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Velcade Side Effects

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Common Velcade Side Effects


The most commonly reported Velcade side effects (click to view or check a box to report):

Diarrhoea (693)
Disease Progression (693)
Platelet Count Decreased (506)
Asthenia (453)
Neuropathy Peripheral (444)
Anaemia (436)
Pyrexia (432)
Pneumonia (397)
Dyspnoea (379)
Thrombocytopenia (366)
Hypotension (358)
Multiple Myeloma (339)
Nausea (328)
Fatigue (317)
Dehydration (315)
Constipation (313)
Haemoglobin Decreased (301)
Blood Lactate Dehydrogenase Increased (271)
Atrial Fibrillation (271)
Malignant Neoplasm Progression (230)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Velcade Side Effects Reported to FDA



Velcade Side Effect Report#9999028
Neuropathy Peripheral
This is a report of a 65-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: plasma cell myeloma, who was treated with Velcade (dosage: NA, start time:
Feb 01, 2013), combined with:
  • Revlimid
  • Dexamethasone
and developed a serious reaction and side effect(s): Neuropathy Peripheral after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Velcade treatment in male patients, resulting in Neuropathy Peripheral side effect.
Velcade Side Effect Report#9996622
This report suggests a potential Velcade Death side effect(s) that can have serious consequences. A 62-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: plasma cell myeloma and used Velcade (dosage: 2.5 Mg) starting NS. After starting Velcade the patient began experiencing various side effects, including:Additional drugs used concurrently: NA. Although Velcade demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Death, may still occur.
Velcade Side Effect Report#9980724
Leukopenia, Platelet Count Decreased
This Leukopenia problem was reported by a health professional from US. A 65-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: plasma cell myeloma. On NS this consumer started treatment with Velcade (dosage: NA). The following drugs were being taken at the same time: NA. When using Velcade, the patient experienced the following unwanted symptoms/side effects: Leukopenia, Platelet Count DecreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Leukopenia, may become evident only after a product is in use by the general population.
Velcade Side Effect Report#9980696
Nausea, Diarrhoea, Fatigue
This Nausea side effect was reported by a health professional from US. A 64-year-old female patient (weight:NA) experienced the following symptoms/conditions: plasma cell myeloma.The patient was prescribed Velcade (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Velcade the consumer reported adverse symptoms, such as: Nausea, Diarrhoea, FatigueThese side effects may potentially be related to Velcade.
Velcade Side Effect Report#9980399
Neuropathy Peripheral, Fatigue, Pneumonia, Diarrhoea
This is a report of a 58-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: plasma cell myeloma, who was treated with Velcade (dosage: NA, start time: 201309), combined with:
  • Prednisone
  • Revlimid
  • Dexamethasone
and developed a serious reaction and side effect(s): Neuropathy Peripheral, Fatigue, Pneumonia, Diarrhoea after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Velcade treatment in male patients, resulting in Neuropathy Peripheral side effect.
Velcade Side Effect Report#9980381
Protein Total Increased
This report suggests a potential Velcade Protein Total Increased side effect(s) that can have serious consequences. A 39-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: plasma cell myeloma and used Velcade (dosage: NA) starting 201310. After starting Velcade the patient began experiencing various side effects, including: Protein Total IncreasedAdditional drugs used concurrently:
  • Revlimid
Although Velcade demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Protein Total Increased, may still occur.
Velcade Side Effect Report#9980369
Neuropathy Peripheral, Hypoaesthesia, Walking Aid User, Herpes Zoster
This Neuropathy Peripheral problem was reported by a health professional from US. A 65-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: plasma cell myeloma. On 200905 this consumer started treatment with Velcade (dosage: NA). The following drugs were being taken at the same time:
  • Doxil
  • Dexamethasone
When using Velcade, the patient experienced the following unwanted symptoms/side effects: Neuropathy Peripheral, Hypoaesthesia, Walking Aid User, Herpes ZosterAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Neuropathy Peripheral, may become evident only after a product is in use by the general population.
Velcade Side Effect Report#9969565
Pain, Chills, Dizziness, Abdominal Distension, Gastric Disorder
This Pain side effect was reported by a consumer or non-health professional from US. A 73-year-old female patient (weight:NA) experienced the following symptoms/conditions: plasma cell myeloma.The patient was prescribed Velcade (drug dosage: NA), which was initiated on 201306. Concurrently used drugs:
  • Dexamethasone
