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The decline was a result of certain quality actions and inventory losses, as well as a difficult year-over-year margin contribution comparison, driven by strong margin contribution from U.S. net sales of the oncolytic oxaliplatin in 2010 ...

and oxaliplatin), the Progression Free Survival (PFS) rate at one year was similar to that seen in the standard therapy arm for patients who received the modified FOLFOX6 regimen alone. The safety profile of ZALTRAP was similar to what was ...

BACKGROUND: D2 gastrectomy is recommended in US and European guidelines, and is preferred in east Asia, for patients with resectable gastric cancer. Adjuvant chemotherapy improves patient outcomes after surgery, but the benefits after a D2 ...

Among the three medications under evaluation, the committee felt that evidence failed to establish that bevacizumab when administered with non-oxaliplatin chemotherapy improved overall survival. Treatment with cetuximab and panitumumab were not found to be ...

February 8, 2012 — In patients with operable gastric cancer, adjuvant chemotherapy with capecitabine and oxaliplatin "should be considered a new treatment option," according to Asian investigators. In a phase 3 trial, they found that a 6-month course of ...

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The drug oxaliplatin is a major reason the prognosis for metastatic colon cancer has gone from an expected survival of several months to a couple years. Unfortunately, the drug can also carry with it debilitating neurological side effects, which generally ...

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January 31, 2012 (San Francisco, California) — Long-term results from the French ACCORD 12 trial indicate that the addition of oxaliplatin to capecitabine plus radiotherapy provides no additional survival benefit and increases toxicity in patients with ...

He had 7 rounds of Oxaliplatin and Xeloda between July and Christmas. He responded well with his swallowing issues gone after the 1st week of chemo and improving periodic scans. We were able to take a wonderful 16 day Mediterranean Cruise in late Oct ...

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Stage III colon cancer patients in the general population who receive adjuvant treatment for the disease have an improved rate of survival when oxaliplatin is added to 5-fluorouracil (5FU), according to a study published Jan. 20 in the Journal ...

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By the time he walked out, only his eyes and upper nose were visible. Oncologists began using the chemo drug oxaliplatin about seven years ago to help boost the effects of the drug 5-FU, the established treatment for colorectal cancer. Oxaliplatin causes a ...

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Please determine the molar mass in grams/ mole of: Carboplatin-C6H12N2O4Pt Cisplatin-Cl2(NH3)2Pt Oxaliplatin- C8H14N2O4Pt

My father in his early 50's got diagnosed with Colon cancer stage 3. Had surgery about 7 weeks ago. VERY little has spread past his colon wall to his lymph nodes (less than 3) His chemo is about to start in 4 days through a PICC line. The medicine in the chemotherapy is Oxaliplatin, Leucovotin, 5-Fluorouracil insfusion. He'll be in chemo for 2 months, the radiation with chemo and then chemo... Is this kind of treatment good for this stage of colon cancer? More information on the drugs?? Cou

I use the mouthwashes the hospital gave me, and have also been sucking the Strepsils with the anaesthetic action in them...all to no avail. Obviously the lump in my throat is the same sort of side effect as the mouth ulcers (I also get heartburn) but it gets all 'cloggy' with what feels like catarrh, and then it feels almost like I'm going to choke. What on earth can I do? The hospital prescribed Piriton, but I only started taking it today, so it won't kick in for a few days I guess. I just

Surgery has been done with clear margins, but with spread to two lymph nodes. The patient is undergoing chemotherapy now with epirubicin and oxaliplatin (infusion) and oral Xeloda (two tablets twice a day for 14 days during each cycle). How long will she live?

I have been told many figures and I am so confused now. A link to buy it online, would be appreciated as well. Thnx

I would like to make my sister comfortable as possible during this ordeal. She is amazing. Has mastisized colon cancer. has gone through operation, other, weaker chemo and now is getting stents in both kidneys and about to start oxaliplatin.

