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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Vytorin Safety Reports submitted to FDA

Total Vytorin reports: 529.
Vytorin FDA safety alerts: 2008 .
Reported deaths: 19    Reported hospitalizations: 282.
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FDA Reported Vytorin Side Effects: rhabdomyolysis, myalgia, blood creatine phosphokinase increased, pain in extremity, asthenia, aspartate aminotransferase increased, alanine aminotransferase increased, renal failure acute, renal failure, hepatic enzyme increased, muscular weakness.
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Vytorin Side Effects Report #5279563-2
Physician from UNITED STATES reported VYTORIN problem on Mar 19, 2007. Female patient, 67 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: herpes zoster, hyperglycaemia, intestinal functional disorder, leukocytosis, muscle atrophy, polymyalgia rheumatica, rosacea, seronegative arthritis, serum sickness. VYTORIN dosage: unknown. During the same period patient was treated with ATACAND, LASIX. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5284432-8
VYTORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 30, 2007. Male patient, 72 years of age, weighting 128.0 lb, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: activities of daily living impaired, amnesia, anorexia, asthenia, asthma, back pain, balance disorder, condition aggravated, discomfort. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5283452-7
Physician from UNITED STATES reported VYTORIN problem on Mar 22, 2007. Female patient, 55 years of age, weighting 194.0 lb, was diagnosed with hyperlipidaemia, diabetes mellitus and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, cardiovascular disorder, diabetes mellitus, intervertebral disc disorder, myelopathy, weight increased. VYTORIN dosage: unknown. During the same period patient was treated with JANUVIA, NIASPAN, VICODIN, HYDROCHLOROTHIAZIDE AND LISINOPRIL, DILTIAZEM HYDROCHLORIDE, WELLBUTRIN, ACTOS. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5283453-9
VYTORIN problem was reported by a Physician from UNITED STATES on Mar 22, 2007. Male patient, 67 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: cranial nerve paralysis, lymphadenopathy, musculoskeletal stiffness, myocardial infarction, pharyngolaryngeal pain, tracheostomy infection, trismus. VYTORIN dosage: unknown. During the same period patient was treated with TETANUS TOXOID. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5283469-2
Health Professional from NETHERLANDS reported VYTORIN problem on Mar 27, 2007. Female patient, 52 years of age, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: flushing, hepatic function abnormal. VYTORIN dosage: unknown. During the same period patient was treated with ZOCOR, FUROSEMIDE, ATENOLOL, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5283893-8
VYTORIN problem was reported by a Physician from UNITED STATES on Mar 20, 2007. Male patient, 44 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: convulsion, road traffic accident. VYTORIN dosage: unknown. During the same period patient was treated with DILANTIN, LAMICTAL. Patient recovered.

Vytorin Side Effects Report #5284762-X
Physician from PORTUGAL reported VYTORIN problem on Mar 29, 2007. Female patient, 80 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, blood bilirubin increased, cholestasis, jaundice, pruritus, transaminases increased, vomiting. VYTORIN dosage: unknown. During the same period patient was treated with OXAZEPAM, INDAPAMIDE, DIOSMIN, NIMESULIDE. Patient recovered.

Vytorin Side Effects Report #5284769-2
VYTORIN problem was reported by a Health Professional from PORTUGAL on Mar 29, 2007. Female patient, weighting 176.4 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: mucosal inflammation, oral mucosal exfoliation, oral pain, paraesthesia oral. VYTORIN dosage: unknown. During the same period patient was treated with GLUCOSAMINE, FOSAMAX, CHOLECALCIFEROL, ASPIRIN. Patient recovered.

