Vincristine Side Effects
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Vincristine Safety Reports reported to FDA
Total Vincristine reports: 115.Vincristine FDA safety alerts: No.
Reported deaths: 32 Reported hospitalizations: 40.
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Reported Vincristine Side Effects: treatment related secondary malignancy, convulsion, pancytopenia, neuropathy peripheral, diarrhoea, dehydration, respiratory failure, colonic pseudo-obstruction, hyponatraemia, acute myeloid leukaemia, haemoglobin decreased.
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Vincristine Side Effects Report #5419342-6Pharmacist from UNITED STATES reported VINCRISTINE problem on Aug 15, 2007. Male patient, 53 years of age, was diagnosed with b-cell lymphoma and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: b-cell lymphoma, diabetic neuropathy. VINCRISTINE dosage: unknown. During the same period patient was treated with HUMALOG, WELLBUTRIN, TRAZODONE, NORVASC, LOPRESSOR, ZESTRIL, FOLIC ACID. Patient was hospitalized. Patient recovered.
Vincristine Side Effects Report #5420023-3
VINCRISTINE problem was reported by a Consumer or non-health professional from ITALY on Aug 07, 2007. Female patient, child 12 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: blood osmolarity decreased, cholelithiasis, hepatomegaly, hyponatraemia, pancreatitis acute. VINCRISTINE dosage: 2.5 MG (1 MG/ML- CYCLICAL); INTRAVENOUS (NO OTHERWISE SPECIFIED). During the same period patient was treated with ASPARAGINASE, PREDNISONE, DAUNORUBICIN, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.
Vincristine Side Effects Report #5421886-8
Physician from GERMANY reported VINCRISTINE problem on Aug 07, 2007. Male patient, child 10 years of age, was diagnosed with fibromatosis and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: coordination abnormal, fall, gait disturbance, peripheral sensorimotor neuropathy, transaminases increased. VINCRISTINE dosage: 2 MG 1 IN 1 WK INTRAVENOUS (NOT OTHERWISE SPECIFIED). Patient was hospitalized. Patient recovered.
Vincristine Side Effects Report #5422003-0
VINCRISTINE problem was reported by a Health Professional from KOREA, REPUBLIC OF on Aug 20, 2007. Male patient, child 9 years of age, was diagnosed with brain neoplasm, convulsion, caecitis and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: colonic pseudo-obstruction, pancytopenia. VINCRISTINE dosage: unknown. During the same period patient was treated with ETOPOSIDE, CISPLATIN, CARBOPLATIN, VALPROIC ACID, PHENYTOIN, TOPIRAMATE, CLONAZEPAM, ANTIBIOTICS. Patient recovered.
Vincristine Side Effects Report #5422314-9
Physician from GERMANY reported VINCRISTINE problem on Aug 07, 2007. Male patient, child 10 years of age, was diagnosed with fibromatosis and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: abasia, coordination abnormal, fall, peripheral motor neuropathy, peripheral sensory neuropathy, transaminases increased. VINCRISTINE dosage: 2 MG WEEKLY IV. Patient was hospitalized. Patient recovered.
Vincristine Side Effects Report #5423833-1
VINCRISTINE problem was reported by a Health Professional from KOREA, REPUBLIC OF on Aug 22, 2007. Male patient, child 9 years of age, was diagnosed with brain neoplasm, convulsion, caecitis and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: caecitis, colonic pseudo-obstruction, convulsion, pancytopenia, pseudomembranous colitis. VINCRISTINE dosage: unknown. During the same period patient was treated with ETOPOSIDE, CISPLATIN, CARBOPLATIN, VALPROIC ACID, PHENYTOIN, TOPIRAMATE, CLONAZEPAM, ANTIBIOTICS. Patient recovered.
Vincristine Side Effects Report #5427320-6
Consumer or non-health professional from FRANCE reported VINCRISTINE problem on Aug 13, 2007. Male patient, 61 years of age, was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: brain herniation, endocarditis staphylococcal, ischaemic stroke, lung abscess, sepsis, septic embolus. VINCRISTINE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, DOXORUBICIN. Patient died on 06/29/2007.
