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Most Reported Valproic Side Effects

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Valproic Side Effects Summary

Valproic FDA adverse reports: 915. View All Valproic FDA Adverse Reports

Valproic FDA safety alerts: 2000 2002 2009

Reported deaths: 274

Reported hospitalizations: 312

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Valproic Side Effects Report: 7017622-4,Ovarian Granulosa-theca Cell Tumour, Peritonitis Sclerosing
on May 11, 2010 Female patient from UNITED STATES, , 14 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: ovarian granulosa-theca cell tumour, peritonitis sclerosing. Valproic dosage: Unk. During the same period patient was treated with PHENOBARBITAL, RANCEPINE, ZONISAMIDE, CARBAMAZEPINE. Patient was hospitalized.

Valproic Side Effects Report: 7016013-X,Abdominal Neoplasm, Cardiac Disorder, Cardiac Failure, Conduction Disorder, Drop Attacks, Heart Valve Replacement, Myoclonus, Oedema Peripheral, Platelet Count Decreased
on Sep 16, 2010 Male patient from UNITED KINGDOM, , 29 years of age, weighting 198.4 lb, was diagnosed with drop attacks, myoclonic epilepsy and was treated with Valproic. After Valproic was administered, patient had the following side effects: abdominal neoplasm, cardiac disorder, cardiac failure, conduction disorder, drop attacks, heart valve replacement, myoclonus, oedema peripheral, platelet count decreased. Valproic dosage: . During the same period patient was treated with VALPROIC ACID, CLOZAPINE. Patient was hospitalized.

Valproic Side Effects Report: 7016007-4,Osteoporosis
on Sep 20, 2010 Male patient from UNITED KINGDOM, , 29 years of age, was diagnosed with epilepsy (What is epilepsy?), bipolar i disorder and was treated with Valproic. After Valproic was administered, patient had the following side effects: osteoporosis (What is osteoporosis?). Valproic dosage: . During the same period patient was treated with VENLAFAXINE, LYSERGIDE, DIAMORPHINE, METHADONE, OLANZAPINE, QUETIAPINE.

Valproic Side Effects Report: 7011948-6,Blood Alkaline Phosphatase Increased
on Jun 09, 2010 Male patient from UNITED KINGDOM, , child 4 years of age, was treated with Valproic. After Valproic was administered, patient had the following side effects: blood alkaline phosphatase increased. Valproic dosage: .


Valproic Side Effects Report: 7010374-3,Accidental Overdose, Chorea
on Sep 09, 2010 Male patient from SINGAPORE, , 53 years of age, was diagnosed with overdose, convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: accidental overdose, chorea. Valproic dosage: . During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, VALPROIC ACID. Patient was hospitalized.

Valproic Side Effects Report: 7006187-9,Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Creatine Phosphokinase Increased, Blood Lactate Dehydrogenase Increased
on Sep 07, 2010 Male patient from TURKEY, , 26 years of age, was diagnosed with bipolar disorder (What is bipolar disorder?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: Valproic and alanine aminotransferase increased, Valproic and aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased. Valproic dosage: Dose For 4 Days Prior To Admission. During the same period patient was treated with QUETIAPINE, LITHIUM CARBONATE. Patient was hospitalized.

Valproic Side Effects Report: 7001519-X,Blood Creatine Phosphokinase Increased, Hepatic Enzyme Increased
on Sep 10, 2010 Male patient from TURKEY, , 26 years of age, was diagnosed with bipolar disorder (What is bipolar disorder?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: blood creatine phosphokinase increased, hepatic enzyme increased. Valproic dosage: . During the same period patient was treated with QUETIAPINE, LITHIUM. Patient was hospitalized.

Valproic Side Effects Report: 6992332-8,Cleft Lip And Palate
on Sep 06, 2010 Female patient from GERMANY, was diagnosed with bipolar disorder (What is bipolar disorder?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: cleft lip and palate (What is cleft lip and palate?). Valproic dosage: 600 Mg, Transplacental. During the same period patient was treated with SEROQUEL.