.After starting to take Velcade the consumer reported adverse symptoms, such as: Pain, Chills, Dizziness, Abdominal Distension, Gastric DisorderThese side effects may potentially be related to Velcade.
Velcade Side Effect Report#9964427
Diabetes Mellitus Inadequate Control, Hyperglycaemia, Pneumonia
This is a report of a 86-year-old patient (weight: NA) from US, suffering from the following health symptoms/conditions: plasma cell myeloma, who was treated with Velcade (dosage: 1.3 Mg/m2, 1/week, start time:
Oct 07, 2013), combined with:
  • Dexamethasone (20 Mg, Unk)
and developed a serious reaction and side effect(s): Diabetes Mellitus Inadequate Control, Hyperglycaemia, Pneumonia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Velcade treatment in patients, resulting in Diabetes Mellitus Inadequate Control side effect.
Velcade Side Effect Report#9960085
Diarrhoea, Neuropathy Peripheral, Fatigue, Constipation, Rash
This report suggests a potential Velcade Diarrhoea side effect(s) that can have serious consequences. A 72-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: plasma cell myeloma and used Velcade (dosage: NA) starting NS. After starting Velcade the patient began experiencing various side effects, including: Diarrhoea, Neuropathy Peripheral, Fatigue, Constipation, RashAdditional drugs used concurrently: NA. Although Velcade demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Diarrhoea, may still occur.
Velcade Side Effect Report#9960075
Fatigue, Neuropathy Peripheral, Injection Site Irritation, Injection Site Erythema, Injection Site Pain
This Fatigue problem was reported by a health professional from US. A 43-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: plasma cell myeloma. On
Oct 05, 2011 this consumer started treatment with Velcade (dosage: NA). The following drugs were being taken at the same time:
  • Dexamethasone
When using Velcade, the patient experienced the following unwanted symptoms/side effects: Fatigue, Neuropathy Peripheral, Injection Site Irritation, Injection Site Erythema, Injection Site PainAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Velcade Side Effect Report#9954273
Weight Decreased, Nausea
This Weight Decreased side effect was reported by a health professional from US. A 72-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Velcade (drug dosage: Unk), which was initiated on
Feb 01, 2014. Concurrently used drugs:
  • Revlimid (25 Mg, For 21 Days In 28 Days Cycle)
.After starting to take Velcade the consumer reported adverse symptoms, such as: Weight Decreased, NauseaThese side effects may potentially be related to Velcade.
Velcade Side Effect Report#9943544
Abdominal Abscess, Clostridium Bacteraemia, Large Intestine Perforation, Peritonitis, Small Intestinal Obstruction, Septic Shock, Mantle Cell Lymphoma Refractory
This is a report of a 57-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: mantle cell lymphoma, who was treated with Velcade (dosage: Unk, start time: NS), combined with:
  • Bendamustine
  • Rituximab
  • Cyclophosphamide
  • Doxorubicin
  • Vincristine
  • Prednisone
and developed a serious reaction and side effect(s): Abdominal Abscess, Clostridium Bacteraemia, Large Intestine Perforation, Peritonitis, Small Intestinal Obstruction, Septic Shock, Mantle Cell Lymphoma Refractory after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Velcade treatment in male patients, resulting in Abdominal Abscess side effect.
Velcade Side Effect Report#9943467
This report suggests a potential Velcade Death side effect(s) that can have serious consequences. A 89-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: plasma cell myeloma and used Velcade (dosage: 1.3 Mg/m2, Unk) starting
Jan 22, 2013. After starting Velcade the patient began experiencing various side effects, including:Additional drugs used concurrently: NA. Although Velcade demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Death, may still occur.
Velcade Side Effect Report#9932811
Neuropathy Peripheral
This Neuropathy Peripheral problem was reported by a consumer or non-health professional from US. A 69-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: plasma cell myeloma. On NS this consumer started treatment with Velcade (dosage: NA). The following drugs were being taken at the same time: NA. When using Velcade, the patient experienced the following unwanted symptoms/side effects: Neuropathy PeripheralAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Neuropathy Peripheral, may become evident only after a product is in use by the general population.
Velcade Side Effect Report#9928435
Fatigue
This Fatigue side effect was reported by a health professional from US. A 56-year-old female patient (weight:NA) experienced the following symptoms/conditions: plasma cell myeloma.The patient was prescribed Velcade (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Velcade the consumer reported adverse symptoms, such as: FatigueThese side effects may potentially be related to Velcade.
Velcade Side Effect Report#9928428
Neuropathy Peripheral, Fatigue, Neuralgia, Constipation
