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Review Xigris Safety Reports submitted to FDA

Total Xigris reports: 272.
Xigris FDA safety alerts: 2005 .
Reported deaths: 219    Reported hospitalizations: 29.
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FDA Reported Xigris Side Effects: death, haemorrhage intracranial, thrombocytopenia, platelet count decreased, multi-organ failure, sepsis, activated partial thromboplastin time prolonged, international normalised ratio increased, septic shock, gastrointestinal haemorrhage, respiratory failure.
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Xigris Side Effects Report #5360586-X
Physician from UNITED STATES reported XIGRIS problem on June 11, 2007. Male patient, 46 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: hodgkin's disease, rectal haemorrhage, respiratory tract haemorrhage. XIGRIS dosage: unknown. Patient died on 01/01/2007.

Xigris Side Effects Report #5360632-3
XIGRIS problem was reported by a Physician from UNITED STATES on June 13, 2007. Female patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: multi-organ failure. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5360652-9
Physician from UNITED STATES reported XIGRIS problem on June 12, 2007. Female patient, 42 years of age, was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died on 06/10/2007.

Xigris Side Effects Report #5365383-7
XIGRIS problem was reported by a Physician from UNITED STATES on June 17, 2007. Female patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage intracranial. XIGRIS dosage: unknown. Patient died on 01/01/2007.


Xigris Side Effects Report #5365385-0
Physician from NEW ZEALAND reported XIGRIS problem on June 14, 2007. Female patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: eye disorder. XIGRIS dosage: unknown. Patient died on 06/01/2007.

Xigris Side Effects Report #5365391-6
XIGRIS problem was reported by a Physician from CANADA on June 14, 2007. Male patient, 62 years of age, was diagnosed with septic shock and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5365392-8
Physician from FRANCE reported XIGRIS problem on June 15, 2007. Male patient, 57 years of age, was diagnosed with septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. XIGRIS dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 06/15/2007.

Xigris Side Effects Report #5365395-3
XIGRIS problem was reported by a Physician from FRANCE on June 15, 2007. Male patient, 51 years of age, weighting 138.9 lb, was diagnosed with sepsis, septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, ischaemic stroke, meningorrhagia. XIGRIS dosage: unknown. During the same period patient was treated with LASIX, HYPNOVEL, NIMBEX, SUFENTA, NORADRENALINE, TAZOCILLINE, CIFLOX, ZYVOX. Patient died on 01/28/2007.

Xigris Side Effects Report #5369425-4
Physician from UNITED STATES reported XIGRIS problem on June 19, 2007. Male patient, 34 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. XIGRIS dosage: unknown. Patient recovered.


Xigris Side Effects Report #5369440-0
XIGRIS problem was reported by a Physician from UNITED STATES on June 18, 2007. Male patient, 55 years of age, was treated with XIGRIS. XIGRIS dosage: unknown. Patient died on 06/17/2007.

Xigris Side Effects Report #5369441-2
Physician from UNITED STATES reported XIGRIS problem on June 19, 2007. Male patient, 45 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: hepatic failure, intubation. XIGRIS dosage: unknown. Patient died on 05/06/2007.

Xigris Side Effects Report #5371738-7
XIGRIS problem was reported by a Physician from UNITED STATES on June 20, 2007. Male patient, 53 years of age, was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died on 06/15/2007.

Xigris Side Effects Report #5374458-8
Physician from UNITED STATES reported XIGRIS problem on June 21, 2007. Male patient, 60 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: multi-organ failure. XIGRIS dosage: unknown. Patient died on 06/01/2007.

Xigris Side Effects Report #5314838-X
XIGRIS problem was reported by a Physician from CANADA on Apr 24, 2007. Male patient, 75 years of age, was diagnosed with septic shock and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.


Xigris Side Effects Report #5316558-4
Physician from UNITED KINGDOM reported XIGRIS problem on Apr 22, 2007. Female patient, 59 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. XIGRIS dosage: unknown. Patient recovered.

Xigris Side Effects Report #5318290-X
XIGRIS problem was reported by a Physician from UNITED STATES on Apr 23, 2007. Female patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage. XIGRIS dosage: unknown. Patient died on 01/01/2007.

Xigris Side Effects Report #5319978-7
Physician from UNITED KINGDOM reported XIGRIS problem on May 03, 2007. Female patient, 62 years of age, weighting 154.3 lb, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5319981-7
XIGRIS problem was reported by a Physician from UNITED STATES on May 01, 2007. Female patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage, multi-organ failure. XIGRIS dosage: unknown. Patient died on 03/20/2007.

Xigris Side Effects Report #5322139-9
Physician from GERMANY reported XIGRIS problem on May 08, 2007. Male patient, 70 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: hepatic failure, renal failure, respiratory failure, sepsis. XIGRIS dosage: unknown. Patient died.


