ZACTIMA Side Effects

6937774-1 | Colonic Fistula, Escherichia Urinary Tract Infection, Fall, Gastrointestinal Fistula, Pneumaturia
on Aug 23, 2010 Male patient from UNITED STATES , 64 years of age, weighting 233.8 lb, was diagnosed with glioblastoma and was treated with Zactima (View Usage). Patient experienced the following unwanted or unexpected effects: colonic fistula, escherichia urinary tract infection, fall (What is fall?), gastrointestinal fistula, pneumaturia. Zactima dosage: 100 Mg, Qd, Po. During the same period patient was treated with GLUCOSAMINE (View Glucosamine Review and Glucosamine Label ), XEPPRA (View Xeppra Review and Xeppra Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ), OXYCODONE HCL (View Oxycodone Hcl Review and Oxycodone Hcl Label ), PRILOSEC (View Prilosec Review and Prilosec Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ), ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), ZOFRAN (View Zofran Review and Zofran Label ). Patient was hospitalized.

6487193-X | Abasia, Cerebral Haemorrhage, Communication Disorder, Electrocardiogram Qt Prolonged, Fatigue, International Normalised Ratio Increased, Intracranial Haematoma, Middle Insomnia, Unresponsive To Stimuli
Patient was taking Zactima (View Usage). Patient had the following side effects: abasia, cerebral haemorrhage, communication disorder, electrocardiogram qt prolonged, fatigue, international normalised ratio increased, intracranial haematoma, middle insomnia, unresponsive to stimuli on Dec 09, 2009 from UNITED STATES Additional patient health information: Male patient , weighting 204.0 lb, was diagnosed with disease recurrence, glioblastoma multiforme and. Zactima dosage: 200 Mg Once Daily Po; 100 Mg Once Daily Po. During the same period patient was treated with KEPPRA (ANTI SEIZURE) (View Keppra (anti-seizure) Review and Keppra (anti-seizure) Label ), FLUOXITINE (DEPRESSION) (View Fluoxitine (depression) Review and Fluoxitine (depression) Label ), BACLOFEN (MUSCLE RELAXANT) (View Baclofen (muscle Relaxant) Review and Baclofen (muscle Relaxant) Label ), WARFARIN (ANTICOAGULANT) (View Warfarin (anticoagulant) Review and Warfarin (anticoagulant) Label ), ZOFRAN (PRN FOR NAUSEA) (View Zofran (prn For Nausea) Review and Zofran (prn For Nausea) Label ). Patient was hospitalized.

6023453-4 | Asthenia, Disease Progression, Neurological Decompensation, Peripheral Motor Neuropathy
Adverse event was reported on Dec 26, 2008 by a Male patient taking Zactima (View Usage) (Dosage: 300mg Qd Daily X 28 Days Po) was diagnosed with glioblastoma multiforme and. Location: UNITED STATES , weighting 141.3 lb, After Zactima was administered, patient had the following side effects: asthenia, disease progression, neurological decompensation, peripheral motor neuropathy. During the same period patient was treated with HYDREA (500mg Po Bid Bid X 28 Days Po) (View Hydrea Review and Hydrea Label ), GLEEVEC (400mg Qd Daily X 28 Days Po) (View Gleevec Review and Gleevec Label ), LAMICTAL (View Lamictal Review and Lamictal Label ), KEPPRA (View Keppra Review and Keppra Label ), VALTREX (View Valtrex Review and Valtrex Label ), COLACE (View Colace Review and Colace Label ), METAMUCIL (View Metamucil Review and Metamucil Label ), DECADRON (View Decadron Review and Decadron Label ).

6003586-9 | Asthenia, Disease Progression, Peripheral Motor Neuropathy
on Dec 12, 2008 Male patient from UNITED STATES , weighting 141.3 lb, was diagnosed with glioblastoma multiforme and was treated with Zactima (View Usage). Patient experienced the following unwanted or unexpected effects: asthenia, disease progression, peripheral motor neuropathy. Zactima dosage: 300mg Qd Daily X 28 Days Po. During the same period patient was treated with GLEEVEC (400mg Qd Daily X 28 Days Po) (View Gleevec Review and Gleevec Label ), HYDREA (500mg Po Bid Bid X 28 Days Po) (View Hydrea Review and Hydrea Label ), LAMICTAL (View Lamictal Review and Lamictal Label ), KEPPRA (View Keppra Review and Keppra Label ), VALTREX (View Valtrex Review and Valtrex Label ), COLACE (View Colace Review and Colace Label ), METAMUCIL (View Metamucil Review and Metamucil Label ), DECADRON (View Decadron Review and Decadron Label ). Patient was hospitalized.