Vincristine Side Effects Report #5430023-5
VINCRISTINE problem was reported by a Consumer or non-health professional from KOREA, REPUBLIC OF on Aug 15, 2007. Male patient, child 9 years of age, was diagnosed with brain neoplasm and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: colonic pseudo-obstruction, ileus, pancytopenia. VINCRISTINE dosage: unknown. During the same period patient was treated with ETOPOSIDE, CISPLATIN, CARBOPLATIN, VALPROIC ACID, PHENYTOIN, TOPIRAMATE, CLONAZEPAM. Patient was hospitalized. Patient recovered.
Vincristine Side Effects Report #5441581-9
Physician from KOREA, REPUBLIC OF reported VINCRISTINE problem on Aug 13, 2007. Female patient, child 9 years of age, was diagnosed with medulloblastoma and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: caecitis, colonic pseudo-obstruction, convulsion, pancytopenia, pseudomembranous colitis. VINCRISTINE dosage: unknown. During the same period patient was treated with ETOPOSIDE, CISPLATIN, CARBOPLATIN, CLONAZEPAM. Patient was hospitalized. Patient recovered.
Vincristine Side Effects Report #5449349-4
VINCRISTINE problem was reported by a Health Professional from DENMARK on Aug 31, 2007. Female patient, child 3 years of age, was diagnosed with b precursor type acute leukaemia and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: dysphagia, mucous membrane disorder, oesophageal disorder, oesophageal stenosis. VINCRISTINE dosage: unknown. During the same period patient was treated with DOXORUBICIN, METHOTREXATE, PREDNISOLONE, MICONAZOLE, TAZOBACTAM, GENTAMICIN, FLUCONAZOLE DATES, CEFTAZIDIME. Patient recovered.
Vincristine Side Effects Report #5451829-2
Physician from ITALY reported VINCRISTINE problem on Aug 31, 2007. Male patient, 51 years of age, was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: bedridden, condition aggravated, csf protein increased, dysphagia, guillain-barre syndrome, lymphocyte count decreased, white blood cell count decreased. VINCRISTINE dosage: (1.4 MG/M2). During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, METHYLPREDNISOLONE, RITUXIMAB. Patient recovered.
Vincristine Side Effects Report #5467073-9
VINCRISTINE problem was reported by a Physician from TURKEY on Sept 10, 2007. Male patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest, cranial neuropathy, neuropathy peripheral. VINCRISTINE dosage: 1.5 MG/M2 FREQ. During the same period patient was treated with ANTRHACYCLINE. Patient recovered.
Vincristine Side Effects Report #5468557-X
Health Professional from SPAIN reported VINCRISTINE problem on Sept 25, 2007. Male patient, 19 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: lung infection pseudomonal, malignant neoplasm progression, neurotoxicity. VINCRISTINE dosage: 2 MG ON DAY 1 AND 8.. During the same period patient was treated with METHOTREXATE, HYDROCORTISONE SUCCINATE, DAUNORUBICIN, PREDNISONE, CYTARABINE, DEXAMETHASONE. Patient died.
Vincristine Side Effects Report #5472088-0
VINCRISTINE problem was reported by a Health Professional from UNITED STATES on Sept 12, 2007. Female patient, 73 years of age, was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: granulocytopenia. VINCRISTINE dosage: unknown. During the same period patient was treated with CYTOXAN, CLOZAPINE. Patient recovered.
Vincristine Side Effects Report #5474819-2
Health Professional from TURKEY reported VINCRISTINE problem on Sept 23, 2007. Male patient, 20 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: bone marrow necrosis, escherichia infection, febrile neutropenia, osteonecrosis, sepsis. VINCRISTINE dosage: 1 MG PER_CYCLE. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, DEXAMETHASONE. Patient died.
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