Valproic Side Effects Report: 6980343-8,Delusion, Malabsorption
on Aug 25, 2010 Female patient from CANADA, was diagnosed with affective disorder and was treated with Valproic. After Valproic was administered, patient had the following side effects: delusion, malabsorption. Valproic dosage: Po, Hs. During the same period patient was treated with HYDROCHLOROTHIAZIDE, ATORVASTATIN CALCIUM, RAMIPRIL, CALCIUM CARBONATE.


Valproic Side Effects Report: 6973208-9,Hepatic Adenoma
on Aug 31, 2010 Male patient from UNITED STATES, , 22 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: hepatic adenoma. Valproic dosage: . During the same period patient was treated with CARBAMAZEPINE, PHENOBARBITAL, ETHOSUXIMIDE.

Valproic Side Effects Report: 6964105-3,Jaundice, Vanishing Bile Duct Syndrome
on Aug 23, 2010 Female patient from TURKEY, , child 8 years of age, was diagnosed with convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: jaundice (What is jaundice?), vanishing bile duct syndrome. Valproic dosage: .

Valproic Side Effects Report: 6956046-2,Cholestasis, Hepatomegaly, Jaundice, Pruritus, Splenomegaly, Vanishing Bile Duct Syndrome, Xanthoma
on Aug 19, 2010 Female patient from TURKEY, , child 8 years of age, was diagnosed with convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: cholestasis, hepatomegaly, jaundice (What is jaundice?), pruritus, splenomegaly, vanishing bile duct syndrome, xanthoma. Valproic dosage: .

Valproic Side Effects Report: 6945561-3,Hepatic Enzyme Increased, Hepatotoxicity, Status Epilepticus
on Aug 19, 2010 Female patient from PHILIPPINES, , child 8 years of age, weighting 48.50 lb, was diagnosed with convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: hepatic enzyme increased, Valproic and hepatotoxicity, status epilepticus. Valproic dosage: . During the same period patient was treated with DEPACON. Patient died.

Valproic Side Effects Report: 6928991-5,Feeling Jittery, Hypoglycaemia
on Aug 07, 2010 Male patient from TURKEY, , weighting 5.95 lb, was treated with Valproic. After Valproic was administered, patient had the following side effects: feeling jittery, hypoglycaemia. Valproic dosage: . During the same period patient was treated with PHENYTOIN, OXYGEN, FLUID. Patient was hospitalized.


Valproic Side Effects Report: 6925800-5,Gastrointestinal Disorder, Product Substitution Issue
on Aug 13, 2010 Female patient from UNITED STATES, , child 8 years of age, weighting 114.4 lb, was diagnosed with convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: gastrointestinal disorder, product substitution issue. Valproic dosage: 375mg Twice Daily Po.

Valproic Side Effects Report: 6924218-9,Convulsion
on Aug 04, 2010 Male patient from GERMANY, , 17 years of age, was diagnosed with epilepsy (What is epilepsy?), hypothyroidism and was treated with Valproic. After Valproic was administered, patient had the following side effects: Valproic and convulsion. Valproic dosage: Up To 2500 Mg. During the same period patient was treated with LEVOTHYROXINE.

Valproic Side Effects Report: 6920934-3,Dysphemia
on Aug 06, 2010 Male patient from CANADA, , child 3 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: dysphemia. Valproic dosage: 3 In 1 D, 50 Mg/ml. During the same period patient was treated with VALPROIC ACID SYRUP.

Valproic Side Effects Report: 6906147-X,Dysphemia
on Jul 27, 2010 Male patient from CANADA, , child 3 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: dysphemia. Valproic dosage: 3 In 1 D, 50 Mg/ml. During the same period patient was treated with VALPROIC ACID SYRUP.

