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Total Velcade reports: 1595.Velcade FDA safety alerts: No.
Reported deaths: 428 Reported hospitalizations: 996.
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FDA Reported Velcade Side Effects: diarrhoea, thrombocytopenia, pyrexia, disease progression, asthenia, neuropathy peripheral, platelet count decreased, hypotension, blood lactate dehydrogenase increased, atrial fibrillation, nausea.
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Showing 1-100 of 1595 Next >
Velcade Side Effects Report #5226888-2Physician from JAPAN reported VELCADE problem on Jan 15, 2007. Male patient, 72 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure, cardiovascular insufficiency, cerebral infarction, condition aggravated, dehydration, depressed level of consciousness, disease recurrence, hypercalcaemia, interstitial lung disease. VELCADE dosage: 1.30 MG/M2,. During the same period patient was treated with DEXAMETHASONE, ISOSORBIDE DINITRATE, FAMOTIDINE, BAKTAR, ALLOPURINOL, BICARBONATE, LASIX. Patient died on 01/14/2007.
Velcade Side Effects Report #5226890-0
VELCADE problem was reported by a Physician from JAPAN on Jan 18, 2007. Male patient, 71 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: basophil count decreased, blood alkaline phosphatase decreased, blood lactate dehydrogenase increased, blood urea increased, blood uric acid increased, c-reactive protein decreased, computerised tomogram thorax, febrile neutropenia, fungal dna test positive. VELCADE dosage: 1.40 MG, INTRAVENOUS. During the same period patient was treated with ZOMETA, BICARBONATE, NEUTROGIN, AMIKACIN SULPHATE, LASIX, VORICONAZOLE, RABEPRAZOLE, ENALAPRIL MALEATE. Patient recovered.
Velcade Side Effects Report #5227115-2
Physician from UNITED STATES reported VELCADE problem on Jan 19, 2007. Male patient, 58 years of age, weighting 168.9 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bundle branch block left, dehydration, diarrhoea, dizziness, hypocalcaemia, loss of consciousness, syncope vasovagal. VELCADE dosage: 1.30 MG/M2 IV BOLUS. During the same period patient was treated with DEXAMETHASONE, PREVACID, OXYCONTIN, LASIX, FLOMAX, ALDACTONE, ALLEGRA, FLONASE. Patient was hospitalized and became disabled. Patient recovered.
Velcade Side Effects Report #5227116-4
VELCADE problem was reported by a Physician from UNITED STATES on Jan 23, 2007. Female patient, 45 years of age, weighting 244.9 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, back pain, chest pain, dyspnoea, nausea, tachycardia, white blood cell count increased. VELCADE dosage: 1.30 MG/M2, IV BOLUS. During the same period patient was treated with DEXAMETHASONE, IBUPROFEN, ACYCLOVIR, PRILOSEC. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5228260-8
Physician from UNITED STATES reported VELCADE problem on Jan 19, 2007. Female patient, 60 years of age, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anorexia, colitis, cough, diarrhoea, diverticulum, dyspnoea exertional, fatigue, oesophagitis, pneumonia. VELCADE dosage: unknown. During the same period patient was treated with MELPHALAN, THALIDOMIDE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5228543-1
VELCADE problem was reported by a Consumer or non-health professional from CANADA on Jan 19, 2007. Male patient, 62 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, overdose. VELCADE dosage: 6.00 MG. Patient died on 03/07/2006.
Velcade Side Effects Report #5228546-7
Physician from JAPAN reported VELCADE problem on Jan 19, 2007. Female patient, 71 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: atelectasis, blood lactate dehydrogenase increased, bone marrow failure, haemorrhage, infection, interstitial lung disease, oedema peripheral, pleural effusion, pneumonia aspiration. VELCADE dosage: 1.80 MG, SEE IMAGE. During the same period patient was treated with DECADRON, SAURAMIDE, FAMOTIDINE, BAKTAR, THALIDOMIDE. Patient died on 01/07/2007.
Velcade Side Effects Report #5230502-X
VELCADE problem was reported by a Physician from GERMANY on Jan 23, 2007. Female patient, 38 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: catheter related complication, heparin-induced thrombocytopenia, hypercoagulation, peroneal nerve injury, polyneuropathy. VELCADE dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE. Patient was hospitalized and became disabled. Patient recovered.
Velcade Side Effects Report #5230504-3
Health Professional from FRANCE reported VELCADE problem on Jan 22, 2007. Male patient, 70 years of age, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: amyotrophy, diarrhoea, neuropathy peripheral. VELCADE dosage: unknown. During the same period patient was treated with THALIDOMIDE, CORTISONE ACETATE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5230506-7
VELCADE problem was reported by a Physician from NETHERLANDS on Jan 22, 2007. Female patient, 58 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: duodenal ulcer haemorrhage, multi-organ failure. VELCADE dosage: unknown. During the same period patient was treated with ONDASETRON, ESOMEPRAZOLE, FLUCONAZOLE, THIAMINE, NIFEDIPINE. Patient was hospitalized. Patient died on 09/15/2006.
Velcade Side Effects Report #5230840-0
Health Professional from UNITED STATES reported VELCADE problem on Feb 05, 2007. Male patient, 74 years of age, weighting 145.0 lb, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: inadequate analgesia, malignant neoplasm progression, pneumonia. VELCADE dosage: unknown. During the same period patient was treated with DOCETAXEL. Patient was hospitalized. Patient died on 11/03/2005.
