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Review Valproic Safety Reports submitted to FDA

Total Valproic reports: 200.
Valproic FDA safety alerts: 2002 .
Reported deaths: 40    Reported hospitalizations: 74.
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FDA Reported Valproic Side Effects: poisoning, completed suicide, hyperammonaemia, status epilepticus, pleural effusion, pancreatitis acute, ammonia increased, convulsion, cardiac arrest, hepatotoxicity, aspartate aminotransferase increased.
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Valproic Side Effects Report #5397709-2
Consumer or non-health professional from UNITED KINGDOM reported VALPROIC problem on July 10, 2007. Female patient, 34 years of age, was diagnosed with bipolar disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: diabetic ketoacidosis, hypertriglyceridaemia, hyponatraemia, metabolic disorder, pancreatitis acute. VALPROIC dosage: unknown. During the same period patient was treated with QUETIAPINE FUMARATE. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5381919-4
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on July 02, 2007. Male patient, 64 years of age, was diagnosed with petit mal epilepsy, urinary tract infection, hypertension and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: cytolytic hepatitis. VALPROIC dosage: unknown. During the same period patient was treated with SULFONAMID ANTIBIOTIC, VALSARTAN. Patient recovered.

Valproic Side Effects Report #5382684-7
Physician from UNITED STATES reported VALPROIC problem on July 03, 2007. Male patient, child 6 years of age, weighting 47.40 lb, was diagnosed with epilepsy, grand mal convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour. VALPROIC dosage: 2CC OR 100 MG TID PO. During the same period patient was treated with VALPROIC ACID. Patient recovered.

Valproic Side Effects Report #5384969-7
VALPROIC problem was reported by a Physician from UNITED STATES on July 06, 2007. Male patient, 25 years of age, was diagnosed with cerebral sarcoidosis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: eosinophilia, pleural effusion. VALPROIC dosage: 250 MG/D. During the same period patient was treated with PREDNISONE, AZATHIOPRINE, QUETIAPINE FUMARATE, ESOMEPRAZOLE MAGNESIUM. Patient recovered.


Valproic Side Effects Report #5390935-8
Consumer or non-health professional from UNITED STATES reported VALPROIC problem on July 17, 2007. Male patient, 38 years of age, was diagnosed with convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pleural effusion. VALPROIC dosage: unknown. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5392114-7
VALPROIC problem was reported by a Pharmacist from UNITED STATES on July 18, 2007. Male patient, 49 years of age, weighting 130.0 lb, was diagnosed with bipolar disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: amino acid metabolism disorder, delirium, encephalopathy, hyperammonaemia. VALPROIC dosage: 500 MG AT 9 AM PO; 1000 MG AT 9 PM PO. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5392925-8
Physician from INDIA reported VALPROIC problem on July 06, 2007. Female patient, 25 years of age, was diagnosed with schizophrenia, paranoid type and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, blood pressure decreased, crepitations, electrocardiogram abnormal, electrocardiogram qt prolonged, glasgow coma scale abnormal, hypotonia, hypoxia, insomnia. VALPROIC dosage: unknown. During the same period patient was treated with RISPERIDONE, TRIHEXYPHENIDYL, CLONAZEPAM, ZIPRASIDONE. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5397656-6
VALPROIC problem was reported by a Pharmacist from UNITED STATES on July 23, 2007. Male patient, 24 years of age, weighting 179.0 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: ammonia increased. VALPROIC dosage: 1000 MG DAILY PO. Patient recovered.

Valproic Side Effects Report #5397707-9
Consumer or non-health professional from UNITED KINGDOM reported VALPROIC problem on July 09, 2007. Female patient, 41 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: suicide attempt. VALPROIC dosage: unknown. During the same period patient was treated with VENLAFAXIINE, OLANZAPINE. Patient was hospitalized. Patient recovered.