This is a report of a 70-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: plasma cell myeloma, who was treated with Velcade (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Neuropathy Peripheral, Fatigue, Neuralgia, Constipation after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Velcade treatment in female patients, resulting in Neuropathy Peripheral side effect.
Velcade Side Effect Report#9928425
Neutropenia, Neuropathy Peripheral, Fatigue, Leukopenia
This report suggests a potential Velcade Neutropenia side effect(s) that can have serious consequences. A 66-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: plasma cell myeloma and used Velcade (dosage: NA) starting 200807. After starting Velcade the patient began experiencing various side effects, including: Neutropenia, Neuropathy Peripheral, Fatigue, LeukopeniaAdditional drugs used concurrently: NA. Although Velcade demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neutropenia, may still occur.
Velcade Side Effect Report#9925504
Fatigue, Injection Site Reaction, Discomfort
This Fatigue problem was reported by a consumer or non-health professional from US. A 53-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: plasma cell myeloma. On NS this consumer started treatment with Velcade (dosage: NA). The following drugs were being taken at the same time: NA. When using Velcade, the patient experienced the following unwanted symptoms/side effects: Fatigue, Injection Site Reaction, DiscomfortAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Velcade Side Effect Report#9925426
Diarrhoea, Fatigue, Constipation
This Diarrhoea side effect was reported by a consumer or non-health professional from US. A 54-year-old female patient (weight:NA) experienced the following symptoms/conditions: plasma cell myeloma.The patient was prescribed Velcade (drug dosage: NA), which was initiated on 201004. Concurrently used drugs:
  • Revlimid
  • Dexamethasone
.After starting to take Velcade the consumer reported adverse symptoms, such as: Diarrhoea, Fatigue, ConstipationThese side effects may potentially be related to Velcade.
Velcade Side Effect Report#9925411
Thrombocytopenia, Neuropathy Peripheral, Anaemia
This is a report of a 53-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: plasma cell myeloma, who was treated with Velcade (dosage: NA, start time: 200810), combined with:
  • Dexamethasone
and developed a serious reaction and side effect(s): Thrombocytopenia, Neuropathy Peripheral, Anaemia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Velcade treatment in female patients, resulting in Thrombocytopenia side effect.
Velcade Side Effect Report#9925409
Nausea, Diarrhoea, Fatigue, Leukopenia, Vomiting
This report suggests a potential Velcade Nausea side effect(s) that can have serious consequences. A 56-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: plasma cell myeloma and used Velcade (dosage: NA) starting NS. After starting Velcade the patient began experiencing various side effects, including: Nausea, Diarrhoea, Fatigue, Leukopenia, VomitingAdditional drugs used concurrently: NA. Although Velcade demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nausea, may still occur.
Velcade Side Effect Report#9924509
Fatigue, Memory Impairment, Hypoaesthesia, Feeling Abnormal
This Fatigue problem was reported by a health professional from US. A 46-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: plasma cell myeloma. On 201201 this consumer started treatment with Velcade (dosage: NA). The following drugs were being taken at the same time:
  • Revlimid
When using Velcade, the patient experienced the following unwanted symptoms/side effects: Fatigue, Memory Impairment, Hypoaesthesia, Feeling AbnormalAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Velcade Side Effect Report#9923129
Myelodysplastic Syndrome
This Myelodysplastic Syndrome side effect was reported by a health professional from US. A 66-year-old male patient (weight:NA) experienced the following symptoms/conditions: plasma cell myeloma.The patient was prescribed Velcade (drug dosage: Unk), which was initiated on
Jun 06, 2013. Concurrently used drugs:
  • Lenalidomide (Unk)
  • Lenalidomide (Unk)
  • Dexamethasone (Unk)
  • Carvedilol (12.5 Mg, Bid)
  • Cipro /00697201/ (500 Mg, Bid)
  • Klor-con (40 Meq, Bid)
  • Mag-ox (400 Mg, Tid)
  • Augmentin (125 Mg, Bid For 10 Day)
.After starting to take Velcade the consumer reported adverse symptoms, such as: Myelodysplastic SyndromeThese side effects may potentially be related to Velcade.
Velcade Side Effect Report#9922487
Liver Function Test Abnormal
This is a report of a 79-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: plasma cell myeloma, who was treated with Velcade (dosage: 1.2 Mg/m2, Day 1, 4, 8, 11 Every 21 Days, start time:
Jun 11, 2013), combined with:
  • Dexamethasone (20 Mg, Days 1, 2, 4, 5, 8, 9, 11, 12, Every 21 Days)
and developed a serious reaction and side effect(s): Liver Function Test Abnormal after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Velcade treatment in male patients, resulting in Death side effect. The patient was hospitalized.