Velcade Side Effects Report #5230843-6
VELCADE problem was reported by a Health Professional from UNITED STATES on Feb 05, 2007. Male patient, 58 years of age, weighting 172.0 lb, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cough, dyspnoea, epigastric discomfort, haematemesis, mental status changes, obstructive airways disorder, oedema, pneumonia aspiration. VELCADE dosage: unknown. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5231964-4
Physician from UNITED STATES reported VELCADE problem on Jan 26, 2007. Female patient, 59 years of age, weighting 127.0 lb, was diagnosed with mantle cell lymphoma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: colitis. VELCADE dosage: 2.1 MG, IV BOLUS. During the same period patient was treated with NORVASC, NORCO, PERCOCET, ZOFRAN, LEXAPRO. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232085-7
VELCADE problem was reported by a Physician from UNITED STATES on Jan 23, 2007. Female patient, 72 years of age, weighting 130.3 lb, was diagnosed with breast cancer and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: acute coronary syndrome, facial palsy, fall, pneumonia, transient ischaemic attack, urinary tract infection, urosepsis. VELCADE dosage: 1.30 MG/M2, UNK; INTRAVENOUS. During the same period patient was treated with TOPOTECAN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232089-4
Physician from UNITED STATES reported VELCADE problem on Jan 26, 2007. Male patient, 53 years of age, weighting 231.5 lb, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: hypoglycaemia, hypotension, syncope. VELCADE dosage: 1.30 MG/M2; UNK; INTRAVENOUS. During the same period patient was treated with BEVACIZUMAB, INSULIN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232091-2
VELCADE problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 25, 2007. Male patient, 77 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: fall, gait disturbance, weight decreased. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232312-6
Physician from FRANCE reported VELCADE problem on Jan 24, 2007. Female patient was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: confusional state, encephalopathy, somnolence, thrombocytopenia. VELCADE dosage: 1.00 MG/M2, INTRAVENOUS. During the same period patient was treated with DURAGESIC, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232385-0
VELCADE problem was reported by a Physician from AUSTRALIA on Jan 25, 2007. Female patient, 74 years of age, weighting 160.9 lb, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: balance disorder, dizziness, neurotoxicity, peripheral sensory neuropathy. VELCADE dosage: unknown. Patient recovered.
Velcade Side Effects Report #5232388-6
Physician from NETHERLANDS reported VELCADE problem on Jan 29, 2007. Female patient, 64 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. VELCADE dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS, DEXAMETHASONE, BACTRIMEL, VALACYCLOVIR, DURAGESIC. Patient died on 01/27/2007.
Velcade Side Effects Report #5232398-9
VELCADE problem was reported by a Physician from COLOMBIA on Jan 25, 2007. Female patient, 50 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: confusional state, dysarthria, eyelid ptosis. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232402-8
Physician from ITALY reported VELCADE problem on Jan 23, 2007. Male patient, 36 years of age, weighting 198.4 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: haemolytic anaemia, pyrexia, thrombocytopenia, tooth socket haemorrhage. VELCADE dosage: 2.60 MG, INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE, VALACYCLOVIR. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232403-X
VELCADE problem was reported by a Physician from NETHERLANDS on Jan 25, 2007. Male patient, 62 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, cardiac failure, cough, life support, pneumonia, respiratory failure, stem cell transplant. VELCADE dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE, MELPHALAN, ITRACONAZOLE, CEFTAZIDIME, PANTOPRAZOLE, VALACYCLOVIR, OMVIL. Patient was hospitalized. Patient died on 01/25/2007.
Velcade Side Effects Report #5232404-1
Physician from JAPAN reported VELCADE problem on Jan 26, 2007. Male patient, 78 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anaemia, anorexia, aspergillosis, blood albumin decreased, blood bilirubin increased, blood urea increased, dehydration, ecchymosis, enterococcal infection. VELCADE dosage: 1.88 MG,. During the same period patient was treated with DEXAMETHASONE, FAMOTIDINE, FLIVAS, CLINORIL, ALFAROL, METHYCOBAL, FOLIC ACID, CALCIUM LACTATE. Patient recovered.
Velcade Side Effects Report #5232405-3
VELCADE problem was reported by a Physician from GERMANY on Jan 24, 2007. Male patient, 59 years of age, weighting 209.4 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, convulsion, guillain-barre syndrome, sinoatrial block, syncope. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5232407-7
Physician from AUSTRIA reported VELCADE problem on Jan 25, 2007. Male patient, 62 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: alveolitis, blood lactate dehydrogenase increased, coagulopathy, dialysis, interstitial lung disease, leukocytosis, pneumonia, pulmonary oedema, thrombocytopenia. VELCADE dosage: 1.91 MG, INTRAVENOUS. During the same period patient was treated with DOXIL, DEXAMETHASONE, FLUCONAZOLE, HERPESIN, ISRADIPINE, HELICID, FUROSEMIDE, FRAGMIN. Patient was hospitalized. Patient died on 10/30/2006.
Velcade Side Effects Report #5232666-0
VELCADE problem was reported by a Health Professional from UNITED STATES on Feb 06, 2007. Female patient, weighting 118.2 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, cytomegalovirus oesophagitis, deep vein thrombosis, fall, febrile neutropenia, haematemesis, haemorrhage intracranial, head injury. VELCADE dosage: 1 MG/M2 IV. During the same period patient was treated with DOXORUBICIN. Patient died on 12/20/2006.
Velcade Side Effects Report #5233305-5
Physician from UNITED STATES reported VELCADE problem on Jan 31, 2007. Female patient was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: dyspnoea, pneumonia. VELCADE dosage: 1.3 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient died.