Valproic Side Effects Report #5397709-2
VALPROIC problem was reported by a Consumer or non-health professional from UNITED KINGDOM on July 10, 2007. Female patient, 34 years of age, was diagnosed with bipolar disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: diabetic ketoacidosis, hypertriglyceridaemia, hyponatraemia, metabolic disorder, pancreatitis acute. VALPROIC dosage: unknown. During the same period patient was treated with QUETIAPINE FUMARATE. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5758758-5
Consumer or non-health professional from NETHERLANDS reported VALPROIC problem on May 27, 2008. Female patient, 56 years of age, was diagnosed with temporal lobe epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: osteopenia. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5763757-3
VALPROIC problem was reported by a Consumer or non-health professional from UNITED STATES on June 06, 2008. Female patient was diagnosed with delirium and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: stevens-johnson syndrome. VALPROIC dosage: 250MG PO 2XD. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5767672-0
Consumer or non-health professional from FRANCE reported VALPROIC problem on June 04, 2008. Female patient, 62 years of age, was diagnosed with epilepsy, chronic obstructive pulmonary disease and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood lactate dehydrogenase increased, depressed level of consciousness, hyperammonaemia, metabolic encephalopathy, supraventricular tachycardia. VALPROIC dosage: unknown. During the same period patient was treated with SOTALOL, BACLOFEN, PAROXETINE, LACTULOSE, ASPIRIN, OMEPRAZOLE, PREDNISONE. Patient was hospitalized and became disabled. Patient recovered.

Valproic Side Effects Report #5768068-8
VALPROIC problem was reported by a Consumer or non-health professional from NETHERLANDS on June 03, 2008. Female patient, 51 years of age, weighting 163.1 lb, was diagnosed with convulsion, gallbladder cancer, prophylaxis of nausea and vomiting, cholinergic syndrome and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hepatotoxicity. VALPROIC dosage: unknown. During the same period patient was treated with IRINOTECAN, DEXAMETHASONE, GRANISETRON, ATROPINE SULPHATE. Patient was hospitalized. Patient recovered.


Valproic Side Effects Report #5778477-9
Pharmacist from UNITED STATES reported VALPROIC problem on June 17, 2008. Male patient, 57 years of age, weighting 167.6 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. VALPROIC dosage: 3000 MG DAILY PO. Patient recovered.

Valproic Side Effects Report #5794110-4
VALPROIC problem was reported by a Health Professional from FRANCE on June 18, 2008. Female patient, 76 years of age, was diagnosed with bipolar disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: accidental overdose, apnoea, confusional state, dehydration, escherichia infection, glasgow coma scale abnormal, hypotension, malaise. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, ASPIRIN, FUROSEMIDE, OLANZAPINE, RAMIPRIL, SIMVASTATIN. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5724749-3
Physician from AUSTRALIA reported VALPROIC problem on Apr 22, 2008. Female patient, 24 years of age, was diagnosed with schizophrenia and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, blood count abnormal, cognitive disorder, delusion, depression, malaise, neutrophil count decreased. VALPROIC dosage: unknown. During the same period patient was treated with CLOZARIL, RISPERIDONE, AMISULPRIDE, VALPROATE. Patient recovered.

Valproic Side Effects Report #5725694-X
VALPROIC problem was reported by a Consumer or non-health professional from BRAZIL on Apr 23, 2008. Male patient, 36 years of age, was diagnosed with bipolar disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: delirium. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, IAMOTRIGINE, CLONAZEPAM. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5726929-X
Physician from FRANCE reported VALPROIC problem on Apr 23, 2008. Female patient was diagnosed with epilepsy, prophylaxis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal labour, grand mal convulsion. VALPROIC dosage: 1500 MG DAILY. During the same period patient was treated with VALPROIC ACID, FOLIC ACID. Patient recovered.


Valproic Side Effects Report #5726953-7
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Apr 23, 2008. Male patient, weighting 6.40 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: anterior chamber cleavage syndrome, atrial septal defect, breast hypoplasia, cataract, cleft palate, congenital flat feet, congenital hand malformation, congenital heart valve disorder, congenital jaw malformation. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5727296-8
Physician from FRANCE reported VALPROIC problem on Apr 23, 2008. Male patient, weighting 8.16 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, autism spectrum disorder, cafe au lait spots, cognitive disorder, communication disorder, congenital hair disorder, congenital oral malformation, disturbance in attention, dysmorphism. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5727560-2
VALPROIC problem was reported by a Physician from FRANCE on Apr 23, 2008. Male patient, weighting 7.32 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: anisometropia, antisocial behaviour, astigmatism, balance disorder, congenital anomaly, congenital eye disorder, developmental coordination disorder, developmental delay, disturbance in attention. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5728182-X
Consumer or non-health professional from FRANCE reported VALPROIC problem on Apr 24, 2008. Male patient, weighting 7.54 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, aggression, antisocial behaviour, cognitive disorder, communication disorder, congenital nose malformation, coordination abnormal, developmental delay, disturbance in attention. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5731792-7
VALPROIC problem was reported by a Pharmacist from UNITED STATES on May 06, 2008. Male patient, 78 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. VALPROIC dosage: 250 MG BID PO. Patient recovered.

