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What symptoms can Valproate cause?

Valproate Safety Information and Side Effects

Valproate Safety Information

Convulsion ( 158 reports)    ➢ More

Convulsion, Electrocardiogram Abnormal, Cerebral Atrophy

This case suggests a potential Valproate Sodium Convulsion side effect(s) that can have serious consequences. A 2-year-old female patient from JP (weight:NA) was diagnosed with the following health condition(s): epilepsy and used Valproate Sodium (dosage: NA) starting NS. Soon after starting Valproate Sodium the patient began experiencing various side effects, including:
  • Convulsion
  • Electrocardiogram Abnormal
  • Cerebral Atrophy
Drugs used concurrently:
  • Midazolam
  • Although Valproate Sodium demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Convulsion, may still occur.

    Somnolence ( 62 reports)    ➢ More

    Myoclonus, Hyperammonaemic Encephalopathy, Somnolence, Confusional State, Disorientation, Dysarthria, Ammonia Increased

    Adverse event was reported on Mar 19, 2014 by a Female taking Valproate Salt Not Specified (Dosage: NA) was diagnosed with and. Location: COUNTRY NOT SPECIFIED , 47 years of age, Directly after treatment started, patient experienced the unwanted or unexpected Valproate side effects: myoclonus, hyperammonaemic encephalopathy, somnolence, confusional state, disorientation, dysarthria, ammonia increased.
    Associated medications used:
    • Flupenthixol Dihydrochloride (flupenthixol Dihydrochloride)
    • Quetiapine (quetiapine)
    The patient was hospitalized.

    Coma ( 52 reports)    ➢ More

    Pyrexia, Decreased Appetite, Vomiting, Rash Erythematous, Hepatotoxicity, Hepatic Encephalopathy, Coma, Blood Pressure Increased, Clonic Convulsion

    This Coma problem was reported by a health professional from LK. A 6-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): complex partial seizures.On NS a consumer started treatment with Valproate Sodium (dosage: NA). The following health products were being taken at the same time: NA. When commencing Valproate Sodium, the patient experienced the following unwanted symptoms /side effects:
    • Pyrexia
    • Decreased Appetite
    • Vomiting
    • Rash Erythematous
    • Hepatotoxicity
    • Hepatic Encephalopathy
    • Coma
    • Blood Pressure Increased
    • Clonic Convulsion
    The patient was hospitalized. Although all health products are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Coma, may become evident only after a product is in use by the general population.

    Confusional State ( 52 reports)    ➢ More

    Myoclonus, Hyperammonaemic Encephalopathy, Somnolence, Confusional State, Disorientation, Dysarthria, Ammonia Increased

    A case of a 47-year-old female patient (weight: NA) from COUNTRY NOT SPECIFIED was presented. The patient developed the following symptoms/conditions: bipolar disorder and was treated with Valproate Salt Not Specified (dosage: NA) starting NS. Concurrently used drugs:
  • Flupenthixol Dihydrochloride (flupenthixol Dihydrochloride)
  • Quetiapine (quetiapine)
  • Soon after that, the subject experienced the following of symptoms:
    • Myoclonus
    • Hyperammonaemic Encephalopathy
    • Somnolence
    • Confusional State
    • Disorientation
    • Dysarthria
    • Ammonia Increased
    The patient was hospitalized. This opens a possibility that Valproate Salt Not Specified could cause Confusional State and that some female subjects may be more susceptible.

    Epilepsy ( 47 reports)    ➢ More

    Epilepsy, Hypomania, Cognitive Disorder, Confusional State, Attention Deficit/hyperactivity Disorder, Illogical Thinking, Confabulation

    on Nov 26, 2013 a Female from COUNTRY NOT SPECIFIED , 62 years of age, was diagnosed with and was treated with Valproate Sodium. Directly after treatment started, patient experienced the unwanted or unexpected Valproate side effects: epilepsy, hypomania, cognitive disorder, confusional state, attention deficit/hyperactivity disorder, illogical thinking, confabulation. Valproate Sodium dosage: NA.
    Associated medications used:
    • Disulfiram (Daily)
    • 4-amino-3-hydroxybutyric Acid (Daily)
    The patient was hospitalized.

    Common Valproate Side Effects

    Click to view detailed reports:

    Convulsion (159)
    Somnolence (62)
    Confusional State (52)
    Coma (52)
    Pyrexia (47)
    Epilepsy (47)
    Hyperammonaemia (46)
    Overdose (42)
    Thrombocytopenia (37)
    Neutropenia (34)
    Vomiting (33)
    Agitation (32)
    Grand Mal Convulsion (32)
    Toxicity To Various Agents (31)
    Cognitive Disorder (31)
    Hypotension (31)
    Fatigue (30)
    Pleural Effusion (30)
    Aggression (29)
    Hyperammonaemic Encephalopathy (29)
    Encephalopathy (28)
    Hepatotoxicity (28)
    Suicide Attempt (27)
    Sudden Unexplained Death In Epilepsy (27)
    Dyspnoea (27)
    Tremor (27)
    Condition Aggravated (27)
    Hyponatraemia (26)
    Abnormal Behaviour (25)
    Ammonia Increased (25)
    Electroencephalogram Abnormal (25)
    Delirium (24)
    Intentional Overdose (24)
    Dizziness (23)
    Alanine Aminotransferase Increased (23)
    Tachycardia (22)
    Gait Disturbance (22)
    Nausea (21)
    Status Epilepticus (21)
    Oedema Peripheral (20)
    Foetal Anticonvulsant Syndrome (20)
    Dysmorphism (19)
    Rash (19)
    Loss Of Consciousness (19)
    Anaemia (19)
    Abdominal Pain (19)
    Metabolic Encephalopathy (18)
    Fall (18)
    Aspartate Aminotransferase Increased (18)
    Dysarthria (18)

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    Valproate Forum

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