Xeloda Safety Reports submitted to FDA

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Total Xeloda reports: 523.
Xeloda FDA safety alerts: 2001 .
Reported deaths: 156 Reported hospitalizations: 225.
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FDA Reported Xeloda Side Effects: palmar-plantar erythrodysaesthesia syndrome, diarrhoea haemorrhagic, diarrhoea, death, vomiting, dehydration, asthenia, nausea, mucosal inflammation, stomatitis, renal failure acute.
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Xeloda Side Effects Report #5373945-6
Physician from UNITED STATES reported XELODA problem on Feb 19, 2007. Male patient, 54 years of age, was diagnosed with neoplasm malignant and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: dysphagia, malignant neoplasm progression, neoplasm malignant. XELODA dosage: unknown. Patient died on 12/04/2006.

Xeloda Side Effects Report #5374140-7
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 21, 2006. Female patient, 78 years of age, weighting 210.1 lb, was diagnosed with gastrointestinal carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1500 MG 2 PER 1 DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374141-9
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 21, 2006. Female patient, 67 years of age, weighting 131.0 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1500 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374142-0
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 27, 2006. Female patient, 66 years of age, weighting 110.0 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: nausea. XELODA dosage: 800 MG DAILY ORAL. Patient recovered.

Xeloda Side Effects Report #5374143-2
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 30, 2006. Female patient, 51 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died on 11/29/2006.

Xeloda Side Effects Report #5374144-4
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 29, 2006. Female patient, 41 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died on 11/18/2006.

Xeloda Side Effects Report #5374146-8
Physician from UNITED STATES reported XELODA problem on Nov 29, 2006. Female patient, 48 years of age, was diagnosed with metastatic neoplasm and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: metastatic neoplasm. XELODA dosage: unknown. Patient died on 09/01/2006.

Xeloda Side Effects Report #5374149-3
XELODA problem was reported by a Physician from UNITED STATES on Dec 04, 2006. Female patient, 68 years of age, weighting 112.0 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: brain neoplasm malignant, breast cancer metastatic. XELODA dosage: 2000 MG 2 PER DAY ORAL. Patient died on 11/15/2006.

Xeloda Side Effects Report #5374150-X
Consumer or non-health professional from UNITED STATES reported XELODA problem on Dec 02, 2006. Female patient, weighting 154.1 lb, was diagnosed with colon cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: abdominal pain, dehydration, diarrhoea haemorrhagic, vomiting. XELODA dosage: 1500 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374152-3
XELODA problem was reported by a Physician from UNITED STATES on Dec 01, 2006. Female patient, 58 years of age, was diagnosed with colorectal cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: colorectal cancer metastatic. XELODA dosage: 2500 MG DAILY ORAL. During the same period patient was treated with ALPRAZOLAM, PAU D, VITAMIN NOS. Patient died.

Xeloda Side Effects Report #5374154-7
Consumer or non-health professional from UNITED STATES reported XELODA problem on Dec 01, 2006. Female patient, 70 years of age, was diagnosed with colorectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: vomiting. XELODA dosage: 1500 MG DAILY ORAL. Patient recovered.

Xeloda Side Effects Report #5374156-0
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 04, 2006. Female patient, 62 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. XELODA dosage: unknown. Patient died on 08/19/2006.

Xeloda Side Effects Report #5374157-2
Consumer or non-health professional from UNITED STATES reported XELODA problem on Dec 05, 2006. Female patient, 58 years of age, was diagnosed with colorectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea. XELODA dosage: 1000 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374159-6
XELODA problem was reported by a Physician from UNITED STATES on Dec 05, 2006. Female patient, 70 years of age, weighting 147.0 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: breast cancer metastatic. XELODA dosage: unknown. Patient died on 09/09/2006.

Xeloda Side Effects Report #5374161-4
Health Professional from UNITED STATES reported XELODA problem on Dec 06, 2006. Female patient was diagnosed with breast cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: dehydration, stomatitis. XELODA dosage: unknown. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374164-X
XELODA problem was reported by a Health Professional from UNITED STATES on Dec 07, 2006. Male patient, 71 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: neoplasm malignant. XELODA dosage: unknown. Patient died on 12/05/2006.