Vytorin Side Effects Report #5285415-4
Pharmacist from UNITED STATES reported VYTORIN problem on Mar 29, 2007. Female patient, 59 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, myalgia, myopathy, temporomandibular joint syndrome. VYTORIN dosage: unknown. During the same period patient was treated with DIOVAN. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5288832-1
VYTORIN problem was reported by a Physician from PORTUGAL on Mar 28, 2007. Male patient, 45 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: liver disorder. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5288849-7
Health Professional from UNITED STATES reported VYTORIN problem on Mar 29, 2007. Male patient, 57 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: gait disturbance, neuropathy peripheral. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5289249-6
VYTORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 03, 2007. Female patient, 53 years of age, weighting 136.0 lb, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: neck pain. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5289250-2
Physician from UNITED STATES reported VYTORIN problem on Apr 03, 2007. Female patient, weighting 160.0 lb, was diagnosed with blood cholesterol abnormal, c-reactive protein increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: arrhythmia, cardiac disorder, coronary artery occlusion. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5293855-2
VYTORIN problem was reported by a Physician from FRANCE on Apr 04, 2007. Male patient, 74 years of age, was diagnosed with hypercholesterolaemia, angina pectoris, prophylaxis and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: metastatic neoplasm. VYTORIN dosage: unknown. During the same period patient was treated with MOLSIDOMINE, PERINDOPRIL, DILTIAZEM HYDROCHLORIDE, CLOPIDOGREL BISULPHATE. Patient was hospitalized. Patient died on 02/04/2007.

Vytorin Side Effects Report #5294362-3
Consumer or non-health professional from UNITED STATES reported VYTORIN problem on Apr 09, 2007. Female patient, 44 years of age, weighting 183.0 lb, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, gastrointestinal disorder, headache, influenza like illness, myalgia, nausea, vomiting. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5295443-0
VYTORIN problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Female patient, 59 years of age, weighting 123.5 lb, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased, myositis. VYTORIN dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5296753-3
Physician from UNITED STATES reported VYTORIN problem on Apr 03, 2007. Male patient, 77 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: renal failure, rhabdomyolysis. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5300693-0
VYTORIN problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Male patient, 57 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, arteriosclerosis coronary artery, coronary artery thrombosis, renal failure acute, respiratory arrest, rhabdomyolysis, sepsis, septic shock. VYTORIN dosage: unknown. Patient was hospitalized and became disabled. Patient died on 03/01/2005.

Vytorin Side Effects Report #5301389-1
Consumer or non-health professional from UNITED KINGDOM reported VYTORIN problem on Apr 13, 2007. Female patient, 55 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: anorexia, arthralgia, asthenia, cholecystitis, liver function test abnormal, lower respiratory tract infection, nausea, pruritus, pyrexia. VYTORIN dosage: unknown. During the same period patient was treated with ASPIRIN, PERINDOPRIL ERBUMINE, METFORMIN, TRAMADOL HYDROCHLORIDE, BISOPROLOL, INSULIN. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5307049-5
VYTORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2007. Female patient, 37 years of age, was diagnosed with irritable bowel syndrome and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: cerebrovascular stenosis, condition aggravated, convulsion, dysarthria, facial palsy, headache, memory impairment, migraine, reading disorder. VYTORIN dosage: unknown. During the same period patient was treated with ACTOS, ZELNORM. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5310117-5
Consumer or non-health professional from GREECE reported VYTORIN problem on Apr 24, 2007. Male patient, 58 years of age, was diagnosed with hyperlipidaemia, diabetes mellitus, hypertension and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: athetosis, blood creatine phosphokinase increased, blood pressure systolic increased, restlessness. VYTORIN dosage: unknown. During the same period patient was treated with INSULIN, PERINDOPRIL, VITAMIN B. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5310542-2
VYTORIN problem was reported by a Physician from UNITED STATES on Apr 20, 2007. Male patient, 45 years of age, weighting 220.5 lb, was diagnosed with blood cholesterol increased, anxiety, hypertension, insomnia, depression and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: aspartate aminotransferase increased, blood creatine phosphokinase increased, blood creatinine increased, convulsion, syncope. VYTORIN dosage: unknown. During the same period patient was treated with ATIVAN, LOTREL, AMBIEN, PROZAC, HYTRIN. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5312427-4
Physician from PORTUGAL reported VYTORIN problem on Apr 26, 2007. Male patient, 58 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatitis toxic. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5327406-0
VYTORIN problem was reported by a Health Professional from UNITED STATES on Nov 08, 2006. Male patient, 34 years of age, weighting 224.0 lb, was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, myalgia. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5327407-2
Physician from UNITED STATES reported VYTORIN problem on Jan 03, 2007. Male patient, 47 years of age, weighting 200.0 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-20 MG/DAILY/PO. During the same period patient was treated with INDOCIN, VALTREX. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5327409-6
VYTORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 13, 2006. Male patient, 75 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: asthenia, contusion, depression, hypertension, pancreatitis, pneumonia, renal cyst, seborrhoeic keratosis, skin papilloma. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5327410-2
Physician from UNITED STATES reported VYTORIN problem on Nov 08, 2006. Male patient, 34 years of age, weighting 318.0 lb, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-20 MG/DAILY/PO. During the same period patient was treated with LOTREL, SYNTHROID. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5327411-4
VYTORIN problem was reported by a Physician from UNITED STATES on Nov 15, 2006. Female patient, 80 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: pancreatitis. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5327412-6
Physician from UNITED STATES reported VYTORIN problem on Jan 23, 2007. Male patient, 78 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: myalgia. VYTORIN dosage: unknown. During the same period patient was treated with DIOVAN, LASIX, OCUVITE, PROSCAR, INSULIN. Patient recovered.