Valproic Side Effects Report: 6897887-X,Cerebral Palsy, Epilepsy, Fanconi Syndrome, Hypoxic-ischaemic Encephalopathy, Infantile Spasms, Large For Dates Baby, Neonatal Asphyxia, Oedema, Proteinuria
on Jul 19, 2010 Male patient from JAPAN, was diagnosed with tonic convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: cerebral palsy, epilepsy (What is epilepsy?), fanconi syndrome, hypoxic-ischaemic encephalopathy, infantile spasms, large for dates baby, neonatal asphyxia, Valproic and oedema, proteinuria. Valproic dosage: 25 Mg/kg, Qd. During the same period patient was treated with VITAMIN B6, PHENYTOIN, CLOBAZAM. Patient was hospitalized and became disabled.


Valproic Side Effects Report: 6879812-0,Hypocalcaemia
on Jul 14, 2010 Male patient from ITALY, , child 11 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: hypocalcaemia. Valproic dosage: . During the same period patient was treated with DEPAKENE, LAMICTAL. Patient was hospitalized.

Valproic Side Effects Report: 6870923-2,Fanconi Syndrome
on Jul 09, 2010 Female patient from JAPAN, was treated with Valproic. After Valproic was administered, patient had the following side effects: fanconi syndrome. Valproic dosage: Unk.

Valproic Side Effects Report: 6868892-4,Capsule Issue, Product Substitution Issue
on Jul 21, 2010 Male patient from UNITED STATES, , 37 years of age, weighting 100.3 lb, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: capsule issue, product substitution issue. Valproic dosage: Approximately 1 Year.

Valproic Side Effects Report: 6867492-X,Dysphemia
on Jul 15, 2010 Male patient from CANADA, , child 3 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: dysphemia. Valproic dosage: 3 In 1 D, 50 Mg/ml. During the same period patient was treated with VALPROIC ACID SYRUP.

Valproic Side Effects Report: 6862560-0,Amenorrhoea, Hirsutism, Polycystic Ovaries
on Jul 06, 2010 Female patient from TUNISIA, , 25 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: amenorrhoea, hirsutism, polycystic ovaries. Valproic dosage: 1500 Mg, Tid.


Valproic Side Effects Report: 6862431-X,Activities Of Daily Living Impaired, Bedridden, Cognitive Disorder, Dementia, Neuropsychiatric Lupus, Parkinsonism, Perseveration
on Jun 29, 2010 Female patient from NETHERLANDS, , 70 years of age, was diagnosed with epilepsy (What is epilepsy?), neuropsychiatric lupus and was treated with Valproic. After Valproic was administered, patient had the following side effects: activities of daily living impaired, bedridden, Valproic and cognitive disorder, dementia (What is dementia?), neuropsychiatric lupus, parkinsonism, perseveration. Valproic dosage: 500 Mg, Bid;. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, CYCLOPHOSPHAMIDE.

Valproic Side Effects Report: 6860694-8,Hypertension, Malignant Neoplasm Progression, Mental Status Changes, Pyrexia, Somnolence, Tachycardia, Unresponsive To Stimuli
on Jul 19, 2010 Female patient from UNITED STATES, , 30 years of age, weighting 110.2 lb, was diagnosed with breast cancer metastatic and was treated with Valproic. After Valproic was administered, patient had the following side effects: hypertension, malignant neoplasm progression, Valproic and mental status changes, Valproic and pyrexia, Valproic and somnolence, tachycardia, unresponsive to stimuli. Valproic dosage: 250 To 500mg Tid Days 1-28 Po, 1 Cycle. During the same period patient was treated with HYDRALAZINE, FLEXERIL. Patient was hospitalized.

Valproic Side Effects Report: 6847796-7,Agitation, Confusional State, Delusion, Disorientation, Gait Disturbance, Hallucinations, Mixed, Hyperammonaemic Encephalopathy
on Jun 29, 2010 Female patient from UNITED STATES, , 49 years of age, was treated with Valproic. After Valproic was administered, patient had the following side effects: agitation, Valproic and confusional state, delusion, disorientation, gait disturbance, hallucinations, mixed, hyperammonaemic encephalopathy. Valproic dosage: 750 M G;qd. During the same period patient was treated with BENZODIAZEPINE DERIATIVES, ETHANOL, LORAZEPAM, CITALOPRAM HYDROBROMIDE.