Xeloda Side Effects Report #5374167-5
Physician from UNITED STATES reported XELODA problem on Dec 05, 2006. Female patient, 58 years of age, was diagnosed with rectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea. XELODA dosage: 3000 MG ORAL. Patient recovered.

Xeloda Side Effects Report #5374168-7
XELODA problem was reported by a Physician from UNITED STATES on Dec 21, 2006. Female patient, 58 years of age, was diagnosed with breast cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: breast cancer, malignant neoplasm progression, metastases to bone. XELODA dosage: unknown. Patient died on 11/29/2006.

Xeloda Side Effects Report #5374169-9
Physician from UNITED STATES reported XELODA problem on Nov 01, 2006. Female patient, 62 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374170-5
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 02, 2006. Male patient, 73 years of age, weighting 200.0 lb, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1500 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374171-7
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 03, 2006. Male patient, 83 years of age, weighting 361.6 lb, was diagnosed with pharyngeal cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: dehydration. XELODA dosage: 1500 MG 2 PER DAY ORAL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374172-9
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 03, 2006. Female patient, 82 years of age, was diagnosed with brain neoplasm and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: brain neoplasm, cerebrovascular accident, diarrhoea. XELODA dosage: unknown. Patient died on 10/01/2006.

Xeloda Side Effects Report #5374173-0
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 06, 2006. Female patient, 70 years of age, weighting 104.9 lb, was diagnosed with colorectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: vomiting. XELODA dosage: 2000 MG 2 PER DAY. Patient recovered.

Xeloda Side Effects Report #5374174-2
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 06, 2006. Female patient, 55 years of age, weighting 140.0 lb, was diagnosed with breast cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea, palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 2000 MG 2 PER DAY ORAL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374176-6
Pharmacist from UNITED STATES reported XELODA problem on Apr 07, 2004. Male patient, 60 years of age, was diagnosed with rectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: cardiotoxicity, chest pain. XELODA dosage: 1250 MG/M2 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374177-8
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 08, 2006. Female patient, 86 years of age, weighting 144.0 lb, was diagnosed with neoplasm malignant and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: unknown. Patient recovered.

Xeloda Side Effects Report #5374178-X
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 08, 2006. Female patient, 76 years of age, weighting 121.0 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1500 MG 2 PER DAY ORAL. During the same period patient was treated with VITAMIN B6. Patient recovered.

Xeloda Side Effects Report #5374179-1
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 09, 2006. Male patient, 73 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374180-8
Physician from UNITED STATES reported XELODA problem on Nov 10, 2006. Male patient, 74 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374181-X
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 13, 2006. Male patient, 71 years of age, weighting 194.0 lb, was diagnosed with colorectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 3000 MG DAILY ORAL. Patient recovered.

Xeloda Side Effects Report #5374182-1
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 14, 2006. Male patient, 82 years of age, weighting 330.7 lb, was diagnosed with colorectal cancer metastatic and was treated with XELODA. XELODA dosage: 1000 MG 2 PER DAY ORAL. Patient died on 11/08/2006.

Xeloda Side Effects Report #5374183-3
XELODA problem was reported by a Physician from UNITED STATES on Nov 15, 2006. Female patient, 67 years of age, weighting 163.1 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea, palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1250 MG/M2 2 PER DAY ORAL. During the same period patient was treated with LISINOPRIL. Patient recovered.

Xeloda Side Effects Report #5374184-5
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 15, 2006. Female patient, 54 years of age, weighting 151.9 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: neutropenia, pyrexia. XELODA dosage: 1500 MG 2 PER DAY ORAL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374185-7
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 17, 2006. Female patient, 65 years of age, was diagnosed with breast cancer metastatic, metastases to bone and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: neoplasm malignant. XELODA dosage: unknown. Patient died on 11/02/2006.