Valproic Side Effects Report #5731954-9
Physician from FRANCE reported VALPROIC problem on Apr 28, 2008. Female patient was diagnosed with epilepsy, vitamin supplementation and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: caesarean section, convulsion, loss of consciousness, road traffic accident. VALPROIC dosage: 1400MG DAILY, 600MG IN AM AND 800MG AT NIGHT. During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, FOLIC ACID. Patient recovered.

Valproic Side Effects Report #5732429-3
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Apr 28, 2008. Female patient, weighting 6.17 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, clinodactyly, cognitive disorder, congenital eyelid malformation, congenital hair disorder, congenital hand malformation, congenital nose malformation, dermatillomania, disturbance in attention. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5734048-1
Health Professional from FRANCE reported VALPROIC problem on Apr 30, 2008. Male patient, weighting 7.91 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, aggression, asocial behaviour, cognitive disorder, congenital foot malformation, congenital hand malformation, congenital hearing disorder, congenital nail disorder, congenital nose malformation. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5734116-4
VALPROIC problem was reported by a Physician from FRANCE on Apr 30, 2008. Female patient, weighting 8.49 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: chondrosis, conductive deafness, congenital hair disorder, congenital nose malformation, dysmorphism, ear infection, ear malformation, feeding disorder neonatal. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5734154-1
Physician from FRANCE reported VALPROIC problem on Apr 30, 2008. Female patient was diagnosed with epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: postpartum haemorrhage. VALPROIC dosage: 1600 MG, DAILY. During the same period patient was treated with CLOBAZAM, FOLIC ACID, CLOMIFENE. Patient recovered.

Valproic Side Effects Report #5734155-3
VALPROIC problem was reported by a Physician from FRANCE on Apr 30, 2008. Female patient, weighting 10.01 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, congenital hair disorder, congenital nose malformation, dacryostenosis congenital, dysmorphism, ear malformation, foetal anticonvulsant syndrome, foetal arrhythmia. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5734666-0
Physician from AUSTRALIA reported VALPROIC problem on May 01, 2008. Female patient, 24 years of age, was diagnosed with schizophrenia and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, blood count abnormal, cognitive disorder, delusion, depression, malaise, neutrophil count decreased, psychotic disorder. VALPROIC dosage: unknown. During the same period patient was treated with CLOZARIL, RISPERIDONE, AMISULPRIDE, VALPROATE. Patient recovered.

Valproic Side Effects Report #5735327-4
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on May 02, 2008. Female patient, 28 years of age, was diagnosed with epilepsy, convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abortion spontaneous, vomiting. VALPROIC dosage: unknown. During the same period patient was treated with PHENYTOIN. Patient recovered.

Valproic Side Effects Report #5735457-7
Physician from FRANCE reported VALPROIC problem on May 02, 2008. Male patient, weighting 8.73 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abdominal pain, abnormal behaviour, adenoidal hypertrophy, aggression, asocial behaviour, autism spectrum disorder, choking, communication disorder, congenital foot malformation. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5735685-0
VALPROIC problem was reported by a Physician from FRANCE on May 02, 2008. Male patient, weighting 62.17 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: apraxia, congenital nose malformation, developmental coordination disorder, dysmorphism, foetal anticonvulsant syndrome, hair disorder, hearing impaired, hyperacusis. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5735703-X
Physician from FRANCE reported VALPROIC problem on May 02, 2008. Female patient was diagnosed with epilepsy, convulsion prophylaxis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abortion spontaneous. VALPROIC dosage: 2000 MG, DAILY. During the same period patient was treated with VALPROIC ACID, LAMOTRIGINE. Patient recovered.