Xigris Side Effects Report #5324856-3
XIGRIS problem was reported by a Physician from UNITED STATES on May 09, 2007. Male patient, 55 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: acidosis, hypoventilation. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5324858-7
Physician from MEXICO reported XIGRIS problem on May 03, 2007. Male patient, 28 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage. XIGRIS dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died on 03/07/2007.

Xigris Side Effects Report #5324859-9
XIGRIS problem was reported by a Physician from UNITED STATES on May 08, 2007. Female patient, 60 years of age, was diagnosed with septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: chest pain, electrocardiogram st segment elevation, troponin increased. XIGRIS dosage: unknown. During the same period patient was treated with LEVOPHED. Patient recovered.

Xigris Side Effects Report #5324864-2
Physician from UNITED STATES reported XIGRIS problem on May 09, 2007. Male patient, 45 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: intubation, lower gastrointestinal haemorrhage, upper gastrointestinal haemorrhage. XIGRIS dosage: unknown. Patient died on 05/06/2007.

Xigris Side Effects Report #5324866-6
XIGRIS problem was reported by a Physician from UNITED STATES on May 09, 2007. Female patient, 23 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: septic embolus. XIGRIS dosage: unknown. During the same period patient was treated with LEVOPHED, VANCOMYCIN HYDROCHLORIDE. Patient died.

Xigris Side Effects Report #5330843-1
Physician from UNITED STATES reported XIGRIS problem on May 17, 2007. Female patient, 70 years of age, was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5333271-8
XIGRIS problem was reported by a Physician from CANADA on May 17, 2007. Female patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: infarction. XIGRIS dosage: unknown. Patient recovered.

Xigris Side Effects Report #5333273-1
Physician from UNITED STATES reported XIGRIS problem on May 17, 2007. Male patient, 90 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: respiratory failure, sepsis. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5334818-8
XIGRIS problem was reported by a Physician from UNITED KINGDOM on May 20, 2007. Male patient, 69 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. XIGRIS dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with NORADRENALINE, PARACETAMOL, HYDROCORTISONE. Patient recovered.

Xigris Side Effects Report #5334832-2
Physician from UNITED STATES reported XIGRIS problem on May 23, 2007. Male patient, 83 years of age, was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5334833-4
XIGRIS problem was reported by a Physician from UNITED STATES on May 22, 2007. Male patient was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage. XIGRIS dosage: unknown. Patient died on 01/01/2006.

Xigris Side Effects Report #5338446-X
Physician from IRELAND reported XIGRIS problem on May 22, 2007. Female patient, 61 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, platelet count decreased. XIGRIS dosage: 1.44 MG, EVERY HOUR. Patient died on 03/08/2007.

Xigris Side Effects Report #5338449-5
XIGRIS problem was reported by a Physician from GERMANY on May 23, 2007. Male patient, 40 years of age, was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died on 05/04/2003.

Xigris Side Effects Report #5284622-4
Physician from UNITED STATES reported XIGRIS problem on Mar 28, 2007. Female patient, 44 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage, thrombocytopenia. XIGRIS dosage: unknown. Patient recovered.

Xigris Side Effects Report #5284632-7
XIGRIS problem was reported by a Physician from FRANCE on Mar 23, 2007. Male patient, 51 years of age, weighting 138.9 lb, was diagnosed with sepsis, septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage. XIGRIS dosage: unknown. During the same period patient was treated with LASIX, HYPNOVEL, NIMBEX, SUFENTA, NORADRENALINE. Patient died on 01/28/2007.

Xigris Side Effects Report #5284633-9
Physician from reported XIGRIS problem on Mar 26, 2007. Female patient, 54 years of age, was diagnosed with septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, thrombocytopenia. XIGRIS dosage: 40 MG, OTHER. During the same period patient was treated with NORADRENALINE, DOBUTAMINE, FUROSEMIDE, NEXIUM, LINEZOLID, DEFLAMON, DALACIN C PHOSPHAT, URBASON. Patient recovered.

Xigris Side Effects Report #5284638-8
XIGRIS problem was reported by a Physician from GERMANY on Mar 23, 2007. Male patient, 45 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: multi-organ failure, sepsis, septic shock. XIGRIS dosage: 3.9 ML, EVERY HOUR. Patient died on 03/01/2007.

Xigris Side Effects Report #5284657-1
Physician from CANADA reported XIGRIS problem on Mar 27, 2007. Male patient was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5288431-1
XIGRIS problem was reported by a Physician from CANADA on Mar 29, 2007. Male patient was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5297632-8
Pharmacist from UNITED STATES reported XIGRIS problem on Apr 12, 2007. Male patient, 45 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haematoma, loss of consciousness. XIGRIS dosage: unknown. Patient recovered.