Xeloda Side Effects Report #5374186-9
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 20, 2006. Female patient, 57 years of age, weighting 136.9 lb, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea. XELODA dosage: 1000 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374187-0
XELODA problem was reported by a Pharmacist from UNITED STATES on Nov 20, 2006. Male patient, 56 years of age, weighting 160.1 lb, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: pancreatic carcinoma. XELODA dosage: 2500 MG DAILY ORAL. During the same period patient was treated with GEMZAR. Patient died on 11/13/2006.

Xeloda Side Effects Report #5374188-2
Consumer or non-health professional from UNITED STATES reported XELODA problem on Nov 20, 2006. Female patient, 43 years of age, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1500 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374189-4
XELODA problem was reported by a Physician from UNITED STATES on Sept 28, 2006. Male patient, 45 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: oesophageal carcinoma. XELODA dosage: unknown. Patient died on 09/26/2006.

Xeloda Side Effects Report #5374190-0
Physician from UNITED STATES reported XELODA problem on Sept 29, 2006. Female patient, 59 years of age, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: pancreatic carcinoma. XELODA dosage: unknown. Patient died on 08/16/2006.

Xeloda Side Effects Report #5374191-2
XELODA problem was reported by a Physician from UNITED STATES on Sept 29, 2006. Female patient, 56 years of age, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: breast cancer metastatic. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374192-4
Physician from UNITED STATES reported XELODA problem on Oct 05, 2006. Female patient, 54 years of age, was diagnosed with metastatic neoplasm and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: metastatic neoplasm. XELODA dosage: unknown. Patient died on 09/23/2006.

Xeloda Side Effects Report #5374194-8
XELODA problem was reported by a Physician from UNITED STATES on Oct 09, 2006. Female patient was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: renal failure. XELODA dosage: unknown. During the same period patient was treated with ELOXATIN. Patient recovered.

Xeloda Side Effects Report #5374195-X
Physician from UNITED STATES reported XELODA problem on Oct 12, 2006. Female patient, 66 years of age, was diagnosed with breast cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 2000 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374196-1
XELODA problem was reported by a Physician from UNITED STATES on Oct 12, 2006. Female patient, 52 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea. XELODA dosage: 4500 MG 2 PER DAY ORAL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374197-3
Physician from UNITED STATES reported XELODA problem on Oct 19, 2006. Male patient, 56 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died on 10/12/2006.

Xeloda Side Effects Report #5374198-5
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 19, 2006. Male patient, 64 years of age, was diagnosed with colon cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: colon cancer, colon cancer metastatic, metastases to liver. XELODA dosage: unknown. Patient died on 10/05/2006.

Xeloda Side Effects Report #5374199-7
Physician from UNITED STATES reported XELODA problem on Oct 20, 2006. Male patient, 62 years of age, was diagnosed with hepatic neoplasm malignant and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: hepatic neoplasm malignant. XELODA dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient died on 09/16/2006.

Xeloda Side Effects Report #5374200-0
XELODA problem was reported by a Health Professional from UNITED STATES on Oct 23, 2006. Female patient was diagnosed with bile duct cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 3000 MG DAILY ORAL. Patient recovered.

Xeloda Side Effects Report #5374201-2
Physician from UNITED STATES reported XELODA problem on Oct 23, 2006. Male patient, 48 years of age, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anorexia, ascites, deep vein thrombosis, dysgeusia, musculoskeletal pain, palmar-plantar erythrodysaesthesia syndrome, pancreatic carcinoma. XELODA dosage: unknown. Patient died on 08/24/2006.

Xeloda Side Effects Report #5374202-4
XELODA problem was reported by a Physician from UNITED STATES on Oct 24, 2006. Male patient, 88 years of age, weighting 179.0 lb, was diagnosed with colon cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1300 MG 2 PER 1 DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374203-6
Physician from UNITED STATES reported XELODA problem on Oct 24, 2006. Female patient, 53 years of age, weighting 170.0 lb, was diagnosed with metastatic neoplasm and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1800 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374204-8
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 24, 2006. Female patient, 67 years of age, weighting 112.0 lb, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1500 MG 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374205-X
Consumer or non-health professional from UNITED STATES reported XELODA problem on Oct 24, 2006. Female patient, 69 years of age, was diagnosed with breast cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 2500 MG DAILY ORAL. Patient recovered.