Valproic Side Effects Report #5735707-7
VALPROIC problem was reported by a Physician from FRANCE on May 02, 2008. Female patient, weighting 8.60 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, aggression, ankyloglossia congenital, antisocial behaviour, asthma, astigmatism, attention deficit/hyperactivity disorder, congenital nail disorder, congenital nose malformation. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5738110-9
Consumer or non-health professional from TUNISIA reported VALPROIC problem on May 06, 2008. Female patient was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: urticaria. VALPROIC dosage: unknown. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5738415-1
VALPROIC problem was reported by a Physician from FRANCE on May 14, 2008. Female patient, weighting 8.60 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, aggression, ankyloglossia congenital, antisocial behaviour, asthma, astigmatism, attention deficit/hyperactivity disorder, congenital nail disorder, congenital nose malformation. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5740180-9
Physician from FRANCE reported VALPROIC problem on May 07, 2008. Male patient, weighting 8.16 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, aggression, attention-seeking behaviour, congenital nail disorder, congenital nose malformation, congenital oral malformation, disturbance in attention, dysmorphism. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5740787-9
VALPROIC problem was reported by a Health Professional from FRANCE on May 09, 2008. Female patient, 36 years of age, was diagnosed with affective disorder, depression, acne, psychotic disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: leukopenia, neutropenia. VALPROIC dosage: 1500 MG DAILY. During the same period patient was treated with BECLOMETHASONE DIPROPIONATE, TRIHEXYPHENIDYL, CITALOPRAM HYDROBROMIDE, FISH OIL, MINOCYCLINE, PRIMULA SPP, QUETIAPINE FUMARATE. Patient recovered.

Valproic Side Effects Report #5741001-0
Consumer or non-health professional from FRANCE reported VALPROIC problem on May 09, 2008. Male patient, weighting 8.91 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, affect lability, alpha haemolytic streptococcal infection, c-reactive protein increased, cognitive disorder, communication disorder, congenital nose malformation, coordination abnormal, cyanosis. VALPROIC dosage: unknown. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5743045-1
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on May 09, 2008. Female patient was diagnosed with epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: epilepsy, grand mal convulsion. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, FOLIC ACID, LAMOTRIGINE. Patient recovered.

Valproic Side Effects Report #5743144-4
Physician from FRANCE reported VALPROIC problem on May 09, 2008. Female patient, weighting 7.58 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: aphasia, astigmatism, cognitive disorder, congenital hair disorder, congenital nose malformation, dacryostenosis acquired, dehydration, developmental delay. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5746108-X
VALPROIC problem was reported by a Physician from FRANCE on May 15, 2008. Male patient, weighting 7.14 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, aortogram abnormal, arthritis reactive, congenital aortic anomaly, congenital eye disorder, congenital hair disorder, congenital nose malformation, cough. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, LAMOTRIGINE. Patient recovered.

Valproic Side Effects Report #5752136-0
Physician from FRANCE reported VALPROIC problem on May 22, 2008. Male patient, weighting 9.01 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: acoustic stimulation tests abnormal, clinodactyly, congenital nose malformation, dysmorphism, foot deformity, gait disturbance, otitis media, speech disorder. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5753765-0
VALPROIC problem was reported by a Physician from FRANCE on May 21, 2008. Female patient was diagnosed with epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: grand mal convulsion. VALPROIC dosage: 800 MG DAILY. During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROATE, FOLIC ACID, CLOBAZAM. Patient recovered.

Valproic Side Effects Report #5754324-6
Physician from FRANCE reported VALPROIC problem on May 21, 2008. Male patient, weighting 6.64 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: acrochordon, anomaly of external ear congenital, ataxia, balance disorder, cardiomegaly, chalazion, congenital anomaly, congenital eyelid malformation, congenital hand malformation. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5759327-3
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on May 16, 2008. Male patient was diagnosed with epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: craniosynostosis, hypotelorism of orbit. VALPROIC dosage: 500 MG; TWICE A DAY TRANSPLACENTAL 500 MG; TRANSPLACENTAL; TWICE A DAY. During the same period patient was treated with LEVOTHYROXINE. Patient recovered.

Valproic Side Effects Report #5692074-5
Consumer or non-health professional from FRANCE reported VALPROIC problem on Mar 24, 2008. Female patient was diagnosed with antibiotic prophylaxis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: convulsion. VALPROIC dosage: unknown. During the same period patient was treated with MEROPENEM. Patient recovered.