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The appearance of Velcade on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Velcade Side Effects for Women?

Women Side EffectsReports
Diarrhoea 275
Disease Progression 273
Platelet Count Decreased 205
Anaemia 189
Asthenia 186
Nausea 185
Pyrexia 184
Neuropathy Peripheral 175
Thrombocytopenia 168
Dyspnoea 156

What are common Velcade Side Effects for Men?

Men Side EffectsReports
Disease Progression 408
Diarrhoea 396
Platelet Count Decreased 296
Neuropathy Peripheral 263
Asthenia 252
Pneumonia 247
Anaemia 244
Pyrexia 241
Dyspnoea 220
Hypotension 211

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Velcade reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Velcade Side Effects

    Did You Have a Velcade Side Effect?

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    Yes, Moderate
    Yes, Minor
    No

    How Effective is Velcade for You?

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    Velcade Safety Alerts, Active Ingredients, Usage Information

    Velcade Dosage, Warnings, Usage.

    Side Effects reported to FDA: 7752

    Velcade safety alerts: 2010

    Reported deaths: 2657

    Reported hospitalizations: 4992

    Velcade (bortezomib): Starting Dose Adjustments for Patients with Hepatic Impairment

    Audience: Hematology, Oncology healthcare professionals

    [Posted 01/26/2010] Millennium Pharmaceuticals and FDA notified healthcare professionals about revisions to the Prescribing Information for Velcade, section 2.5, pertaining to patients with hepatic impairment at the start of Velcade therapy. The changes also include new safety information on dose adjustment for patients with moderate to severe hepatic impairment in label Section 5.11, stating: "Bortezomib is metabolized by liver enzymes. Bortezomib exposure is increased in patients with moderate or severe hepatic impairment; these patients should be treated with VELCADE at reduced starting doses and closely monitored for toxicities."

    Velcade is indicated for the treatment of patients with multiple myeloma. Velcade also is indicated for the treatment of patients with mantle cell lymphoma who have received at least one prior therapy.

    [01/04/2010 - Dear Healthcare Professional Letter - Millennium Pharmaceuticals]
    [12/30/2009 - Prescribing Information - Millennium Pharmaceuticals]

     

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