Vytorin Side Effects Report #5327417-5
VYTORIN problem was reported by a Physician from UNITED STATES on Jan 17, 2007. Female patient was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5327779-9
Consumer or non-health professional from UNITED STATES reported VYTORIN problem on Jan 03, 2007. Female patient, 70 years of age, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: arthralgia, muscular weakness, myalgia. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5327781-7
VYTORIN problem was reported by a Physician from UNITED STATES on Dec 26, 2006. Female patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5327782-9
Physician from UNITED STATES reported VYTORIN problem on Dec 15, 2006. Male patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme abnormal. VYTORIN dosage: 10-20 MG/DAILY/PO. During the same period patient was treated with TRICOR. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5327786-6
VYTORIN problem was reported by a Physician from UNITED STATES on Dec 07, 2006. Male patient, 67 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased. VYTORIN dosage: 10-10 MG/PO. During the same period patient was treated with ZOCOR. Patient recovered.

Vytorin Side Effects Report #5327787-8
Consumer or non-health professional from UNITED STATES reported VYTORIN problem on Dec 07, 2006. Male patient, 68 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, muscular weakness. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5327790-8
VYTORIN problem was reported by a Physician from UNITED STATES on Nov 22, 2006. Female patient, 79 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: polymyalgia rheumatica. VYTORIN dosage: 10-20 MG/DAILY/PO. During the same period patient was treated with FOSAMAX, SYNTHROID, CALCIUM CHLORIDE, ENALAPRIL MALEATE, PROPRANOLOL HYDROCHLORIDE, VITAMIN. Patient recovered.

Vytorin Side Effects Report #5327791-X
Physician from UNITED STATES reported VYTORIN problem on Nov 17, 2006. Female patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: ejection fraction decreased, hepatic enzyme increased. VYTORIN dosage: unknown. During the same period patient was treated with ALCOHOL, DIURETIC, VERAPAMIL. Patient was hospitalized. Patient died.

Vytorin Side Effects Report #5327799-4
VYTORIN problem was reported by a Physician from UNITED STATES on Oct 25, 2006. Female patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased. VYTORIN dosage: 10-40 MG/DAILY/PO. Patient recovered.

Vytorin Side Effects Report #5315213-4
Health Professional from UNITED STATES reported VYTORIN problem on Apr 23, 2007. Female patient, 84 years of age, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: asthenia, blood creatine phosphokinase increased, blood creatinine increased, myalgia. VYTORIN dosage: unknown. During the same period patient was treated with COREG, PLAVIX, IMURAN, RENAGEL, CYCLOSPORINE. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5315224-9
VYTORIN problem was reported by a Physician from PORTUGAL on Apr 26, 2007. Male patient, 46 years of age, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: aphasia, laryngeal oedema. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5316780-7
Pharmacist from UNITED STATES reported VYTORIN problem on Apr 24, 2007. Male patient, 73 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: dementia. VYTORIN dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5317603-2
VYTORIN problem was reported by a Physician from UNITED STATES on Apr 27, 2007. Female patient, 37 years of age, was diagnosed with irritable bowel syndrome and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: cerebrovascular stenosis, condition aggravated, convulsion, dysarthria, facial palsy, headache, memory impairment, migraine, reading disorder. VYTORIN dosage: unknown. During the same period patient was treated with ACTOS, ZELNORM. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5317754-2
Physician from UNITED STATES reported VYTORIN problem on May 02, 2007. Male patient, 41 years of age, weighting 170.0 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: convulsion, road traffic accident. VYTORIN dosage: unknown. During the same period patient was treated with PHENYTOIN. Patient recovered.