Xigris Side Effects Report #5299595-8
XIGRIS problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Female patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, sepsis. XIGRIS dosage: unknown. Patient died on 01/01/2007.

Xigris Side Effects Report #5299597-1
Physician from UNITED STATES reported XIGRIS problem on Apr 06, 2007. Male patient, 65 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: international normalised ratio increased, platelet count decreased. XIGRIS dosage: unknown. During the same period patient was treated with MILRINONE, LEVOPHED. Patient recovered.

Xigris Side Effects Report #5299598-3
XIGRIS problem was reported by a Physician from UNITED STATES on Apr 10, 2007. Male patient, 46 years of age, was diagnosed with septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, platelet count decreased. XIGRIS dosage: unknown. During the same period patient was treated with PLASMA. Patient recovered.

Xigris Side Effects Report #5300636-X
Physician from ARGENTINA reported XIGRIS problem on Apr 03, 2007. Male patient, 56 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: multi-organ failure. XIGRIS dosage: 24 MG/KG, EVERY HOUR. Patient died on 02/28/2007.

Xigris Side Effects Report #5304108-8
XIGRIS problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Female patient, 79 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, haemorrhage, sepsis, septic shock. XIGRIS dosage: unknown. During the same period patient was treated with ENOXAPARIN. Patient died.

Xigris Side Effects Report #5304480-9
Pharmacist from UNITED STATES reported XIGRIS problem on Apr 17, 2007. Male patient, 57 years of age, weighting 186.0 lb, was diagnosed with septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: facial palsy, intracranial haematoma, mental status changes. XIGRIS dosage: unknown. During the same period patient was treated with CUBICIN, FLUCONAZOLE, VANCOMYCIN, PEPCID, HALOPERIDOL. Patient was hospitalized and became disabled. Patient recovered.

Xigris Side Effects Report #5309821-4
XIGRIS problem was reported by a Physician from UNITED STATES on Apr 21, 2007. Female patient, 44 years of age, was diagnosed with septic shock, prophylaxis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis. XIGRIS dosage: unknown. During the same period patient was treated with LOVENOX. Patient recovered.

Xigris Side Effects Report #5309824-X
Physician from GERMANY reported XIGRIS problem on Apr 19, 2007. Male patient was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5253406-5
XIGRIS problem was reported by a Physician from AUSTRIA on Feb 22, 2007. Male patient, 60 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage intracranial. XIGRIS dosage: unknown. During the same period patient was treated with ANTITHROMBIN III, PENICILLIN, OPTINEM, ZYVOX, ANAEROBEX, SELEN, PANTOLOC, FRAGMIN. Patient was hospitalized. Patient died on 01/25/2007.

Xigris Side Effects Report #5253408-9
Physician from SPAIN reported XIGRIS problem on Feb 16, 2007. Male patient, 73 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, platelet count decreased. XIGRIS dosage: unknown. Patient recovered.

Xigris Side Effects Report #5253413-2
XIGRIS problem was reported by a Physician from UNITED STATES on Feb 21, 2007. Male patient, 47 years of age, was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died on 02/14/2007.

Xigris Side Effects Report #5256659-2
Physician from UNITED STATES reported XIGRIS problem on Feb 23, 2007. Male patient, 76 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression. XIGRIS dosage: unknown. Patient died on 02/22/2007.

Xigris Side Effects Report #5256661-0
XIGRIS problem was reported by a Physician from UNITED STATES on Feb 23, 2007. Male patient, 45 years of age, was diagnosed with sepsis and was treated with XIGRIS. XIGRIS dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died on 02/16/2007.

Xigris Side Effects Report #5256664-6
Physician from UNITED STATES reported XIGRIS problem on Feb 26, 2007. Male patient, 65 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: hepatic failure. XIGRIS dosage: unknown. Patient died on 01/01/2007.

Xigris Side Effects Report #5256710-X
XIGRIS problem was reported by a Physician from CANADA on Feb 27, 2007. Female patient was treated with XIGRIS. XIGRIS dosage: unknown. Patient died on 01/01/2007.

Xigris Side Effects Report #5261049-2
Physician from UNITED KINGDOM reported XIGRIS problem on Feb 26, 2007. Male patient, 87 years of age, weighting 174.2 lb, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: hypervolaemia. XIGRIS dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with CLEXANE. Patient recovered.

Xigris Side Effects Report #5261111-4
XIGRIS problem was reported by a Physician from UNITED STATES on Mar 02, 2007. Female patient, 68 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage. XIGRIS dosage: unknown. During the same period patient was treated with LEVOPHED, NEXIUM. Patient died on 01/01/2007.

Xigris Side Effects Report #5263899-5
Physician from UNITED KINGDOM reported XIGRIS problem on Mar 01, 2007. Male patient, 42 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. XIGRIS dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with ANTIBIOTICS, NORADRENALINE. Patient recovered.