Valproic Side Effects Report: 6847756-6,Abdominal Distension, Dysarthria, Dyspepsia, Hyperammonaemic Encephalopathy, Oxygen Saturation Decreased, Refusal Of Treatment By Patient, Vomiting
on Jun 29, 2010 Male patient from UNITED STATES, , 47 years of age, was diagnosed with convulsion prophylaxis and was treated with Valproic. After Valproic was administered, patient had the following side effects: abdominal distension, dysarthria, dyspepsia, hyperammonaemic encephalopathy, oxygen saturation decreased, refusal of treatment by patient, Valproic and vomiting. Valproic dosage: 750 Mg;qd. During the same period patient was treated with BENZODIAZEPINE DERIVATIVES, BUPRENORPHINE, NALOXONE, LORAZEPAM, DIAMORPHINE, ALPRAZOLAM, BUPROPION HYDROCHLORIDE, OMEPRAZOLE.

Valproic Side Effects Report: 6847749-9,Dizziness, Hallucinations, Mixed, Hyperammonaemic Encephalopathy
on Jun 29, 2010 Female patient from UNITED STATES, , 51 years of age, was diagnosed with convulsion prophylaxis and was treated with Valproic. After Valproic was administered, patient had the following side effects: dizziness (What is dizziness?), hallucinations, mixed, hyperammonaemic encephalopathy. Valproic dosage: 750 Mg;qd. During the same period patient was treated with BENZODIAZEPINE DERIVATIVES, DIAMORPHINE, LORAZEPAM, SUPRENORPHINE HYDROCHLORIDE, NALOXONE, METHYLPHENIDATE, FLUOXETINE, ALPRAZOLAM.


Valproic Side Effects Report: 6837775-8,Blood Lactic Acid Increased, Blood Pyruvic Acid Increased, Csf Glucose Increased, Csf Protein Increased, Csf White Blood Cell Count Increased, Deafness Neurosensory, Diabetes Mellitus Inadequate Control, Epilepsy, Melas Syndrome
on Jun 29, 2010 Male patient from TAIWAN, PROVINCE OF CHINA, , 47 years of age, weighting 106.9 lb, was diagnosed with convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: blood lactic acid increased, blood pyruvic acid increased, csf glucose increased, csf protein increased, csf white blood cell count increased, deafness neurosensory, diabetes mellitus inadequate control, epilepsy (What is epilepsy?), melas syndrome. Valproic dosage: 1200 Mg, Single, 400 Mg, Q 6hr, Intravenous. During the same period patient was treated with CEFTRIAXONE, VANCOMYCIN.

Valproic Side Effects Report: 6830849-7,Hyperammonaemic Encephalopathy, Mediastinal Mass, Mental Status Changes, Metabolic Encephalopathy, Superior Vena Caval Occlusion, Tracheal Stenosis
on Jul 09, 2010 Male patient from UNITED STATES, , 56 years of age, was diagnosed with affective disorder and was treated with Valproic. After Valproic was administered, patient had the following side effects: hyperammonaemic encephalopathy, mediastinal mass, Valproic and mental status changes, metabolic encephalopathy, superior vena caval occlusion, tracheal stenosis. Valproic dosage: 1250 Mg Every Day Po. Patient died.

Valproic Side Effects Report: 6827380-1,Apallic Syndrome, Hepatic Failure, Hepatotoxicity, Psychomotor Skills Impaired
on Jul 02, 2010 Female patient from UNITED STATES, , child 9 years of age, was diagnosed with convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: apallic syndrome, hepatic failure, Valproic and hepatotoxicity, psychomotor skills impaired. Valproic dosage: Not Reported.