Vytorin Side Effects Report #5317977-2
VYTORIN problem was reported by a Physician from FRANCE on Nov 24, 2006. Female patient, 61 years of age, was diagnosed with hypercholesterolaemia, ankylosing spondylitis, hypothyroidism, gastritis and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: renal failure. VYTORIN dosage: unknown. During the same period patient was treated with TRAMADOL HYDROCHLORIDE, LEVOTHYROXINE, LANSOPRAZOLE. Patient recovered.

Vytorin Side Effects Report #5319660-6
Health Professional from SWITZERLAND reported VYTORIN problem on Apr 27, 2007. Male patient, 48 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: myositis. VYTORIN dosage: unknown. During the same period patient was treated with ATORVASTATIN CALCIUM, EZETIMIBE. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5321899-0
VYTORIN problem was reported by a Physician from UNITED STATES on Apr 03, 2007. Male patient, 77 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: renal failure, rhabdomyolysis. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5322496-3
Health Professional from UNITED STATES reported VYTORIN problem on May 01, 2007. Female patient, 86 years of age, weighting 165.3 lb, was diagnosed with lipids increased, arthralgia, depression, gastrooesophageal reflux disease and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: myalgia. VYTORIN dosage: unknown. During the same period patient was treated with OMEGA, GLUCOSAMINE, UBIDECARENONE, ZOLOFT, ACIPHEX. Patient recovered.

Vytorin Side Effects Report #5322497-5
VYTORIN problem was reported by a Pharmacist from UNITED STATES on May 01, 2007. Female patient, 59 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: gait disturbance, rhabdomyolysis, temporomandibular joint syndrome. VYTORIN dosage: unknown. During the same period patient was treated with DIOVAN. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5323661-1
Consumer or non-health professional from UNITED STATES reported VYTORIN problem on May 11, 2007. Male patient, 60 years of age, weighting 240.0 lb, was diagnosed with dyslipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: nausea, vomiting. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5327690-3
VYTORIN problem was reported by a Physician from UNITED STATES on May 08, 2007. Male patient, 44 years of age, weighting 169.8 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: convulsion, road traffic accident. VYTORIN dosage: unknown. During the same period patient was treated with DILANTIN, LAMICTAL. Patient recovered.

Vytorin Side Effects Report #5327696-4
Physician from UNITED STATES reported VYTORIN problem on May 07, 2007. Male patient, 80 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: renal failure, rhabdomyolysis. VYTORIN dosage: unknown. Patient was hospitalized and became disabled. Patient died on 05/04/2007.

Vytorin Side Effects Report #5328076-8
VYTORIN problem was reported by a Physician from VENEZUELA on May 14, 2007. Female patient, 63 years of age, weighting 110.2 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: asthenia, back pain, hypotension, jaundice, myocardial infarction, shock, vertigo. VYTORIN dosage: unknown. During the same period patient was treated with METFORMIN HYDROCHLORIDE, PENTOXIFYLLINE, GLYBURIDE. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5328299-8
Pharmacist from UNITED STATES reported VYTORIN problem on May 15, 2007. Male patient was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: pain in extremity. VYTORIN dosage: unknown. During the same period patient was treated with CYMBALTA, MORPHINE, TEMAZEPAM, OMEPRAZOLE, DOVONEX, LIDODERM, ASPIRIN. Patient recovered.