Velcade Side Effects Report #5235163-1
VELCADE problem was reported by a Physician from FRANCE on Feb 02, 2007. Male patient, 55 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: erectile dysfunction, stem cell transplant. VELCADE dosage: unknown. During the same period patient was treated with VALACYCLOVIR, DURAGESIC. Patient recovered.
Velcade Side Effects Report #5235164-3
Physician from JAPAN reported VELCADE problem on Jan 26, 2007. Male patient, 71 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase decreased, blood glucose increased, blood lactate dehydrogenase increased, blood urea decreased, blood urea increased, blood uric acid increased, c-reactive protein increased, computerised tomogram thorax abnormal, febrile neutropenia. VELCADE dosage: 1.40 MG, INTRAVENOUS. During the same period patient was treated with ZOMETA, BICARBONATE, NEUTROGIN, AMIKACIN SULPHATE, LASIX, VORICONAZOLE, RABEPRAZOLE, ENALAPRIL MALEATE. Patient recovered.
Velcade Side Effects Report #5235165-5
VELCADE problem was reported by a Physician from FRANCE on Jan 26, 2007. Female patient, 64 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anaemia, anorectal disorder, arterial thrombosis limb, back pain, cyanosis, dyspnoea, enterococcal bacteraemia, enterococcal sepsis, frequent bowel movements. VELCADE dosage: 1.80 MG, INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE, ADONA, TRANSAMIN, DOPAMINE HYDROCHLORIDE, MEROPEN, FAMOTIDINE, LASIX. Patient died on 12/25/2006.
Velcade Side Effects Report #5235166-7
Physician from JAPAN reported VELCADE problem on Jan 25, 2007. Male patient, 60 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, blood lactate dehydrogenase increased, bone formation increased, hyperkalaemia, hyperuricaemia, neuropathy peripheral, neutropenia, pyrexia, thrombocytopenia. VELCADE dosage: unknown. During the same period patient was treated with ALBUMIN, DEXAMETHASONE, MUCOSTA, ZANTAC, BAKTAR, DIFLUCAN, BIOFERMIN R, ZOVIRAX. Patient recovered.
Velcade Side Effects Report #5235167-9
VELCADE problem was reported by a Physician from IRELAND on Jan 26, 2007. Female patient, 54 years of age, weighting 145.5 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: confusional state, dyspnoea, pyrexia, supraventricular tachycardia. VELCADE dosage: 1.30 MG/M2, UNK, INTRAVENOUS. During the same period patient was treated with ADRIAMYCIN, DEXAMETHASONE, LANSOPRAZOLE, OROVITE, VALTREX, NEXIUM, SEPTRINTE, ALLOPURINOL. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5235168-0
Physician from FRANCE reported VELCADE problem on Jan 26, 2007. Male patient, 74 years of age, weighting 126.8 lb, was diagnosed with b-cell lymphoma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: confusional state, diarrhoea, lung disorder, paraesthesia, renal failure, septic shock, tachypnoea, thrombocytopenia, toxic skin eruption. VELCADE dosage: 2.40 MG, UNK, INTRAVENOUS. During the same period patient was treated with ZANIDIP, ALLOPURINOL. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236456-4
VELCADE problem was reported by a Physician from GERMANY on Jan 29, 2007. Female patient, 60 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bone pain, constipation, nausea. VELCADE dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236458-8
Consumer or non-health professional from UNITED KINGDOM reported VELCADE problem on Jan 29, 2007. Male patient, 73 years of age, weighting 194.0 lb, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, pulmonary embolism. VELCADE dosage: 1.00 MG/M2, UNK, IV BOLUS. During the same period patient was treated with ALLOPURINOL, AMITRIPTYLINE, DEXAMETHASONE, LACTULOSE, OMEPRAZOLE, OXYCONTIN, SENNA. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236460-6
VELCADE problem was reported by a Physician from CHINA on Jan 29, 2007. Male patient, 60 years of age, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: hypotension, malaise. VELCADE dosage: unknown. Patient died.
Velcade Side Effects Report #5236462-X
Physician from UNITED KINGDOM reported VELCADE problem on Jan 29, 2007. Female patient, 53 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: inappropriate antidiuretic hormone secretion. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236465-5
VELCADE problem was reported by a Physician from UNITED KINGDOM on Jan 30, 2007. Male patient, 73 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood culture positive, haemodialysis, hypotension, renal failure, renal tubular necrosis, sepsis, staphylococcal infection, tumour lysis syndrome. VELCADE dosage: 1.30 MG/M2, UNK, INTRAVENOUS. During the same period patient was treated with MELPHALAN, PAMIDRONATE DI, SULFAMETHOXAZOLE, ALLOPURINOL, PROPRANOLOL, ASPIRIN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236688-5
Health Professional from FRANCE reported VELCADE problem on Jan 30, 2007. Female patient, 51 years of age, weighting 105.8 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: jugular vein thrombosis, pyrexia. VELCADE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, CYCLOPHOSPHAMIDE, ETOPOSIDE, CISPLATIN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236690-3
VELCADE problem was reported by a Physician from JAPAN on Jan 29, 2007. Male patient, 51 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: lung disorder, malaise, po2 decreased, pyrexia. VELCADE dosage: 2.60 MG. During the same period patient was treated with ZOMETA, LANSOPRAZOLE, BAKTAK. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236691-5
Health Professional from COLOMBIA reported VELCADE problem on Jan 29, 2007. Female patient was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: multi-organ failure, sepsis, thrombocytopenia. VELCADE dosage: 1.30 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient died on 01/25/2007.