Valproic Side Effects Report #5695011-2
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Mar 26, 2008. Female patient, 56 years of age, was diagnosed with epilepsy, diabetes mellitus, type 2 diabetes mellitus, hypercholesterolaemia, arthritis, weight decreased, obesity and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, epilepsy, feeling abnormal, glossodynia. VALPROIC dosage: unknown. During the same period patient was treated with INSULIN ASPART, INSULIN ASPART, METFORMIN, SIMVASTATIN, DICLOFENAC, RIMONABANT, FENOFIBRATE. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5708001-8
Health Professional from FRANCE reported VALPROIC problem on Apr 07, 2008. Female patient, 18 years of age, was diagnosed with affective disorder, autism, psychotic disorder, depression, sleep disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alopecia, emotional distress. VALPROIC dosage: unknown. During the same period patient was treated with ARIPIPRAZOLE, LOFEPRAMINE, MELATONIN. Patient recovered.

Valproic Side Effects Report #5724181-2
VALPROIC problem was reported by a Consumer or non-health professional from CANADA on Apr 24, 2008. Female patient, 13 years of age, was diagnosed with convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: aplasia pure red cell, megakaryocytes abnormal. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5350733-8
Consumer or non-health professional from FRANCE reported VALPROIC problem on May 31, 2007. Male patient, 81 years of age, was diagnosed with grand mal convulsion, epilepsy, hypertension and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: cognitive disorder, neurological symptom. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, NICARDIPINE HYDROCHLORIDE. Patient recovered.

Valproic Side Effects Report #5355361-6
VALPROIC problem was reported by a Physician from UNITED STATES on June 11, 2007. Female patient, 45 years of age, was diagnosed with convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abdominal pain, malaise, nausea, pancytopenia, vomiting. VALPROIC dosage: 750MG DAILY PO. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5359645-7
Consumer or non-health professional from UNITED STATES reported VALPROIC problem on June 08, 2007. Male patient, 25 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pleural effusion. VALPROIC dosage: unknown. During the same period patient was treated with PREDNISONE, AZATHIOPRINE, QUETIAPINE, ESOMEPRAZOLE MAGNESIUM. Patient recovered.

Valproic Side Effects Report #5363732-7
VALPROIC problem was reported by a Pharmacist from UNITED STATES on June 18, 2007. Female patient, 41 years of age, weighting 203.0 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alopecia. VALPROIC dosage: 1000 MG DAILY PO. Patient recovered.

Valproic Side Effects Report #5364291-5
Consumer or non-health professional from UNITED STATES reported VALPROIC problem on June 12, 2007. Male patient, 38 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pleural effusion. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5364292-7
VALPROIC problem was reported by a Consumer or non-health professional from UNITED STATES on June 12, 2007. Male patient, 42 years of age, was diagnosed with convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: eosinophilia, pleural effusion, pneumonia. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, CARBAMAZEPINE, FLUPHENAZINE, PROPRANOLOL, CHLORPROMAZINE, LORAZEPAM. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5364306-4
Consumer or non-health professional from UNITED STATES reported VALPROIC problem on June 12, 2007. Female patient, 19 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pleural effusion. VALPROIC dosage: unknown. During the same period patient was treated with OLANZAPINE, ANXIOLYTICS. Patient recovered.

Valproic Side Effects Report #5366957-X
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on June 12, 2007. Male patient, 34 years of age, was diagnosed with psychotic disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: eosinophilic pneumonia acute, nausea, pericardial effusion, pleural effusion, rash macular, vomiting. VALPROIC dosage: unknown. During the same period patient was treated with HALOPERIDOL, DIPHENHYDRAMINE, CLOZAPINE, BENZATROPINE, OLANZAPINE. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5367003-4
Pharmacist from UNITED STATES reported VALPROIC problem on June 19, 2007. Male patient, weighting 233.0 lb, was diagnosed with bipolar disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pancreatitis. VALPROIC dosage: 500 MG BID PO } 1 YEAR PTA. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5370821-X
VALPROIC problem was reported by a Consumer or non-health professional from UNITED STATES on June 20, 2007. Male patient, 25 years of age, was diagnosed with sarcoidosis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pleural effusion. VALPROIC dosage: unknown. During the same period patient was treated with PREDNISONE, AZATHIOPRINE, QUETIAPINE, ESOMEPRAZOLE MAGNESIUM. Patient recovered.