Vytorin Side Effects Report #5328818-1
VYTORIN problem was reported by a Consumer or non-health professional from UNITED STATES on May 11, 2007. Female patient, 54 years of age, was diagnosed with dyslipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: bone disorder, myalgia. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5331226-0
Physician from UNITED STATES reported VYTORIN problem on May 11, 2007. Male patient, 67 years of age, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, renal failure, rhabdomyolysis. VYTORIN dosage: unknown. During the same period patient was treated with DILTIAZEM CD, AMIODARONA, METOPROLOL, LASIX, AMITRIPTYLINE HYDROCHLORIDE, LORAZEPAM, LEVOTHYROXINE, ISOSORBIDE DINITRATE. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5331236-3
VYTORIN problem was reported by a Pharmacist from UNITED STATES on May 18, 2007. Male patient, 73 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: dementia, encephalopathy. VYTORIN dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5332739-8
Physician from UNITED STATES reported VYTORIN problem on May 17, 2007. Male patient, 25 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: complex partial seizures. VYTORIN dosage: unknown. During the same period patient was treated with LAMICTAL, PHENYTOIN. Patient recovered.

Vytorin Side Effects Report #5337581-X
VYTORIN problem was reported by a Physician from UNITED STATES on May 23, 2007. Female patient, 56 years of age, was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, hepatic failure. VYTORIN dosage: unknown. During the same period patient was treated with PLAVIX, ZOCOR, ZETIA. Patient was hospitalized. Patient died on 02/08/2007.

Vytorin Side Effects Report #5339291-1
Physician from UNITED STATES reported VYTORIN problem on May 29, 2007. Female patient, 59 years of age, weighting 207.2 lb, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: dermatomyositis, gait disturbance, rhabdomyolysis, temporomandibular joint syndrome. VYTORIN dosage: unknown. During the same period patient was treated with DIOVAN. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5341573-4
VYTORIN problem was reported by a Physician from UNITED STATES on May 29, 2007. Male patient, weighting 218.0 lb, was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: unknown. During the same period patient was treated with DOXAZOSIN MESYLATE, NORVASC, ASPIRIN, LUVOX, ATENOLOL, COUMADIN, ALLOPURINOL, ACTOS. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5341596-5
Physician from UNITED STATES reported VYTORIN problem on May 29, 2007. Female patient, weighting 185.0 lb, was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: asthenia, myalgia. VYTORIN dosage: unknown. During the same period patient was treated with FLONASE, DOXAZOSIN MESYLATE, TRAZODONE, DIOVAN HCT, ASPIRIN, PRILOSEC. Patient recovered.

Vytorin Side Effects Report #5341765-4
VYTORIN problem was reported by a Health Professional from UNITED STATES on May 29, 2007. Male patient, weighting 195.0 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: cholecystitis, influenza like illness. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355167-8
Physician from UNITED STATES reported VYTORIN problem on Jan 30, 2007. Female patient was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased. VYTORIN dosage: 10-80 MG/DAILY/PO. During the same period patient was treated with CHANTIX. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355169-1
VYTORIN problem was reported by a Physician from UNITED STATES on Jan 30, 2007. Female patient, 73 years of age, weighting 157.0 lb, was diagnosed with hypercholesterolaemia, routine health maintenance and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: iron deficiency anaemia, occult blood positive, pancreatitis acute, pancreatitis relapsing. VYTORIN dosage: 10-10 MG/DAILY/PO. During the same period patient was treated with BENICAR, LEVOXYL, ASPIRIN, HYDROCHLOROTHIAZIDE, LABETALOL HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355171-X
Physician from UNITED STATES reported VYTORIN problem on Jan 29, 2007. Female patient was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: unknown. During the same period patient was treated with BIAXIN. Patient recovered.

Vytorin Side Effects Report #5355174-5
VYTORIN problem was reported by a Health Professional from UNITED STATES on Jan 25, 2007. Female patient, 61 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: blood cholesterol decreased, muscular weakness, myalgia. VYTORIN dosage: 10-40 MG/DAILY/PO. During the same period patient was treated with LANTUS, INSULIN. Patient recovered.

Vytorin Side Effects Report #5355175-7
Physician from UNITED STATES reported VYTORIN problem on Jan 24, 2007. Male patient, 64 years of age, weighting 215.0 lb, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: angioedema, urticaria. VYTORIN dosage: 10-40 MG/PO. During the same period patient was treated with ESTER, TOPROL, ASPIRIN, HYDROCHLOROTHIAZIDE, LISINOPRIL. Patient recovered.