Velcade Side Effects Report #5236692-7
VELCADE problem was reported by a Physician from BRAZIL on Jan 30, 2007. Male patient, 72 years of age, weighting 154.3 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, atrioventricular block, ejection fraction decreased, lung infiltration, sepsis, urinary tract infection. VELCADE dosage: unknown. During the same period patient was treated with TYLEX, OMEPRAZOLE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236693-9
Physician from UNITED STATES reported VELCADE problem on Feb 01, 2007. Male patient, 58 years of age, weighting 162.7 lb, was diagnosed with waldenstrom's macroglobulinaemia and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cytokine release syndrome, hypersensitivity, infusion related reaction, pruritus, pyrexia, rash, vomiting. VELCADE dosage: 3.00 MG, INTRAVENOUS. During the same period patient was treated with RITUXIMAB, BECONASE, CHLORPHENAMINE, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236694-0
VELCADE problem was reported by a Physician from JAPAN on Jan 29, 2007. Male patient, 53 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anaemia, dialysis, hepatic function abnormal, platelet count decreased, renal impairment, tumour lysis syndrome. VELCADE dosage: 1.30 MG/M2. During the same period patient was treated with DEXAMETHASONE, OMEPRAL, ALLOPURINOL, MORPHNE HYDROCHLORIDE, OMEGACIN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5236938-5
Physician from UNITED STATES reported VELCADE problem on Jan 29, 2007. Male patient, 76 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: asthenia, lipase increased, pyrexia. VELCADE dosage: 1.30 MG/M2, INTRAVENOUS. During the same period patient was treated with VICODIN, FENTANYL, ARANESP, CAPECITABINE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5237063-X
VELCADE problem was reported by a Physician from RUSSIAN FEDERATION on Feb 07, 2007. Female patient, 54 years of age, weighting 145.5 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, aortic dilatation, cardiac failure chronic, cardiomyopathy, cardiovascular insufficiency, mitral valve incompetence, pneumonia, pulmonary hypertension, tricuspid valve incompetence. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5242604-2
Physician from UNITED STATES reported VELCADE problem on Feb 02, 2007. Male patient, 69 years of age, weighting 145.5 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: aphagia, colitis, renal failure, stem cell transplant. VELCADE dosage: 1.00 MG/M2, INTRAVENOUS; 1.00 MG/M2. During the same period patient was treated with MELPHALAN, DEXAMETHASONE, CISPLATIN, DOXORUBICIN, THALIDOMIDE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5242611-X
VELCADE problem was reported by a Physician from UNITED STATES on Feb 01, 2007. Male patient, 74 years of age, weighting 145.1 lb, was diagnosed with tongue cancer metastatic and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: disease progression, pain, pneumonia. VELCADE dosage: 2.90 MG, INTRAVENOUS. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient died on 11/03/2005.
Velcade Side Effects Report #5242769-2
Physician from UNITED KINGDOM reported VELCADE problem on Feb 01, 2007. Female patient, 79 years of age, weighting 130.1 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: aortic stenosis, aortic valve incompetence, bundle branch block left, cardiac failure acute, cardiomyopathy, coronary artery disease, left ventricular failure, ventricular hypokinesia. VELCADE dosage: 2.00 MG, INTRAVENOUS. During the same period patient was treated with CLODRONATE DI, ACYCLOVIR, ALLOPURINOL, DOMPERIDONE, ONDANSETRON. Patient was hospitalized and became disabled. Patient recovered.
Velcade Side Effects Report #5242770-9
VELCADE problem was reported by a Health Professional from UNITED KINGDOM on Jan 31, 2007. Male patient, 40 years of age, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: fall. VELCADE dosage: unknown. Patient was hospitalized. Patient died on 01/31/2007.
Velcade Side Effects Report #5242771-0
Physician from UNITED KINGDOM reported VELCADE problem on Jan 31, 2007. Male patient, 74 years of age, weighting 174.4 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: influenza like illness. VELCADE dosage: 2.40 MG, INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE, CLODRONATE DI. Patient recovered.
Velcade Side Effects Report #5242775-8
VELCADE problem was reported by a Pharmacist from AUSTRALIA on Feb 01, 2007. Male patient, 61 years of age, weighting 220.5 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, malignant neoplasm progression, multiple myeloma, pancytopenia. VELCADE dosage: 2.50 MG. Patient died on 01/08/2007.
Velcade Side Effects Report #5242776-X
Pharmacist from FRANCE reported VELCADE problem on Jan 31, 2007. Female patient, 79 years of age, weighting 121.3 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: plasmacytoma, pleurisy. VELCADE dosage: 1.30 MG/M2, UNK, INTRAVENOUS. During the same period patient was treated with LYTOS, DURAGESIC, ARANESP, ESOMEPRAZOLE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5242777-1
VELCADE problem was reported by a Physician from SPAIN on Feb 01, 2007. Female patient, 82 years of age, weighting 116.8 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bronchospasm, erythema, hypersensitivity, urticaria. VELCADE dosage: unknown. During the same period patient was treated with MELPHALAN, PREDNISONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5244230-8
Physician from FRANCE reported VELCADE problem on Jan 31, 2007. Male patient, 58 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: arrhythmia. VELCADE dosage: unknown. During the same period patient was treated with PERINDOPRIL ERBUMINE. Patient recovered.