Xeloda Side Effects Report #5374206-1
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 24, 2006. Male patient, 79 years of age, weighting 164.9 lb, was diagnosed with colorectal cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: nausea. XELODA dosage: 1500 MG 1 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374207-3
Physician from UNITED STATES reported XELODA problem on Oct 30, 2006. Female patient, 59 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374208-5
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 30, 2006. Male patient, 42 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died on 10/28/2006.

Xeloda Side Effects Report #5374209-7
Health Professional from UNITED STATES reported XELODA problem on June 28, 2006. Male patient, 84 years of age, weighting 179.9 lb, was diagnosed with diarrhoea and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: constipation. XELODA dosage: 2500 MG DAILY ORAL. During the same period patient was treated with LOMOTIL, METOCLOPRAMIDE, HYZAAR. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374210-3
XELODA problem was reported by a Health Professional from UNITED STATES on July 03, 2006. Male patient, 67 years of age, weighting 143.1 lb, was diagnosed with rectal cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: dehydration, rectal cancer metastatic. XELODA dosage: 1500 MG 2 PER DAY ORAL. During the same period patient was treated with AVASTIN, OXALIPLATIN, ATENOLOL. Patient died on 06/24/2006.

Xeloda Side Effects Report #5374211-5
Consumer or non-health professional from UNITED STATES reported XELODA problem on July 05, 2006. Female patient, 64 years of age, was diagnosed with gastrointestinal carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: disease progression. XELODA dosage: unknown. Patient died on 06/25/2006.

Xeloda Side Effects Report #5374212-7
XELODA problem was reported by a Physician from UNITED STATES on July 06, 2006. Female patient, 79 years of age, weighting 108.0 lb, was diagnosed with biliary cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. XELODA dosage: 2150 MG DAILY 2 PER DAY ORAL. During the same period patient was treated with ATENOLOL, LISINORPIL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374213-9
Health Professional from UNITED STATES reported XELODA problem on July 13, 2006. Male patient was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: chest pain, dyspnoea. XELODA dosage: unknown. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374214-0
XELODA problem was reported by a Physician from UNITED STATES on July 19, 2006. Female patient, 49 years of age, weighting 188.1 lb, was diagnosed with breast cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea. XELODA dosage: 1500 MG 2 PER DAY ORAL. During the same period patient was treated with HERCEPTIN, LOTRIL, SYNTHROID, COUMADIN, NEXIUM. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374215-2
Physician from UNITED STATES reported XELODA problem on July 24, 2006. Male patient, 78 years of age, weighting 147.0 lb, was diagnosed with neoplasm malignant and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea, neutropenia. XELODA dosage: 1000 MG 2 PER DAY ORAL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374216-4
XELODA problem was reported by a Health Professional from UNITED STATES on July 28, 2006. Male patient, 32 years of age, weighting 284.0 lb, was diagnosed with colon cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: chronic sinusitis, headache. XELODA dosage: 5500 MG DAILY 2 PER DAY ORAL. Patient recovered.

Xeloda Side Effects Report #5374218-8
Physician from UNITED STATES reported XELODA problem on Aug 01, 2006. Male patient was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea, renal failure acute. XELODA dosage: unknown. During the same period patient was treated with OXALIPLATIN. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374219-X
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 07, 2006. Female patient was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374220-6
Physician from UNITED STATES reported XELODA problem on Aug 17, 2006. Male patient, 66 years of age, was diagnosed with neoplasm malignant and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: neoplasm malignant. XELODA dosage: unknown. Patient died on 07/23/2006.