Vytorin Side Effects Report #5355386-0
VYTORIN problem was reported by a Physician from UNITED STATES on Mar 29, 2007. Female patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-80 MG/PO. During the same period patient was treated with VERAPAMIL EXTENDED. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5355394-X
Physician from UNITED STATES reported VYTORIN problem on Mar 20, 2007. Male patient, 72 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-80 MG/DAILY/PO. During the same period patient was treated with LOPID. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355398-7
VYTORIN problem was reported by a Health Professional from UNITED STATES on Mar 15, 2007. Female patient was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased, lung neoplasm malignant. VYTORIN dosage: unknown. During the same period patient was treated with FOSAMAX. Patient recovered.

Vytorin Side Effects Report #5355401-4
Physician from UNITED STATES reported VYTORIN problem on Mar 15, 2007. Female patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-10 MG/DAILY/PO. During the same period patient was treated with OMEGA. Patient recovered.

Vytorin Side Effects Report #5355406-3
VYTORIN problem was reported by a Physician from UNITED STATES on Mar 14, 2007. Male patient, 38 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. VYTORIN dosage: 10-20 MG/DAILY/PO. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355410-5
Physician from UNITED STATES reported VYTORIN problem on Mar 14, 2007. Female patient, 65 years of age, weighting 152.0 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: fatigue, myalgia, nausea. VYTORIN dosage: 10-10 MG/DAILY/PO. During the same period patient was treated with COLACE, NEURONTIN, WELLBUTRIN, ALBUTEROL. Patient recovered.

Vytorin Side Effects Report #5355417-8
VYTORIN problem was reported by a Physician from UNITED STATES on Mar 13, 2007. Female patient was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, rhabdomyolysis. VYTORIN dosage: 10-80 MG/DAILY/PO. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355424-5
Consumer or non-health professional from UNITED STATES reported VYTORIN problem on Mar 12, 2007. Female patient was diagnosed with low density lipoprotein increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: adverse event, blood creatine phosphokinase increased, myalgia. VYTORIN dosage: 10-80 MG/DAILY/PO. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355541-X
VYTORIN problem was reported by a Physician from UNITED STATES on Mar 08, 2007. Female patient was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5355545-7
Health Professional from UNITED STATES reported VYTORIN problem on Mar 09, 2007. Male patient, 68 years of age, weighting 202.0 lb, was diagnosed with blood cholesterol increased, dyslipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: renal failure acute, rhabdomyolysis. VYTORIN dosage: 10-80 MG/DAILY/PO. During the same period patient was treated with COREG, LIPITOR, ZOCOR, DIGOXIN, SPIRONOLACTONE. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5355549-4
VYTORIN problem was reported by a Physician from UNITED STATES on Mar 06, 2007. Female patient was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355554-8
Physician from UNITED STATES reported VYTORIN problem on Mar 02, 2007. Female patient was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5355557-3
VYTORIN problem was reported by a Physician from UNITED STATES on Feb 26, 2007. Female patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-20 MG/DAILY/PO. Patient recovered.

Vytorin Side Effects Report #5355561-5
Physician from UNITED STATES reported VYTORIN problem on Feb 19, 2007. Female patient, 81 years of age, weighting 149.0 lb, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-40 MG/HS/PO. During the same period patient was treated with ALLEGRA, CALTRATE, FORTEO, HUMALOG, LANTUS, MOBIC, NEURONTIN, PROTONIX. Patient recovered.

Vytorin Side Effects Report #5355562-7
VYTORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 14, 2007. Male patient, 53 years of age, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: muscular weakness, nausea. VYTORIN dosage: 10-40 MG/DAILY/PO. During the same period patient was treated with METFORMIN. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355564-0
Health Professional from UNITED STATES reported VYTORIN problem on Feb 07, 2007. Female patient, 79 years of age, weighting 170.0 lb, was diagnosed with dyslipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, muscular weakness, musculoskeletal discomfort, myalgia. VYTORIN dosage: 10-80 MG/DAILY/PO. During the same period patient was treated with TOPROL. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355567-6
VYTORIN problem was reported by a Physician from UNITED STATES on Feb 06, 2007. Male patient was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: myalgia. VYTORIN dosage: 10-20 MG/PO. Patient recovered.