Valproic Side Effects Report: 6827309-6,Accommodation Disorder, Dysarthria, Tachycardia
on Jul 01, 2010 Female patient from GERMANY, , 40 years of age, weighting 198.4 lb, was treated with Valproic. After Valproic was administered, patient had the following side effects: accommodation disorder, dysarthria, tachycardia. Valproic dosage: . During the same period patient was treated with MELPERONE, DIAZEPAM.

Valproic Side Effects Report: 6827195-4,Caesarean Section
on Jul 01, 2010 Female patient from INDIA, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: caesarean section. Valproic dosage: 1200 Mg/day.


Valproic Side Effects Report: 6826719-0,Convulsion
on Jun 30, 2010 Male patient from UNITED STATES, , 49 years of age, was diagnosed with convulsion and was treated with Valproic. After Valproic was administered, patient had the following side effects: Valproic and convulsion. Valproic dosage: 7.5 Mg/kg, Unk. During the same period patient was treated with ERTAPENEM.

Valproic Side Effects Report: 6826711-6,Convulsion
on Jun 30, 2010 Male patient from UNITED STATES, , 28 years of age, was diagnosed with prophylaxis and was treated with Valproic. After Valproic was administered, patient had the following side effects: Valproic and convulsion. Valproic dosage: 25 Mg/kg, Unk. During the same period patient was treated with IMIPENEM.

Valproic Side Effects Report: 6816182-8,Ataxia, Cognitive Disorder, Demyelination, Dysgraphia, Fear, Feeling Abnormal, Feeling Cold, Impaired Driving Ability, Memory Impairment
on Jul 02, 2010 Male patient from UNITED STATES, , weighting 200.0 lb, was diagnosed with hemiparesis, migraine (What is migraine?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: ataxia (What is ataxia?), Valproic and cognitive disorder, demyelination, dysgraphia, fear, feeling abnormal, feeling cold, impaired driving ability, memory impairment. Valproic dosage: 500 Mg Twice A Day Po. During the same period patient was treated with VALPROIC ACID.

Valproic Side Effects Report: 6812206-2,Neutropenic Sepsis
on Jun 28, 2010 Male patient from UNITED KINGDOM, , 83 years of age, was diagnosed with epilepsy (What is epilepsy?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: neutropenic sepsis. Valproic dosage: . Patient was hospitalized.

Valproic Side Effects Report: 6785880-7,Grand Mal Convulsion
on Jun 21, 2010 Female patient from UNITED STATES, , 47 years of age, weighting 203.5 lb, was diagnosed with epilepsy (What is epilepsy?), hypothyroidism and was treated with Valproic. After Valproic was administered, patient had the following side effects: grand mal convulsion. Valproic dosage: 250mg Three Tablets Bid Po. During the same period patient was treated with VALPROIC ACID, KEPPRA.


Valproic Side Effects Report: 6785211-2,Mental Status Changes, Restlessness, Urinary Tract Infection
on Jun 22, 2010 Male patient from UNITED STATES, , 55 years of age, weighting 180.4 lb, was diagnosed with bipolar disorder (What is bipolar disorder?) and was treated with Valproic. After Valproic was administered, patient had the following side effects: Valproic and mental status changes, restlessness, urinary tract infection (What is urinary tract infection?). Valproic dosage: 1500 Qhs Po (chronic W/recent Increase). During the same period patient was treated with PERCOCET, METHADONE, LANTUS, NOVOLOG, NICODERM, TRAZODONE HYDROCHLORIDE, SENOKOT, MIRALEX. Patient was hospitalized.

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Valproic Side Effects
Valproic and Abnormal behaviour
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Valproic and Aspartate aminotransferase increased
Valproic and Brain oedema
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Valproic and Cardio-respiratory arrest
Valproic and Cognitive disorder
Valproic and Coma
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Valproic and Condition aggravated
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Valproic and Convulsion
Valproic and Depressed level of consciousness
Valproic and Disturbance in attention
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