6000210-6 | Asthenia, Disease Progression, Peripheral Motor Neuropathy
on Dec 11, 2008 Male patient from UNITED STATES , weighting 141.3 lb, was diagnosed with glioblastoma multiforme and was treated with Zactima (View Usage). Patient had the following side effects: asthenia, disease progression, peripheral motor neuropathy. Zactima dosage: 300mg Qd Daily X 28 Days Po. During the same period patient was treated with GLEEVEC (400mg Qd Daily X 28 Days Po) (View Gleevec Review and Gleevec Label ), HYDREA (500mg Po Bid Bid X 28 Days Po) (View Hydrea Review and Hydrea Label ), LAMICTAL (View Lamictal Review and Lamictal Label ), KEPPRA (View Keppra Review and Keppra Label ), VALTREX (View Valtrex Review and Valtrex Label ), COLACE (View Colace Review and Colace Label ), METAMUCIL (View Metamucil Review and Metamucil Label ), DECADRON (View Decadron Review and Decadron Label ). Patient was hospitalized.

5862765-1 | Confusional State, Diarrhoea, Disease Progression, Dizziness, Nausea, Postoperative Fever, Urinary Incontinence
Patient was taking Zactima (View Usage). After Zactima was administered, patient had the following side effects: confusional state, diarrhoea, disease progression, dizziness (What is dizziness?), nausea (What is nausea?), postoperative fever, urinary incontinence (What is urinary incontinence?) on Aug 27, 2008 from UNITED STATES Additional patient health information: Male patient , 40 years of age, weighting 172.0 lb, was diagnosed with glioblastoma multiforme and. Zactima dosage: Zactima300mg Qd. During the same period patient was treated with HYDROXYUREA (Hyroxyurea 500mg Bid) (View Hydroxyurea Review and Hydroxyurea Label ), GLEEVEC (500mg Bid) (View Gleevec Review and Gleevec Label ), LEXAPRO (View Lexapro Review and Lexapro Label ), DILANTIN (View Dilantin Review and Dilantin Label ). Patient was hospitalized.

5696577-9 | Convulsion, Hyponatraemia, Pyrexia
Adverse event was reported on Apr 04, 2008 by a Male patient taking Zactima (View Usage) (Dosage: 100mg Po Qd) was diagnosed with glioblastoma multiforme and. Location: UNITED STATES , 60 years of age, weighting 165.3 lb, Patient experienced the following unwanted or unexpected effects: convulsion, hyponatraemia, pyrexia. During the same period patient was treated with GLEEVEC (400mg Po Qd) (View Gleevec Review and Gleevec Label ), HYDROXYUREA (500mg Po Bid) (View Hydroxyurea Review and Hydroxyurea Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ), DECADRON (View Decadron Review and Decadron Label ), NEXIUM (View Nexium Review and Nexium Label ), KEPPRA (View Keppra Review and Keppra Label ). Patient was hospitalized.

5575031-9 | Bacteraemia, Bacterial Sepsis, Duodenal Ulcer, Gastric Ulcer, Hypotension, Leukopenia, Pancytopenia, Refusal Of Treatment By Relative, Respiratory Distress
on Dec 21, 2007 Male patient from UNITED STATES , 63 years of age, weighting 243.4 lb, was diagnosed with glioblastoma multiforme, brain oedema and was treated with Zactima (View Usage). Patient had the following side effects: bacteraemia, bacterial sepsis, duodenal ulcer, gastric ulcer, hypotension, leukopenia, pancytopenia, refusal of treatment by relative, respiratory distress. Zactima dosage: 200 Mg Qd Po. During the same period patient was treated with DECADRON (8 Mg Po Bid) (View Decadron Review and Decadron Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), ATENOLOL (View Atenolol Review and Atenolol Label ), ATOVAQUONE SUSPENSION (View Atovaquone Suspension Review and Atovaquone Suspension Label ), CARDURA (View Cardura Review and Cardura Label ), FOLIC ACID (View Folic Acid Review and Folic Acid Label ), KEPPRA (View Keppra Review and Keppra Label ), LANTUS (View Lantus Review and Lantus Label ). Patient was hospitalized.