Xeloda Side Effects Report #5374221-8
XELODA problem was reported by a Physician from UNITED STATES on Sept 06, 2006. Male patient, 59 years of age, was diagnosed with colon cancer metastatic and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: disease progression. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374222-X
Health Professional from UNITED STATES reported XELODA problem on Sept 13, 2006. Male patient was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: anorexia, pancytopenia. XELODA dosage: unknown. Patient recovered.

Xeloda Side Effects Report #5374223-1
XELODA problem was reported by a Physician from UNITED STATES on Sept 14, 2006. Female patient, 58 years of age, weighting 195.1 lb, was diagnosed with colon cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: thrombosis. XELODA dosage: 2000 MG 2 PER 1 DAY. During the same period patient was treated with DIOVAN, AVASTIN, CRESCORMON, LEVOXYL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374224-3
Physician from UNITED STATES reported XELODA problem on Sept 19, 2006. Female patient, 70 years of age, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: recall phenomenon. XELODA dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374225-5
XELODA problem was reported by a Physician from UNITED STATES on Sept 19, 2006. Female patient, 61 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died on 08/30/2006.

Xeloda Side Effects Report #5374226-7
Physician from UNITED STATES reported XELODA problem on Sept 27, 2006. Male patient, 48 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374227-9
XELODA problem was reported by a Health Professional from UNITED STATES on Sept 27, 2006. Female patient, 79 years of age, was diagnosed with breast cancer stage iv and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: breast cancer metastatic. XELODA dosage: unknown. During the same period patient was treated with PAMIDRONATE, ARANESP. Patient died on 09/13/2006.

Xeloda Side Effects Report #5374228-0
Consumer or non-health professional from UNITED STATES reported XELODA problem on Sept 27, 2006. Female patient was diagnosed with cerebrovascular accident and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: haemorrhage. XELODA dosage: unknown. During the same period patient was treated with COUMADIN. Patient recovered.

Xeloda Side Effects Report #5374371-6
XELODA problem was reported by a Physician from UNITED STATES on Jan 15, 2007. Male patient, 73 years of age, weighting 200.0 lb, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: pancreatic carcinoma. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374512-0
Health Professional from UNITED STATES reported XELODA problem on Dec 06, 2005. Female patient, 47 years of age, weighting 130.1 lb, was diagnosed with colorectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: thrombosis. XELODA dosage: 20000 MG 2 PER DAY ORAL. During the same period patient was treated with COUMADIN, LOVENOX, ACEBUTOLOL, ACTONEL, CALCIUM, CLARADIN, DOXYCYCLINE, LEVOTHYROXINE. Patient recovered.

Xeloda Side Effects Report #5374513-2
XELODA problem was reported by a Physician from UNITED STATES on Oct 10, 2006. Female patient, 41 years of age, was diagnosed with breast cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, pulmonary embolism. XELODA dosage: 2000 MG 2 PER DAY. During the same period patient was treated with DIOVAN, VIT B, ASPIRIN. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374516-8
Health Professional from UNITED STATES reported XELODA problem on May 02, 2006. Female patient, 70 years of age, weighting 160.5 lb, was diagnosed with ovarian cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: neutrophil count decreased. XELODA dosage: 900 MG 2 PER DAY ORAL. During the same period patient was treated with GEMCITABINE. Patient recovered.

Xeloda Side Effects Report #5374518-1
XELODA problem was reported by a Physician from UNITED STATES on May 01, 2006. Male patient, 68 years of age, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: hepatic failure, pancreatic carcinoma. XELODA dosage: 1000 MG/M2 2 PER DAY ORAL. Patient died on 04/26/2006.

Xeloda Side Effects Report #5374520-X
Physician from UNITED STATES reported XELODA problem on May 12, 2006. Male patient, 62 years of age, weighting 170.0 lb, was diagnosed with rectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea, pyrexia. XELODA dosage: 1950 MG 2 PER DAY ORAL. During the same period patient was treated with AVASTIN, CENTRUM, VITAMIN B6, OXALIPLATIN, LOMOTIL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374521-1
XELODA problem was reported by a Physician from UNITED STATES on May 12, 2006. Female patient was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: diarrhoea. XELODA dosage: unknown. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374522-3
Physician from UNITED STATES reported XELODA problem on May 12, 2006. Female patient, 76 years of age, weighting 125.0 lb, was diagnosed with pancreatic carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: pancreatic carcinoma. XELODA dosage: 500 MG 2 PER DAY ORAL. Patient died on 05/08/2006.