Velcade Side Effects Report #5244231-X
VELCADE problem was reported by a Physician from SPAIN on Feb 01, 2007. Male patient, 64 years of age, weighting 158.7 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cytolytic hepatitis, hypotension, pleural effusion, pneumonia, renal failure, right ventricular failure, somnolence. VELCADE dosage: 2.30 MG, INTRAVENOUS. During the same period patient was treated with THALIDOMIDE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5244239-4
Physician from SWITZERLAND reported VELCADE problem on Jan 31, 2007. Male patient was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: disease progression, psychotic disorder, weight decreased. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5244276-X
VELCADE problem was reported by a Physician from FRANCE on Feb 02, 2007. Female patient, 65 years of age, weighting 119.0 lb, was diagnosed with b-cell lymphoma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: ankle fracture, complex regional pain syndrome, injury, oedema peripheral, paraesthesia, sensation of pressure. VELCADE dosage: 2.40 MG, INTRAVENOUS. Patient recovered.
Velcade Side Effects Report #5244277-1
Physician from ITALY reported VELCADE problem on Feb 02, 2007. Female patient, 67 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cytolytic hepatitis. VELCADE dosage: 2.20 MG, INTRAVENOUS. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246004-0
VELCADE problem was reported by a Physician from NETHERLANDS on Feb 07, 2007. Female patient, 53 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: hepatitis viral, herpes zoster. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246005-2
Physician from SPAIN reported VELCADE problem on Feb 09, 2007. Female patient, 77 years of age, weighting 167.6 lb, was diagnosed with multiple myeloma and was treated with VELCADE. VELCADE dosage: 1.30 MG, UNK, INTRAVENOUS. During the same period patient was treated with THALIDOMIDE, PREDNISONE. Patient died on 02/09/2007.
Velcade Side Effects Report #5246006-4
VELCADE problem was reported by a Physician from NETHERLANDS on Feb 12, 2007. Female patient, 51 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: epilepsy, escherichia bacteraemia, gastric haemorrhage, pneumococcal sepsis, pseudomonal bacteraemia, renal tubular necrosis, rhabdomyolysis. VELCADE dosage: unknown. Patient recovered.
Velcade Side Effects Report #5246007-6
Physician from SPAIN reported VELCADE problem on Feb 13, 2007. Male patient, 78 years of age, weighting 169.8 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bronchitis, febrile neutropenia, pancytopenia, performance status decreased. VELCADE dosage: 2.25 MG, UNK, INTRAVENOUS. During the same period patient was treated with THALIDOMIDE, PREDNISONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246008-8
VELCADE problem was reported by a Physician from JAPAN on Feb 05, 2007. Male patient, 51 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood lactate dehydrogenase increased, interstitial lung disease, malaise, neutropenia, pyrexia. VELCADE dosage: unknown. During the same period patient was treated with ZOMETA, LANSOPRAZOLE, BAKTAR, LOXONIN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246009-X
Physician from GERMANY reported VELCADE problem on Feb 06, 2007. Female patient, 60 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bone pain, constipation, nausea. VELCADE dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246010-6
VELCADE problem was reported by a Physician from IRELAND on Feb 06, 2007. Female patient, 54 years of age, weighting 145.5 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: confusional state, dyspnoea, pyrexia, supraventricular tachycardia. VELCADE dosage: 1.30 MG/M2, UNK, INTRAVENOUS. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE, LANSOPRAZOLE, OROVITE, VALTREX, NEXIUM, SEPTRINTE, ALLOPURINOL. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246120-3
Pharmacist from CANADA reported VELCADE problem on Feb 06, 2007. Female patient, child -1 years of age, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood creatine increased, neuropathy peripheral. VELCADE dosage: unknown. Patient recovered.
Velcade Side Effects Report #5246177-X
VELCADE problem was reported by a Physician from GERMANY on Feb 01, 2007. Male patient, 59 years of age, weighting 144.4 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: leukopenia, thrombocytopenia, urethral haemorrhage. VELCADE dosage: 2.40 MG, UNK; INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, ACETYLSALICYLIC ACID SRT, ATORVASTATIN CALCIUM, RAMIPRIL, POTASSIUM, RANITIDIN, VALERIAN ROOT, BENZBROMARONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246178-1
Health Professional from FRANCE reported VELCADE problem on Feb 09, 2007. Female patient, 51 years of age, weighting 105.8 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: jugular vein thrombosis, pyrexia. VELCADE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, CYCLOPHOSPHAMIDE, ETOPOSIDE, CISPLATIN, VALACYCLOVIR. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246179-3
VELCADE problem was reported by a Physician from FRANCE on Feb 08, 2007. Male patient, 74 years of age, weighting 126.8 lb, was diagnosed with b-cell lymphoma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: confusional state, cyanosis, diarrhoea, hypocapnia, hypotension, hypoxia, lung disorder, oedema peripheral, paraesthesia. VELCADE dosage: 2.40 MG, UNK; INTRAVENOUS. During the same period patient was treated with ZANIDIP, ALLOPURINOL. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246180-X
Physician from BRAZIL reported VELCADE problem on Feb 08, 2007. Male patient, 69 years of age, was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: amyloidosis, diarrhoea, neuropathy. VELCADE dosage: unknown. During the same period patient was treated with PREFEST. Patient recovered.