Valproic Side Effects Report #5372525-6
Consumer or non-health professional from FRANCE reported VALPROIC problem on June 20, 2007. Male patient, 64 years of age, was diagnosed with petit mal epilepsy, urinary tract infection, hypertension and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: cytolytic hepatitis. VALPROIC dosage: unknown. During the same period patient was treated with SULFONAMID ANTIBIOTIC, VALSARTAN. Patient recovered.

Valproic Side Effects Report #5376903-0
VALPROIC problem was reported by a Health Professional from UNITED STATES on June 28, 2007. Male patient was diagnosed with bipolar disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: nausea, vomiting. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5330281-1
Health Professional from FRANCE reported VALPROIC problem on May 11, 2007. Female patient, 33 years of age, was diagnosed with affective disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: idiopathic thrombocytopenic purpura, somnolence, tachycardia. VALPROIC dosage: unknown. During the same period patient was treated with AMISULPRIDE, CLOZAPINE, PAROXETINE, HYOSCINE HYT, SENNOSIDE A, ZAPONEX. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5335122-4
VALPROIC problem was reported by a Consumer or non-health professional from SWITZERLAND on May 18, 2007. Male patient, 13 years of age, was diagnosed with grand mal convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: extradural haematoma, platelet function test abnormal. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5335126-1
Consumer or non-health professional from SWITZERLAND reported VALPROIC problem on May 18, 2007. Male patient, child 4 years of age, was diagnosed with convulsion, encephalitis herpes and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, platelet function test abnormal. VALPROIC dosage: unknown. During the same period patient was treated with ACYCLOVIR. Patient died.

Valproic Side Effects Report #5286960-8
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Mar 27, 2007. Female patient, 23 years of age, was diagnosed with convulsion prophylaxis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hyperammonaemia, overdose, suicide attempt. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5287741-1
Consumer or non-health professional from UNITED STATES reported VALPROIC problem on Apr 02, 2007. Female patient, weighting 91.71 lb, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abdominal distension, atelectasis, blood calcium decreased, blood fibrinogen decreased, blood glucose increased, bowel sounds abnormal, collapse of lung, crepitations. VALPROIC dosage: 13950 MG. Patient was hospitalized. Patient died.

Valproic Side Effects Report #5287821-0
VALPROIC problem was reported by a Pharmacist from UNITED STATES on Apr 02, 2007. Male patient, weighting 115.3 lb, was diagnosed with bipolar disorder, mood altered, agitation and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: abdominal pain, colon cancer, constipation, faecaloma. VALPROIC dosage: 500MG BID (PO). During the same period patient was treated with VALPROIC ACID, QUETIAPINE FUMARATE, DOCUSATE, LACTASE, MINERAL OIL ENEMA, ASPIRIN, SIMVASTATIN, CARBAZEPINE. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5292241-9
Consumer or non-health professional from FRANCE reported VALPROIC problem on Apr 02, 2007. Male patient, child 11 years of age, was diagnosed with mania, aggression, agitation, psychotic disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hyperammonaemia, mania. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, RISPERDAL, LITHIUM CARBONATE, LITHIUM CARBONATE. Patient recovered.

Valproic Side Effects Report #5292242-0
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Apr 05, 2007. Male patient, child 11 years of age, was diagnosed with epilepsy, psychotic disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hyperammonaemia, mania. VALPROIC dosage: unknown. During the same period patient was treated with RISPERDAL, ETHOSUXIMIDE. Patient recovered.

Valproic Side Effects Report #5294733-5
Consumer or non-health professional from JAPAN reported VALPROIC problem on Apr 04, 2007. Male patient, 27 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: overdose. VALPROIC dosage: unknown. During the same period patient was treated with ZOTEPINE, RISPERDAL, CHLORPROMAZINE HYDROCHLORIDE, BETHANECHOL CHLORIDE, BROTIZOLAM, FLUNITRAZEPAM. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5295200-5
VALPROIC problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 03, 2007. Female patient, child 11 years of age, was diagnosed with petit mal epilepsy, migraine and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: convulsion. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, TOPIRAMATE. Patient recovered.