Xeloda Side Effects Report #5374525-9
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on May 15, 2006. Female patient, 63 years of age, weighting 183.0 lb, was diagnosed with breast cancer, atrial fibrillation and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: depression, heart rate, heart rate increased, palmar-plantar erythrodysaesthesia syndrome. XELODA dosage: 1000 MG/M2 2 PER DAY ORAL. During the same period patient was treated with COUMADIN. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374526-0
Physician from UNITED STATES reported XELODA problem on May 25, 2006. Male patient, 64 years of age, was diagnosed with rectal cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: rectal cancer. XELODA dosage: 1500 MG 1 PER 3 WEEK ORAL. Patient died on 05/23/2006.

Xeloda Side Effects Report #5374527-2
XELODA problem was reported by a Health Professional from UNITED STATES on May 24, 2006. Male patient, 85 years of age, weighting 134.0 lb, was diagnosed with oesophageal carcinoma and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: oesophageal carcinoma. XELODA dosage: 2500 MG DAILY, 2 PER DAY; ORAL. During the same period patient was treated with METHOCLOPRAMIDE, OMEPRAZOLE, LEVOTHYROXINE, ASPIRIN. Patient died on 05/08/2006.

Xeloda Side Effects Report #5374528-4
Pharmacist from UNITED STATES reported XELODA problem on May 24, 2006. Female patient was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374529-6
XELODA problem was reported by a Physician from UNITED STATES on May 25, 2006. Male patient, 84 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: gastric cancer. XELODA dosage: unknown. Patient died on 05/01/2006.

Xeloda Side Effects Report #5374530-2
Physician from UNITED STATES reported XELODA problem on May 25, 2006. Female patient, 71 years of age, weighting 213.0 lb, was diagnosed with colon cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: colorectal cancer metastatic, metastases to liver, metastases to lung. XELODA dosage: unknown. During the same period patient was treated with AVALIDE, GLIPIZIDE, CARDIZEM, METOPROLOL TARTRATE, PLAVIX, LOTENSIN, ZOCOR. Patient died on 05/19/2006.

Xeloda Side Effects Report #5374540-5
XELODA problem was reported by a Health Professional from UNITED STATES on June 02, 2006. Female patient, 61 years of age, weighting 207.0 lb, was diagnosed with breast cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: dysphagia. XELODA dosage: 1500 MG, 2 PER DAY;. During the same period patient was treated with CALTRATE, LASIX, CODEINE SUL, FENTANYL. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374550-8
Consumer or non-health professional from UNITED STATES reported XELODA problem on June 01, 2006. Female patient, 84 years of age, weighting 130.1 lb, was diagnosed with colon cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: vomiting. XELODA dosage: 1000 MG 2 PER DAY; ORAL. During the same period patient was treated with EVISTA, CELEBREX, VITAMIN, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Xeloda Side Effects Report #5374551-X
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on June 05, 2006. Female patient, 75 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: anaemia, bone marrow disorder, hot flush, malaise, nausea, platelet count decreased, pruritus. XELODA dosage: 500 MG 3 PER DAY; ORAL. During the same period patient was treated with XENICAL, ACETAMINOPHEN, SYNTHROID, FLOVENT, FLONASE. Patient recovered.

Xeloda Side Effects Report #5374552-1
Consumer or non-health professional from UNITED STATES reported XELODA problem on June 07, 2006. Male patient, 59 years of age, weighting 155.0 lb, was diagnosed with gastric cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: dyspnoea. XELODA dosage: 1500 MG 2 PER DAY; ORAL. Patient recovered.