....I'm going to be having fortnightly doses of Oxaliplatin and Fleurouracil (not sure if I spelt the last one right!) for six months Is there anyone out there who has experience of this type of chemo, if so, how did it affect you? Did you work at the time? I've been told of all the possible side effects, but haven't spoken to anyone with experience of it. Do you experience any side effects from the start, or does it tend to accumulate, and the side effects get worse? I've also been told tha

apparently i'm supposed to avoid these, but I don't really know what they are. Amiodarone (Cordarone) Bortezomib (Velcade) Cisplatin & Oxaliplatin Colchicine (extended use) Dapsone Didanosine (ddI, Videx) Dichloroacetate Disulfiram (Antabuse) Gold salts Leflunomide (Arava) Metronidazole/Misonidazole (extended use) Nitrofurantoin (Macrodantin, Furadantin, Macrobid) Nitrous oxide (inhalation abuse or Vitamin B12 deficiency) Perhexiline (not used in U.S.) Pyridoxine (mega dose of Vitamin B6) Sta

It's stage 3 in colon and 4 in the lung. The doctor decided to use Folfax oxaliplatin and capecitabine also called xalada. Is this a good option? Well I guess I would like to know side effects of this treatment...

Does anyone know if the generic drug of Oxaliplatin manufactured by Dabur Pharma Limited,India , is as effective as the branded Oxaliplatin drug?

my father, aged 57 years, weight: 78 kgs Past History: 30/07/2004: colorectal anal cancer. APR surgery with colostomy 12/08/2004: cycle of 3 Chemo prescribed by oncology physician, drugs prescribed: oxaliplatin, leucovorin etc. 3/11/2004: Repeat cycle of above 3 chemo with radiation therapy. 25/06/2008: little raised CEA around 25. Whole body PET Scan is normal. Now my father has re-occurence of cancer with badly damaged liver & a condition called hepatomegaly with metastasis. its

Patient had colon cancer and a metastasis on the liver..She had a successful surgery a year ago and a Chemoterapy during the same year(with Oxaliplatin)..She has tomography once in 3 months.All was normal.. patient's blood measurements and tomogrophy was clean 3 months ago.. But 2cm spot on the liver is now realized in the last tomography results.Can it be a new metastasis or sth? It doesnt seems to be normal..Can a tumour grow during the 3 months so rapidly? Thanks for your urgent replies!.

I start my chemo on Monday and I would just like to actually talk (e-mail) someone who has actually taken this combination of drugs.

My sister had stage IIIC colon cancer last year, and went through eight cycles of chemo of oxaliplatin and xeloda. Last week a polyp with the same cancerous cells was found. It was removed and she was told she will need chemo. How many times may she need to have it?

My husband has stage 4 colon cancer with mets to his liver and base of lungs. He is taking chemo oxaliplatin with oral pill xeloda. He has constant back pain and sleeplessness. His backpain aggravates while lying down. Actually it was his back pain that led to a thorough investigation that found his cancer. Please tell me whether there is any cure for this cancer whether in allopathy or inalternative medicine. He is physically active and was fit till diaganosed.

is it similar to cisplatin mechanism?

I'm a 21 yr old female and was on Xeloda and oxaliplatin for colon cancer for 6 months until a couple of weeks ago. The skin on my hands and feet went really dark and dry and cracked. The skin on my hands is now peeling off, showing lighter coloured skin underneath. Is that just dry skin peeling off that shouldn't happen, or is it the horrible dark skin coming off and it going back to normal? It's not very sore, just when I bend my fingers, etc. Thanks

she is on a 6 month course of chemo being given oxaliplatin and 5fu the side effects are pretty bad and having trouble falling asleep is a huge deal she also watches the clock all day thinking of when she will going to bed and when it comes close she gets really agitated she wont have a nap during the day when she needs to because she thinks if she does that she wont sleep at night. I desperately need some ideas and techniques she could use to help her fall asleep. thank you so much for all yo

I finished colon cancer tx one month ago. The oxaliplatin left my hands and feet severely neuropathic. I used sunscreen--but missed spots on my feet. It has been a week today--they have not blistered--but in fact, the spots (@6" in length x 4") have turned purple. Because of the neuropathy--I dont know what is normal progression of this sunburn. Im a redhead and fair skin--Ive had my share of severe sunburns in my life---none ever didnt blister or turn purple. Thanks for any insight or informa

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