Vytorin Side Effects Report #5355569-X
Consumer or non-health professional from UNITED STATES reported VYTORIN problem on Feb 05, 2007. Female patient, 51 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-80 MG/DAILY/PO. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355984-4
VYTORIN problem was reported by a Health Professional from UNITED STATES on Apr 02, 2007. Male patient, 56 years of age, weighting 218.0 lb, was diagnosed with hypercholesterolaemia, hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, blood amylase increased, lipase increased, myalgia. VYTORIN dosage: unknown. During the same period patient was treated with ZETIA, NORVASC, PREVACID, ASPIRIN, GLUCOSAMINE. Patient recovered.

Vytorin Side Effects Report #5355988-1
Health Professional from UNITED STATES reported VYTORIN problem on Apr 03, 2007. Female patient, 54 years of age, was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: pancreatitis acute. VYTORIN dosage: 10-20 MG/DAILY/PO. During the same period patient was treated with LOTREL, ATENOLOL. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355989-3
VYTORIN problem was reported by a Health Professional from UNITED STATES on Feb 07, 2007. Male patient was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme abnormal. VYTORIN dosage: 10-20 MG/DAILY/PO. During the same period patient was treated with TRICOR. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5355990-X
Health Professional from UNITED STATES reported VYTORIN problem on Jan 31, 2007. Female patient was diagnosed with blood cholesterol increased, hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: acarodermatitis, pruritus. VYTORIN dosage: 10-20 MG/DAILY/PO. During the same period patient was treated with COUMADIN, MAXZIDE, REMERON, ATENOLOL. Patient recovered.

Vytorin Side Effects Report #5355991-1
VYTORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 23, 2007. Female patient was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: unknown. Patient recovered.

Vytorin Side Effects Report #5355992-3
Physician from UNITED STATES reported VYTORIN problem on Apr 20, 2007. Male patient was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: adverse event, rhabdomyolysis. VYTORIN dosage: unknown. During the same period patient was treated with AMIODARONA, DILTIAZEM MSD. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355994-7
VYTORIN problem was reported by a Physician from UNITED STATES on Apr 17, 2007. Female patient was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, myalgia. VYTORIN dosage: 10-40 MG/DAILY/PO. Patient recovered.

Vytorin Side Effects Report #5355995-9
Physician from UNITED STATES reported VYTORIN problem on Apr 16, 2007. Female patient, 65 years of age, was diagnosed with hypercholesterolaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: pancreatitis. VYTORIN dosage: unknown. During the same period patient was treated with ACTONEL, GLUCOVANCE, PRINIVIL, SYNTHROID, ASPIRIN. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5355999-6
VYTORIN problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Female patient, 64 years of age, weighting 136.0 lb, was diagnosed with blood cholesterol increased and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5384988-0
Physician from UNITED STATES reported VYTORIN problem on Apr 09, 2007. Male patient, 65 years of age, was diagnosed with blood cholesterol and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. VYTORIN dosage: 10-40 MG/DAILY/PO. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5342809-6
VYTORIN problem was reported by a Physician from GERMANY on May 31, 2007. Male patient, 73 years of age, weighting 172.0 lb, was diagnosed with myocardial infarction, urinary tract infection and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: renal failure acute, urinary tract infection. VYTORIN dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, OMEPRAZOLE, BISOPROLOL. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5342816-3
Physician from UNITED STATES reported VYTORIN problem on May 24, 2007. Female patient, 56 years of age, was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, diverticulum intestinal haemorrhagic, hepatic failure. VYTORIN dosage: unknown. During the same period patient was treated with PLAVIX, ZOCOR, ZETIA, ASPIRIN, PRINIVIL. Patient was hospitalized. Patient died on 02/08/2007.

Vytorin Side Effects Report #5349546-2
VYTORIN problem was reported by a Physician from UNITED KINGDOM on May 31, 2007. Male patient, 43 years of age, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. VYTORIN dosage: unknown. Patient was hospitalized. Patient recovered.

Vytorin Side Effects Report #5352577-X
Physician from UNITED STATES reported VYTORIN problem on June 05, 2007. Female patient, 59 years of age, weighting 123.5 lb, was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased, rhabdomyolysis. VYTORIN dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Vytorin Side Effects Report #5355458-0
VYTORIN problem was reported by a Physician from UNITED STATES on June 11, 2007. Female patient, weighting 158.0 lb, was diagnosed with hyperlipidaemia and was treated with VYTORIN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, rash erythematous, rhabdomyolysis. VYTORIN dosage: unknown. During the same period patient was treated with UROSODIOL, GEMFIBROZIL, CENTRUM, FOLIC ACID, VITAMIN B. Patient recovered.

