyst, memory impairment, parosmia. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5647761-1
Physician from UNITED STATES reported TYSABRI problem on Feb 19, 2008. Male patient, 31 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: asthenia, disease progression, impaired gastric emptying, multiple sclerosis, pneumonia. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5647770-2
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 19, 2008. Female patient, 30 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: staphylococcal infection. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5648177-4
Health Professional from UNITED STATES reported TYSABRI problem on Feb 13, 2008. Male patient, 60 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: colon cancer. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5648184-1
TYSABRI problem was reported by a Health Professional from UNITED STATES on Feb 21, 2008. Female patient, 45 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: uterine leiomyoma. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with AVONEX. Patient recovered.

Tysabri Side Effects Report #5648185-3
Health Professional from UNITED STATES reported TYSABRI problem on Feb 19, 2008. Female patient, 33 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: haemangioma. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5648188-9
TYSABRI problem was reported by a Physician from UNITED STATES on Feb 19, 2008. Male patient, 53 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: asthenia, blood urea increased, decubitus ulcer, depressed level of consciousness, escherichia infection, failure to thrive, hypotension, hypoxia, lethargy. TYSABRI dosage: 300 MG; QM; IV. Patient was hospitalized. Patient died on 05/22/2007.

Tysabri Side Effects Report #5583739-4
Physician from reported TYSABRI problem on Dec 21, 2007. Female patient, 45 years of age, weighting 92.59 lb, was diagnosed with multiple sclerosis relapse and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: demyelination, multiple sclerosis relapse, pulmonary embolism. TYSABRI dosage: unknown. During the same period patient was treated with ATENOLOL, OXYBUTININ, DIAZEPAM, LEVONORGESTREL, FELODIPINE. Patient died on 11/28/2007.

Tysabri Side Effects Report #5583740-0
TYSABRI problem was reported by a Consumer or non-health professional from IRELAND on Dec 21, 2007. Female patient, 42 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: autoimmune thrombocytopenia, contusion. TYSABRI dosage: 300 MG;QM;IV. Patient recovered.

Tysabri Side Effects Report #5583989-7
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Dec 21, 2007. Male patient, 63 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: lethargy, opportunistic infection, pneumonia. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with AVONEX. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5584033-8
TYSABRI problem was reported by a Health Professional from UNITED STATES on Dec 21, 2007. Female patient, 50 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal pain, dysphagia, neurogenic bladder. TYSABRI dosage: 300 MG;QM;IV. During the same period patient was treated with AVONEX. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5584036-3
Health Professional from UNITED STATES reported TYSABRI problem on Dec 21, 2007. Male patient, 40 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: thrombophlebitis. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5584038-7
TYSABRI problem was reported by a Health Professional from UNITED STATES on Dec 26, 2007. Female patient, 51 years of age, weighting 107.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: dysphagia, gastrooesophageal reflux disease, mycobacterium avium complex infection, opportunistic infection. TYSABRI dosage: 300 MG;QM;IV. During the same period patient was treated with ACTONEL, AMITRIPTYLINE, BACLOFEN, CITALOPRAM, KLONOPIN, NAMENDA, ROZEREM, SONATA. Patient recovered.

Tysabri Side Effects Report #5584040-5
Consumer or non-health professional from UNITED STATES reported TYSABRI problem on Dec 26, 2007. Female patient, 40 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: staphylococcal abscess. TYSABRI dosage: 300 MG;QM;IV. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5585974-8
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 20, 2007. Female patient, 40 years of age, weighting 140.0 lb, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: abscess, decubitus ulcer. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with BACLOFEN, EXCEDRIN, CYMBALTA, CALCIUM, IBUPROFEN, FAMOTIDINE, DITROPAN, PROPRANOLOL. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5585976-1
Health Professional from UNITED STATES reported TYSABRI problem on Dec 27, 2007. Female patient was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: neoplasm malignant. TYSABRI dosage: 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5585977-3
TYSABRI problem was reported by a Health Professional from UNITED STATES on Dec 27, 2007. Female patient, 47 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, hypertension, hypoaesthesia. TYSABRI dosage: 300 MG; QM; IV. During the same period patient was treated with AVONEX. Patient was hospitalized. Patient recovered.

Tysabri Side Effects Report #5585980-3
Health Professional from UNITED STATES reported TYSABRI problem on Dec 27, 2007. Female patient, 35 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: uterine leiomyoma. TYSABRI dosage: 300 MG; QM; IV, 300 MG; QM; IV. Patient recovered.

Tysabri Side Effects Report #5586065-2
TYSABRI problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 26, 2007. Female patient, 47 years of age, was diagnosed with multiple sclerosis and was treated with TYSABRI. After drug was administered, patient experienced the following problems/side effects: migraine. TYSABRI dosage: 300 MG;QM;IV. During the same period patient was treated with ESTRACE, LIPITOR, TOPAMAX, LUMIGAN, AMBIEN CR, ASPIRIN, LORTAB, PROTONIX. Patient was hospitalized. Patient recovered.

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