Velcade Side Effects Report #5246181-1
VELCADE problem was reported by a Physician from COLOMBIA on Feb 01, 2007. Female patient, 50 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: confusional state, dysarthria, eyelid ptosis, muscular weakness. VELCADE dosage: 1.30 MG/M2, UNK; INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246184-7
Physician from SOUTH AFRICA reported VELCADE problem on Feb 07, 2007. Female patient, 63 years of age, weighting 108.0 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bone pain, headache, hyperhidrosis, nasal congestion, pyrexia, tachycardia. VELCADE dosage: 1.50 MG, UNK; INTRAVENOUS. During the same period patient was treated with EPREX, BONDRONAT. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5246186-0
VELCADE problem was reported by a Physician from JAPAN on Feb 11, 2007. Male patient, 53 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anaemia, dialysis, gastrointestinal haemorrhage, hepatic function abnormal, platelet count decreased, pneumonia, pneumonia bacterial, renal impairment, septic shock. VELCADE dosage: 1.30 MG/M2. During the same period patient was treated with DEXAMETHASONE, OMEPRAL, ALLOPURINOL, MORPHINE, OMEGACIN. Patient was hospitalized. Patient died on 02/10/2007.
Velcade Side Effects Report #5246187-2
Physician from COLOMBIA reported VELCADE problem on Feb 08, 2007. Female patient was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, leukaemia, multi-organ failure, sepsis, thrombocytopenia. VELCADE dosage: 1.00 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient died on 01/25/2007.
Velcade Side Effects Report #5246188-4
VELCADE problem was reported by a Physician from AUSTRALIA on Feb 08, 2007. Female patient, 76 years of age, weighting 149.9 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: disease recurrence, lower respiratory tract infection, pneumonia, renal failure acute, troponin i increased. VELCADE dosage: 1.00 MG/M2, INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE, LASIX, DIGOXIN, MS CONTIN, TIMENTIN, NYSTATIN, COLOXYL WITH SENNA. Patient was hospitalized. Patient died on 02/06/2007.
Velcade Side Effects Report #5246189-6
Physician from JAPAN reported VELCADE problem on Feb 07, 2007. Male patient, 63 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood lactate dehydrogenase increased, platelet count decreased, tumour lysis syndrome, white blood cell count decreased. VELCADE dosage: 1.30 MG/M2. During the same period patient was treated with DEXAMETHASONE. Patient recovered.
Velcade Side Effects Report #5246190-2
VELCADE problem was reported by a Physician from JAPAN on Feb 09, 2007. Female patient, 71 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anaemia, blood amylase increased, coagulation time prolonged, hepatic function abnormal, nausea, neuropathy peripheral, orthostatic hypotension, platelet count decreased, urinary retention. VELCADE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, PREDNISOLONE, LANSOPRAZOLE, BAKTAR, DEPAKENE, ROHYPNOL, MARZULENE S. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5247155-7
Physician from UNITED STATES reported VELCADE problem on Nov 22, 2006. Male patient, 65 years of age, weighting 207.0 lb, was diagnosed with amyloidosis and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cellulitis, phlebitis. VELCADE dosage: 2.50 MG, IV BOLUS. Patient recovered.
Velcade Side Effects Report #5247156-9
VELCADE problem was reported by a Physician from UNITED STATES on Feb 07, 2007. Female patient, 71 years of age, weighting 205.0 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, weight decreased. VELCADE dosage: 1.30 MG/M2, INTRAVENOUS. During the same period patient was treated with AROMASIN, KYTRIL, ZOMETA. Patient recovered.
Velcade Side Effects Report #5247691-3
Physician from JAPAN reported VELCADE problem on Feb 02, 2007. Male patient, 71 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase decreased, blood glucose increased, blood lactate dehydrogenase increased, blood urea increased, blood uric acid increased, c-reactive protein increased, computerised tomogram thorax abnormal, febrile neutropenia, fungal dna test positive. VELCADE dosage: 1.40 MG, INTRAVENOUS. During the same period patient was treated with ZOMETA, BICARBONATE, NEUTROGIN, AMIKACIN SULPHATE, LASIX, VORICONAZOLE, RABEPRAZOLE, ENALAPRIL MALEATE. Patient recovered.
Velcade Side Effects Report #5247694-9
VELCADE problem was reported by a Physician from FRANCE on Feb 05, 2007. Male patient, 52 years of age, weighting 220.5 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: aggression, disinhibition, mania, persecutory delusion, tachycardia. VELCADE dosage: 1.30 MG/M2, INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5247696-2
Physician from GERMANY reported VELCADE problem on Feb 05, 2007. Male patient, 69 years of age, weighting 211.6 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, acute hepatic failure, blood glucose increased, breath sounds abnormal, cholelithiasis, cold sweat, confusional state, dyspnoea. VELCADE dosage: 2.60 MG, INTRAVENOUS. During the same period patient was treated with CIPROFLOXACIN, ACETAMINOPHEN, MORPHINE, GRANISETRON, DIPYRONE, OMEPRAZOLE, VERAPAMIL, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5247698-6
VELCADE problem was reported by a Physician from GERMANY on Feb 05, 2007. Female patient, 57 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: hyperglycaemia, polyuria. VELCADE dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE, METOPROLOL TARTRATE, OXAZEPAM, PANTOPRAZOLE. Patient recovered.
Velcade Side Effects Report #5247700-1
Physician from JAPAN reported VELCADE problem on Feb 05, 2007. Female patient, 61 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: asthenia, blood lactate dehydrogenase increased, fall, grip strength decreased, headache, loss of consciousness, pyrexia. VELCADE dosage: unknown. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5247729-3
VELCADE problem was reported by a Physician from FRANCE on Feb 05, 2007. Male patient, 58 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: agitation, back pain, cardiac failure, confusional state, mucosal inflammation, muscle rigidity, nervous system disorder, pelvic pain, purpura. VELCADE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, MELPHALAN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5247732-3
Physician from KOREA, REPUBLIC OF reported VELCADE problem on Feb 12, 2007. Female patient, 75 years of age, weighting 95.90 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, cardiac arrest, heart rate decreased, loss of proprioception, somnolence, supraventricular tachycardia. VELCADE dosage: 1.30 MG/M2, INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE. Patient died on 08/28/2006.