Valproic Side Effects Report #5298215-6
Consumer or non-health professional from FRANCE reported VALPROIC problem on Apr 06, 2007. Female patient, 34 years of age, was diagnosed with affective disorder, schizophrenia and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: idiopathic thrombocytopenic purpura, somnolence, tachycardia. VALPROIC dosage: unknown. During the same period patient was treated with PAROXETINE, CLOZAPINE, AMISULPRIDE, HYOSCINE HYT, SENNA GLYCOSIDES. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5299395-9
VALPROIC problem was reported by a Physician from UNITED STATES on Apr 11, 2007. Male patient, child 7 years of age, weighting 55.78 lb, was diagnosed with attention deficit/hyperactivity disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: erection increased, rash. VALPROIC dosage: 250MG QD IN AM PO. Patient recovered.

Valproic Side Effects Report #5303615-1
Consumer or non-health professional from FRANCE reported VALPROIC problem on Apr 11, 2007. Male patient, 38 years of age, was diagnosed with epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: status epilepticus. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5309027-9
VALPROIC problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 18, 2007. Female patient, child 5 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: acute hepatic failure, brain oedema, convulsion, hepatic necrosis, influenza like illness, pyrexia. VALPROIC dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, BROMIDE. Patient died on 01/01/2000.

Valproic Side Effects Report #5309028-0
Consumer or non-health professional from UNITED STATES reported VALPROIC problem on Apr 18, 2007. Female patient, child 5 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: acute hepatic failure, brain oedema, convulsion, influenza like illness. VALPROIC dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, BROMIDE. Patient died.

Valproic Side Effects Report #5310510-0
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Apr 20, 2007. Male patient, 38 years of age, was diagnosed with epilepsy, convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: status epilepticus. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, CARBAMAZEPINE. Patient recovered.

Valproic Side Effects Report #5345151-2
Consumer or non-health professional from UNITED STATES reported VALPROIC problem on Jan 11, 2007. Female patient, 51 years of age, was diagnosed with convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: ammonia increased, confusional state. VALPROIC dosage: unknown. During the same period patient was treated with FLUOXETINE, SINEMET, NAPROXEN, OMEPRAZOLE, TOPIRAMATE, TRAZODONE, LORAZEPAM, PHENYTOIN. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5255897-2
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, 28 years of age, was diagnosed with myoclonic epilepsy and ragged-red fibers and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hepatic failure, hypoglycaemia. VALPROIC dosage: unknown. Patient died.

Valproic Side Effects Report #5255898-4
Consumer or non-health professional from FRANCE reported VALPROIC problem on Feb 23, 2007. Male patient, 18 years of age, was diagnosed with neonatal asphyxia and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatotoxicity, rhabdomyolysis. VALPROIC dosage: unknown. During the same period patient was treated with PHENOBARBITAL. Patient recovered.

Valproic Side Effects Report #5255900-X
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, child 10 years of age, was diagnosed with fragile x syndrome and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic encephalopathy, hepatotoxicity, renal failure. VALPROIC dosage: unknown. During the same period patient was treated with TOPIRAMATE. Patient recovered.

Valproic Side Effects Report #5255902-3
Consumer or non-health professional from FRANCE reported VALPROIC problem on Feb 23, 2007. Female patient, child 9. years of age, was diagnosed with dysmorphism and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: ammonia increased, convulsion, hepatotoxicity. VALPROIC dosage: unknown. During the same period patient was treated with PHENOBARBITAL. Patient recovered.

Valproic Side Effects Report #5255903-5
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, 25 years of age, was diagnosed with epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, cerebral infarction, gamma-glutamyltransferase increased, hepatotoxicity, rhabdomyolysis. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5255904-7
Consumer or non-health professional from FRANCE reported VALPROIC problem on Feb 23, 2007. Female patient, 17 years of age, was diagnosed with myoclonic epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatotoxicity, jaundice. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5255906-0
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Male patient, child 12 years of age, was diagnosed with epilepsy, status epilepticus and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hepatic failure, multi-organ failure, rhabdomyolysis. VALPROIC dosage: unknown. During the same period patient was treated with PROPOFOL. Patient died.