Xigris Side Effects Report #5263905-8
XIGRIS problem was reported by a Physician from UNITED STATES on Mar 06, 2007. Female patient, 42 years of age, was diagnosed with urosepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. XIGRIS dosage: unknown. During the same period patient was treated with VASOPRESSIN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5263909-5
Physician from AUSTRALIA reported XIGRIS problem on Feb 26, 2007. Male patient, 50 years of age, was diagnosed with multi-organ failure and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: colonic polyp, diabetes mellitus, disorientation, hepatitis cholestatic, pyrexia, renal failure. XIGRIS dosage: unknown. During the same period patient was treated with VANCOMYCIN HYDROCHLORIDE, PENICILLIN G, CIPROFLOXACIN, CLINDAMYCIN, ANALGESICS, DIGOXIN, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5263910-1
XIGRIS problem was reported by a Physician from UNITED STATES on Mar 02, 2007. Female patient, 68 years of age, was diagnosed with sepsis, ulcer and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage, post procedural haemorrhage. XIGRIS dosage: unknown. During the same period patient was treated with LEVOPHED, NEXIUM. Patient died on 01/01/2007.

Xigris Side Effects Report #5263915-0
Physician from UNITED STATES reported XIGRIS problem on Mar 07, 2007. Male patient, 58 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: international normalised ratio increased. XIGRIS dosage: unknown. Patient recovered.

Xigris Side Effects Report #5267394-9
XIGRIS problem was reported by a Physician from SPAIN on Mar 07, 2007. Male patient, 73 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, thrombocytopenia. XIGRIS dosage: unknown. During the same period patient was treated with ENOXAPARIN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5267402-5
Physician from CANADA reported XIGRIS problem on Mar 09, 2007. Female patient, 49 years of age, weighting 132.3 lb, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: ventricular fibrillation. XIGRIS dosage: unknown. During the same period patient was treated with CEFTRIAXONE, TAZOCIN, AVELOX, PEPCID, LEVOPHED, VASOPRESSIN, VANCOMYCIN, INSULIN. Patient died on 02/14/2007.

Xigris Side Effects Report #5267450-5
XIGRIS problem was reported by a Physician from PORTUGAL on Mar 05, 2007. Male patient, 76 years of age, was diagnosed with sepsis, pneumonia and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: haemorrhage intracranial. XIGRIS dosage: unknown. During the same period patient was treated with ANTIBIOTICS, NORADRENALINE, RANITIDINE, ENOXAPARIN. Patient died on 02/24/2007.

Xigris Side Effects Report #5270258-8
Physician from CANADA reported XIGRIS problem on Mar 12, 2007. Male patient, 71 years of age, was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: sepsis. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5273948-6
XIGRIS problem was reported by a Physician from CANADA on Mar 16, 2007. Male patient, 71 years of age, weighting 224.9 lb, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: sepsis. XIGRIS dosage: unknown. During the same period patient was treated with MOXIFLOXACIN, AZITHROMYCIN, PANTOPRAZOLE, HEPARIN, NOREPINEPHRINE BITARTRATE, VASOPRESSIN. Patient died on 03/06/2007.

Xigris Side Effects Report #5278041-4
Physician from GERMANY reported XIGRIS problem on Mar 20, 2007. Male patient, 45 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: condition aggravated, multi-organ failure, sepsis, septic shock. XIGRIS dosage: 3.9 ML, EVERY HOUR. Patient died on 03/01/2007.

Xigris Side Effects Report #5278043-8
XIGRIS problem was reported by a Physician from UNITED STATES on Mar 21, 2007. Male patient was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: multi-organ failure. XIGRIS dosage: unknown. Patient died on 03/01/2007.

Xigris Side Effects Report #5278045-1
Physician from CANADA reported XIGRIS problem on Mar 21, 2007. Female patient was treated with XIGRIS. XIGRIS dosage: unknown. Patient died on 12/01/2006.

Xigris Side Effects Report #5278053-0
XIGRIS problem was reported by a Physician from CANADA on Mar 20, 2007. Male patient, 47 years of age, was diagnosed with septic shock and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: dialysis. XIGRIS dosage: unknown. Patient died.

Xigris Side Effects Report #5278060-8
Physician from UNITED STATES reported XIGRIS problem on Mar 20, 2007. Male patient, 58 years of age, was diagnosed with sepsis and was treated with XIGRIS. After drug was administered, patient experienced the following problems/side effects: international normalised ratio increased, multi-organ failure. XIGRIS dosage: unknown. Patient died on 03/08/2007.

Xigris Side Effects Report #5278061-X
XIGRIS problem was reported by a Physician from CANADA on Mar 20, 2007. Female patient, 53 years of age, was diagnosed with septic shock and was treated with XIGRIS. XIGRIS dosage: unknown. Patient died.

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