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Drug Information: Simvastatin

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a692030.html

(sim' va stat in)

Why is this medication prescribed?

Simvastatin is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and certain other fatty substances in your blood. Simvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body.

Buildup of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to decrease your chances of getting heart disease, angina (chest pain), strokes, and heart attacks. In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your cholesterol blood levels. You should eat a diet that is low in saturated fat and cholesterol (see SPECIAL DIETARY), exercise 30 minutes on most, if not all days, and lose weight if you are overweight.

How should this medicine be used?

Simvastatin comes as a tablet to take by mouth. It usually is taken one to three times a day . Take simvastatin at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take simvastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of simvastatin and gradually increase your dose, not more than once every 4 weeks.

Continue to take simvastatin even if you feel well. Do not stop taking simvastatin without talking to your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking simvastatin,

  • tell your doctor and pharmacist if you are allergic to simvastatin or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone, Pacerone); antifungal medications such as itraconazole (Sporanox) and ketoconazole (Nizoral); anticoagulants ('blood thinners') such as warfarin (Coumadin); cholestyramine (Questran), clarithromycin (Biaxin), clofibrate (Atromid-S), cyclosporine (Sandimmune, Neoral), danazol; digoxin (Lanoxin), erythromycin (E.E.S., E-Mycin, Erythrocin); HIV protease inhibitors such as indinavir (Crixivan), ritonavir (Norvir) and saquinavir (Invirase, Fortovase); nefazodone (Serzone); other cholesterol-lowering medications such as fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (nicotinic acid, Niacor, Niaspan); nefazodone (Serzone), and telithromycin (Ketek); and verapamil (Calan, Covera, Isoptin, Verelan). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have liver disease. Your doctor will probably tell you not to take simvastatin.
  • tell your doctor if you drink large amounts of alcohol, if you have ever had liver disease or if you have or have ever had kidney disease.
  • tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking simvastatin, stop taking simvastatin and call your doctor immediately. Simvastatin can harm the fetus.
  • Do not breast-feed while you are taking this medication.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking simvastatin.
  • ask your doctor about the safe use of alcoholic beverages while you are taking simvastatin. Alcohol can increase the risk of serious side effects.

What special dietary instructions should I follow?

Avoid drinking large quantities (more than 1 quart a day) of grapefruit juice while taking simvastatin.

Eat a low-cholesterol, low-fat diet. This kind of diet includes cottage cheese, fat-free milk, fish (not canned in oil), vegetables, poultry, egg whites, and polyunsaturated oils and margarines (corn, safflower, canola, and soybean oils). Avoid foods with excess fat in them such as meat (especially liver and fatty meat), egg yolks, whole milk, cream, butter, shortening, lard, pastries, cakes, cookies, gravy, peanut butter, chocolate, olives, potato chips, coconut, cheese (other than cottage cheese), coconut oil, palm oil, and fried foods.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Simvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • constipation

If you experience the following symptoms, call your doctor immediately:

  • muscle pain, tenderness, or weakness
  • lack of energy
  • fever
  • yellowing of the skin or eyes
  • pain in the upper right part of the stomach
  • nausea
  • extreme tiredness
  • unusual bleeding or bruising
  • loss of appetite
  • flu-like symptoms
  • rash
  • hives
  • itching
  • difficulty breathing or swallowing
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before and during treatment to check your response to simvastatin.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking simvastatin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

  • Vytorin®
  • Zocor®

Ask Our Patient Community about Vytorin

PatientsVille.com does not provide medical advice, diagnosis or treatment. The information contained on PatientsVille.com site has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of adverse drug reactions or for establishing or changing of patient treatments.


Thank you for visiting Patientsville.com. We hope you found our information about prescription drug side effects helpful. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Thank you for visiting Patientsville.net. Hope you enjoyed finding Vytorin safety information and found answers to Your Questions about Vytorin side effects

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