Xeloda Side Effects Report #5374553-3
XELODA problem was reported by a Consumer or non-health professional from UNITED STATES on June 23, 2006. Female patient, 47 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: abscess. XELODA dosage: unknown. During the same period patient was treated with KYTRIL. Patient was hospitalized. Patient died on 05/09/2006.

Xeloda Side Effects Report #5374554-5
Pharmacist from UNITED STATES reported XELODA problem on June 29, 2006. Male patient was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374609-5
XELODA problem was reported by a Physician from UNITED STATES on Mar 23, 2007. Female patient, 80 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident. XELODA dosage: 2000 MG DAILY. Patient recovered.

Xeloda Side Effects Report #5374611-3
Physician from UNITED STATES reported XELODA problem on Mar 27, 2007. Male patient, 52 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374624-1
XELODA problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Male patient, 48 years of age, was treated with XELODA. XELODA dosage: unknown. Patient died.

Xeloda Side Effects Report #5374626-5
Physician from UNITED STATES reported XELODA problem on Apr 09, 2007. Female patient, 60 years of age, was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: breast cancer. XELODA dosage: unknown. Patient died on 01/05/2007.

Xeloda Side Effects Report #5374628-9
XELODA problem was reported by a Health Professional from UNITED STATES on Apr 12, 2007. Female patient, 70 years of age, was diagnosed with colon cancer and was treated with XELODA. After drug was administered, patient experienced the following problems/side effects: chest pain, constipation, diarrhoea, gallop rhythm present, heart rate irregular, hypokalaemia. XELODA dosage: 1000 MG 2 PER DAY ORAL. Patient was hospitalized. Patient recovered.

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Drug Information: Capecitabine

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a699003.html

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IMPORTANT WARNING:

When used in combination with anticoagulants ('blood thinners') such as warfarin (Coumadin), capecitabine can cause serious bleeding and death. Tell your doctor if you are taking warfarin or phenprocoumon. Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to capecitabine. If you experience any unusual bleeding or bruising, call your doctor immediately.

About your treatment

Your doctor has ordered the drug capecitabine to help treat your illness. The drug is taken by mouth with tablets. Take capecitabine with water within 30 minutes after eating a meal.

This medication is used to treat:

metastatic colorectal cancer
metastatic breast cancer

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for information.

Capecitabine is in a class of drugs known as antimetabolites. Capecitabine resembles a normal cell nutrient needed by cancer cells to grow. The cancer cells take up the capecitabine, which then interferes with their growth. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have.

Precautions

Before taking capecitabine,

tell your doctor and pharmacist if you are allergic to a capecitabine, fluorouracil, or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially those listed in the IMPORTANT WARNING section, antacids, folic acid, leucovorin, phenytoin (Dilantin), and vitamins.
tell your doctor if you have or have ever had heart, liver, or kidney disease.
women who are pregnant or breast-feeding should tell their doctors before they begin taking this drug. You should not plan to have children while receiving chemotherapy or for a while after treatments. (Talk to your doctor for further details.) Use a reliable method of birth control to prevent pregnancy.
tell your doctor if you are breast-feeding. Capecitabine can cause serious side effects in nursing infants.
do not have any vaccinations (e.g., measles or flu shots) without talking to your doctor.

Side effects

Side effects from capecitabine are common and include:

diarrhea
nausea
vomiting
stomach pain
constipation
weakness
tiredness
dizziness
headache
sleeplessness
dry or itching skin
dehydration

If you experience any of the following symptoms or the one listed in the IMPORTANT WARNING section, call your doctor immediately:

severe diarrhea (more than four bowel movements each day or diarrhea at night)
decreased appetite (complete loss of appetite or only able to eat occasionally)
severe vomiting (more than one time in a 24-hour period)
tingling, numbness, pain, redness, or swelling of the hands or feet
sores or pain in the mouth or throat
fever or infection (a temperature of 100.5 degrees F or greater)
chills
sore throat
chest pain
rash

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

Storage conditions

Keep capecitabine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Brand name(s):

Xeloda®

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