Valproic Side Effects Report #5255907-2
Consumer or non-health professional from FRANCE reported VALPROIC problem on Feb 23, 2007. Male patient, 23 years of age, was diagnosed with encephalitis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hepatic failure, liver abscess. VALPROIC dosage: unknown. During the same period patient was treated with CARBAMAZEPINE. Patient died.

Valproic Side Effects Report #5255908-4
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Female patient, child 7. years of age, was diagnosed with hydrocephalus and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatotoxicity, renal failure. VALPROIC dosage: unknown. During the same period patient was treated with ETHOSUXIMIDE, VIGABATRIN. Patient recovered.

Valproic Side Effects Report #5255909-6
Consumer or non-health professional from FRANCE reported VALPROIC problem on Feb 23, 2007. Female patient, child 4 years of age, was diagnosed with amaurotic familial idiocy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, hepatotoxicity, jaundice. VALPROIC dosage: unknown. During the same period patient was treated with ETHOSUXIMIDE. Patient recovered.

Valproic Side Effects Report #5255910-2
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2007. Male patient, child 6 years of age, was diagnosed with myoclonic epilepsy, status epilepticus and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, hepatic failure. VALPROIC dosage: unknown. During the same period patient was treated with PROPOFOL. Patient died.

Valproic Side Effects Report #5261140-0
Consumer or non-health professional from JAPAN reported VALPROIC problem on Feb 28, 2007. Male patient, 27 years of age, was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: overdose. VALPROIC dosage: unknown. During the same period patient was treated with ZOTEPINE, RISPERIDONE, CHLORPROMAZINE HYDROCHLORIDE, BETHANECHOL CHLORIDE, BROTIZOLAM, FLUNITRAZEPAM. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5267773-X
VALPROIC problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 13, 2007. Female patient, 28 years of age, was diagnosed with convulsion and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: status epilepticus. VALPROIC dosage: unknown. During the same period patient was treated with TIAGABINE. Patient recovered.

Valproic Side Effects Report #5270362-4
Consumer or non-health professional from FRANCE reported VALPROIC problem on Mar 12, 2007. Male patient, child 11 years of age, was diagnosed with epilepsy, psychotic disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hyperammonaemia, mania. VALPROIC dosage: unknown. During the same period patient was treated with RISPERIDONE, ETHOSUXIMIDE. Patient recovered.

Valproic Side Effects Report #5270368-5
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Mar 12, 2007. Male patient, child 11 years of age, was diagnosed with mania, aggression, agitation, psychotic disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: hyperammonaemia, mania. VALPROIC dosage: unknown. During the same period patient was treated with VALPROIC ACID, VALPROIC ACID, RISPERIDONE, LITHIUM CARBONATE, LITHIUM CARBONATE. Patient recovered.

Valproic Side Effects Report #5271468-6
Health Professional from FRANCE reported VALPROIC problem on Mar 13, 2007. Female patient, 33 years of age, was diagnosed with affective disorder and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: idiopathic thrombocytopenic purpura, somnolence, tachycardia. VALPROIC dosage: unknown. During the same period patient was treated with AMISULPRIDE, CLOZAPINE, PAROXETINE, HYOSCINE HYT, SENNOSIDE A, ZAPONEX. Patient was hospitalized. Patient recovered.

Valproic Side Effects Report #5280717-X
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Mar 19, 2007. Male patient, child 12 years of age, was diagnosed with temporal lobe epilepsy and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pancreatic necrosis, pancreatitis acute. VALPROIC dosage: unknown. Patient recovered.

Valproic Side Effects Report #5280718-1
Consumer or non-health professional from FRANCE reported VALPROIC problem on Mar 19, 2007. Male patient, child 11 years of age, was diagnosed with trisomy 13, convulsion prophylaxis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, pancreatitis acute. VALPROIC dosage: unknown. During the same period patient was treated with PHENOBARBITAL. Patient recovered.

Valproic Side Effects Report #5280719-3
VALPROIC problem was reported by a Consumer or non-health professional from FRANCE on Mar 19, 2007. Male patient, child 4 years of age, was diagnosed with myoclonic epilepsy, convulsion prophylaxis and was treated with VALPROIC. After drug was administered, patient experienced the following problems/side effects: pancreatic insufficiency, pancreatitis acute. VALPROIC dosage: unknown. During the same period patient was treated with SULTIAME, CLARITHROMYCIN. Patient recovered.

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