Velcade Side Effects Report #5247733-5
VELCADE problem was reported by a Physician from GERMANY on Feb 06, 2007. Female patient, 52 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: back pain, brain stem syndrome, cerebral infarction, coma, delirium, disturbance in attention, encephalitis viral, headache, hyperhidrosis. VELCADE dosage: unknown. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE, ACETAMINOPHEN, TILIDINE, IBUPROFEN, ALLOPURINOL, NEXIUM. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5248602-7
Physician from AUSTRALIA reported VELCADE problem on Feb 12, 2007. Male patient, 66 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: cough, dyspnoea, hypotension, hypoxia, lung injury, pyrexia, tachycardia. VELCADE dosage: 1.30 MG/M2. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE. Patient died.
Velcade Side Effects Report #5248620-9
VELCADE problem was reported by a Physician from UNITED STATES on Feb 05, 2007. Female patient, 59 years of age, weighting 127.0 lb, was diagnosed with mantle cell lymphoma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anaemia, clostridium difficile colitis, hypomagnesaemia, leukopenia, tachycardia, thrombocytopenia. VELCADE dosage: 2.1 MG, IV BOLUS. During the same period patient was treated with NORVASC, NORCO, PERCOCET, ZOFRAN, LEXAPRO, ATIVAN, VALIUM. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5248621-0
Physician from UNITED STATES reported VELCADE problem on Feb 06, 2007. Female patient, 68 years of age, was diagnosed with acute myeloid leukaemia and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: aspiration, asthma, atrial fibrillation, cardiac failure congestive, cardio-respiratory arrest, catheter site haemorrhage, diastolic dysfunction, dilatation ventricular, haematocrit decreased. VELCADE dosage: 3.30 MG, INTRAVENOUS. During the same period patient was treated with QUININE SULPHATE, BUMEX, ARIMIDEX, CELEBREX, LEVOXYL, PLAVIX, CATAPRES, PROTONIX. Patient was hospitalized. Patient died on 02/03/2007.
Velcade Side Effects Report #5248622-2
VELCADE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 12, 2007. Male patient, 63 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: blood count abnormal, viral rash. VELCADE dosage: unknown. During the same period patient was treated with THALIDOMIDE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5248722-7
Physician from UNITED STATES reported VELCADE problem on Feb 14, 2007. Female patient, 45 years of age, weighting 150.4 lb, was diagnosed with lung neoplasm malignant and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: pneumonectomy. VELCADE dosage: 0.70 MG/M2. During the same period patient was treated with CARBOPLATIN, TAXOL, WELLBUTRIN, COMPAZINE, PERCOCET. Patient was hospitalized. Patient died on 02/13/2007.
Velcade Side Effects Report #5249146-9
VELCADE problem was reported by a Physician from FRANCE on Feb 12, 2007. Female patient, 53 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bronchitis, eosinophilia, haemodialysis, rash, renal failure acute. VELCADE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, THALIDOMIDE, AUGMENTIN, CEFPODOXIME PROXETIL, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5249147-0
Physician from FRANCE reported VELCADE problem on Feb 14, 2007. Male patient, 58 years of age, weighting 114.6 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, agitation, confusional state, disorientation, dysglobulinaemia, encephalitis, extrapyramidal disorder, febrile bone marrow aplasia. VELCADE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, MELPHALAN. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5249149-4
VELCADE problem was reported by a Physician from JAPAN on Feb 16, 2007. Female patient, 58 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: anaemia, blood creatinine increased, bronchitis, carotid bruit, dehydration, diarrhoea, disease progression, increased viscosity of bronchial secretion, injury asphyxiation. VELCADE dosage: 1.30 MG/M2,. During the same period patient was treated with BAKTAR, MAGNESIUM OXIDE, FENTANYL, EBRANTIL, BESACOLIN. Patient died on 02/03/2007.
Velcade Side Effects Report #5249150-0
Physician from SWITZERLAND reported VELCADE problem on Feb 14, 2007. Male patient was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: disease progression, monoclonal immunoglobulin present, psychotic disorder, weight decreased. VELCADE dosage: unknown. Patient was hospitalized. Patient died.
Velcade Side Effects Report #5249152-4
VELCADE problem was reported by a Physician from BRAZIL on Feb 12, 2007. Male patient, 69 years of age, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: amyloidosis, neuropathy. VELCADE dosage: 1.70 MG/M2; 2.30 MG/M2. During the same period patient was treated with PREFEST. Patient recovered.
Velcade Side Effects Report #5249161-5
Physician from POLAND reported VELCADE problem on Feb 13, 2007. Male patient, 65 years of age, weighting 149.9 lb, was diagnosed with plasmacytoma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: apnoea, asthenia, chest pain, pyrexia, supraventricular tachycardia. VELCADE dosage: 2.30 MG, INTRAVENOUS. During the same period patient was treated with DOXORUBICIN, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Velcade Side Effects Report #5251952-1
VELCADE problem was reported by a Health Professional from UNITED STATES on Feb 16, 2007. Male patient, 59 years of age, weighting 149.9 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, atelectasis, dilatation atrial, dilatation ventricular, ejection fraction abnormal, mitral valve incompetence, neutropenia, septic shock, supraventricular tachycardia. VELCADE dosage: 1.20 MG/M2, UNK, INTRAVENOUS. During the same period patient was treated with ZOFRAN. Patient was hospitalized. Patient died on 02/12/2006.
