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A new bone-targeting agent, denosumab, a receptor activator of nuclear factor κB ligand (RANKL) antagonist, showed a modest reduction in SREs in comparison to zoledronic acid in patients with bone metastases. Other promising novel agents are ...

Reclast (zoledronic acid) is an injectable medication manufactured by Novartis, which was approved in 2007 as a once-a-year osteoporosis treatment, generating approximately $580 million in sales in 2010.

"The reported findings support its use as an alternative to zoledronic acid [Novartis' bone drug Zometa], but do not support its broad use as a preventive agent for bone metastases in prostate cancer," the editorial stated. As EvaluatePharma ...

The new drugs are Salmeterole to cure asthma, Riluzole to cure Amyotrophic lateral (ALS), Letrozole to cure Aromatize and breast cancer, Zoledronic acid to prevent Osteoporose, Botulinum toxin to cure skin diseases and Antihemophilic Factor VII for coagulation.

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So I'm doing my dissertation about postmenopausal osteoporosis.. So far, compliance with oral bisphosphonates is very poor. So could you think that IV zoledronic acid may be the patients dream in the future? Since it only used for once a year .. instead having oral tablets everyday.. What do you think about that? any pros and cons?

Please help! Mom has suffered osteoporosis for many years and seems now it just kept getting worst. Have gone to expensive hospitals abroad that gave her nothing but medication that made her sick /faint and vommiting. I am concern the doctor gave her fosamax that can cause jaw death. Did some research on a better solution : Found : Zoledronic acid through I V drip once a year . Does anyone knows anything about this ? good or bad ? any input will be appreciated. Replacing lost progesterone

The reaction of 1H-Imidazole-1H-Acetic acid with Phosphorous acid and Phosphorous oxy chloride. I want more interested to know the reaction mechanism of this step.

I'm 27 and have oesteoporosis. I used to have pamidronate infusions and suffered quite serious side effects each time. Fainting, feeling/being sick, dopey e.t.c. The last time I had it I ended up in hospital having had two seizures! My doctors recommended this annual intravenous medication, but my understanding is that it's more powerful than the other stuff, so surely the side effects are worse. Anyone had them?

hello people..my mother had a breast cancer operation 5 yrs ago. the doctor had to remove a breast to stop the spreading of the disease..then she had a chemotherapy session throughout these years..last year (13 dec) the doctor dectected the presence of a bone cancer...and had to operate once again..mum is still sick. Yesterday she went to a doctor,.the latter said that mum got water in her lungs and she got maybe 2 weeks to live :( today mum went to the hospital to have an injection call " Z

patient was given zoledronic acid 10 days back she is complaining of severe leg muscle pain , no relief with anti-inflammatory,

MRM was done in the year may 1999.Stage was T2 N1.ER not detected PR 30%positive.Received chemotherapy (Epirubicin) and rdiotherapy after surgery.She has taken Temoxyphen for 5 years.She was under regular follow up at cancer hospital Bhopal.Now her bone scan shows multiple bony mets at shoulders,L3AND L5 vertibrae.She has recieved recieved radiation on LA for 21 days.Now the doctors has dvised to take chemotherapy taxanes or docetroxel. She has also recieved two doses of Zoledronic Acid.Presnt

my father is diagnosed with Gleason IV adenocarcinoma of the prostate with slight bone metastases to ischium and L11-L12 vertebrea.. i want to know if there is any effective treatment for this type of cancer. He underwent bilateral orchiectomy and is taking bicalutamide tablets (50 mg)... He also had an injection of zoledronic acid 4 mg I want to know if these treatments are the best available. OR Sir, is it not treatable.. if it, can u tell me the life span.. We are

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