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Drug Information: Bortezomib
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607007.html
bor tez' oh mibWhy is this medication prescribed?
Bortezomib is used to treat people with multiple myeloma (a type of cancer of the bone marrow) who have already been treated with at least one other medication. Bortezomib is also used to treat people with mantle cell lymphoma (a fast-growing cancer that begins in the cells of the immune system) who have already been treated with at least one other medication. Bortezomib is in a class of medications called antineoplastic agents. It works by killing cancer cells.
How should this medicine be used?
Bortezomib comes as a solution (liquid) to inject into a vein. Bortezomib is given by a doctor or nurse in a medical office or clinic. It is usually given on a rotating schedule that alternates 2 weeks when bortezomib is given twice a week with 10 days when the medication is not given. During the weeks that bortezomib is given, doses will always be at least 72 hours apart. The rotating schedule may be followed for up to eight cycles. After that, your doctor may decide to continue your treatment, but you will receive bortezomib less often.
Be sure to tell your doctor how you are feeling during your treatment. Your doctor may stop your treatment for a while or decrease your dose of bortezomib if you experience side effects of the medication.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before using bortezomib,
- tell your doctor and healthcare provider if you are allergic to bortezomib, mannitol, any other medications, or boron.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, or nutritional supplements you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone, Pacerone); cimetidine (Tagamet); clarithromycin (Biaxin, Prevpac); diltiazem (Cardizem, Dilacor, Tiazac, others); erythromycin (E.E.S., E-Mycin, Erythrocin); fluvoxamine; certain antifungals such as itraconazole (Sporanox) or ketoconazole (Nizoral); medications to treat diabetes or high blood pressure; certain medications to treat human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) such as indinavir (Crixivan), nelfinavir (Viracept), or ritonavir (Norvir); certain medications to treat seizures such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin, Phenytek); mibefradil (no longer available in the U.S.); nefazodone; rifabutin (Mycobutin); rifampin (Rifadin, Rifamate, Rimactane, others); troleandomycin (TAO) (no longer available in the U.S.); or verapamil (Calan, Covera, Isoptin, in Tarka, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you or anyone in your family has or has ever had heart disease and if you have or have ever had a herpes infection (cold sores, shingles, or genital sores); diabetes; fainting; high cholesterol (fats in the blood); low or high blood pressure; peripheral neuropathy (numbness, pain, tingling, or burning feeling in the feet or hands) or weakness or loss of feeling or reflexes in a part of your body;or kidney or liver disease. Also tell your doctor if you smoke or drink large amounts of alcohol.
- tell your doctor if you are pregnant or plan to become pregnant. Bortezomib may harm the fetus. Use birth control to prevent pregnancy during your treatment with bortezomib.Ask your doctor if you have questions about types of birth control that will work for you. If you become pregnant while using bortezomib, call your doctor immediately.
- do not breast-feed during your treatment with bortezomib. After your treatment has finished, talk to your doctor or nurse about when it is safe to restart breast-feeding.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using bortezomib.
- you should know that bortezomib may make you drowsy, dizzy, or lightheaded, or cause fainting or blurred vision. Do not drive a car or operate machinery or dangerous tools until you know how this medication affects you.
- you should know that bortezomib may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common in people who have fainted in the past, people who are dehydrated, and people who are taking medications that lower blood pressure. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
What special dietary instructions should I follow?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.
Drink plenty of fluids every day during your treatment with bortezomib, especially if you vomit or have diarrhea.
What should I do if I forget a dose?
If you miss an appointment to receive a dose of bortezomib, call your doctor right away.
What side effects can this medication cause?
Bortezomib may cause side effects. Tell your doctor if any of these symptoms, or those in the SPECIAL PRECAUTIONS section, are severe or do not go away:
- general weakness
- nausea
- vomiting
- diarrhea
- stomach pain
- anxiety
- back pain
- bone, joint, or muscle pain
- muscle cramps
- difficulty falling asleep or staying asleep
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- pain, burning, numbness, or tingling in the hands or feet
- weakness in the arms or legs
- changes in the sense of touch
- shortness of breath
- cough
- swelling of the feet, ankles, or lower legs
- hives
- rash
- itching
- difficulty breathing or swallowing
- swelling of the face, throat, tongue, lips, eyes, or hands
- hoarseness
- fever, sore throat, chills, or other signs of infection
- unusual bruising or bleeding
- black and tarry stools
- red blood in stools
- bloody vomit
- vomiting material that looks like coffee grounds
- slurred speech or inability to speak or understand speech
- loss of balance or coordination
- loss of memory
- paralysis (loss of ability to move a part of the body
- vision changes or loss of vision
- loss of consciousness
- excessive tiredness
- pale skin
- fast heartbeat
- fainting
- headache
- thoughts of harming or killing yourself
- difficulty thinking clearly, using good judgment, or understanding reality
- hallucinating (seeing things or hearing voices that do not exist)
- confusion
- restlessness
- thirst
- decreased urination
- loss of appetite
- constipation
- seizures
- skin blisters that are itchy or painful
Bortezomib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Bortezomib will be stored in the medical office or clinic.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- fainting
- dizziness
- blurred vision
- unusual bruising or bleeding
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to bortezomib.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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